Genetic Regulation of Embryonic Pattern Formation
... central vascular cylinder along the radial axis. To establish this organization, the cells of the embryo need to become specified and must differentiate into cell types in an integrated manner. The genetic regulation of this process is addressed here. We focus on data from Arabidopsis but also refer ...
... central vascular cylinder along the radial axis. To establish this organization, the cells of the embryo need to become specified and must differentiate into cell types in an integrated manner. The genetic regulation of this process is addressed here. We focus on data from Arabidopsis but also refer ...
Suppression by Filarial Parasites Not IL
... profound proliferative suppression was still observed. This demonstrated that suppression was an active process and not due to an absence of costimulatory molecules or reduced numbers of effective APC. Moreover, while suppression could be transferred with supernatants from cultured PEC, this was not ...
... profound proliferative suppression was still observed. This demonstrated that suppression was an active process and not due to an absence of costimulatory molecules or reduced numbers of effective APC. Moreover, while suppression could be transferred with supernatants from cultured PEC, this was not ...
CAVATAS STUDY 5 years restenosis rate: 30% HR 0.43 (stent
... After vascular reconstruction, luminal narrowing is in part caused by intimal thickening, the consequence of endothelial injury and inflammation, smooth muscle cell hyperplasia, and extracellular matrix accumulation. It may be possible to induce these lesions to shrink. ...
... After vascular reconstruction, luminal narrowing is in part caused by intimal thickening, the consequence of endothelial injury and inflammation, smooth muscle cell hyperplasia, and extracellular matrix accumulation. It may be possible to induce these lesions to shrink. ...
Parasitic fungi on roses - Formatex Research Center
... serious pre- and postharvest diseases in more than 200 plant species, including agriculturally important crops and harvested commodities, such as grapes, tomatoes, strawberries, cucumbers, bulb flowers, cut flowers and ornamental plants [24]. The broad host range of B. cinerea results in great econo ...
... serious pre- and postharvest diseases in more than 200 plant species, including agriculturally important crops and harvested commodities, such as grapes, tomatoes, strawberries, cucumbers, bulb flowers, cut flowers and ornamental plants [24]. The broad host range of B. cinerea results in great econo ...
Cell division and leaf morphogenesis - Development
... Mironov et al., 1999). One conclusion from this work has been that although the plant cell cycle shows many similarities with that found in other eukaryotes, differences are also apparent. In particular, genome sequencing strategies have revealed a plethora of genes encoding putative components of t ...
... Mironov et al., 1999). One conclusion from this work has been that although the plant cell cycle shows many similarities with that found in other eukaryotes, differences are also apparent. In particular, genome sequencing strategies have revealed a plethora of genes encoding putative components of t ...
Expression of the Activating Transcription Factor 3 Prevents c
... N-Terminal Kinase (JNK)-induced apoptosis and induces neurite elongation via Akt activation in PC12 cells and superior nerve ganglion neurons. A DNA microarray study reveals that ATF3 expression and JNK activation induce expression of the heat shock protein 27 (Hsp27). Immunoprecipitation analysis a ...
... N-Terminal Kinase (JNK)-induced apoptosis and induces neurite elongation via Akt activation in PC12 cells and superior nerve ganglion neurons. A DNA microarray study reveals that ATF3 expression and JNK activation induce expression of the heat shock protein 27 (Hsp27). Immunoprecipitation analysis a ...
Lecture_8
... and motility. Two subunits of this protein complex are actin-related proteins (ARPs) belonging to the Arp2 and Arp3 subfamilies. The Arp3 subunit localizes to the surface of stationary bacteria and the tails of motile bacteria in tissue culture cells infected with L. monocytogenes; this is consisten ...
... and motility. Two subunits of this protein complex are actin-related proteins (ARPs) belonging to the Arp2 and Arp3 subfamilies. The Arp3 subunit localizes to the surface of stationary bacteria and the tails of motile bacteria in tissue culture cells infected with L. monocytogenes; this is consisten ...
A Role for Mitochondria in the Establishment and
... functioning in the QC. As well, these differences in enzyme activities between mitochondria in the QC and PM support the notion that mitochondria can be primary intracellular targets for the initiation of changes in cell function (Fujie et al., 1993; Smith et al., 2000). ...
... functioning in the QC. As well, these differences in enzyme activities between mitochondria in the QC and PM support the notion that mitochondria can be primary intracellular targets for the initiation of changes in cell function (Fujie et al., 1993; Smith et al., 2000). ...
The use of multi-color flow cytometry for identification of
... Studies were performed in peripheral blood samples with added potassium versenate (K2EDTA). Eight millilitres of venous blood were taken from each subject and added to 12 ml Histopaque1077 medium (Sigma-Aldrich). Peripheral blood mononuclear cells (PBMCs) were isolated by centrifugation at 2500/min ...
... Studies were performed in peripheral blood samples with added potassium versenate (K2EDTA). Eight millilitres of venous blood were taken from each subject and added to 12 ml Histopaque1077 medium (Sigma-Aldrich). Peripheral blood mononuclear cells (PBMCs) were isolated by centrifugation at 2500/min ...
KIR2DS1-Positive NK Cells Mediate Alloresponse against the C2
... described in the mouse (17–19). The activating function of multiple murine Ly49 receptors have been described, but possible ligand specificity for MHC class I Ags has been difficult to establish (17–19). Ly49D activation of NK cells by H-2Dd has been demonstrated in some studies (18, 20, 21), but li ...
... described in the mouse (17–19). The activating function of multiple murine Ly49 receptors have been described, but possible ligand specificity for MHC class I Ags has been difficult to establish (17–19). Ly49D activation of NK cells by H-2Dd has been demonstrated in some studies (18, 20, 21), but li ...
Direct interaction of two polarity complexes implicated in epithelial
... approaches have been complicated by the fact that MDCK cells are canine in origin and that siRNA strategies in polarized epithelial cells are still at an early stage. The Par3–Par6–aPKC complex is involved in polarity determination in a wide variety of tissues, including epithelia, neuroblasts, migr ...
... approaches have been complicated by the fact that MDCK cells are canine in origin and that siRNA strategies in polarized epithelial cells are still at an early stage. The Par3–Par6–aPKC complex is involved in polarity determination in a wide variety of tissues, including epithelia, neuroblasts, migr ...
Protein Kinase A Activation Down-Regulates, Whereas Extracellular
... Monoaminergic systems are related to the action of methamphetamine and cocaine. Of these, the dopaminergic system plays an important role in the methamphetamine- or cocaine-induced sensitization in animals. There are two superfamilies of dopamine (DA) receptors, designated D1- and D2-like receptors. ...
... Monoaminergic systems are related to the action of methamphetamine and cocaine. Of these, the dopaminergic system plays an important role in the methamphetamine- or cocaine-induced sensitization in animals. There are two superfamilies of dopamine (DA) receptors, designated D1- and D2-like receptors. ...
Tolerance of CD8 + T Cells Developing in Parent
... BMC thymocytes failed to respond to host antigens on day 4 (Fig. 1 B). However, low but clearly significant responses were seen on days 5 and 6. These late antihost responses were substantially higher than for BMC LN CD8 + cells (compare Fig. 1, A and B). CTL ResponsesGeneratedin Bulk Cultures. Anti ...
... BMC thymocytes failed to respond to host antigens on day 4 (Fig. 1 B). However, low but clearly significant responses were seen on days 5 and 6. These late antihost responses were substantially higher than for BMC LN CD8 + cells (compare Fig. 1, A and B). CTL ResponsesGeneratedin Bulk Cultures. Anti ...
Lineage Commitment During T cell Development
... How would you identify transcription factors involved in CD4 versus CD8 lineage commitment? Gene profiling mature CD4 vs CD8 T cells to identify ...
... How would you identify transcription factors involved in CD4 versus CD8 lineage commitment? Gene profiling mature CD4 vs CD8 T cells to identify ...
Evidence that Shh cooperates with a retinoic acid inducible co
... are induced in a mirror image fashion (Saunders and Gasseling, 1968). The molecular mechanisms underlying this process, although elusive for long time, are now starting to emerge. RA (Tickle et al., 1982), and Sonic hedgehog (Shh; Riddle, 1993; Chang et al., 1994; Lopez Martinez et al., 1995) have b ...
... are induced in a mirror image fashion (Saunders and Gasseling, 1968). The molecular mechanisms underlying this process, although elusive for long time, are now starting to emerge. RA (Tickle et al., 1982), and Sonic hedgehog (Shh; Riddle, 1993; Chang et al., 1994; Lopez Martinez et al., 1995) have b ...
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... allele for bam as described previously (McKearin and Ohlstein, 1995; Ohlstein et al., 2000). bamBG is a strong allele for bam as described previously (Chen and McKearin, 2005). piwiEP and P{hs-gal4} have been described previously (Chen and McKearin, 2005; Cox et al., 2000) Ago1k08121 has been descri ...
... allele for bam as described previously (McKearin and Ohlstein, 1995; Ohlstein et al., 2000). bamBG is a strong allele for bam as described previously (Chen and McKearin, 2005). piwiEP and P{hs-gal4} have been described previously (Chen and McKearin, 2005; Cox et al., 2000) Ago1k08121 has been descri ...
Epithelial repair is a two-stage process driven first by dying cells and
... undergoing mitosis and apoptosis. Biological and biophysical mechanisms have evolved to remove dying cells while maintaining that barrier. Cell extrusion is thought to be driven by a multicellular filamentous actin ring formed by neighbouring cells, the contraction of which provides the mechanical f ...
... undergoing mitosis and apoptosis. Biological and biophysical mechanisms have evolved to remove dying cells while maintaining that barrier. Cell extrusion is thought to be driven by a multicellular filamentous actin ring formed by neighbouring cells, the contraction of which provides the mechanical f ...
Complex Receptive Fields in Primary Visual Cortex
... (Kelly and Van Essen 1974; Gilbert and Wiesel 1979; Martin and Whitteridge 1984; Hirsch and others 1998, 2002; Martinez and others 1999, 2002). Second, in vivo recordings from neurons that were intracellularly labeled demonstrated that most layer 4 simple cells project to the superficial layers of t ...
... (Kelly and Van Essen 1974; Gilbert and Wiesel 1979; Martin and Whitteridge 1984; Hirsch and others 1998, 2002; Martinez and others 1999, 2002). Second, in vivo recordings from neurons that were intracellularly labeled demonstrated that most layer 4 simple cells project to the superficial layers of t ...
Potential hepatic stem cells reside in EpCAM cells of normal and
... epithelial cells are often referred to as ‘oval cells’ because of their ovoid nucleus (Farber, 1956). Upon activation, oval cells expand into liver parenchyma from the portal area. Oval cells express both ALB and cytokeratin 19 (CK19; KRT19 – Mouse Genome Informatics), which are hepatocytic and chol ...
... epithelial cells are often referred to as ‘oval cells’ because of their ovoid nucleus (Farber, 1956). Upon activation, oval cells expand into liver parenchyma from the portal area. Oval cells express both ALB and cytokeratin 19 (CK19; KRT19 – Mouse Genome Informatics), which are hepatocytic and chol ...
PDF
... epithelial cells are often referred to as ‘oval cells’ because of their ovoid nucleus (Farber, 1956). Upon activation, oval cells expand into liver parenchyma from the portal area. Oval cells express both ALB and cytokeratin 19 (CK19; KRT19 – Mouse Genome Informatics), which are hepatocytic and chol ...
... epithelial cells are often referred to as ‘oval cells’ because of their ovoid nucleus (Farber, 1956). Upon activation, oval cells expand into liver parenchyma from the portal area. Oval cells express both ALB and cytokeratin 19 (CK19; KRT19 – Mouse Genome Informatics), which are hepatocytic and chol ...
Mice lacking the homeodomain transcription factor
... Drosophila NK2/ventral nervous system defective (vnd) gene (Kim and Nirenberg, 1989; Price, 1993; Jimenez et al., 1995). Nkx2.2 was originally identified as a gene that is expressed in ventral regions of the developing vertebrate CNS (Price et al., 1992). In addition to Nkx2.2, five other family mem ...
... Drosophila NK2/ventral nervous system defective (vnd) gene (Kim and Nirenberg, 1989; Price, 1993; Jimenez et al., 1995). Nkx2.2 was originally identified as a gene that is expressed in ventral regions of the developing vertebrate CNS (Price et al., 1992). In addition to Nkx2.2, five other family mem ...
The cardiac pacemaker current Journal of Molecular and Cellular
... selective contribution to pacemaking, the If current is also the pharmacological target of a selective heart rate-reducing agent (ivabradine) currently used in the clinical practice. Albeit to a minor extent, the If current is also present in other spontaneously active myocytes of the cardiac conduc ...
... selective contribution to pacemaking, the If current is also the pharmacological target of a selective heart rate-reducing agent (ivabradine) currently used in the clinical practice. Albeit to a minor extent, the If current is also present in other spontaneously active myocytes of the cardiac conduc ...
Cephalostatin 1 Selectively Triggers the Release
... protein A-agarose beads (50 l) were added for an additional 2–3 h and subsequently collected by centrifugation. The beads were washed three times with 500 l of lysis buffer and resuspended in 25 l of a 3⫻ sample buffer containing 1.5% -mercaptoethanol. After addition of 25 l of 1⫻ sample buffer ...
... protein A-agarose beads (50 l) were added for an additional 2–3 h and subsequently collected by centrifugation. The beads were washed three times with 500 l of lysis buffer and resuspended in 25 l of a 3⫻ sample buffer containing 1.5% -mercaptoethanol. After addition of 25 l of 1⫻ sample buffer ...
PDGF signalling controls the migration of mesoderm cells during
... severe gastrulation defects (Ataliotis et al., 1995). The embryos showed a loss of anterior structures and failure of proper closure of the neural tube resulting in spina bifida, suggesting a defect in the anterior migration of mesodermal cells. Explanted prechordal plate mesoderm cells are able to ...
... severe gastrulation defects (Ataliotis et al., 1995). The embryos showed a loss of anterior structures and failure of proper closure of the neural tube resulting in spina bifida, suggesting a defect in the anterior migration of mesodermal cells. Explanted prechordal plate mesoderm cells are able to ...
Raven/Johnson Biology 8e Chapter 04
... properties of mitochondria and chloroplasts if these organelles were once free-living prokaryotic cells. How do your predictions match with the evidence for endosymbiosis? Answer—Based on the properties of prokaryotes listed in Table 4.3, you might predict that mitochondria and chloroplasts would ha ...
... properties of mitochondria and chloroplasts if these organelles were once free-living prokaryotic cells. How do your predictions match with the evidence for endosymbiosis? Answer—Based on the properties of prokaryotes listed in Table 4.3, you might predict that mitochondria and chloroplasts would ha ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.