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Biol 208/308 Quick Program Reference Course Descriptions:
Biol 208/308 Quick Program Reference Course Descriptions:

... BIOL 208 LEC,TUT Analytical Methods in Molecular Biology An introduction to molecular methods used to analyze the structure of genes and genomes, including DNA sequencing, cloning, restriction mapping and bioinformatic tools. Techniques to monitor transcript and protein abundance, protein-protein an ...
Breeding Policy - Selkirk Rex Cat Club
Breeding Policy - Selkirk Rex Cat Club

... founding Selkirks brought in to the country. Over the following two years a further sixteen cats followed ...
X-Chromosome dosage compensation
X-Chromosome dosage compensation

... In numerous organisms, sex is determined by a chromosome counting mechanism that distinguishes one sex chromosome from two. In flies and worms, XX embryos become females (or hermaphrodites), while XO or XY embryos become males (Bridges, 1916; Madl and Herman, 1979; Nigon, 1951). Sex can also be spec ...
Collagens, modifying enzymes and their mutations in humans, flies
Collagens, modifying enzymes and their mutations in humans, flies

... Figure 2. The main steps in the synthesis of a fibril-forming collagen. The polypeptide chains are synthesized on membrane-bound ribosomes and secreted into the lumen of the endoplasmic reticulum, where the main steps in biosynthesis are: (i) cleavage of the signal peptides (not shown); (ii) hydroxy ...
"RNA Interference in Caenorhabditis elegans".
"RNA Interference in Caenorhabditis elegans".

... specified by a total of only 1000 somatic cells. Due to the highly stereotyped celldivision patterns, the origins and fates of each cell in the embryo and adult are known (Sulston and Horvitz, 1977; Sulston et al., 1983). Consequently, perturbations of the developmental program can be traced to cha ...
Epigenetic Regulation ofbdnfGene Transcription in the
Epigenetic Regulation ofbdnfGene Transcription in the

... et al., 2006), a leading candidate cellular mechanism for associative memory formation (Bliss and Collingridge, 1993; Whitlock et al., 2006). Similarly, there is increasing behavioral evidence indicating that bdnf gene expression is induced in the hippocampus after contextual and spatial learning an ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
Pleiotropic effects of the mouse lethal yellow (Ay) mutation

... We have previously described the isolation and structure of cosmid clones that constitute a 60 kb contig containing agouti exons 1B, 1C, 2, 3 and 4 (Miller et al., 1993) (The agouti exon nomenclature used in the present work differs from that used previously; the rationale is summarized in Fig. 1). ...
Inheritance involved in the pathogenesis of idiopathic scoliosis
Inheritance involved in the pathogenesis of idiopathic scoliosis

... idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree construction between human studies, an arbitrary consensus threshold for proband curve magnitude that may obscure true heritability, and the lack of a genetic model. I ...
Creating order from chaos: epigenome dynamics in
Creating order from chaos: epigenome dynamics in

... AT-rich and sometimes prefer to insert into AT-rich regions (Le et al., 2000; Naito et al., ...
Complete genome sequence of the prototype lactic acid bacterium
Complete genome sequence of the prototype lactic acid bacterium

... preceded by an AT-rich region (71%) containing seven DnaA boxes, four on the forward strand and three on the reverse strand. Therefore, the first base pair of dnaA was designated position 1 on the circular chromosome of L. lactis MG1363. The putative terminus is at position 1255251 (Fig. 1). A total ...
GSEA - Bioinformatics Unit
GSEA - Bioinformatics Unit

... The Kolmogorov–Smirnov test is used to determine whether two underlying one-dimensional probability distributions differ, or whether an underlying probability distribution differs from a hypothesized distribution, in either case based on finite samples. ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics

... Variable breakpoints on both genes. Abnormal protein ...
Direct control of shoot meristem activity by a cytokinin
Direct control of shoot meristem activity by a cytokinin

... chromosome 1, in which there were four putative genes (Fig. 2a). Mutations in one of the four predicted genes were found in all six log mutant alleles, whereas no mutation was found in any of the other three predicted genes (Fig. 2b; Supplementary Fig. 1). The mutant phenotype of log-2 was complemen ...
A Pseudomonas syringae pv. tomato DC3000 mutant
A Pseudomonas syringae pv. tomato DC3000 mutant

... 1964; Mysore and Ryu, 2004). Type-II non-host and racespecific resistance against P. syringae often appear similar. When inoculated at a low level, P. syringae strains will grow well initially in plants with either type of resistance, but growth is sustained for several days and necrotic symptoms ar ...
Transcriptional Attenuation
Transcriptional Attenuation

... attenuator, is controlled by a particular metabolic signal. In bacteria, there are many examples of attenuation that differ in the way that termination is made conditional. We have divided them into four classes based on their common features. A single, well-studied example of each class is describe ...
Provisional PDF
Provisional PDF

... losses (Shen et al., 2015). For example, hepatopancreatic necrosis disease (HPND, “shuibiezi” in Chinese), which affects E. sinensis, has been a major problem in the crab-cultivated area of Jiangsu Province since 2015. Crabs with HPND exhibit multiple clinical symptoms, including hepatopancreata tha ...
Emended description of the order Chlamydiales, proposal of
Emended description of the order Chlamydiales, proposal of

... The current taxonomic classification of Chlamydia is based on limited phenotypic, morphologic and genetic criteria. This classification does not take into account recent analysis of the ribosomal operon or recently identified obligately intracellular organisms that have a chlamydia-like developmenta ...
The Parasexual Cycle in Candida albicans Provides an
The Parasexual Cycle in Candida albicans Provides an

... cell fusion. The resulting tetraploid strains can return to the diploid state via a non-meiotic parasexual program of concerted chromosome loss. We used SNP and comparative genome hybridization to analyze the progeny resulting from this parasexual cycle and found a range of genetically diverse strai ...
Forche et al. 2008 PLoS Biology
Forche et al. 2008 PLoS Biology

... cell fusion. The resulting tetraploid strains can return to the diploid state via a non-meiotic parasexual program of concerted chromosome loss. We used SNP and comparative genome hybridization to analyze the progeny resulting from this parasexual cycle and found a range of genetically diverse strai ...
Inference of natural selection on quantitative traits
Inference of natural selection on quantitative traits

... ton 2011b). The time evolution of allele frequencies in a population can be described using stochastic differential equations and the steady state of a population, balancing the forces of selection (increasing the fitness) and random genetic drift (decreasing the fitness), can be determined using me ...
evolution - Santa Fe Institute
evolution - Santa Fe Institute

... Other characters, such as floral symmetry, may be highly conserved among species of a particular clade. While some of the variation may be due to differences in the selective forces acting on the character, the ubiquity of gene interaction and the potential for robust genotypes raises the intriguing ...
Mapping the Horns (Ho) Locus in Sheep: A Further Locus
Mapping the Horns (Ho) Locus in Sheep: A Further Locus

... A second locus is also known to produce horns in sheep (Dry 1955). Unlike the Ho locus, the Halo hair (HH1) locus (COGNOSAG 1989) has a marked effect on fleece characteristics. Sheep carrying the HH1N allele produce a high abundance of halo hair on the backs of young lambs. The adult mature fleece i ...
Common Quantitative Trait Loci for Alcohol
Common Quantitative Trait Loci for Alcohol

... for hypnotic sensitivity and have identified and confirmed significant QTL in a large panel of F2 mice derived from the ISS and ILS inbred strains (Markel et al., 1996). One of the highly significant QTL was for the marker, D2MIT21, located at 80 cM on chromosome 2 (Markel et al., 1996), a locus lin ...
Supplementary Legends - Word file
Supplementary Legends - Word file

... of the C. elegans zygote, and their roles in redundant cleavage plane specification as analysed by asymmetric spindle severing (ASS): Shown are gene names, loci, knockout method and phenotypes after ASS. Gene knockout was performed using established protocols, either by using feeding clones obtained ...
STUDIES OF INHERITANCE IN LOP
STUDIES OF INHERITANCE IN LOP

... on the basis of his studies of quantitative characters in oats and wheat. Since then, numerous studies of quantitative characters in animals and plants have served to establish firmly the multiple factor hypothesis. But no further study has been made of the peculiar ear character found in lop-eared ...
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Genome evolution



Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.
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