Chapter 9
... Regulation of eIF4E: Growth factors activate protein kinases that phosphorylate regulatory proteins (eIF4E binding proteins, or 4E-BPs). In the absence of growth factors, the nonphosphorylated 4E-BPs bind to eIF4E and inhibit translation. ...
... Regulation of eIF4E: Growth factors activate protein kinases that phosphorylate regulatory proteins (eIF4E binding proteins, or 4E-BPs). In the absence of growth factors, the nonphosphorylated 4E-BPs bind to eIF4E and inhibit translation. ...
Detergent-resistant plasma membrane proteome to elucidate
... The plasma membrane (PM) is a typical cellular membrane with selective permeability and surrounds all organelles and cellular substances. Therefore, the PM is thought to be the most important cellular membrane due to relationships to various important cellular processes including cell division, diff ...
... The plasma membrane (PM) is a typical cellular membrane with selective permeability and surrounds all organelles and cellular substances. Therefore, the PM is thought to be the most important cellular membrane due to relationships to various important cellular processes including cell division, diff ...
Article - Saha Institute of Nuclear Physics
... apart from auxin (gibberelic acid, cytokinin, sugars, brassinosteroids), with interlinked signaling pathways. ...
... apart from auxin (gibberelic acid, cytokinin, sugars, brassinosteroids), with interlinked signaling pathways. ...
The Vacuolar Proton-Cation Exchanger EcNHX1
... wall-localized proteins, and other defense constituents (Tsunezuka et al., 2005; Truman et al., 2007). This complexity is based on widely ramified signal cascades that use ubiquitous intermediates such as jasmonates (Blechert et al., 1995; Memelink et al., 2001), calcium ions, and salicylates and are ...
... wall-localized proteins, and other defense constituents (Tsunezuka et al., 2005; Truman et al., 2007). This complexity is based on widely ramified signal cascades that use ubiquitous intermediates such as jasmonates (Blechert et al., 1995; Memelink et al., 2001), calcium ions, and salicylates and are ...
Sickle cell anaemia
... The abnormalities of the gene may result from substitution of single amino acid like sickle cell anaemia or decrease synthesis of the whole globin chain (thalassaemia) ...
... The abnormalities of the gene may result from substitution of single amino acid like sickle cell anaemia or decrease synthesis of the whole globin chain (thalassaemia) ...
Probing protein function by chemical modification
... widely used in tissue immunostaining via the conjugation of organic dyes to antibodies. Recent progress in bioconjugation techniques has expanded the range of modification residues to include tryptophan and tyrosine [46–49]. However, these residue-specific bioconjugation approaches are not selective ...
... widely used in tissue immunostaining via the conjugation of organic dyes to antibodies. Recent progress in bioconjugation techniques has expanded the range of modification residues to include tryptophan and tyrosine [46–49]. However, these residue-specific bioconjugation approaches are not selective ...
Metabol Nutri-ClinEnz Med 2_6 Nov 2012
... a) the rate of release from damaged cells which, in turn, depends on the rate at which damage is occurring; b) the extent of cell damage. ...
... a) the rate of release from damaged cells which, in turn, depends on the rate at which damage is occurring; b) the extent of cell damage. ...
Corticotropin-Releasing Factor Receptor Antagonists: Potential
... using both receptor autoradiography and in situ hybridization studies. Using these techniques, CRF binding sites and CRF receptor mRNA have been localized in anatomically and physiologically relevant areas. For example, the highest density of CRF1 receptors exists in the pituitary gland, where CRF1 ...
... using both receptor autoradiography and in situ hybridization studies. Using these techniques, CRF binding sites and CRF receptor mRNA have been localized in anatomically and physiologically relevant areas. For example, the highest density of CRF1 receptors exists in the pituitary gland, where CRF1 ...
Functions and Mechanisms of Fibroblast Growth Factor (FGF
... presumably more than 70 FGFR/FGF combinations are generated by four FGFRs and 22 FGF ligands, respectively; alternative mRNA splicing increases the FGFR repertoire from four to seven proteins [2,3]. Moreover, from the possible FGFR/FGF combinations, human cells may utilize more than one at the same ...
... presumably more than 70 FGFR/FGF combinations are generated by four FGFRs and 22 FGF ligands, respectively; alternative mRNA splicing increases the FGFR repertoire from four to seven proteins [2,3]. Moreover, from the possible FGFR/FGF combinations, human cells may utilize more than one at the same ...
RiceRBP: a resource for experimentally identified RNA
... 2009; Wienkoop et al., 2010; Agrawal and Rakwal, 2011). They have also been used to explore protein interactions with other proteins, complexes and particular affinity matrices, which is ultimately important for understanding systems biology (Baginsky, 2009). The use of affinity purification techniques ...
... 2009; Wienkoop et al., 2010; Agrawal and Rakwal, 2011). They have also been used to explore protein interactions with other proteins, complexes and particular affinity matrices, which is ultimately important for understanding systems biology (Baginsky, 2009). The use of affinity purification techniques ...
Tonic and burst firing: dual modes of
... relay cells of lateral geniculate nucleus of the cat, recorded intracellularly from an in vitro slice preparation. (a),(b) Voltage dependency of the LTS. Responses to the same depolarizing current pulse delivered intracellularly are shown, but from two different initial holding potentials. When the ...
... relay cells of lateral geniculate nucleus of the cat, recorded intracellularly from an in vitro slice preparation. (a),(b) Voltage dependency of the LTS. Responses to the same depolarizing current pulse delivered intracellularly are shown, but from two different initial holding potentials. When the ...
Protein Nanocages - Nanyang Technological University
... into the vault lumen is facilitated by attachment to a protein fragment called INT. The INT binds specifically to the internal surface of the vault through protein-protein interactions and acts as a shuttle to ferry the macromolecule cargos into the vault.[7] Towards applications in targeted deliver ...
... into the vault lumen is facilitated by attachment to a protein fragment called INT. The INT binds specifically to the internal surface of the vault through protein-protein interactions and acts as a shuttle to ferry the macromolecule cargos into the vault.[7] Towards applications in targeted deliver ...
The Tell-Tale Heart (Now, Optically Mapped)
... the neighboring, well-coupled unexcited tissue downstream holds their membrane potential polarized. It is known that propagation from a small group of cells (source) into a large group of well-coupled cells (sink) has a low safety factor and is likely to fail. In this scenario, decreasing cellular c ...
... the neighboring, well-coupled unexcited tissue downstream holds their membrane potential polarized. It is known that propagation from a small group of cells (source) into a large group of well-coupled cells (sink) has a low safety factor and is likely to fail. In this scenario, decreasing cellular c ...
Bio-ultrasonics Group
... as an aggregate with a diameter of 1 mm contains approximately 5,000 cells. The structure of the aggregate, the outcome of cell-cell interactions in a suspended aggregate and their consequences for cell behaviour have been shown not to be compromised by or dependent on the physical environment of t ...
... as an aggregate with a diameter of 1 mm contains approximately 5,000 cells. The structure of the aggregate, the outcome of cell-cell interactions in a suspended aggregate and their consequences for cell behaviour have been shown not to be compromised by or dependent on the physical environment of t ...
Muscle
... Ca2+ released from the sarcoplasmic reticulum binds to Troponin C on actin filaments, which subsequently leads to the troponin complex being physically moved aside to uncover cross-bridge binding sites on the actin filament. ...
... Ca2+ released from the sarcoplasmic reticulum binds to Troponin C on actin filaments, which subsequently leads to the troponin complex being physically moved aside to uncover cross-bridge binding sites on the actin filament. ...
Proposal - people.vcu.edu
... Keratin is a vital structural component of the skin that helps to maintain tissue integrity (Keratin, 2016). The goal of this experiment is to determine how disrupting desmoplakin structure may affect its linkage to keratin, and in turn affect the differentiation of the epidermal cells during prenat ...
... Keratin is a vital structural component of the skin that helps to maintain tissue integrity (Keratin, 2016). The goal of this experiment is to determine how disrupting desmoplakin structure may affect its linkage to keratin, and in turn affect the differentiation of the epidermal cells during prenat ...
Dynamics of Ultrastructural Characters of Drosophyllum lusitanicum
... the surface of the vesicle membrane. In sectional views the lattice appears as a series of short spikes radiating from the membrane (Scales et al., 2000). The role of the coat is assumed to be involved in the generation of a mechanical force required to form an evagination of the TGN membrane and th ...
... the surface of the vesicle membrane. In sectional views the lattice appears as a series of short spikes radiating from the membrane (Scales et al., 2000). The role of the coat is assumed to be involved in the generation of a mechanical force required to form an evagination of the TGN membrane and th ...
Request pdf
... T o be regarded as specialized types of nerve cells are the receptor cells that are found at the first stage of any sensory system. T h e receptor can be defined as a neuron in which the generator potential is produced not by synaptic action but by particular environmental stimuli such as pressure, ...
... T o be regarded as specialized types of nerve cells are the receptor cells that are found at the first stage of any sensory system. T h e receptor can be defined as a neuron in which the generator potential is produced not by synaptic action but by particular environmental stimuli such as pressure, ...
AutoMotif server: prediction of single residue post-translational
... the LFM. The negative instances were chosen randomly from those that do not include experimentally verified PTM of any type. These two datasets (positive and negative instances) were projected as sets of points in a multidimensional space (http://automotif.bioinfo.pl/embedding.htm). The SVM (Yu-Dong ...
... the LFM. The negative instances were chosen randomly from those that do not include experimentally verified PTM of any type. These two datasets (positive and negative instances) were projected as sets of points in a multidimensional space (http://automotif.bioinfo.pl/embedding.htm). The SVM (Yu-Dong ...
Re-identification of the N-terminal amino acid residue and its
... and formylation (Stock et al. 1987). Most N-terminal methylated proteins, such as ribosomes, nucleosomes, pilins and flagella, are found to have large macromolecular structures. A number of abundant intracellular proteins including calmodulin, actin, myosin and some nuclear proteins are also known t ...
... and formylation (Stock et al. 1987). Most N-terminal methylated proteins, such as ribosomes, nucleosomes, pilins and flagella, are found to have large macromolecular structures. A number of abundant intracellular proteins including calmodulin, actin, myosin and some nuclear proteins are also known t ...
Chemistry of Life
... 1. What are the 4 major macromolecules? 2. A short polymer and a monomer are linked, what is the by-product and term for this process? 3. How many molecules of water are needed to completely hydrolyze a polymer that is ten monomers long? 4. Why are human sex hormones considered lipids? 5. Identify t ...
... 1. What are the 4 major macromolecules? 2. A short polymer and a monomer are linked, what is the by-product and term for this process? 3. How many molecules of water are needed to completely hydrolyze a polymer that is ten monomers long? 4. Why are human sex hormones considered lipids? 5. Identify t ...
A Novel Temporal Expression Pattern of Three C
... to that protein (Fig lC, top panel). These extracts were also analyzed for C/EBPP and C/EBPG using antisera raised against peptides specific for those proteins (Fig lC, middle panels). For comparison, extracts from an equivalent number of induced 3T3-Ll preadipocytes were also analyzed. Again, C/EBP ...
... to that protein (Fig lC, top panel). These extracts were also analyzed for C/EBPP and C/EBPG using antisera raised against peptides specific for those proteins (Fig lC, middle panels). For comparison, extracts from an equivalent number of induced 3T3-Ll preadipocytes were also analyzed. Again, C/EBP ...
Polo kinase and progression through M phase in Drosophila
... associated with kinetochores and prior to cytokinesis with the mid-part of the central spindle, a characteristic structure that forms in late anaphase and that is essential for cytokinesis. This dynamic pattern of localization led to an expectation that there would be multiple substrates for the kin ...
... associated with kinetochores and prior to cytokinesis with the mid-part of the central spindle, a characteristic structure that forms in late anaphase and that is essential for cytokinesis. This dynamic pattern of localization led to an expectation that there would be multiple substrates for the kin ...
Nuclear Dynamics during Plant Innate Immunity1
... pore complexes (NPCs), which are composed of nucleoporins, and depends on import and export receptors, importins and exportins that respectively recognize nuclear localization signals (NLSs) and nuclear export signals on cargo proteins (Meier and Brkljacic, 2009). The Ras-related nuclear (Ran) prote ...
... pore complexes (NPCs), which are composed of nucleoporins, and depends on import and export receptors, importins and exportins that respectively recognize nuclear localization signals (NLSs) and nuclear export signals on cargo proteins (Meier and Brkljacic, 2009). The Ras-related nuclear (Ran) prote ...
UCLA Bioinformatics - Cal State LA
... Why glutaredoxin-like protein? • Only present among hyperthermophiles. • Operates in thiol-disulfide reaction via CXXC motif which either form a disulfide (oxidized form) or a dithiol (reduced form). • Requires for many functions including electron and proton transport to essential enzymes like rib ...
... Why glutaredoxin-like protein? • Only present among hyperthermophiles. • Operates in thiol-disulfide reaction via CXXC motif which either form a disulfide (oxidized form) or a dithiol (reduced form). • Requires for many functions including electron and proton transport to essential enzymes like rib ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.