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Tumor Necrosis Factor-related Apoptosis
Tumor Necrosis Factor-related Apoptosis

... polypeptide in turn recruits procaspases-8 and -10 to the receptor complex through homotypic interactions involving death effecter domains in Fas-associated protein with death domain and these two apical caspases (4). The resulting activation of the bound caspases is essential for TRAIL-induced apop ...
Cell shape changes during gastrulation in
Cell shape changes during gastrulation in

... been studied in many organisms and various models have been proposed to explain the mechanics of cell and epithelial shape changes, but the molecular mechanisms of the processes are not understood. Molecules that are likely to play important roles in shape changes have been identified and analysed b ...
Identification of Amino Acid Residues within GABAA Receptor
Identification of Amino Acid Residues within GABAA Receptor

... expression of homomeric b subunits. Live A293 cells were labeled by immunofluorescence using FL AG antibody followed by an Alexa 488-conjugated secondary antibody and analyzed by FACS. Figure 4 A shows typical results for mock-transfected A293 cells or cells expressing (FL AG)b2 or (FL AG)b3. E xpre ...
Identification of a Gene Required for Gliding Motility in Myxococcus
Identification of a Gene Required for Gliding Motility in Myxococcus

... that the agiA mutant is defective in A-motility. The agiA mutant, KYC473, was unable to glide individually when the cells were isolated from other cells, but they were gliding normally in a swarm of cells, indicating that S-motility of the mutant was intact (agiA- S ). This suggests that the agiA mu ...
Dynamic Localization of Rop GTPases to the
Dynamic Localization of Rop GTPases to the

... members of the pea Rop family. Using frozen thin sections stained with the primary antibody and alkaline phosphatase-conjugated second antibodies, we found that Rop is preferentially localized to tapetal cells, microsporogenic cells, and microspores in the anther (see below). To analyze the subcellu ...
Plant Cell Walls: Basics of Structure, Chemistry, Accessibility and the
Plant Cell Walls: Basics of Structure, Chemistry, Accessibility and the

... larger and longer fibrils [9]. The cellulose microfibrils are hydrophobic and can be highly crystalline, features that contribute greatly to the recalcitrance of biomass. For example, the 100 crystal face of a microfibril is more hydrophobic than the other faces and selectively binds the CBD (cellul ...
Angiotensin-Induced Desensitization of the Phosphoinositide
Angiotensin-Induced Desensitization of the Phosphoinositide

... capacity were assessed in the following manner. After these treatments, cells were washed once with 0.3 ml of ice-cold 50 mM glycine and 150 mM NaCl, pH 3.0, and were incubated in the same solution for 10 minutes at 4°C. Pilot experiments, in which cardiac cultures were incubated with 1'I-Ang II, re ...
The Evolution of Membranes - University of Guelph Physics
The Evolution of Membranes - University of Guelph Physics

... genes. The genetic code controls the synthesis of proteins, some of which act as enzymes for the synthesis or modification of other molecules. The physical properties are governed by the structures formed when these molecules aggregate in a manner dictated by the normal laws of physics and physical ...
Page 07-LS1-1. Conduct an investigation to provide evidence that
Page 07-LS1-1. Conduct an investigation to provide evidence that

... https://www.glbrc.org/sites/default/files/file-upload/GLBRC-NGSS-Standards.pdf Scroll to standard Lessons for all standards https://www.opened.com/search?category=from-molecules-to-organisms-structuresand-processes-6-8&grade_group=middle-school-lifesciences&license=free&offset=0&standard=MS.LS1.6&st ...
Klebsiella pneumoniae survives within macrophages by
Klebsiella pneumoniae survives within macrophages by

... The Research Portal is Queen's institutional repository that provides access to Queen's research output. Every effort has been made to ensure that content in the Research Portal does not infringe any person's rights, or applicable UK laws. If you discover content in the Research Portal that you beli ...
NAME: IHAZA BLESSING DEPT: ANATOMY COURSE: HISTOLOGY
NAME: IHAZA BLESSING DEPT: ANATOMY COURSE: HISTOLOGY

... central nervous system as well as by receiving innervation from peripheral plexus or endocrine (hormonal) activation. Striated or skeletal muscle only contracts voluntarily, upon influence of the central nervous system. Reflexes are a form of non-conscious activation of skeletal muscles, but nonethe ...
Cell crawling mediates collective cell migration to
Cell crawling mediates collective cell migration to

... area A over the contour length of the interface p normalized by half the instantaneous radius R. For a very rough interface, α ∼ 0, whereas α ∼ 1 for a perfectly circular hole. We indeed observed a decrease of this parameter α with time from 1 (at t = 0) down to approximately 0.6 as the boundary bec ...
Break of symmetry in regenerating tobacco protoplasts is
Break of symmetry in regenerating tobacco protoplasts is

... cell-wall reformation, the cells could be clearly assigned to one of five stages schematically represented in Figure 1. Stage 1, prevailing at the end of digestion (defined as t ¼ 0), comprised round, completely symmetrical protoplasts lacking any indications for axis or polarity. The nucleus is mostl ...
The use of yeast inoculation in fermentation for port production
The use of yeast inoculation in fermentation for port production

... fermentations, referred to as A,B,C&D, corresponding to the media used in the preparation of the inocula (Table 1) as 200ml in 500ml conical flasks (30°C and lOOrpm, in duplicate) were carried out in thermovinified must. Samples were withdrawn from all 4 fermentations when the sugar content had redu ...
A Cancer Theory Kerfuffle Can Lead to New
A Cancer Theory Kerfuffle Can Lead to New

... and 4) mutations needed for cancer do not disappear. A brief historical background can provide perspective. SMT began in 1914 with Boveri’s theory linking chromosomal changes to cancer (22). In the 1950s researchers hypothesized that cancer involved successive mutations interspersed with clonal expa ...
Ezrin NH2-Terminal Domain Inhibits the Cell
Ezrin NH2-Terminal Domain Inhibits the Cell

... also proposed in the massive membrane translocation occurring in acid-secreting gastric parietal cells (Hanzel et al., 1991). Recently identified as a tumor transplantation antigen, ezrin overexpression might confer proliferative advantage on certain tumors (Fazioli et ai., 1993). Ezrin colocaiizes ...
Quantitative Changes in Microtubule Distribution Correlate with
Quantitative Changes in Microtubule Distribution Correlate with

... et al., 2012). Since the assembly of microtubules remains constant, it appears that the observed loss of guard cell microtubule structures is likely caused largely by increasing microtubule instability as stomata close. Cortical microtubules in plant cells can exist as individuals or associate with ...
BET bromodomain inhibition suppresses TH17
BET bromodomain inhibition suppresses TH17

... hypothesized that BET inhibition might control TH17 differentiation, at least in part, by directly regulating IL-21 expression. To address this possibility, we cultured human naive T cells with recombinant IL-21, and explored the impact of BET bromodomain inhibition on IL-21 mRNA expression. As prev ...
Intracellular catalysis of disulfide bond formation by the human
Intracellular catalysis of disulfide bond formation by the human

... Many secreted proteins contain disulfide bonds, which are required for their proper folding, function and stability. In eukaryotic cells disulfide bond formation usually occurs while the protein folds in the lumen of the ER (endoplasmic reticulum). While disulfide bonds can be formed spontaneously i ...
Vacuole Membrane Protein 1 Is an Endoplasmic
Vacuole Membrane Protein 1 Is an Endoplasmic

... line Caki-2, and it was found to be essential for cell– cell contact (Sauermann et al., 2008). These results suggested a totally different function of Vmp1 in tumor cells. Therefore, the function of this protein remains controversial and seems to depend on the specific cell type studied. Vmp1 is a c ...
Extended Survivability of Prostate Cancer Cells
Extended Survivability of Prostate Cancer Cells

... liferation, cell survival, and cell death. Cell proliferation is driven and regulated by various peptide growth factors and/or cytokines. Cell survival represents the cell's intrinsic life expectancy in the absence of survival factors, many of which overlap with the growth factors/ cytokines that dr ...
251 THE EFFECTS OF ETHYL ALCOHOL ON THE ORAL CAVITY
251 THE EFFECTS OF ETHYL ALCOHOL ON THE ORAL CAVITY

... different changing processes, mediated by the enzyme system of the body. The ethyl alcohol diffuses rapidly into saliva during the drinking, and immediately after its salivary concentration is temporarily much higher than in plasma. Within 30 minutes, salivary ethanol concentration equilibrates with ...
Partitioning of nutrient transport processes in roots
Partitioning of nutrient transport processes in roots

... external Kq (Hirsch et al., 1998). Similarly, while transporters of the KUPuHAK family are capable of high af®nity Kq transport (Santa-Maria et al., 1997; Kim et al., 1998; Fu and Luan, 1998; Rubio et al., 2000), KUP1 has been reported to mediate high rates of Kq transport from solutions containing ...
T Cells + Lymphotropic Virus (MTLV) Destroying CD4 Autoimmune
T Cells + Lymphotropic Virus (MTLV) Destroying CD4 Autoimmune

... To determine the role of the MTLV-induced T cell deficiency in the autoimmune development, the deficiency was sustained by removal of the thymus 3 wk after neonatal infection, and the mice were examined at 3 mo of age for the development of autoimmune disease (Table I, Fig. 5). The virus-infected an ...
Diel patterns of growth and division
Diel patterns of growth and division

... 1993). Prochlorococcus and Synechococcus are closely related cyanobacteria with different sizes and light-harvesting antenna systems that enable them to occupy different ecological niches (for a review, see Partensky et al. 1999a). In contrast, picoeukaryotes constitute a much wider taxonomic assemb ...
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Tissue engineering



Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.
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