Eph signalling and morphogenesis - Development
... Segmentation is a basic process in embryogenesis of many invertebrate and all vertebrate embryos. In vertebrates, the two regions of the body axis that are clearly segmented are the paraxial mesoderm, which gives rise to the somites – the precursors of the segmented vertebral column (Gossler and Hra ...
... Segmentation is a basic process in embryogenesis of many invertebrate and all vertebrate embryos. In vertebrates, the two regions of the body axis that are clearly segmented are the paraxial mesoderm, which gives rise to the somites – the precursors of the segmented vertebral column (Gossler and Hra ...
Direct inhibition of CD40L expression can contribute
... CD40 ligand (CD40L; CD154) is a well-recognized costimulatory molecule that is expressed on CD4⫹ T cells shortly after activation. This early expression of CD40L appears to require only a TCR signal. More recently, it has been demonstrated that there is a second, CD28-dependent phase of expression a ...
... CD40 ligand (CD40L; CD154) is a well-recognized costimulatory molecule that is expressed on CD4⫹ T cells shortly after activation. This early expression of CD40L appears to require only a TCR signal. More recently, it has been demonstrated that there is a second, CD28-dependent phase of expression a ...
Why Belzer UW® Cold Storage Solution?
... compared to…UW hydroxyethyl starch [HES].” 2 “Various impermeants have been used to sustain the oncotic gradient across the cell membrane and prevent oedema. … UW pioneered the use of lactobionate and raffinose…Lactobionate remains the impermeant choice of having been successfully used in preservati ...
... compared to…UW hydroxyethyl starch [HES].” 2 “Various impermeants have been used to sustain the oncotic gradient across the cell membrane and prevent oedema. … UW pioneered the use of lactobionate and raffinose…Lactobionate remains the impermeant choice of having been successfully used in preservati ...
Sphingolipid homeostasis in the web of metabolic routes
... survival as demonstrated by the existence of sphingolipidoses, human diseases generated by the defects in these pathways [3]. 2.3. Regulation of sphingolipid synthesis Although SLs are essential players in cell homeostasis the regulatory mechanisms controlling this pathway have only recently begun t ...
... survival as demonstrated by the existence of sphingolipidoses, human diseases generated by the defects in these pathways [3]. 2.3. Regulation of sphingolipid synthesis Although SLs are essential players in cell homeostasis the regulatory mechanisms controlling this pathway have only recently begun t ...
- ScienceCentral
... until the early gastrula stage (stage 11.5-12). The gene expression profiles were analyzed using Xenopus Affymetrix Gene chips containing 14,400 gene transcripts. Expression of various genes during early neurogenesis was induced by BMP signaling inhibition. We found ‘Xl.1946.1.A1_’ to be a newly exp ...
... until the early gastrula stage (stage 11.5-12). The gene expression profiles were analyzed using Xenopus Affymetrix Gene chips containing 14,400 gene transcripts. Expression of various genes during early neurogenesis was induced by BMP signaling inhibition. We found ‘Xl.1946.1.A1_’ to be a newly exp ...
Anal. Chem. (2011) - American Chemical Society
... with accessibility of W and Y residues to the electrode surface and/or to competing oxidation reactions. This trend of decreasing digestion efficiency with increasing protein molecular mass was also observed in our laboratory (unpublished results) as electrochemical digestions were performed readily ...
... with accessibility of W and Y residues to the electrode surface and/or to competing oxidation reactions. This trend of decreasing digestion efficiency with increasing protein molecular mass was also observed in our laboratory (unpublished results) as electrochemical digestions were performed readily ...
Death of developing neurons: New insights and implications for
... et al., 2005), or by the proteolysis of the neurotrophin receptor p75NTR, which associates with both TrkA and TrkC (Fig. 2; Nikoletopoulou et al., 2010). Surprisingly, although TrkA and TrkC cause cell death, the structurally related TrkB receptor does not (Nikoletopoulou et al., 2010), a difference ...
... et al., 2005), or by the proteolysis of the neurotrophin receptor p75NTR, which associates with both TrkA and TrkC (Fig. 2; Nikoletopoulou et al., 2010). Surprisingly, although TrkA and TrkC cause cell death, the structurally related TrkB receptor does not (Nikoletopoulou et al., 2010), a difference ...
Male Germ Line Development in Arabidopsis
... genes (ERCC1, LGC1, and FtsZ) that are expressed preferentially or specifically in the male gametes have been isolated (Xu et al., 1998, 1999; Mori and Tanaka, 2000). Recently, large scale sequencing of sperm cell cDNAs from maize (Zea mays) has revealed a diverse complement of mRNAs (Engel et al., ...
... genes (ERCC1, LGC1, and FtsZ) that are expressed preferentially or specifically in the male gametes have been isolated (Xu et al., 1998, 1999; Mori and Tanaka, 2000). Recently, large scale sequencing of sperm cell cDNAs from maize (Zea mays) has revealed a diverse complement of mRNAs (Engel et al., ...
Male Germ Line Development in Arabidopsis
... genes (ERCC1, LGC1, and FtsZ) that are expressed preferentially or specifically in the male gametes have been isolated (Xu et al., 1998, 1999; Mori and Tanaka, 2000). Recently, large scale sequencing of sperm cell cDNAs from maize (Zea mays) has revealed a diverse complement of mRNAs (Engel et al., ...
... genes (ERCC1, LGC1, and FtsZ) that are expressed preferentially or specifically in the male gametes have been isolated (Xu et al., 1998, 1999; Mori and Tanaka, 2000). Recently, large scale sequencing of sperm cell cDNAs from maize (Zea mays) has revealed a diverse complement of mRNAs (Engel et al., ...
Archives of Microbiology
... of aquatic environments, commonly expresses several cell-surface properties that may contribute to virulence. Since many aquatic microorganisms in hostile environments can withstand starvation conditions for long periods, we examined the effect of storage under nutrientpoor conditions on the express ...
... of aquatic environments, commonly expresses several cell-surface properties that may contribute to virulence. Since many aquatic microorganisms in hostile environments can withstand starvation conditions for long periods, we examined the effect of storage under nutrientpoor conditions on the express ...
Mitochondrial permeability transition pore as a target for - AJP
... myocytes, and the samples were analyzed immediately with a fluorescent microscope. AV was shown previously to detect the early stages of apoptosis by binding to the phosphatidylserine residues, which are translocated to the external face of the cell membrane (1). Cellular necrosis was determined wit ...
... myocytes, and the samples were analyzed immediately with a fluorescent microscope. AV was shown previously to detect the early stages of apoptosis by binding to the phosphatidylserine residues, which are translocated to the external face of the cell membrane (1). Cellular necrosis was determined wit ...
Engineering a mevalonate pathway in Escherichia coli for
... certain cancers10,11, and irufloven, a third-generation semisynthetic analog of the sesquiterpene illudin S that are in late-stage clinical trials for the treatment of various refractory and relapsed cancers12,13. In general, these drugs are extracted from the host plant, in which they accumulate in ...
... certain cancers10,11, and irufloven, a third-generation semisynthetic analog of the sesquiterpene illudin S that are in late-stage clinical trials for the treatment of various refractory and relapsed cancers12,13. In general, these drugs are extracted from the host plant, in which they accumulate in ...
CHAPTER 13 – PROKARYOTE GENES: E. COLI LAC OPERON
... genes and cis-elements are not drawn to scale. (OriginalDeyholos-CC BY-NC 3.0) ...
... genes and cis-elements are not drawn to scale. (OriginalDeyholos-CC BY-NC 3.0) ...
as PDF
... a peroxyl free radical L-OO. In turn, this FR can act upon another PUFA, which will reinitiate the entire process and which would give rise to the peroxidation chain. The FR chain reaction is broken when -tocopherol, present in the membrane, transfers a hydrogen to a peroxyl FR, transforming it into ...
... a peroxyl free radical L-OO. In turn, this FR can act upon another PUFA, which will reinitiate the entire process and which would give rise to the peroxidation chain. The FR chain reaction is broken when -tocopherol, present in the membrane, transfers a hydrogen to a peroxyl FR, transforming it into ...
The circadian clock of cyanobacteria
... cyanobacterial clock Efficient genetic complementation of mutant phenotypes is possible in Synechococcus by introduction of a wild-type genomic DNA library into an array of cells. In this way, a gene cluster composed of three novel open reading frames was identified in DNA fragments recovered from r ...
... cyanobacterial clock Efficient genetic complementation of mutant phenotypes is possible in Synechococcus by introduction of a wild-type genomic DNA library into an array of cells. In this way, a gene cluster composed of three novel open reading frames was identified in DNA fragments recovered from r ...
Dual function for cloche in hematopoiesis - Development
... for erythropoiesis (Pevny et al., 1991) and Gata-2 for the production of primitive and definitive erythroid cells, mast cells, and during T- and B-cell lymphopoiesis (Tsai et al., 1994). SCL (a.k.a. Tal-1) is required at the stem cell level for the specification of all blood lineages (Shivdasani et ...
... for erythropoiesis (Pevny et al., 1991) and Gata-2 for the production of primitive and definitive erythroid cells, mast cells, and during T- and B-cell lymphopoiesis (Tsai et al., 1994). SCL (a.k.a. Tal-1) is required at the stem cell level for the specification of all blood lineages (Shivdasani et ...
Host Immune Modulation Mycobacterial Capsular Polysaccharides
... escapes its containment and causes active disease (2, 3). The interaction between M. tuberculosis and the host immune system is very complex (4, 5). An important question is how the bacillus survives its hostile environment, that is, the intracellular compartments of the macrophage, and thereby is a ...
... escapes its containment and causes active disease (2, 3). The interaction between M. tuberculosis and the host immune system is very complex (4, 5). An important question is how the bacillus survives its hostile environment, that is, the intracellular compartments of the macrophage, and thereby is a ...
Regulation of erythropoiesis
... production of EPO under hypoxia condition by osteoblasts in bone marrow microenvironment is sufficient to drive erythropoiesis; Small molecules that inhibit PHD could pharmacologically activate HIF pathway and rescue anemia (in trial). In patients with renal failure, in addition to hepatocytes, os ...
... production of EPO under hypoxia condition by osteoblasts in bone marrow microenvironment is sufficient to drive erythropoiesis; Small molecules that inhibit PHD could pharmacologically activate HIF pathway and rescue anemia (in trial). In patients with renal failure, in addition to hepatocytes, os ...
G α 12/13 regulate epiboly by inhibiting E
... Solnica-Krezel and Driever, 1994). However, in embryos overexpressing G␣13a, a sizable gap was formed between the YSN and the dcm (Fig. 1, B and B⬘), which indicates that epibolic movement of the deep cells lags behind the movement of the YSL. Thus, the distance between the dcm and the vegetal pole ...
... Solnica-Krezel and Driever, 1994). However, in embryos overexpressing G␣13a, a sizable gap was formed between the YSN and the dcm (Fig. 1, B and B⬘), which indicates that epibolic movement of the deep cells lags behind the movement of the YSL. Thus, the distance between the dcm and the vegetal pole ...
Conference22 - Zodletone Spring
... • The majority of sequences described here using the Planctomycetes-biased primers were associated with candidate class WPS-1 (27 OTUs). These OTUs belonged to three different monophyletic lineages within this class (group a, b, and c in figure 1). Interestingly, many of the most similar clones to Z ...
... • The majority of sequences described here using the Planctomycetes-biased primers were associated with candidate class WPS-1 (27 OTUs). These OTUs belonged to three different monophyletic lineages within this class (group a, b, and c in figure 1). Interestingly, many of the most similar clones to Z ...
A Putative Role for Natriuretic Peptides in Fish Osmoregulation
... similar to that described in isolated mammalian vascular smooth muscle rings (Fig. 2). Interestingly, eel ANP and killifish CNP do not show any greater efficacy in relaxing ventral aortic rings from a teleost, suggesting that there may be as much variability of ANP sequences within the piscine verte ...
... similar to that described in isolated mammalian vascular smooth muscle rings (Fig. 2). Interestingly, eel ANP and killifish CNP do not show any greater efficacy in relaxing ventral aortic rings from a teleost, suggesting that there may be as much variability of ANP sequences within the piscine verte ...
Ligand Maintenance of Regulatory T Cells via GITR for B Cells in
... in a significant reduction in the number of gadolinium-enhancing lesions, providing evidence that B cells play a pathogenic role in MS (6, 7). Evidence that rituximab also depletes regulatory B cells are reports that its treatment for autoimmunity has led to severe exacerbation of colitis and the sp ...
... in a significant reduction in the number of gadolinium-enhancing lesions, providing evidence that B cells play a pathogenic role in MS (6, 7). Evidence that rituximab also depletes regulatory B cells are reports that its treatment for autoimmunity has led to severe exacerbation of colitis and the sp ...
PDF - IRCMS
... The mesoderm germ layer gives rise to the most diverse array of cell types in the animal body. One of the earliest steps in generating this diversity is the patterning of mesoderm precursors along the dorsoventral (D/V) body axis, the molecular mechanisms of which remain poorly understood. In both v ...
... The mesoderm germ layer gives rise to the most diverse array of cell types in the animal body. One of the earliest steps in generating this diversity is the patterning of mesoderm precursors along the dorsoventral (D/V) body axis, the molecular mechanisms of which remain poorly understood. In both v ...
The Induction of 72-kD Gelatinase in T Cells upon Adhesion to
... and tissue invasion. Since migrating T cells have an invasive characteristic, we propose that 72-kD gelatinase is likely an important component of T cell migration. In inflammatory diseases, T cells invade the perivascular tissue where they cause damage to the tissue. The class of T cells which give ...
... and tissue invasion. Since migrating T cells have an invasive characteristic, we propose that 72-kD gelatinase is likely an important component of T cell migration. In inflammatory diseases, T cells invade the perivascular tissue where they cause damage to the tissue. The class of T cells which give ...
Connection of the Mitochondrial Outer and Inner Membranes by
... the ⌬fzo1 deletion mutant which is rho0, that is, it lacks mitochondrial DNA (Rapaport et al., 1998). This strain was crossed with its isogenic wild-type strain YPH500 (Sikorski and Hieter, 1989). The resulting diploid strain was sporulated and tetrads were dissected. One rho⫹ clone was isolated tha ...
... the ⌬fzo1 deletion mutant which is rho0, that is, it lacks mitochondrial DNA (Rapaport et al., 1998). This strain was crossed with its isogenic wild-type strain YPH500 (Sikorski and Hieter, 1989). The resulting diploid strain was sporulated and tetrads were dissected. One rho⫹ clone was isolated tha ...