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View/Open - Queen Mary University of London
View/Open - Queen Mary University of London

... Figure 1 Spatial sampling of a Barrett’s segment and associated oesophageal adenocarcinoma (OAC). (A) Overview of the opened resection specimen shows columnar metaplasia across the gastro-oesophageal junction (arrows) and a nodular OAC (arrowhead). The rectangular box indicates the longitudinal stri ...
the depression of phagocytosis by exogenous cyclic nucleotides
the depression of phagocytosis by exogenous cyclic nucleotides

... leukocytes . The investigation depends upon the use of a precise method for following ingestion . Theophylline, dibutyryl cAMP, and prostaglandins inhibited the phagocytosis of starch particles . The inhibitions caused by prostaglandins E l , E2 , and F2a (PGE I , PGE2 , and PGF2) were synergistic w ...
Intracellular calcium: friend or foe?
Intracellular calcium: friend or foe?

... outside, the cell is able to accumulate up to millimolar concentrations of the indicator inside. Though these fluors have now been used widely in many cells types their precise intracellular location has rarely been fully documented. Other complications can be ester hydrolysis, occurring extracellul ...
Cellulite: a review - Surgical And Cosmetic Dermatology
Cellulite: a review - Surgical And Cosmetic Dermatology

... lack of quality investigations on the subject. On one hand, the availability of an enormous amount of pseudo-scientific information makes serious investigations less attractive to researchers. On the other hand, in Anglo-Saxon countries, where a large part of the scientific research is conducted, th ...
structural responses of amoebae
structural responses of amoebae

... and respond to foreign cellular components are basic questions in cell biology. Amoebae are useful in attempting to answer these questions because they can be manipulated microsurgically (Jeon & Danielli, 1971; Jeon, Lorch & Danielli, 1970). Experiments on compatibility of various combinations of nu ...
Surgical Treatment
Surgical Treatment

... Knowledge of the principles and phases of wound healing are important in understanding the pathogenesis of genitourinary fistula. After injury, tissue damage and necrosis stimulate inflammation, and the process of cell regeneration begins. Initially at the injury site, new blood vessels form, termed ...
CURRICULUM VITAE
CURRICULUM VITAE

... 26. Consales CA, Mendonça RZ, Gallina NM, Pereira CA. - Cytopathic effect induced by rabies virus in McCoy cells. J.Virol.Meth. 1990,27:277. 27. Consales CA, Mendonça RZ, Lucchiari MA, Vassão RC, Pereira CA. - The macrophage action on rabies virus infection in genetically selected high and low antib ...
Tonoplast Intrinsic Protein Isoforms as Markers for Vacuolar Functions
Tonoplast Intrinsic Protein Isoforms as Markers for Vacuolar Functions

... anti–a-TIP and anti–d-TIP peptide antibodies (Figure 1B). The anti–a-TIP antibodies identified a major band of the appropriate 26-kD size, but only in the pea root tip (Figure 1B, lane 1) and pea seed (lane 5) extracts. MAb351 recognized appropriate bands of g-TIP in pea root tip (Figure 1B, lane 6) ...
Transport functions and physiological significance of 76 kDa Ral
Transport functions and physiological significance of 76 kDa Ral

... in LPO leading to the formation of toxic products including 4-HNE. It has been suggested that MRP1 may contribute to drug resistance by transporting GS-HNE. While this may be true for some cell types it appears that other transporters, including RLIP76, may play a major role in these mechanisms (Awa ...
The structure and function of the Golgi apparatus
The structure and function of the Golgi apparatus

... highly variable and polymorphic organelle plays a central role in intracellular membrane traffic. Not only does it receive all the secretory material and membrane synthesized by the endoplasmic reticulum and modifies these products by glycosylation, but also packages them and sends them in vesicular ...
Journal of Bacteriology
Journal of Bacteriology

... assay was developed for measuring attachment of Rhizobium leguminosarum cells to pea root hair tips, i.e., the site at which R. leguminosarum initiates nodulation. This form of attachment, designated as cap formation, was dependent on the incubation pH and growth phase, with optimal attachment at pH ...
as a PDF
as a PDF

... anti–a-TIP and anti–d-TIP peptide antibodies (Figure 1B). The anti–a-TIP antibodies identified a major band of the appropriate 26-kD size, but only in the pea root tip (Figure 1B, lane 1) and pea seed (lane 5) extracts. MAb351 recognized appropriate bands of g-TIP in pea root tip (Figure 1B, lane 6) ...
The Role of the Arabidopsis ELD1 Gene in Cell
The Role of the Arabidopsis ELD1 Gene in Cell

... eld1 mutant root tip was stained with TBO. The cell marked by an arrow is enlarged in the adjacent box. C, Cross-section of wild-type root showing diarch protoxylem in the stele surrounded by normal endodermis (ed) and pericycle (pe). D, Cross section of the eld1 root, showing disordered vessels, ab ...
Glycosyltransferase activity of Fringe modulates
Glycosyltransferase activity of Fringe modulates

... 200 Longwood Avenue, Boston, MA 02115, USA.) ...
Localization of Laminin B1 mRNA in Retinal Ganglion Cells by In
Localization of Laminin B1 mRNA in Retinal Ganglion Cells by In

... Departments of Ophthalmology, Physiology, and Biophysics, University of Washington, Seattle, Washington 98195 ...
Gap Junctional Communication in the Extraembryonic Tissues of the
Gap Junctional Communication in the Extraembryonic Tissues of the

... has been detected in many types of embryonic and adult cells from a large number of multicellular organisms (1, 3). It has been suggested that the ubiquitous presence of gap junctions from early stages of embryogenesis is consistent with a role in growth regulation, development, and/or pattern forma ...
Molecular - College of Biological Sciences
Molecular - College of Biological Sciences

... zebrafish (Poss et al., 2004). Mps1 is also required for mitotic arrest in response to hypoxia (Fischer et al., 2004), and it may also function in cytokinesis (Fisk et al., 2003). Centrosome duplication in vertebrate cells occurs around the G1-to-S transition, and initial studies on human Mps1 showe ...
Glucose transporters - Cambridge University Press
Glucose transporters - Cambridge University Press

... The class I facilitative transporters contain GLUT1– 4, and these have been comprehensively characterised in terms of structure, function and tissue distribution. GLUT1 is expressed particularly in the brain (including the blood – brain barrier) and erthyrocytes. Moderate levels of expression are al ...
Sampathkumar-2011-Live Cell Imaging Re - Max
Sampathkumar-2011-Live Cell Imaging Re - Max

... In eukaryotic cells, the actin and microtubule (MT) cytoskeletal networks are dynamic structures that organize intracellular processes and facilitate their rapid reorganization. In plant cells, actin filaments (AFs) and MTs are essential for cell growth and morphogenesis. However, dynamic interactio ...
From signal to form: aspects of the cytoskeleton
From signal to form: aspects of the cytoskeleton

... Rhizobium bacteria, induce root hair growth which can be recorded microscopically in a root hair deformation assay developed for Vicia sativa L. Root hair deformation is a morphogenetic process involving swelling of the hair tip and subsequent new hair outgrowth from that swelling. This response to ...
Culm strenth of a rice brittle mutant
Culm strenth of a rice brittle mutant

... mutants have been genetically identified in rice and mapped onto genetic map as follows: bc1 on chromosome 3, bc2 on chromosome5, bc3 and bc5 on chromosome 2, bc4 on chromosome 6 (Nagato and Yoshimura, 1998), bc5 is a brittle node gene and bc6 is a dominant gene. However, except bc1, the genes assoc ...
effects of disease-causing mutations associated with five
effects of disease-causing mutations associated with five

... noted, however, that the majority of Best1 accumulates in intracellular compartments in HEK293 cells [52]. As such, the different stoichiometries reported may be due to differences between a native (porcine RPE, where Best1 localizes to the basolateral plasma membrane) and a heterologous system (HEK ...
Transcription Factor Positive Regulatory Domain 4 (PRDM4) recruits Protein Arginine
Transcription Factor Positive Regulatory Domain 4 (PRDM4) recruits Protein Arginine

... Expression of SC1 in embryonic cortical NSCs SC1 mRNA is highly expressed in the developing cortex (34). We investigated the expression of SC1 protein in dissociated primary mouse cortical NSCs isolated at embryonic day 10.5 (E10.5) and cultured for up to 10 days in vitro (10DIV). We identified cell ...
Functional Role of the Fast Transient Outward K Current IA in
Functional Role of the Fast Transient Outward K Current IA in

... and maintained in vitro. Large, pyramidal-shaped neurons were selected for recordings (Desai et al., 1999), and whole-cell depolarization-activated outward K ⫹ currents were recorded in the presence of 1 ␮M TTX and 0.1 mM CdCl2 to block voltagegated Na ⫹ and Ca 2⫹ currents, respectively. Representat ...
Paradigm Shifts In Neural Induction - Works
Paradigm Shifts In Neural Induction - Works

... Even Saxén, Toivonen, and Nakamura (3), three of the few researchers whose laboratories continued to investigate primary embryonic induction during the 1970s, lamented : « Why do the scientists investigating embryonic induction lag behind their brilliant colleagues in many other areas of biology in ...
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Tissue engineering



Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.
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