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Protection of Drosophila chromosome ends with minimal telomere
Protection of Drosophila chromosome ends with minimal telomere

... through its OB-fold domain, in a way similar to POT1 in mammals (Raffa et al. 2010; 2013). By contrast, HOAP, HipHop and HP1a form a complex that localizes not only in the direct vicinity of the chromosome extremities, where HOAP interacts directly with Moi (Raffa et al. 2009), but also occupies a r ...
Peer-reviewed Article PDF - e
Peer-reviewed Article PDF - e

... [30]. Interestingly, there was no secondary downregulation of the expression of endogenous SERCA2a, despite a dramatic overexpression of SERCA2b [30]. Alternatively, some studies have questioned whether SERCA2a and SERCA2b were interchangeable in cardiac function using transgenic mice in which the a ...
Biology
Biology

... •The food then moves through the crop, where it can be stored. •It then moves through the gizzard, where it is ground into smaller pieces. ...
Perspectives in active liquid crystals
Perspectives in active liquid crystals

... case of swimming bacteria and active colloids, or a solid, as for cells crawling on a substrate. In some cases, the medium can simply be described as a passive momentum sink, providing friction (see, for instance, [19]). This class of systems, referred to as ‘dry’, includes cells crawling on a rigid ...
VP5 autocleavage is required for efficient infection by in vitro
VP5 autocleavage is required for efficient infection by in vitro

... for aquareovirus entry, a dual-expressed VP5 and VP7 (vAcGCRV-VP5/VP7) and singly expressed VP5 or VP7 (vAcGCRV-VP5 or vAcGCRV-VP7; data not shown) recombinant baculoviruses were constructed, respectively. In addition, to determine whether the N42 residue was responsible for autocleavage of VP5, a m ...
Mast cells in Complement Dependant Tolerance
Mast cells in Complement Dependant Tolerance

... 3.2. MC in draining lymph nodes of skin grafts It has been shown that MC traffic from the local site of inflammation to secondary lymphoid organs [13-16]. Therefore, we investigated if the observed reduction in MC density in the skin grafts early after transplantation was the result of MC migration ...
BSc Lab Medicine Part-I
BSc Lab Medicine Part-I

... Bangladesh. Mention the modes of transmission of disease with example. What are the levels of prevention? What is EPI and its objectives? Give the EPI schedule. Q-5. What is malnutrition? Define & classify PEM? What are the common causes of malnutrition? Give the difference between marasmus and kwas ...
CHAPTER 5 THE MULTIPLIER 5.1 INTRODUCTION
CHAPTER 5 THE MULTIPLIER 5.1 INTRODUCTION

... 14T adder improves the power dissipation by 27% when compared to the other multipliers architecture. Wallace tree multiplier using new improved 14T adder cell dissipates small amount of power, which shall be called as low power multiplier. As mentioned earlier, the performance of many larger circui ...
Traffic between the plant endoplasmic reticulum and Golgi
Traffic between the plant endoplasmic reticulum and Golgi

... compartments [30], or precursors of the prevacuolar compartment. Microscopy supports the existence of a TGNlike structure at the plant Golgi [31,32]. Earlier studies have also pointed to the existence of subdomains of the TGN [33]. The golgin AtGRIP is thought to localize at the transGolgi, although ...
Fanconi anemia protein FANCD2 inhibits TRF1
Fanconi anemia protein FANCD2 inhibits TRF1

... [14-18]. In most human somatic cells telomeres undergo shortening with each cycle of cell division due to what is known as the “end-replication problem” [19,20]. To prevent such shortening, a specialized enzyme called telomerase serves to maintain telomere length [21]. In normally dividing somatic c ...
hermoregulation
hermoregulation

... Concept 40.1: Animal form and function are correlated at all levels of organization • Size and shape affect the way an animal interacts with its environment • Many different animal body plans have evolved and are determined by the genome ...
Biology For Dummies, 2nd Edition - The Official Site
Biology For Dummies, 2nd Edition - The Official Site

... Trademarks: Wiley, the Wiley Publishing logo, For Dummies, the Dummies Man logo, A Reference for the Rest of Us!, The Dummies Way, Dummies Daily, The Fun and Easy Way, Dummies.com, Making Everything Easier, and related trade dress are trademarks or registered trademarks of John Wiley & Sons, Inc. an ...
Specification of germ layer identity in the chick gastrula.
Specification of germ layer identity in the chick gastrula.

... © 2007 Chapman et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Essentials of Anatomy and Physiology, 9e (Marieb)
Essentials of Anatomy and Physiology, 9e (Marieb)

... A) regulate heart and breathing rates B) operate in such a way that the initial stimulus is enhanced and increases C) operate in such a way that the initial stimulus is shut off or reduced D) regulate heart and breathing rates, and operate in such a way that the initial stimulus is enhanced and incr ...
Patient #1
Patient #1

... Inheritance is autosomal dominant or recessive Family history is helpful in that there are no relatives with significant renal disease Hematuria is usually microscopic (gross hematuria may occur w/ URIs); Proteinuria is rare Diagnosis of exclusion – Send UA on family members to detect hematuria ...
Application of the photocatalytic reaction of TiO2 to disinfection and
Application of the photocatalytic reaction of TiO2 to disinfection and

... oxygen and Titanium dioxide (TiO2) in aqueous solution has been investigated .This method is effective for killing Escherichia -coli bacteria in water. TiO2 semiconductor exhibits strong bacterial activity .The aim of this research is to design a new photobioreactor and its application to sterilize ...
Branching of Sensory and Sympathetic Neurites in vitro Is Inhibited
Branching of Sensory and Sympathetic Neurites in vitro Is Inhibited

... aspects of neuronal form (Sotelo and Arsenio-Nunes, 1976; Van der Loos, 1965). It is clear, then, from a variety of studies that intrinsic regulatory factors contribute to the neuritic branching patterns of different neuronal types. In this paper we present evidence that the microtubular organizatio ...
Peptide Repertoire Class I Molecule Q10 Binds a Classical The
Peptide Repertoire Class I Molecule Q10 Binds a Classical The

... more, many of the class Ib molecules exist in soluble forms that are secreted into the serum and body fluids (5, 6). Recent studies of rodent and human members of class Ib families revealed remarkable diversity of their ligands, Ag-presenting capacities, and immune as well as nonimmune functions (7– ...
Autoregulation of Actin Synthesis by Physiological
Autoregulation of Actin Synthesis by Physiological

... emission wavelengths were 542 and 563 nm. Cellular protein was determined according to Bradford (21) in parallely cultured hepato^ cytes lysed in the presence of 5 g/1 Triton X-100. Data were expressed as ng rhodamine-phalloidin per mg cellular protein. In addition, the ratio of filamentous to non-f ...
PDF
PDF

... 1992b), and may involve a ventrally oriented invagination movement that helps round the notochord in cross section (Munro and Odell, 2002b). While this intercalation is essential, a considerable degree of tail extension is also driven by cell-shape changes and vacuolization after intercalation is co ...
The control of sarcoplasmic reticulum Ca content in cardiac muscle
The control of sarcoplasmic reticulum Ca content in cardiac muscle

... fore the larger the Ca transient, the faster the inactivation of Ca entry and therefore the smaller the Ca entry. Second, an increase in the amplitude of the Ca transient increases the efflux of Ca from the cell as NCX is more strongly activated. The net result is therefore that an increase in the a ...
Keystone Exam Study Guide
Keystone Exam Study Guide

... BIO.A.4.1.3 Describe how membrane-bound cellular organelles (e.g., endoplasmic reticulum, Golgi apparatus) facilitate the transport of materials within a cell. ...
Molecular Machinery Regulating Exocytosis
Molecular Machinery Regulating Exocytosis

... homologue of Rab11 (Li, et al., 2008; Ward, et al., 2005). Rab3 also has a role in anterograde traffic between the trans-Golgi network and recycling endosomes (Mohrmann, et al., 2002; van der Sluijs, et al., 1992). The Rab small GTPases, Sec4 in yeast and Rab11 in metazoans, facilitate trafficking o ...
Bile Formation: a Concerted Action of Membrane
Bile Formation: a Concerted Action of Membrane

... 0886-1714/99 5.00 © 2000 Int. Union Physiol. Sci./Am.Physiol. Soc. ...
Linköping University Post Print
Linköping University Post Print

... LMP do exist [23, 24]. For example, large lysosomes appears to be more susceptible to LMP than small ones [24]. The mechanism underlying LMP is still incompletely understood. Apart from cathepsins, other hydrolases [25-28], H+ (causing acidification of the cytosol) [29], Ca2+ [30], and several of t ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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