• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
The neutrophil in vascular inflammation
The neutrophil in vascular inflammation

... neutrophils would move out of the vasculature and away from the vessel. Once they have emigrated, neutrophils need to migrate toward the bacterial focus or the dying cells without being distracted by what would then be an opposing IL-8 gradient coming from the vasculature. Receptor internalization o ...
Respiratory question - Sinoe Medical Association
Respiratory question - Sinoe Medical Association

... between the lungs and the thoracic wall C. inspiration occurs as the direct result of an increase in intra pleural and intra-alveolar pressure D. A and B only ...
Lecture 06, case study - Taxol - Cal State LA
Lecture 06, case study - Taxol - Cal State LA

... A drug like Taxol probably could not have been developed through rational drug design (2) Microtubules are so unstable, they cannot be crystalized for structural studies - except by treating them with Taxol! - the binding site of Taxol was thus defined by electron crystallographic studies of tubulin ...
Name - WordPress.com
Name - WordPress.com

... of Phylum Annelida. An earthworm is quite well-adapted to a life of burrowing through the soil. Its streamlined shape helps it move through the soil. A coating of mucus secreted by the skin lubricates the earthworm as it passes through the soil. The mucus coating also helps oxygen pass through the e ...
S. cerevisiae Mitotic Exit Activator
S. cerevisiae Mitotic Exit Activator

... The key roles of the S phase cyclins are to activate DNA replication and spindle pole body duplication and to prevent the inappropriate re-initiation of DNA replication upon completion of S phase (Dahmann et al., 1995). Although the S phase and mitotic cyclins are expressed at different times, they ...
Thesis-1972D-H792p
Thesis-1972D-H792p

... It should be pointed out that compounds such as penicillin, vancomycin, or D-amino acids which inhibit division activity and cell wall synthesis do not impair DNA synthesis (Grula et al., 1968), Other investigators, (Weidel, Frank, and Martin, 1964) have equated inhibition of cell division, in the p ...
DENTAL PLAQUE
DENTAL PLAQUE

... • The environmental parameters of the subgingival region differ from those of the supragingival region. The gingival crevice or pocket is bathed by the flow of crevicular fluid, which contains many substances that the bacteria may use as nutrients. • Host inflammatory cells and mediators are likely ...
An Auxin Gradient and Maximum in the Arabidopsis
An Auxin Gradient and Maximum in the Arabidopsis

... for each line was calculated (Figure 2A). The volume and finally the weight of the protoplasts were then calculated from their average diameters, assuming that cells of all types had an equal density, equivalent to that of water. Immediately after protoplast isolation, the volume of the cells showed ...
Western et al., 2001 - UBC Blogs
Western et al., 2001 - UBC Blogs

... pectinaceous mucilage from the epidermal cells. Staining with Ruthenium red (Western et al., 2000) and studies with several pectin-specific antibodies (Willats et al., 2001) revealed that there are both an outer, diffuse layer, and an inner, dense capsule of mucilage directly surrounding the seed as ...
In Vitro Reconstitution of SCF Substrate Ubiquitination with Purified
In Vitro Reconstitution of SCF Substrate Ubiquitination with Purified

... tagged Uba1 under control of a copper‐inducible promoter. A total of 2 g was loaded and run on an 8% SDS‐containing polyacrylamide gel followed by Coomassie staining. (B) Cdc34 was purified from E. coli strain BL21(DE3)pLysS transformed with a pET11b plasmid that contains the CDC34 open reading fra ...
Maternal Torso-Like Coordinates Tissue Folding During
Maternal Torso-Like Coordinates Tissue Folding During

... sensitive to gene dosage of RhoGEF2, a critical mediator of Rho1-dependent ventral cell shape changes during furrow formation, suggesting that Tsl may act in this pathway. In addition, loss of tsl strongly suppressed the effects of ectopic expression of Fog, a secreted protein that promotes apical c ...
Auxin Polar Transport 1s Essential for the
Auxin Polar Transport 1s Essential for the

... Three different auxin transport inhibitors, 9-hydroxyfluorene9-carboxylic acid (HFCA), frans-cinnamic acid, and 2,3,5-triiodobenzoic acid (TIBA), were added at various concentrations to both the bottom and top layers of the ECM to determine their effects on embryo development. At the range of concen ...
THE REGULATION OF ALLERGIC AIRWAY DISEASE BY TYPE V
THE REGULATION OF ALLERGIC AIRWAY DISEASE BY TYPE V

... Isolation of lung mononuclear cells .......................................................................34 Isolation of murine splenocytes and total lymph node cells ..................................34 Quantitative real-time PCR of cytokines ...................................................... ...
A Dynamic Analog Concurrently-Processed Adaptive Chip
A Dynamic Analog Concurrently-Processed Adaptive Chip

... A Dynamic Analog ConcurrentlyProcessed Adaptive Chip Virtuoso Layout of tanh with interdigitated matching ...
Multiple Poliovirus-Induced Organelles Suggested By
Multiple Poliovirus-Induced Organelles Suggested By

... have evolved mechanisms to increase multiplicity of infection, for example by leaving cells in vesicles and  perhaps  entering  that  way  [4]  or  by  attaching  to  bacterial  surface  polysaccharides  and  entering  in  association with these organisms [5].    ...
pep biology - Pinelands` Enrichment Program
pep biology - Pinelands` Enrichment Program

... plumule, radicle, seed coat, viability. ...
Boundless Study Slides
Boundless Study Slides

... • growth factor a naturally-occurring substance capable of stimulating cellular growth, proliferation, and cellular differentiation • GTP-binding protein a protein which binds GTP and catalyzes its conversion to GDP • hydrophobic lacking an affinity for water; unable to absorb, or be wetted by water ...
Ocular Drug Delivery
Ocular Drug Delivery

... injected into the vitreous cavity; however, drug distribution is not uniform. Although small molecules can rapidly diffuse throughout the vitreous fluid, the distribution of macromolecules is restricted or limited. After IVT administration, drug elimination depends on the molecular weight of the com ...
The ARRIVE Guidelines Checklist Animal Research: Reporting In
The ARRIVE Guidelines Checklist Animal Research: Reporting In

... intestinal tract to produce SIgA and Th2 cytokines in both malnourished and normal mice, enhancing the immune function of the intestinal mucosa. Whether in mice or in human, SIgA play a key role in the immunological response of respiratory airway to allergens or pathogenic microorganisms. In an infl ...
Regeneration in the aging peripheral nervous system The Harvard
Regeneration in the aging peripheral nervous system The Harvard

... for. This theory relies on the fact that many, if not all, genes are pleiotropic, likely exerting some beneficial effects and some negative ones. From an evolutionary point of view, a small beneficial effect early in life will thus greatly outweigh a large negative effect later in life. Again, this ...
Phalloidin
Phalloidin

... Please visit www.biotium.com to view our full selection of CF™ dye and R-PE conjugates, including labeled primary and secondary antibodies, streptavidin, Annexin V, a-bungarotoxin, and Mix-n-Stain antibody labeling kits. Biotium also offers a variety of apoptosis and cell viability assays for flow c ...
Mitochondrial behaviour throughout the lytic cycle of Toxoplasma
Mitochondrial behaviour throughout the lytic cycle of Toxoplasma

... novel observations pave the way for future research to identify molecular mechanisms involved in mitochondrial distribution in Toxoplasma and the consequences of these mitochondrion changes on parasite physiology. The various functions of mitochondria are governed in part by positioning of the organ ...
Redox regulation of cysteine
Redox regulation of cysteine

... There are 2 main forms of SOD in mammalian cells, MnSOD (SOD2; localized to mitochondria) and CuZnSOD, with 2 types of CuZnSOD that are found either intracellularly (SOD1) or extracellularly (SOD3). These enzymes are responsible for the conversion of superoxide to H2O2, although this occurs slowly a ...
Disulfide formation in plant storage vacuoles permits assembly
Disulfide formation in plant storage vacuoles permits assembly

... compost and vermiculite under greenhouse conditions at 15°C with a 16 hour light / 8 hour dark cycle. Prior to planting, seeds were imbibed in running water overnight. The development of Ricinus communis seeds is divided into seven stages (A to G) based on size, testa formation and state of hydratio ...
Print
Print

... lowing binding to their respective ligands (15, 100, 102). Expression of these dependence receptors creates cellular states of dependence on the associated ligands. These states of dependence are not absolute, since they can be blocked downstream in some cases by the expression of antiapoptotic gene ...
< 1 ... 78 79 80 81 82 83 84 85 86 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report