Alfred Henry Sturtevant - National Academy of Sciences
... study of the unstable Bar mutant of Drosophila in order to learn more about the nature of mutations and the mechanisms by which new ones arise. It was known by then that mutations, in the sense of simply inherited changes, could take the form of changes in numbers of chromosomes (such as trisomy or ...
... study of the unstable Bar mutant of Drosophila in order to learn more about the nature of mutations and the mechanisms by which new ones arise. It was known by then that mutations, in the sense of simply inherited changes, could take the form of changes in numbers of chromosomes (such as trisomy or ...
Special Report on Genetics and: Gout 23 Selected Articles From 199
... Cerebrovascular Disease -- Disorders which result in defective brain arteries, including stroke (both hemorrhagic and ischemic). Abstract 2006 Genetically determined gout: characteristics of the course. [Article in Russian] ...
... Cerebrovascular Disease -- Disorders which result in defective brain arteries, including stroke (both hemorrhagic and ischemic). Abstract 2006 Genetically determined gout: characteristics of the course. [Article in Russian] ...
DNA-Based Methods for the Identification of Commercial Fish and
... a number of advantages over protein-based methods, including increased specificity, sensitivity, and reliable performance with highly processed samples (Lenstra 2003). Although DNA molecules can degrade during processing, they are more thermostable than proteins: DNA fragments as long as 300 bp can ...
... a number of advantages over protein-based methods, including increased specificity, sensitivity, and reliable performance with highly processed samples (Lenstra 2003). Although DNA molecules can degrade during processing, they are more thermostable than proteins: DNA fragments as long as 300 bp can ...
Discover Debate Decide_exploring ethical
... Designer babies: Popular press term for babies who have been selected for birth on the basis of their genetics. Double helix: The coiled structure of double-stranded DNA. DNA: Deoxyribonucleic acid. The chemical which carries our genetic code. DNA is divided into genes. Dominant Allele: Expressed in ...
... Designer babies: Popular press term for babies who have been selected for birth on the basis of their genetics. Double helix: The coiled structure of double-stranded DNA. DNA: Deoxyribonucleic acid. The chemical which carries our genetic code. DNA is divided into genes. Dominant Allele: Expressed in ...
The genetic basis of panic and phobic anxiety disorders
... the alleles studied include variants that are either directly related to the phenotype or strongly correlated with (i.e., in linkage disequilibrium with) such causal variants. Two approaches to association analysis are now feasible: (1) candidate gene studies, in which loci hypothesized to be causal ...
... the alleles studied include variants that are either directly related to the phenotype or strongly correlated with (i.e., in linkage disequilibrium with) such causal variants. Two approaches to association analysis are now feasible: (1) candidate gene studies, in which loci hypothesized to be causal ...
Case Report Section
... and HLA DR, suggesting that the leukemic cells have an immature myeloid stem cell origin (Harada et al., 1995; Ma et al., 1997; Hamaguchi et al., 1999). Of the reported t(4;12) AML cases; seven were characterized as AML-M0 and four AML-M1. Previous reports suggest that less than 50% of cases achieve ...
... and HLA DR, suggesting that the leukemic cells have an immature myeloid stem cell origin (Harada et al., 1995; Ma et al., 1997; Hamaguchi et al., 1999). Of the reported t(4;12) AML cases; seven were characterized as AML-M0 and four AML-M1. Previous reports suggest that less than 50% of cases achieve ...
Gentile, Margaret: Computational Methods for the Design of PCR Primers for the Amplification of functional Markers from Environmental Samples
... and then design the primers within those regions. Previously, we discussed two attempts at designing primers in conserved regions (Braker et al, 1998 and Hallin and Lindgren, 1999). However, both of these attempts neglected to deal with the challenges which complicate the search for so called “conse ...
... and then design the primers within those regions. Previously, we discussed two attempts at designing primers in conserved regions (Braker et al, 1998 and Hallin and Lindgren, 1999). However, both of these attempts neglected to deal with the challenges which complicate the search for so called “conse ...
Gene Section SIL (SCL/TAL1 interrupting locus) Atlas of Genetics and Cytogenetics
... SIL is an immediate early gene, with ubiquitous expression in proliferating cells and during early embryonic development. SIL protein levels peak during mitosis and are degraded on transition to G1. SIL is phosphorylated in mitosis. It is expressed in multiple cancers. In lung cancer its expression ...
... SIL is an immediate early gene, with ubiquitous expression in proliferating cells and during early embryonic development. SIL protein levels peak during mitosis and are degraded on transition to G1. SIL is phosphorylated in mitosis. It is expressed in multiple cancers. In lung cancer its expression ...
The molecular genetics of head development in Drosophila
... (Turner and Mahowald, 1977). Much of our understanding of the process of head formation described below stems from the detailed scanning electron microscopy (SEM) studies of Turner and Mahowald (1979). Initially, the 'germ band' of the embryo is fully extended and segmental furrows are clearly visib ...
... (Turner and Mahowald, 1977). Much of our understanding of the process of head formation described below stems from the detailed scanning electron microscopy (SEM) studies of Turner and Mahowald (1979). Initially, the 'germ band' of the embryo is fully extended and segmental furrows are clearly visib ...
The Coat of Many Colors
... inserted into the merle gene contains a long string of “A’s” that “turn off” the SILV gene so that it cannot produce the SILV protein helping to form melanosomes. It turns out that mutations occur in this string of “A’s”quite often as cells divide, decreasing the string’s length. The result is that ...
... inserted into the merle gene contains a long string of “A’s” that “turn off” the SILV gene so that it cannot produce the SILV protein helping to form melanosomes. It turns out that mutations occur in this string of “A’s”quite often as cells divide, decreasing the string’s length. The result is that ...
structural optimization with genetic algorithms and particle swarm
... developed for MATLAB and can be used both for actual optimization problems as well as for research. Its flexible structure allows the testing of new genetic algorithm operators and procedures. Although there are some efforts in this direction, more software libraries targeted for the.NET framework w ...
... developed for MATLAB and can be used both for actual optimization problems as well as for research. Its flexible structure allows the testing of new genetic algorithm operators and procedures. Although there are some efforts in this direction, more software libraries targeted for the.NET framework w ...
1. Assortative mating— a. affects genotype frequencies expected
... Genetic drift can be generally thought of as changes in allele frequencies and even loss of alleles entirely due to sampling of alleles by random processes, and is exacerbated by small population size. Founder effects are essentially the same process, but occur when new populations are found by just ...
... Genetic drift can be generally thought of as changes in allele frequencies and even loss of alleles entirely due to sampling of alleles by random processes, and is exacerbated by small population size. Founder effects are essentially the same process, but occur when new populations are found by just ...
Package `rDNA`
... A duplicate statement is a statement with the same person, organization, category and agreement pattern as another statement. By default, a duplicate statement is omitted if it is found within the same article (option article). Other options are month (i.e., duplicate statements are omitted if they ...
... A duplicate statement is a statement with the same person, organization, category and agreement pattern as another statement. By default, a duplicate statement is omitted if it is found within the same article (option article). Other options are month (i.e., duplicate statements are omitted if they ...
Finland
... tion within the stand. In the management of gene reserve forests, the principal aim is to ensure abundant regeneration and a wide gene pool. In general, the management does not differ significantly from normal forestry practices used in Finland. Most important aspect is to support natural regenerati ...
... tion within the stand. In the management of gene reserve forests, the principal aim is to ensure abundant regeneration and a wide gene pool. In general, the management does not differ significantly from normal forestry practices used in Finland. Most important aspect is to support natural regenerati ...
Ch. 2 OLC questions
... Genetic drift can be generally thought of as changes in allele frequencies and even loss of alleles entirely due to sampling of alleles by random processes, and is exacerbated by small population size. Founder effects are essentially the same process, but occur when new populations are found by just ...
... Genetic drift can be generally thought of as changes in allele frequencies and even loss of alleles entirely due to sampling of alleles by random processes, and is exacerbated by small population size. Founder effects are essentially the same process, but occur when new populations are found by just ...
genes is conserved among species related to
... possesses two S-protein-encoding genes, one of which is silent, on a chromosomal segment of 6 kb. The 5-protein-encoding gene in the expression site can be exchanged for the silent S-protein-encoding gene by inversion of t h i s slp segment. In this study the presence of S-protein and corresponding ...
... possesses two S-protein-encoding genes, one of which is silent, on a chromosomal segment of 6 kb. The 5-protein-encoding gene in the expression site can be exchanged for the silent S-protein-encoding gene by inversion of t h i s slp segment. In this study the presence of S-protein and corresponding ...
v2 PEBiosystems News 2 01/00
... The ABI PRISM 3100 and the 3100-Avant Genetic Analyzers include patented technology licensed from Hitachi, Ltd. as part of a strategic partnership between Applied Biosystems and Hitachi, Ltd., as well as patented technology of Applied Biosystems. The Applied Biosystems 3730 and 3730xl DNA Analyzers ...
... The ABI PRISM 3100 and the 3100-Avant Genetic Analyzers include patented technology licensed from Hitachi, Ltd. as part of a strategic partnership between Applied Biosystems and Hitachi, Ltd., as well as patented technology of Applied Biosystems. The Applied Biosystems 3730 and 3730xl DNA Analyzers ...
Comparison of real-time PCR with SYBR Green I or
... when bound to double-stranded DNA, while being otherwise virtually non-fluorescent. SYBR Green I lacks the specificity of the TaqMan assay, where the fluorescent signal is derived from a specific probe. However, SYBR Green I can be applied to the fluorescent monitoring of any amplification reaction, ...
... when bound to double-stranded DNA, while being otherwise virtually non-fluorescent. SYBR Green I lacks the specificity of the TaqMan assay, where the fluorescent signal is derived from a specific probe. However, SYBR Green I can be applied to the fluorescent monitoring of any amplification reaction, ...
Winter oilseed rape
... inhibiting an enzyme in the plant which causes levels of ammonia to rise and the plant to die. A bacterial gene, which produces an enzyme that detoxifies the herbicide, is transferred into the GM oilseed rape so that the crop is not affected. Another gene to switch on the tolerance gene is also tran ...
... inhibiting an enzyme in the plant which causes levels of ammonia to rise and the plant to die. A bacterial gene, which produces an enzyme that detoxifies the herbicide, is transferred into the GM oilseed rape so that the crop is not affected. Another gene to switch on the tolerance gene is also tran ...
You`re one in a googol: optimizing genes for protein expression
... more attention, however, is the treatment of coding sequences. As in biotechnology, these are at the centre of synthetic biology: it is proteins that will catalyse the reactions in a novel metabolic pathway or be the signal transducers or the new biomaterials. There is an implicit assumption that, b ...
... more attention, however, is the treatment of coding sequences. As in biotechnology, these are at the centre of synthetic biology: it is proteins that will catalyse the reactions in a novel metabolic pathway or be the signal transducers or the new biomaterials. There is an implicit assumption that, b ...
Aromatic Amino Acid Hydroxylase Genes and
... mutation, would be necessary to determine whether there is an association between PAH genotype and psychiatric phenotype. In this study no sequence variants were observed in the cofactor binding regions of the TH or TPH gene. This may be due to ethnic differences in mutation frequency because previo ...
... mutation, would be necessary to determine whether there is an association between PAH genotype and psychiatric phenotype. In this study no sequence variants were observed in the cofactor binding regions of the TH or TPH gene. This may be due to ethnic differences in mutation frequency because previo ...
Genetic screening of gamete donors: ethical issues
... ,0.2%, research has shown subfertile men to be at a 8–10 times higher risk of unsuspected chromosomal abnormalities (Van Assche et al., 1996; Chandley, 1998). This is why in assisted reproduction routine karyotyping of men with a sperm concentration ,10 million/ml has been recommended (McLachlan and ...
... ,0.2%, research has shown subfertile men to be at a 8–10 times higher risk of unsuspected chromosomal abnormalities (Van Assche et al., 1996; Chandley, 1998). This is why in assisted reproduction routine karyotyping of men with a sperm concentration ,10 million/ml has been recommended (McLachlan and ...
Ch 14 - Narragansett Pier School
... whole, not a reductionist view of single genes acting in isolation ...
... whole, not a reductionist view of single genes acting in isolation ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.