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Dallas ACIM June 2013
Dallas ACIM June 2013

... exaggerated synthesis of inflammatory cytokines and other mediators in the brain, which in turn influence behavior. These interactions suggest that systemic infections, or indeed any systemic ...
Disorders of the Immune System and Vaccination
Disorders of the Immune System and Vaccination

... – All of a sudden the blood vessel wall has an unfamiliar protein group attached to it and the body mounts an immune response to get rid of it. – Complement and other inflammatory cells are activated that cause damage to surrounding tissues as they try to remove the deposited immune complex. ...
Degree of burns
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... Low blood volume, oliguria Hyponatremia K – damaged cells release K ...
PPoint - Doctor of the Future
PPoint - Doctor of the Future

... parts of the CNS affected Typical onset in adults 20-55 years old Multi-focal inflammatory demyelination of axons, with only minimal axonal damage within the brain, spinal cord and optic nerves Primary progressive MS – progressive worsening from the first onset Secondary progressive MS – progressive ...
Poster Anna 2009
Poster Anna 2009

... “mistake of evolution” that created the conditions for human diseases related to gluten exposure. ...
PowerPoint - New Page 1
PowerPoint - New Page 1

... despite presence of intact axons and GalC+ve cells in the same lesion area. • GalC +ve cells do not appear to mature into MOG +ve cells to form new myelin – Cells appear quiescent. Die before they can mature? ...
Biochemistry & Immunology 2016 APRIL
Biochemistry & Immunology 2016 APRIL

... medicine. Traditional approaches to vaccine development have failed to develop an effective weapon against MRSA, methicillin resistant S. aureus, a major cause of healthcare-associated infections and mortality. Eight promising candidate vaccines have failed in clinical trials, despite showing promis ...
Unit 4 Mind Maps
Unit 4 Mind Maps

... activated T Lymphocytes respond to pathogens Describe importance of memory B lymphocytes in the secondary response ...
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as a PDF

... cases with progressive disease course and severe neurological de®cit axonal destruction and loss can be profound, in some cases affecting more than 80% of the axonal population in the plaques.2 Furthermore, the degree of axonal loss and atrophy more closely correlates with permanent clinical de®cit ...
Provisional programme
Provisional programme

... neurodegenerative disorders (hyperphosphorylated tau, amyloid plaques and misfolded synuclein) is paralleled by an increase in circulatory inflammatory molecules (cytokines, chemokines, etc), by a systemic, intrathecal & intracerebral immune dysregulation, a neuroinflammation and oxydative stress. I ...
Hemorrhagic diseases
Hemorrhagic diseases

...  It is also known as Bateman purpura, after British dermatology pioneer Thomas Bateman, who first described it in 1818. ...
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Vasculitis

... Therapy • Daily doses of another immunosuppressant, azathioprine, then follow for a year or more. • This standard therapy usually clears the vasculitis, but relapse is common. • In addition, this treatment suppresses the immune system in a non-specific way and has potentially severe side effects. • ...
DCVax-Prostate
DCVax-Prostate

... copies circulated, or disclosed to another party, without the prior written consent of Northwest Biotherapeutics (NWBT) are strictly prohibited. Information and opinions presented in this report have been obtained or derived from sources believed to be reliable, but NWBT makes no representation as t ...
Kynurenines and Multiple Sclerosis: The Dialogue between the
Kynurenines and Multiple Sclerosis: The Dialogue between the

... The inflammation in MS may trigger a pathogenetic cascade of events leading to neurodegeneration, amplified by mechanisms related to brain aging and an accumulated disease burden. The factors causing this neurodegeneration include chronic oxidative injury, microglia activation, accumulation of mitoc ...
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Study shows that inhaling a common manufacturing material could

... researchers from both institutions have found that inhalation of carbon nanotubes causes inflammation in the brain. Previous research has shown that chronic neuroinflammation is linked to neurological diseases such as Alzheimer's, dementia and hemorrhagic strokes. "Inhalation-induced neuroinflammati ...
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... Many of the 420 medicines in the pipeline include treatments that explore new pathways and scientific approaches to treat these complex disorders. Examples of innovative treatments in development include: • A monoclonal antibody in development for the prevention of migraine binds to and inhibits th ...
Downloadable PPT - Research To Practice
Downloadable PPT - Research To Practice

... PD-L2. Also, much cross talk occurs between Reed-Sternberg cells and cells in the surrounding inflammatory infiltrate, which makes HL a tumor that is amenable to immunotherapy. Pembrolizumab, like nivolumab, causes dual blockade of both PD-L1 and PD-L2. An interesting aspect of our study is that of ...
Ms. Costello`s and Dr. Gocke`s PowerPoint slides
Ms. Costello`s and Dr. Gocke`s PowerPoint slides

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Ulcerative Colitis : UPDATED
Ulcerative Colitis : UPDATED

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Mycobacterium tuberculosis

... an acute inflammatory reaction with edema fluid; polymorphonuclear leukocytes; and, later, monocytes accumulate around the tubercle bacilli. (ii) Productive lesion (granuloma and tubercle formation). It is consists of three zones: (1) a central area of large, multinucleated giant cells containing tu ...
Our Behind the Scenes Partner:
Our Behind the Scenes Partner:

... of the 5 immunoglobulins on the patient’s response to an infection • The attendee will be able to list at least 3 tests, not performed in the microbiology lab, used to aid in the diagnosing of infections/infectious diseases • The attendee will be able to discuss the implications of various types of ...
Inflammation
Inflammation

... Phagocytosis- leukocytes engulf and destroy bacteria and other material Natural Killer Cells- type of leukocyte that recognizes body cells with abnormal membranes Fever- sign the body is defending itself; phagocytes find and destroy foreign invaders; releasing substances that raise the body temp Int ...
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Pathophysiology of multiple sclerosis

Multiple sclerosis (MS) is a condition where the CNS of a person present a special kind of distributed glial scars (sclerosis) which are a remaining of a previous inflammatory demyelination. MS pathophysiology is complex and still under investigation and there is no agreement about its scope. Some authors consider it a pathological entity, while others consider it a clinical entity. From a pathological point of view, the demyelinating lesions can be classified as encephalomyelitis, and sometimes the disease is known as encephalomyelitis disseminata.There are two phases for how an unknown underlying condition may cause damage in MS: First some MRI-abnormal areas with hidden damage appear in the brain and spine (NAWM, NAGM, DAWM). Second, there are leaks in the blood–brain barrier where immune cells infiltrate causing the known demyelination and axon destruction. Some clusters of activated microglia, transection of axons and myelin degeneration is present before the BBB breaks down and the immune attack beginsPathophysiology is a convergence of pathology with physiology. Pathology is the medical discipline that describes conditions typically observed during a disease state; whereas physiology is the biological discipline that describes processes or mechanisms operating within an organism. Referring to MS, the physiology refers to the different processes that lead to the development of the lesions and the pathology refers to the condition associated with the lesions.
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