MYOCARDIAL ISCHAEMIC PRE-CONDITIONING in Open Heart
... potential, which subsequently determines the propagation velocity of the action potential through the heart (Wit Al et al,1997). The action potential can be divided into four phases(Figure.1), in the fast response action potential, the resting (Vm) in a cardiac muscle cell is –80 to –90 mV, and pha ...
... potential, which subsequently determines the propagation velocity of the action potential through the heart (Wit Al et al,1997). The action potential can be divided into four phases(Figure.1), in the fast response action potential, the resting (Vm) in a cardiac muscle cell is –80 to –90 mV, and pha ...
Cardiomyocyte Lineage Specification in€Adult Human Cardiac
... The mechanisms controlling differentiation in adult cardiac precursor cells (CPCs) are still largely unknown. In this study, CPCs isolated from the human heart were found to produce predominantly smooth muscle cells but could be redirected to the cardiomyocyte fate by transient activation followed b ...
... The mechanisms controlling differentiation in adult cardiac precursor cells (CPCs) are still largely unknown. In this study, CPCs isolated from the human heart were found to produce predominantly smooth muscle cells but could be redirected to the cardiomyocyte fate by transient activation followed b ...
Regulation of KNOLLE syntaxin - Journal of Cell Science
... al., 1999). However, thorough analyses of yeast SNARE interactions in liposome assays have indicated a high degree of specificity of interaction between syntaxins and synaptobrevins (Fukuda et al., 2000; McNew et al., 2000; Parlati et al., 2000). KNOLLE is a distant member of the plasma membrane sub ...
... al., 1999). However, thorough analyses of yeast SNARE interactions in liposome assays have indicated a high degree of specificity of interaction between syntaxins and synaptobrevins (Fukuda et al., 2000; McNew et al., 2000; Parlati et al., 2000). KNOLLE is a distant member of the plasma membrane sub ...
The PDZ-GEF Dizzy regulates cell shape of migrating macrophages
... that even distribution, and the posterior-ventral part of the embryo contained less macrophages than the equivalent area of a wild-type embryo (Fig. 2E-H). Thus, dizzy mutant macrophages appeared to be slower and did not reach their destinations in time. Other aspects of the migration, such as the m ...
... that even distribution, and the posterior-ventral part of the embryo contained less macrophages than the equivalent area of a wild-type embryo (Fig. 2E-H). Thus, dizzy mutant macrophages appeared to be slower and did not reach their destinations in time. Other aspects of the migration, such as the m ...
(2) Patent Application Publication (10) Pub. No.: US 2009/0306491 A1
... the patient each time the patient wishes to interface with the system. Such replacement processes can take up to 60 min utes to perform. [0005] Another method currently being explored is a tech nique which helps to maximize the information gained from non-invasive neural prosthetics through the use ...
... the patient each time the patient wishes to interface with the system. Such replacement processes can take up to 60 min utes to perform. [0005] Another method currently being explored is a tech nique which helps to maximize the information gained from non-invasive neural prosthetics through the use ...
The basic helix–loop–helix protein BETA2 interacts with p300 to
... very low levels alone or with coexpressed E47, a ubiquitous bHLH protein (Fig. 2A, columns 1,3). Cotransfecting increasing amounts of a p300 expression plasmid further potentiated BETA2-dependent transcription to >100-fold greater than the reporter alone. The failure of p300 to transactivate the rep ...
... very low levels alone or with coexpressed E47, a ubiquitous bHLH protein (Fig. 2A, columns 1,3). Cotransfecting increasing amounts of a p300 expression plasmid further potentiated BETA2-dependent transcription to >100-fold greater than the reporter alone. The failure of p300 to transactivate the rep ...
Glucose transporters - Cambridge University Press
... capacity) transports the bulk of plasma glucose from the glomerular filtrate. Any remaining glucose is recovered by SGLT1 (high affinity, low capacity) thus preventing glucose loss in the urine. However, controversy exists as to whether SGLT2 is the major renal glucose transporter (Hediger et al. 19 ...
... capacity) transports the bulk of plasma glucose from the glomerular filtrate. Any remaining glucose is recovered by SGLT1 (high affinity, low capacity) thus preventing glucose loss in the urine. However, controversy exists as to whether SGLT2 is the major renal glucose transporter (Hediger et al. 19 ...
SKIP controls lysosome positioning using a composite kinesin
... driven by a dynamic network of inter- and intra-molecular interactions. ...
... driven by a dynamic network of inter- and intra-molecular interactions. ...
Classes of programmed cell death in plants
... tonoplast rupture cause the ricinosomes to break open, releasing the proteases, which become activated and help degrade the cytoplasm (Senatore et al., 2009). ‘Autolytic’ PCD in barley seed aleurone cells was associated with the induction of a gene encoding cathepsin B, a cysteine protease (Martinez ...
... tonoplast rupture cause the ricinosomes to break open, releasing the proteases, which become activated and help degrade the cytoplasm (Senatore et al., 2009). ‘Autolytic’ PCD in barley seed aleurone cells was associated with the induction of a gene encoding cathepsin B, a cysteine protease (Martinez ...
A Pd8 Tetrafacial Molecular Barrel as Carrier for Water Insoluble
... Live cell imaging has become an indispensable method for diagnostics as well as biological studies in order to track dynamics and functions of various cellular processes. The foremost important factors associated with a cell imaging fluorophore are membrane permeability, cell viability, solubility, a ...
... Live cell imaging has become an indispensable method for diagnostics as well as biological studies in order to track dynamics and functions of various cellular processes. The foremost important factors associated with a cell imaging fluorophore are membrane permeability, cell viability, solubility, a ...
Hepatitis A Virus Adaptation to Cellular Shutoff Is Driven by Dynamic
... specific condition of AMD, infected cells (multiplicity of infection [MOI] of 1) from a T-175 flask were harvested by trypsin treatment, collected by centrifugation, resuspended in 500 l of NT buffer (0.1 M NaCl, 10 mM Tris-HCl, 1% NP-40, pH 7.4), and incubated for 30 min at room temperature. These ...
... specific condition of AMD, infected cells (multiplicity of infection [MOI] of 1) from a T-175 flask were harvested by trypsin treatment, collected by centrifugation, resuspended in 500 l of NT buffer (0.1 M NaCl, 10 mM Tris-HCl, 1% NP-40, pH 7.4), and incubated for 30 min at room temperature. These ...
Regulation of leg size and shape by the Dachsous
... Regeneration depends on the recognition of tissue loss and the subsequent restoration of the relevant structure. Many insights into the mechanisms underlying such regeneration processes have been obtained from studies on limb regeneration in urodeles (for reviews, see Nye et al., 2003; Brockes and K ...
... Regeneration depends on the recognition of tissue loss and the subsequent restoration of the relevant structure. Many insights into the mechanisms underlying such regeneration processes have been obtained from studies on limb regeneration in urodeles (for reviews, see Nye et al., 2003; Brockes and K ...
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... Regeneration depends on the recognition of tissue loss and the subsequent restoration of the relevant structure. Many insights into the mechanisms underlying such regeneration processes have been obtained from studies on limb regeneration in urodeles (for reviews, see Nye et al., 2003; Brockes and K ...
... Regeneration depends on the recognition of tissue loss and the subsequent restoration of the relevant structure. Many insights into the mechanisms underlying such regeneration processes have been obtained from studies on limb regeneration in urodeles (for reviews, see Nye et al., 2003; Brockes and K ...
Inositol trisphosphate and calcium oscillations
... extent either by the addition of higher doses of 5-HT or by increasing the external level of Ca2+. I then measured the accumulation of InsP1 under these two conditions. If InsP3 formation is driving each transient, the expectation would be for the turnover of inositol phosphates to increase for both ...
... extent either by the addition of higher doses of 5-HT or by increasing the external level of Ca2+. I then measured the accumulation of InsP1 under these two conditions. If InsP3 formation is driving each transient, the expectation would be for the turnover of inositol phosphates to increase for both ...
Dispersal of Golgi matrix proteins during mitotic Golgi
... ER (Zaal et al., 1999). If the entire Golgi is in the ER, then post-mitotic Golgi biogenesis must occur de novo. Interestingly, this latter work used Golgi enzymes rather than any golgin or GRASP as marker proteins. It was subsequently observed that during BFA-induced Golgi collapse, Golgi enzymes m ...
... ER (Zaal et al., 1999). If the entire Golgi is in the ER, then post-mitotic Golgi biogenesis must occur de novo. Interestingly, this latter work used Golgi enzymes rather than any golgin or GRASP as marker proteins. It was subsequently observed that during BFA-induced Golgi collapse, Golgi enzymes m ...
Cellular Pathology
... Result In Intracellular Accumulations 1) Normal endogenous substance produced at normal or increased rate, with inadequate rate of metabolism: Hepatic fatty change Plasma cell Russell bodies ...
... Result In Intracellular Accumulations 1) Normal endogenous substance produced at normal or increased rate, with inadequate rate of metabolism: Hepatic fatty change Plasma cell Russell bodies ...
The Lymphatic System Homotoxicological Approach
... diffusion of certain substances in and out of the capillary lumen. E.g. oxygen and water diffuse out into the interstitial spaces, and carbon dioxide into the capillaries. The endothelial lining also allows the passage of nutritients and other substances by active transport. Another mechanism of tra ...
... diffusion of certain substances in and out of the capillary lumen. E.g. oxygen and water diffuse out into the interstitial spaces, and carbon dioxide into the capillaries. The endothelial lining also allows the passage of nutritients and other substances by active transport. Another mechanism of tra ...
Transcriptionally repressed germ cells lack a subpopulation of
... (Seydoux et al., 1996). In this organism, several newly transcribed mRNAs have been detected in somatic blastomeres as early as the 4-cell stage, but none to date have been detected in germ-line blastomeres (Seydoux and Fire, 1994; Seydoux et al., 1996). This soma-germ line difference was shown to d ...
... (Seydoux et al., 1996). In this organism, several newly transcribed mRNAs have been detected in somatic blastomeres as early as the 4-cell stage, but none to date have been detected in germ-line blastomeres (Seydoux and Fire, 1994; Seydoux et al., 1996). This soma-germ line difference was shown to d ...
Course Packet - Austin Community College
... vertebrates just to collect for this project, don’t steal nests that are “in use”, don’t violate laws and bans on hunting or collecting certain lifeforms, eg. we don’t want any endangered species, etc; more specific details below 6. you will not get these items back; so don’t bring in a family treas ...
... vertebrates just to collect for this project, don’t steal nests that are “in use”, don’t violate laws and bans on hunting or collecting certain lifeforms, eg. we don’t want any endangered species, etc; more specific details below 6. you will not get these items back; so don’t bring in a family treas ...
Preneoplastic lesions as end points in
... The evaluation of the carcinogenic risk deriving from chemical compounds depends mainly on conventional histopathology up to the present. The accepted end point in carcinogenicity testing is the tumor as defined histologically. A great disadvantage of this approach is the long lag period in the deve ...
... The evaluation of the carcinogenic risk deriving from chemical compounds depends mainly on conventional histopathology up to the present. The accepted end point in carcinogenicity testing is the tumor as defined histologically. A great disadvantage of this approach is the long lag period in the deve ...
Elevated Level of Nuclear Protein Kinase C in
... nucleus may play a role in modulating nuclear events to promote the development of multidrug resistance in MCF-7 cells. ...
... nucleus may play a role in modulating nuclear events to promote the development of multidrug resistance in MCF-7 cells. ...
Impact of invertase overexpression on cell size
... et al. (1997). In particular, transgenic tobacco plants that overexpressed a yeast-derived invertase in the vacuole exhibited a severe increase in turgor pressure within epidermis and mesophyll cells. In contrast, turgor and osmotic pressure remained largely constant during rapid stem elongation in ...
... et al. (1997). In particular, transgenic tobacco plants that overexpressed a yeast-derived invertase in the vacuole exhibited a severe increase in turgor pressure within epidermis and mesophyll cells. In contrast, turgor and osmotic pressure remained largely constant during rapid stem elongation in ...
Transcriptionally repressed germ cells lack a
... (Seydoux et al., 1996). In this organism, several newly transcribed mRNAs have been detected in somatic blastomeres as early as the 4-cell stage, but none to date have been detected in germ-line blastomeres (Seydoux and Fire, 1994; Seydoux et al., 1996). This soma-germ line difference was shown to d ...
... (Seydoux et al., 1996). In this organism, several newly transcribed mRNAs have been detected in somatic blastomeres as early as the 4-cell stage, but none to date have been detected in germ-line blastomeres (Seydoux and Fire, 1994; Seydoux et al., 1996). This soma-germ line difference was shown to d ...
The Respiratory System - AB Course Sharing Hub
... draw enough oxygen into their lungs when they breathe. By wearing oxygen masks, climbers can get enough oxygen to stay alive as they near the summit. Without this technology, climbers would become confused and soon lose consciousness. Oxygen is so important to life that even minutes without it can l ...
... draw enough oxygen into their lungs when they breathe. By wearing oxygen masks, climbers can get enough oxygen to stay alive as they near the summit. Without this technology, climbers would become confused and soon lose consciousness. Oxygen is so important to life that even minutes without it can l ...
Regulation of Metabolic Events during Embryo Development
... The overall aim of this thesis was to identify and characterize metabolic and biochemical events that are involved in regulation of embryo development in Norway spruce. Embryogenesis involves coordination of multicellular patterning events which are critical for establishment of the apical-basal pla ...
... The overall aim of this thesis was to identify and characterize metabolic and biochemical events that are involved in regulation of embryo development in Norway spruce. Embryogenesis involves coordination of multicellular patterning events which are critical for establishment of the apical-basal pla ...