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Lysenin: A sphingomyelin specific pore
Lysenin: A sphingomyelin specific pore

... when the cell density is low and thus cells are not polarized. In contrast, lysenin does not bind to the apical surface of highly polarized cells [33]. Selective recognition of basolateral surface by lysenin was confirmed by adding lysenin from the apical and basolateral sides of fully polarized MDC ...
Recent developments in the cell and molecular biology of root hairs
Recent developments in the cell and molecular biology of root hairs

... cells overlying cortical periclinal walls (i.e. epidermal cells directly overlying the cortical cells) develop a hairless state. Alterations in TTG activity caused developing epidermal cells to misinterpret their position and differentiate into inappropriate cell types. The ttg mutations are also as ...
Solid Tumour Section Testis: Spermatocytic seminoma Atlas of Genetics and Cytogenetics
Solid Tumour Section Testis: Spermatocytic seminoma Atlas of Genetics and Cytogenetics

... from the normal testis parenchyma but some tumours seem composed of smaller nodules. In rare instances, the pre-invasive intratubular spermatocytic seminoma can be detected (Eble, 1994). There is no specific immunocytological marker for spermatocytic seminoma. Genes/antigens that are highly expresse ...
Lipopolysaccharide modulates neutrophil recruitment and
Lipopolysaccharide modulates neutrophil recruitment and

... activation and dyslipidemia resulting from the aberrant elevated postprandial chylomicron production in metabolic syndrome, as well as the dietary endotoxins, such as LPS associated with them (32, 37, 74). LPS, a critical cell wall component of most gram-negative bacteria, has been identified as the ...
The Role of Lysosomes in Molluscan Inflammation1
The Role of Lysosomes in Molluscan Inflammation1

... applicable to invertebrates. Nevertheless, nonspecific cellular response does occur in become chronic. Chronic inflammatory these animals. At this point, a seldom responses are characterized by an infiltraremembered fact relative to inflammation tion of lymphocytes and cells of the monoin molluscs b ...
7th_Grade_Curriculum_Map_2012-13
7th_Grade_Curriculum_Map_2012-13

... SC.7.N.3.1 - Recognize and explain the difference between theories and laws and give several examples of scientific theories and the evidence that supports them. SC.7.N.3.2 - Identify the benefits and limitations of the use of scientific models. MA.6.A.3.6 – Construct and analyze tables, graphs, and ...
7th_Gr_Science_Curriculum_Map_2012
7th_Gr_Science_Curriculum_Map_2012

... SC.7.N.3.1 - Recognize and explain the difference between theories and laws and give several examples of scientific theories and the evidence that supports them. SC.7.N.3.2 - Identify the benefits and limitations of the use of scientific models. MA.6.A.3.6 – Construct and analyze tables, graphs, and ...
Lesson 19
Lesson 19

... – There are three major types of blood vessels: arteries, veins, and capillaries. – An artery is a blood vessel that carries blood away from the heart. • A coronary artery supplies nutrients and oxygen to the heart muscle. • A pulmonary artery carries blood from the heart to the lungs. Click the mou ...
7th_Gr_ScienceWGizmos_Curriculum_Map_2012
7th_Gr_ScienceWGizmos_Curriculum_Map_2012

... SC.7.N.3.1 - Recognize and explain the difference between theories and laws and give several examples of scientific theories and the evidence that supports them. SC.7.N.3.2 - Identify the benefits and limitations of the use of scientific models. MA.6.A.3.6 – Construct and analyze tables, graphs, and ...
Full text Pdf
Full text Pdf

... corresponding with lines of embryological fusion. Perhaps, totipotential cells at these sites retain their ability to develop into endothelial cells and /or pericytes, and, under the influence of angiogenesis stimulation, they develop into blood vessels. A less common, alternative pattern of diffuse ...
GO - Buffalo Ontology Site
GO - Buffalo Ontology Site

... truth-value as the sentence with which we begin ...
Factors Associated with Successful Tissue Harvest for Descemet`s
Factors Associated with Successful Tissue Harvest for Descemet`s

... warming donor tissue to room temperature were recorded for each harvest attempt. Twenty-eight of forty (70%) Descemet’s membranes were peeled successfully with this technique. After adjusting for donor cornea age, sex, and time from death to preservation, soaking the donor tissue for 60 minutes in a ...
Biology I Semester 1 Quarter 1 Exam Study Guide 2014-10
Biology I Semester 1 Quarter 1 Exam Study Guide 2014-10

... 17. A solution with a pH of 3 has ____________________ times more hydronium ions than a solution with a pH of 6. 18. Buffers are important because body fluids must be maintained within a relatively narrow range of ____________________. 19. Water is very effective at dissolving other polar substances ...
Chapter 17. Cytoskeleton Chapter 17. Cytoskeleton Chapter 17
Chapter 17. Cytoskeleton Chapter 17. Cytoskeleton Chapter 17

... Chapter 17. Cytoskeleton • Cells are not “bags of enzymes”, but rather organized in three dimensions. • This organization is carried out by the cytoskeleton, the “bones and muscles” (and more) of cells. • Cells are thousands of times larger than a typical molecule. Therefore the cytoskeleton must lo ...
The Neuronal Membrane at Rest
The Neuronal Membrane at Rest

... Channel Proteins. The exposed surface of a protein may be chemically heterogeneous. Regions where nonpolar R groups are exposed will be hydrophobic and will tend to associate readily with lipid. Regions with exposed polar R groups will be hydrophilic and will tend to avoid a lipid environment. There ...
Oxygen Limitation Suppresses Reactive Oxygen Species Formation
Oxygen Limitation Suppresses Reactive Oxygen Species Formation

... Previous research showed that the formation of reactive oxygen species (ROS) serves as a common mechanism of bactericidal antibiotics induced cell death. The purpose of this study was to better understand the mechanism of oxygen radicals formation by assessing the effect of oxygen limitation on the ...
Marine
Marine

... fluid motion affected uptake by natural assemblages of marine bacteria in the same manner as was seen with a pure culture and to examine the assumptions of a theoretical model developed to predict the effect of fluid motion on uptake. The model is based on the assumption that fluid motion enhances u ...
Determination of the Correlation between Conductance and Architecture of Disordered ß-amyloid Channels
Determination of the Correlation between Conductance and Architecture of Disordered ß-amyloid Channels

... Introducing charge on the surrounding membrane, which replicates the effect of having charged lipids, results in the reduction of the conductance dynamic range for Scenario II (Table 3) (0.6810.36 nS) as compared to Scenario I (Table 2) (0.31-15.90 nS). The charged lipids are negatively charged, whi ...
Keystone Standards
Keystone Standards

... BIO.A.4. 1. Identify and describe the cell structures involved in transport of materials into, out of, and throughout a cell. BIO.A.4. 1.1. Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell. BIO.A.4. 1.2. Compare th ...
Presentation - MIT Lincoln Laboratory
Presentation - MIT Lincoln Laboratory

... – Each cycle, a single partner particle from the cell set is broadcast to all of the filters ...
Human Fatty Acid Transport Protein 2a/Very Long Chain Acyl
Human Fatty Acid Transport Protein 2a/Very Long Chain Acyl

... distinct patterns are generated and maintained is poorly understood, but it is reasonable to expect that the source of the fatty acid, either from endogenous or exogenous sources, will lead to different metabolic fates. These processes are likely governed by proteins and enzymes, which function in f ...
an insight of physiology of respiration in ayurveda
an insight of physiology of respiration in ayurveda

... reaches to the lungs where gaseous exchange takes place. A certain amount of blood is continuously being pumped out by hrdaya (heart) & Phupphusa (Lungs). This blood absorbs the ambarpiyush (O2) from the air present inside & leaves off its waste CO2 which is exhaled out. Supporting Acharya Sharangdh ...
Effects of phytanic acid on the vitamin E status, lipid composition and
Effects of phytanic acid on the vitamin E status, lipid composition and

... the chain reaction of lipid peroxidation by reacting with lipid peroxyl free radicals, and thus plays an important role in protecting cell membranes from lipid peroxidation. It is, therefore, possible that an accumulation of phytanic acid in tissues and cellular membranes may perturb the function of ...
ELM1 is required for multidrug resistance in
ELM1 is required for multidrug resistance in

... and enzymes involved in lipid and cell wall synthesis (DE R ISI et al. 2000). Similar to Pdr1, several hyperactive Pdr3 activators, including that encoded by the pdr3-2 allele, were identified (NOURANI et al. 1997). The Pdr5 transporter is a major plasma membrane-associated ATPase regulated by Pdr1/ ...
Self-organization and pattern formation in auxin flow
Self-organization and pattern formation in auxin flow

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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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