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Specialized Transduction
Specialized Transduction

... prophage. The second excises a segment of the prophage together with an adjacent segment of host DNA from the host chromosome (abnormal excision; Fig. 1). Subsequent work has shown that prophage insertion requires a phage-encoded site-specific recombinase, integrase, that promotes recombination betw ...
A Twist-like bHLH gene is a downstream factor of an
A Twist-like bHLH gene is a downstream factor of an

... 1997). In our previous comprehensive studies, we could not find any genes that are expressed specifically in both TVCs and mesenchyme at the tailbud stage, whereas many genes expressed in muscle cells were also found to be expressed in TVCs, suggesting that TVCs and muscle cells share some features ...
Kasiemobi Udo-okoye - The Genomics of Smoking Addiction
Kasiemobi Udo-okoye - The Genomics of Smoking Addiction

... cause smoking, the occurrence of regular smoking is not decreasing as quickly as is it could. Boardman and his colleagues conducted research exploring the effect of public policy on the extent to which genes influence smoking desistance. Using a sample of adult twins (n mz = 363, n dz = 233) from a ...
Navigating the HapMap - Oxford Academic
Navigating the HapMap - Oxford Academic

... a difference in frequency between cases and controls, and hence an association will be seen with the trait in question. How near these polymorphisms need to be to the disease allele on average is still somewhat open to debate [4**], but is generally dependent on the population history of the sample, ...
Functional Analysis of Genes Implicated in Down Syndrome: 2
Functional Analysis of Genes Implicated in Down Syndrome: 2

... hand more frequently for the majority of the six primary handedness items in Annett’s questionnaire; or (3) if they used their left hand more frequently in the majority of an extended 11-item handedness questionnaire. In 4.68% of cases, participants had conflicting classifications across the three cri ...
Hemoglobin research and the origins of molecular
Hemoglobin research and the origins of molecular

... Roughton, and others in the last century and has been reviewed in detail.10,11 More recently elucidated was how this finely tuned system is regulated via heterotropic interactions with other molecules, such as protons, anions, and bisphosphosphoglyceric acid (2,3 BPG or, in the older convention, 2,3 ...
Modeling Trabecular Microstructure Evolution via Genetic Algorithm by Samuel W. L. Shames
Modeling Trabecular Microstructure Evolution via Genetic Algorithm by Samuel W. L. Shames

Article A Distinct Mitochondrial Genome with DUI
Article A Distinct Mitochondrial Genome with DUI

... (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] ...
Artificial selection on introduced Asian haplotypes shaped the
Artificial selection on introduced Asian haplotypes shaped the

... Asian pigs, and body length from European pigs [14,16]. With the advent of genomic selection [17], genetic progress is expected to speed up even more. The design of a 60 K SNPchip for pigs in 2009 [18] and the publication of the pig reference genome in 2012 [19] greatly contributed to the applicabil ...
Educational Items Section Malignant blood diseases Atlas of Genetics and Cytogenetics
Educational Items Section Malignant blood diseases Atlas of Genetics and Cytogenetics

... • t(9;22)(q34;q11) • chromosome 22 appears shorter and was called Philadelphia chromosome (noted Ph) • translocates (part of) an oncogene, ABL, sitting usually in 9q34, next to (part of) another oncogene, BCR (breakpoint cluster region), in 22q11 --> production of a hybrid gene 5' BCR-3'ABL • the no ...
Myb genes enhance tobacco trichome production
Myb genes enhance tobacco trichome production

... accessibility to visual inspection and its relatively large size. In the laboratory, trichomes are non-essential and thus can be genetically manipulated without a reduction in plant viability. A number of mutants lacking or producing fewer, aberrant, or mis-positioned trichomes have been isolated fr ...
20. Transposable Genetic Elements
20. Transposable Genetic Elements

... indication of when in the seed's development the breakage occurred. A small white area suggests that the break came late in development, because it gave rise to only a small number of affected cells. A large patch suggests an early break, because many descendant cells are affected. The bottom seed i ...
Natural Selection, Infectious Transfer and the Existence Conditions
Natural Selection, Infectious Transfer and the Existence Conditions

... Overview: In this article, we use mathematical models and computer simulations to explore the existence conditions of plasmids. The most reasonable interpretation of the available evidence is that plasmids cannot be maintained solely by horizontal transfer in single populations. We therefore explore ...
CAIcal: A combined set of tools to assess codon usage adaptation
CAIcal: A combined set of tools to assess codon usage adaptation

... that most of E4 overlaps with E2, that the mature E1^E4 protein contains a few amino acids from E1 and that the splice sites are not strictly conserved, makes it difficult to determine the true E4 sequence in silico. The E4 PVs genes available in the databases are therefore very different in length ...
Approaches to Repeat Finding
Approaches to Repeat Finding

... Cornell Genomics Forum, 2005-03-18 ...
beckwith-wiedemann syndrome
beckwith-wiedemann syndrome

... result does not rule out the diagnosis of BWS. BWS patients may have CDKN1C mutations (5% of sporadic and 40% of familial cases) [please contact us to arrange this testing]. Or they may have somatic mosaicism or other epigenetic alterations, not currently assessed in the Molecular Genetics Laborator ...
In hemoglobin Tocucci there was a replacement of the amino acid
In hemoglobin Tocucci there was a replacement of the amino acid

... Which methods of human genetics you have to use for diagnosis of Edwards syndrome? A. Genealogy method. B. Twin method C. Dermatoglyphics D. Pedigree Analysis. E. Cytogenetical method. ANSWER: E Which methods of human genetics you have to use for diagnosis of Turner syndrome? A. Genealogy method. B. ...
In hemoglobin Tocucci there was a replacement of the amino acid
In hemoglobin Tocucci there was a replacement of the amino acid

... In hemoglobin Tocucci there was a replacement of the amino acid histidine to tyrosine. What kind of mutation is this A. Genomic mutation. B. Aneuploidy. C. Polyploidy. D. Inversion. E. Gene (point) mutation. ANSWER E In hemoglobin Tocucci there was a replacement of the amino acid histidine to tyrosi ...
Comparison of two codon optimization strategies to enhance
Comparison of two codon optimization strategies to enhance

... levels of their cognate tRNAs species in the cell, can reduce the translation rate and induce translation errors with a significant impact on the economy of the production process [5, 6]. In the past decade, a high number of genes have been re-designed to increase their expression level [1–3, 7†...
the lysis/lysogeny switch in phage \lambda
the lysis/lysogeny switch in phage \lambda

... with no cooperativity does not lead to the same switch-like behaviour. ...
Chapter 15 ppt
Chapter 15 ppt

... Behavior of a Chromosome Pair • In one experiment, Morgan mated male flies with white eyes (mutant) with female flies with red eyes (wild type) – The F1 generation all had red eyes – The F2 generation showed the 3:1 red:white ...
The biased nucleotide composition of the HIV genome: a constant
The biased nucleotide composition of the HIV genome: a constant

... composition has implications for the amino acids that are encoded by the open reading frames (ORFs), both in the requirement of specific tRNA species and in the preference for amino acids encoded by e.g. A-rich codons. Nucleotide composition does obviously affect the secondary and tertiary structure ...
Supplemental Tables
Supplemental Tables

... also posted at the AAA site, were also used in this analysis. The FlyBase inferred cytological map locations were assigned to all of the orthologs called in the four species. These associations were then ordered and sorted according to their scaffold assignments and molecular coordinates for each sp ...
8th grade Chapter 8
8th grade Chapter 8

... and grouped into 23 pairs of chromosomes. Together these are called our genome. B. Within a species (group of related organisms) each organism has the same number of chromosomes. C. However, genome size (the number of chromosomes) changes from one species to the next. D. For example a fruit fly has ...
Schizophrenia genetics: emerging themes for a complex disorder
Schizophrenia genetics: emerging themes for a complex disorder

... loci, we refer to regions of the genome that contains one or more allele that is associated with disorder at a level corresponding to genome-wide significance. However, because of linkage disequilibrium, typically, a region contains many strongly or partially correlated alleles, any of which might be ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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