1 DNA replication origin function is promoted by H3K4 di
... structural components of the COMPASS complex required for full activity (Takahashi et al. 2011). These results further support the conclusion that COMPASS enzymatic activity and H3K4 methylation are important for proliferation when Cdc6 is crippled. The poor growth of these double mutant strains cou ...
... structural components of the COMPASS complex required for full activity (Takahashi et al. 2011). These results further support the conclusion that COMPASS enzymatic activity and H3K4 methylation are important for proliferation when Cdc6 is crippled. The poor growth of these double mutant strains cou ...
CFTR modulates lung secretory cell proliferation and - AJP-Lung
... gene therapy targeting the developing lung. The CF transmembrane conductance regulator (cftr) gene was cloned without the prior knowledge of the structure and function of the protein (26, 27). Structural analysis suggested that its main function was that of a cAMPregulated chloride channel. Since th ...
... gene therapy targeting the developing lung. The CF transmembrane conductance regulator (cftr) gene was cloned without the prior knowledge of the structure and function of the protein (26, 27). Structural analysis suggested that its main function was that of a cAMPregulated chloride channel. Since th ...
Early development of the zebrafish pronephros and analysis of
... glomerulus and the overlying dorsal aorta (Fig. 2G). By 50 hpf, the medial surfaces of the two glomerular primordia have fused at the midline and the pronephric tubule can be seen in sagittal view to arc over laterally where it is connected to the pronephric ducts by a patent lumen (Fig. 2H). The di ...
... glomerulus and the overlying dorsal aorta (Fig. 2G). By 50 hpf, the medial surfaces of the two glomerular primordia have fused at the midline and the pronephric tubule can be seen in sagittal view to arc over laterally where it is connected to the pronephric ducts by a patent lumen (Fig. 2H). The di ...
TESIS DOCTORAL
... the framework of RECATABI European Project. 3D models can help us to study the biophysical, biomechanical and biochemical parameters that regulate cell differentiation. In this thesis, we have developed a 3D in vitro model to analyze the behavior of subcutaneous adipose derived progenitor cells (sub ...
... the framework of RECATABI European Project. 3D models can help us to study the biophysical, biomechanical and biochemical parameters that regulate cell differentiation. In this thesis, we have developed a 3D in vitro model to analyze the behavior of subcutaneous adipose derived progenitor cells (sub ...
The Ovule and the Embryo Sac
... gametophytes in turn produce either the male gametes (sperm) or female gametes (egg cells). In contrast to lower plant species, in which the gametophyte is the dominant, free-living generation (see Cove and Knight, 1993, this issue), gametophytes of angiosperms are smaller and less complex than the ...
... gametophytes in turn produce either the male gametes (sperm) or female gametes (egg cells). In contrast to lower plant species, in which the gametophyte is the dominant, free-living generation (see Cove and Knight, 1993, this issue), gametophytes of angiosperms are smaller and less complex than the ...
Thesis-1972D-H792p
... It should be pointed out that compounds such as penicillin, vancomycin, or D-amino acids which inhibit division activity and cell wall synthesis do not impair DNA synthesis (Grula et al., 1968), Other investigators, (Weidel, Frank, and Martin, 1964) have equated inhibition of cell division, in the p ...
... It should be pointed out that compounds such as penicillin, vancomycin, or D-amino acids which inhibit division activity and cell wall synthesis do not impair DNA synthesis (Grula et al., 1968), Other investigators, (Weidel, Frank, and Martin, 1964) have equated inhibition of cell division, in the p ...
Here - Muscle Health Research Centre
... WHILE THE ABILITY for skeletal muscle to grow, adapt, and regenerate is well known, the numerous factors governing this ability are less well defined. Furthermore, satellite cells, the primary stem cell of skeletal muscle, are critical to these capacities of skeletal muscle and the factors governing ...
... WHILE THE ABILITY for skeletal muscle to grow, adapt, and regenerate is well known, the numerous factors governing this ability are less well defined. Furthermore, satellite cells, the primary stem cell of skeletal muscle, are critical to these capacities of skeletal muscle and the factors governing ...
Planctomycetes – a phylum of emerging interest for
... location of transcription and translation, transport between compartments, and how nucleoids are distributed during division. Cytoskeletal proteins other than the FtsZ common in many Bacteria may be involved in cell division and perhaps nuclear body distribution. Some planctomycetes such as those pe ...
... location of transcription and translation, transport between compartments, and how nucleoids are distributed during division. Cytoskeletal proteins other than the FtsZ common in many Bacteria may be involved in cell division and perhaps nuclear body distribution. Some planctomycetes such as those pe ...
Full-Text PDF
... nuclear lamina [56]. This autophagic degradation of lamin B1 results in oncogene-induced senescence and subsequent tumor suppression [56]. A recent study also demonstrated that selective autophagy, which specifically degrades GATA4, a key regulator of the SASP and cellular senescence during aging, p ...
... nuclear lamina [56]. This autophagic degradation of lamin B1 results in oncogene-induced senescence and subsequent tumor suppression [56]. A recent study also demonstrated that selective autophagy, which specifically degrades GATA4, a key regulator of the SASP and cellular senescence during aging, p ...
effects of light on photosynthesis, grazing, and population dynamics
... Imaging, Inc., Mississauga, Ontario, Canada). Gross growth efficiencies (GGEs) (biomass of P. piscicida produced/biomass of cryptophyte grazed) were estimated using measured volumespecific C and N values for R. sp. and P. piscicida (see below). In the third experiment (L3), different light intensiti ...
... Imaging, Inc., Mississauga, Ontario, Canada). Gross growth efficiencies (GGEs) (biomass of P. piscicida produced/biomass of cryptophyte grazed) were estimated using measured volumespecific C and N values for R. sp. and P. piscicida (see below). In the third experiment (L3), different light intensiti ...
Extended PDF
... under laboratory conditions forms floating biofilms known as pellicles at the air-liquid interface of standing cultures (Aguilar et al., 2007; Branda et al., 2001a; Lopez et al., 2009; Vlamakis et al., 2008). Cells in the pellicles are held together by an extracellular matrix consisting of exopolysa ...
... under laboratory conditions forms floating biofilms known as pellicles at the air-liquid interface of standing cultures (Aguilar et al., 2007; Branda et al., 2001a; Lopez et al., 2009; Vlamakis et al., 2008). Cells in the pellicles are held together by an extracellular matrix consisting of exopolysa ...
Millius et al., J. Cell Sci., 2012 - Cardiovascular Research Institute
... within 1 mm of the leading edge (Fig. 2G,H). The distribution of p40 might be more restricted than either actin or WAVE2 for several reasons: other Arp2/3 complex activators such as WASP or N-WASP in combination with WAVE2 might further bias Arp2/3 to the cell periphery, or undersampling of WAVE2 pa ...
... within 1 mm of the leading edge (Fig. 2G,H). The distribution of p40 might be more restricted than either actin or WAVE2 for several reasons: other Arp2/3 complex activators such as WASP or N-WASP in combination with WAVE2 might further bias Arp2/3 to the cell periphery, or undersampling of WAVE2 pa ...
A Cellular Hypothesis for the Induction of Blossom
... distal portion of tomato fruits. The visible symptom is a necrotic lesion, which is presumed to be a consequence of cell death and the subsequent leakage of solutes into the extracellular space. Environmental factors that affect either fruit cell expansion or Ca delivery to the distal portion of the ...
... distal portion of tomato fruits. The visible symptom is a necrotic lesion, which is presumed to be a consequence of cell death and the subsequent leakage of solutes into the extracellular space. Environmental factors that affect either fruit cell expansion or Ca delivery to the distal portion of the ...
Full-Text PDF
... of Rab5, Rab10, Rab22b and Rab23 that matures to a late compartment. Approximately 1 h p.i. Mtb presence of Rab5, Rab10, Rab22b and Rab23 that matures to a late compartment. Approximately 1 h secretes ESAT-6, a pore forming toxin, and lyses the membrane promoting p62 and NDP52 anchorage. p.i. Mtb se ...
... of Rab5, Rab10, Rab22b and Rab23 that matures to a late compartment. Approximately 1 h p.i. Mtb presence of Rab5, Rab10, Rab22b and Rab23 that matures to a late compartment. Approximately 1 h secretes ESAT-6, a pore forming toxin, and lyses the membrane promoting p62 and NDP52 anchorage. p.i. Mtb se ...
The Arabidopsis trichome is an active mechanosensory switch
... By using the finite-element package, the cell wall of the trichome was represented as an elastic, isotropic shell. This shell was discretized into smaller elements that represent Mindlin– Reissner plates (ABAQUS S4 shell elements). In the baseline studies of an idealized trichome, the thickness of t ...
... By using the finite-element package, the cell wall of the trichome was represented as an elastic, isotropic shell. This shell was discretized into smaller elements that represent Mindlin– Reissner plates (ABAQUS S4 shell elements). In the baseline studies of an idealized trichome, the thickness of t ...
Temporal and Spatial Distribution of DNA Topoisomerase II Alters
... NA TOPOISOMERASE II (topo II) catalyzes the local changes in DNA topology by passing a double-stranded DNA helix through a transient double-strand break site and then rejoining the strand break.1,2 Conditional yeast mutants in the top2 gene showed that this enzymatic activity is required for segrega ...
... NA TOPOISOMERASE II (topo II) catalyzes the local changes in DNA topology by passing a double-stranded DNA helix through a transient double-strand break site and then rejoining the strand break.1,2 Conditional yeast mutants in the top2 gene showed that this enzymatic activity is required for segrega ...
Differential Effects of Rapamycin on Mammalian Target of
... individual and combined effects of rapamycin and kinase-inactive mTOR expression on a panel of mTOR-dependent cellular responses. These studies identified glycolytic activity, amino acid transporter trafficking, and Akt kinase activity as novel, mTOR-modulated functions in mammalian cells. Whereas k ...
... individual and combined effects of rapamycin and kinase-inactive mTOR expression on a panel of mTOR-dependent cellular responses. These studies identified glycolytic activity, amino acid transporter trafficking, and Akt kinase activity as novel, mTOR-modulated functions in mammalian cells. Whereas k ...
Inflammation and proliferation – a causal event of host response to
... N-terminal domain of IkBa (Karin & Ben-Neriah, 2000). H. pylori infection results in the activation of specific intracellular signalling pathways with subsequent activation of the IkB kinase (IKK) complex. This complex comprises two catalytic subunits (IKKa and IKKb) and a regulatory subunit (IKKc), ...
... N-terminal domain of IkBa (Karin & Ben-Neriah, 2000). H. pylori infection results in the activation of specific intracellular signalling pathways with subsequent activation of the IkB kinase (IKK) complex. This complex comprises two catalytic subunits (IKKa and IKKb) and a regulatory subunit (IKKc), ...
Slow axonal transport and the genesis of neuronal morphology
... Work on mitotic extracts has shown that it is also possible for cytoplasmic dynein to move microtubules relative to other microtubules (Heald et al., 1997). If this holds true in the axon as well, such forces could cause a microtubule to move either anterogradely or retrogradely, depending on which ...
... Work on mitotic extracts has shown that it is also possible for cytoplasmic dynein to move microtubules relative to other microtubules (Heald et al., 1997). If this holds true in the axon as well, such forces could cause a microtubule to move either anterogradely or retrogradely, depending on which ...
Arabidopsis Kinetochore Fiber-Associated MAP65-4
... Next, we measured the frequency of catastrophe and rescue events of MTs when cross-linked by MAP65-4. These frequencies were defined as the ratio of catastrophe and rescue events during one measurement (recordings of ;25 min). For rescue events, we considered only situations of MT regrowth when the ...
... Next, we measured the frequency of catastrophe and rescue events of MTs when cross-linked by MAP65-4. These frequencies were defined as the ratio of catastrophe and rescue events during one measurement (recordings of ;25 min). For rescue events, we considered only situations of MT regrowth when the ...
A novel meiosisspecific protein of fission yeast, Meu13p, promotes
... nuclear GFP signal appeared at about the time karyogamy occurs, after which the GFP signal intensity increased during the horse-tail period. Thus, GFP signal foci were seen from 68 6 11 to 164 6 19 min after karyogamy (in eight independent observations), and disappeared after the nucleus stopped mov ...
... nuclear GFP signal appeared at about the time karyogamy occurs, after which the GFP signal intensity increased during the horse-tail period. Thus, GFP signal foci were seen from 68 6 11 to 164 6 19 min after karyogamy (in eight independent observations), and disappeared after the nucleus stopped mov ...
PDF
... Very little further embryonic death, due to translocation-dependent genetic imbalance or other reasons, was seen after day 8. A number of females were killed at day 14 to test males for translocation heterozygosity. In the control, 7 out of 1423 implants had an amnion in which at superficial inspect ...
... Very little further embryonic death, due to translocation-dependent genetic imbalance or other reasons, was seen after day 8. A number of females were killed at day 14 to test males for translocation heterozygosity. In the control, 7 out of 1423 implants had an amnion in which at superficial inspect ...
Detergent-Insoluble Membrane Compartment CD20 Required for Its
... loops. Complete digestion of extracellular regions would be expected to result in either 8- or 15-kDa N-terminal fragments depending on whether the polypeptide is exposed at the cell surface on the carboxyl side of TM1. For these studies we used both trypsin, which cuts specifically on the carboxyli ...
... loops. Complete digestion of extracellular regions would be expected to result in either 8- or 15-kDa N-terminal fragments depending on whether the polypeptide is exposed at the cell surface on the carboxyl side of TM1. For these studies we used both trypsin, which cuts specifically on the carboxyli ...
Protein kinase Ca activation by RET: evidence for a negative
... proto-oncogenic receptor tyrosine kinase, RET and a GPI-anchored protein named GFRa. The existence of four different GFRa proteins (GFRa1, GFRa2, GFRa3 and GFRa4) gives different ligands the specificity of binding to RET-GFRa complex. The GFRa receptors are linked to the cell membrane via glycosyl-ph ...
... proto-oncogenic receptor tyrosine kinase, RET and a GPI-anchored protein named GFRa. The existence of four different GFRa proteins (GFRa1, GFRa2, GFRa3 and GFRa4) gives different ligands the specificity of binding to RET-GFRa complex. The GFRa receptors are linked to the cell membrane via glycosyl-ph ...