DNA Hybridization: A Decade of Molecular Discourse in Hominoid
... and Ahlquist (hereafter referred to as "S/A"). It was the first study using DNA hybridization that presented a complete matrix of distance values based on the average of five or more comparisons for each node, and it was also the first to present molecular evidence for a Pan-Homo clade. Based on the ...
... and Ahlquist (hereafter referred to as "S/A"). It was the first study using DNA hybridization that presented a complete matrix of distance values based on the average of five or more comparisons for each node, and it was also the first to present molecular evidence for a Pan-Homo clade. Based on the ...
biofundamentals - virtual laboratories
... non-random events. These evolutionary mechanisms (which we will discuss in some detail) include the origin of mutations, that is, changes that alter the genetic material (double-stranded deoxyribonucleic acid or DNA) and the effects of these molecular variation on the behavior of the organis(their p ...
... non-random events. These evolutionary mechanisms (which we will discuss in some detail) include the origin of mutations, that is, changes that alter the genetic material (double-stranded deoxyribonucleic acid or DNA) and the effects of these molecular variation on the behavior of the organis(their p ...
Recombination and clonal groupings within Helicobacter pylori from
... bacteria from different continents or that particular alleles are selected for in certain populations. However, a different segment of the vacA gene was found to have recombined freely in bacteria isolated from Canada and South Africa (Suerbaum et al ., 1998). The virulence-associated cagA gene enco ...
... bacteria from different continents or that particular alleles are selected for in certain populations. However, a different segment of the vacA gene was found to have recombined freely in bacteria isolated from Canada and South Africa (Suerbaum et al ., 1998). The virulence-associated cagA gene enco ...
TITLE: The Genetics of the Major
... canine chromosome may permit rapid identification of a candidate gene for HOD disease susceptibility across many breeds. The Weimaraner breed will give us the potential to dissect complex environmental influences from underlying genetic risk factors to determine if there is a common cause for HOD in ...
... canine chromosome may permit rapid identification of a candidate gene for HOD disease susceptibility across many breeds. The Weimaraner breed will give us the potential to dissect complex environmental influences from underlying genetic risk factors to determine if there is a common cause for HOD in ...
PDF - Canine Genetics and Epidemiology
... this has had a detrimental effect on the health and welfare of many pedigree breeds. Indeed studies have empirically determined a large depletion in genetic diversity in some pedigree dogs breeds [1–3], and many breeds do suffer a high burden of genetic disease [4]. Inbreeding is unavoidable in fini ...
... this has had a detrimental effect on the health and welfare of many pedigree breeds. Indeed studies have empirically determined a large depletion in genetic diversity in some pedigree dogs breeds [1–3], and many breeds do suffer a high burden of genetic disease [4]. Inbreeding is unavoidable in fini ...
pdf
... transposition affords an opportunity to seal chromosome breaks. Other possible benefits have not been excluded. Thus the relationship between transposable elements and their hosts may be as much symbiotic as parasitic. Resolving these issues is an interesting challenge for future research. Discovery ...
... transposition affords an opportunity to seal chromosome breaks. Other possible benefits have not been excluded. Thus the relationship between transposable elements and their hosts may be as much symbiotic as parasitic. Resolving these issues is an interesting challenge for future research. Discovery ...
Hybrid Genetic Algorithm for Machine
... respectively. The number of genes in a machine chromosome is equal to the number of machines. The gene value at a particular gene position of a machine chromosome represents the cell number to which the corresponding machine is assigned. Similarly, gene positions from left to right in a component ch ...
... respectively. The number of genes in a machine chromosome is equal to the number of machines. The gene value at a particular gene position of a machine chromosome represents the cell number to which the corresponding machine is assigned. Similarly, gene positions from left to right in a component ch ...
Sarah Pulliam
... longevity in mice. Four different mouse models are genetically engineered for the experiment: control (wild type) mice, mice with a single extra gene-dose of either Arf (s-Arf) or p53 (s-p53), and mice with an extra gene dose of both Arf and p53 (s-Arf/p53) (Blasco et al. 375). The s-Arf/p53 mice wi ...
... longevity in mice. Four different mouse models are genetically engineered for the experiment: control (wild type) mice, mice with a single extra gene-dose of either Arf (s-Arf) or p53 (s-p53), and mice with an extra gene dose of both Arf and p53 (s-Arf/p53) (Blasco et al. 375). The s-Arf/p53 mice wi ...
As a PDF file
... in LAB. The second part describes isolation, cloning and characterization of genes encoding enzymes that are promising for the further development of genetically modified lactic acid bacteria. In the first part, either the ldhD and ldhL genes, or ldhD alone, were inactivated using gene replacement t ...
... in LAB. The second part describes isolation, cloning and characterization of genes encoding enzymes that are promising for the further development of genetically modified lactic acid bacteria. In the first part, either the ldhD and ldhL genes, or ldhD alone, were inactivated using gene replacement t ...
SAB-2010
... its current location in JIC (www.arabidopsis reactome.org) , followed by active curation. • Active curation will be primarily done in collaboration with Nick Provart’s group at Univ. of Toronto. • This is a new International Collaboration ...
... its current location in JIC (www.arabidopsis reactome.org) , followed by active curation. • Active curation will be primarily done in collaboration with Nick Provart’s group at Univ. of Toronto. • This is a new International Collaboration ...
cg12 Expression Is Specifically Linked to Infection of
... nification of the cell walls is a cytological marker of differentiation of nodule cells for bacterial nitrogen fixation (Berg and McDowell 1987), we conclude that the activity of the cg12 promoter is correlated with Frankia infection of the plant cell and slows down when nitrogen fixation starts. In ...
... nification of the cell walls is a cytological marker of differentiation of nodule cells for bacterial nitrogen fixation (Berg and McDowell 1987), we conclude that the activity of the cg12 promoter is correlated with Frankia infection of the plant cell and slows down when nitrogen fixation starts. In ...
Genetic, psychosocial, and demographic factors associated with
... closely to alcohol and cigarette experimentation in adolescents (McGue et al. 2006; Wilkinson et al. 2012), behaviors that have potential long-term consequences for health that are frequently initiated during adolescence and established in young adulthood (Paavola et al. 2004). While genetic risk fa ...
... closely to alcohol and cigarette experimentation in adolescents (McGue et al. 2006; Wilkinson et al. 2012), behaviors that have potential long-term consequences for health that are frequently initiated during adolescence and established in young adulthood (Paavola et al. 2004). While genetic risk fa ...
Complete genome sequence of the rifamycin SV
... found in streptomycetes, this chromosome is circular, particularly similar to that of Saccharopolyspora erythraea and Nocardia farcinica, representing their close relationship in phylogeny and taxonomy. Although the predicted 9 228 protein-coding genes in the A. mediterranei genome shared the greate ...
... found in streptomycetes, this chromosome is circular, particularly similar to that of Saccharopolyspora erythraea and Nocardia farcinica, representing their close relationship in phylogeny and taxonomy. Although the predicted 9 228 protein-coding genes in the A. mediterranei genome shared the greate ...
"Hybrid Incompatibility in Drosophila: An Updated Genetic and
... During the 1990s and the 2000s, several researchers carried out a series of experiments that culminated in the mapping and characterisation of a number of genes that had a significant major effect on interspecies hybrid sterility (Table 1). The paradigmatic example concerns the study of the Odysseus ...
... During the 1990s and the 2000s, several researchers carried out a series of experiments that culminated in the mapping and characterisation of a number of genes that had a significant major effect on interspecies hybrid sterility (Table 1). The paradigmatic example concerns the study of the Odysseus ...
Computational approaches to understanding the genetic
... Type and number of various kinds of human genetic variation. Single nucleotide polymorphisms (SNPs) are the most common, making up about 95% of all variation. In each case, an example modification to the sequence GATTACA is provided. Note that there are many kinds of structural variation, and the ex ...
... Type and number of various kinds of human genetic variation. Single nucleotide polymorphisms (SNPs) are the most common, making up about 95% of all variation. In each case, an example modification to the sequence GATTACA is provided. Note that there are many kinds of structural variation, and the ex ...
Mutations in SIN4 and RGR1 Cause Constitutive Expression of MAL
... Gene disruptions were done by the PCR-based one-step gene replacement method in appropriate strains. The primer pairs used for each different gene disruption were determined on the basis of the sequence of S288C available at the Saccharomyces Genome Database (http://genome-www.stanford.edu/ Saccharo ...
... Gene disruptions were done by the PCR-based one-step gene replacement method in appropriate strains. The primer pairs used for each different gene disruption were determined on the basis of the sequence of S288C available at the Saccharomyces Genome Database (http://genome-www.stanford.edu/ Saccharo ...
Highly precise and developmentally programmed genome
... DSBs to achieve the precise assembly of somatic genes. Careful examination of cleaved IES ends has led to a mechanistic model, in which two DSBs, one at each end, initiate IES excision [11]. Genetic evidence for a crosstalk between ends before DNA cleavage further supported the view that IES ends ar ...
... DSBs to achieve the precise assembly of somatic genes. Careful examination of cleaved IES ends has led to a mechanistic model, in which two DSBs, one at each end, initiate IES excision [11]. Genetic evidence for a crosstalk between ends before DNA cleavage further supported the view that IES ends ar ...
Case-Parent Triads
... ingenious approach requires no controls in the usual sense but relies instead on allele frequencies among diseased persons and their biologic parents. The key observation, made by Rubinstein et al. (1) in 1981, is that alleles associated with a given disease will occur more often in diseased persons ...
... ingenious approach requires no controls in the usual sense but relies instead on allele frequencies among diseased persons and their biologic parents. The key observation, made by Rubinstein et al. (1) in 1981, is that alleles associated with a given disease will occur more often in diseased persons ...
Population structure enhances perspectives on regional
... nesting green turtle in the SWIO, our novel data set was combined with those analysed by Bourjea et al. (2007b; Fig. 1, Table 1). For Farquhar, we combined the samples presented in this study (N=20) with the previous ones (N=7), for a total of 27 samples. We refer in this paper to the Southern Mozam ...
... nesting green turtle in the SWIO, our novel data set was combined with those analysed by Bourjea et al. (2007b; Fig. 1, Table 1). For Farquhar, we combined the samples presented in this study (N=20) with the previous ones (N=7), for a total of 27 samples. We refer in this paper to the Southern Mozam ...
Incomplete penetrance of MHC susceptibility genes
... pairs, sib pairs in general and MHC-identical unrelated individuals. Inheritance patterns in families do not reveal modes of inheritance of incompletely penetrant polygenic MHC-determined traits. A method is proposed to study such traits prospectively in persons presumed to be homozygous, heterozygo ...
... pairs, sib pairs in general and MHC-identical unrelated individuals. Inheritance patterns in families do not reveal modes of inheritance of incompletely penetrant polygenic MHC-determined traits. A method is proposed to study such traits prospectively in persons presumed to be homozygous, heterozygo ...
Accepted Version - CSIRO Research Publications Repository
... Another mutant phenotype seen in the ddm1 background, change of plant structure (short and compact inflorescence with reduced plant height), is bns (BONSAI), which is unstably inherited in the presence of the DDM1 gene. The BNS gene encodes a protein with similarity to the mammalian cell cycle regul ...
... Another mutant phenotype seen in the ddm1 background, change of plant structure (short and compact inflorescence with reduced plant height), is bns (BONSAI), which is unstably inherited in the presence of the DDM1 gene. The BNS gene encodes a protein with similarity to the mammalian cell cycle regul ...
Specific Combinations of Zein Genes and Genetic Backgrounds
... As in O2 lines, in the o2 genotypes the pattern that occurs at maturity is almost identical to the one present in immature seeds at 20 or 25 days after pollination (DAP; Fig. 1B). In any case the zein pattern observed for each line is constant in seeds obtained from field- or greenhouse-grown plants ...
... As in O2 lines, in the o2 genotypes the pattern that occurs at maturity is almost identical to the one present in immature seeds at 20 or 25 days after pollination (DAP; Fig. 1B). In any case the zein pattern observed for each line is constant in seeds obtained from field- or greenhouse-grown plants ...
Analysing complex genetic traits with chromosome
... and select against donor contributions to other regions (speedcongenic breeding). All 21 strains have remained viable and continue to yield heterosomic progeny at the desired frequency. With the most recent generation of breeding, the strains have now produced progeny that have retained the desired ...
... and select against donor contributions to other regions (speedcongenic breeding). All 21 strains have remained viable and continue to yield heterosomic progeny at the desired frequency. With the most recent generation of breeding, the strains have now produced progeny that have retained the desired ...
Information about mosaic Neurofibromatosis type 2
... vestibular schwannoma. Differentiating this diagnosis from either generalised NF2 or mosaic NF2 is clearly important because health monitoring and management will be different to reflect the differing health implications. The next step to clarify the diagnosis is usually to take a blood test to look ...
... vestibular schwannoma. Differentiating this diagnosis from either generalised NF2 or mosaic NF2 is clearly important because health monitoring and management will be different to reflect the differing health implications. The next step to clarify the diagnosis is usually to take a blood test to look ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.