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Reperfusion of ischemic myocardium: Ultrastructural and
Reperfusion of ischemic myocardium: Ultrastructural and

... with macroscopic differential staining. Occlusion of two small coronary arteries in the same heart followed by reperfusion of only one artery (identical occlusion times for both arteries) showed identical infarct sizes for reperfused and nonreperfused myocardium for occlusion times of 3 and 6 hours. ...
Glucose-dependent, CAMP-mediated ATP efflux from
Glucose-dependent, CAMP-mediated ATP efflux from

... view of the ability of all cells to release cAMP (Brunton & Heasley, 1988), we asked ,whether ATP release is also a feature of unicellular organisms. In this paper we describe experiments which demonstrated ATP efflux from S. cerevisiae. This efflux required glucose and was stimulated by proton iono ...
Vocab smack-down
Vocab smack-down

... • You must keep your voice at a whisper • LISTEN/READ the correct answer on the board for EVERY question… • This game is to help you prepare for the test! • If you cannot keep yourselves under control, you will have an alternative assignment: • Write definitions/characteristics of cell organelles 3 ...
Therapeutic potential of the biscoclaurine alkaloid, cepharanthine
Therapeutic potential of the biscoclaurine alkaloid, cepharanthine

... 35, 36, 38, 49]. It has also been reported to reverse multi-drug resistance [1, 11, 13, 27, 31, 44, 46, 48, 57, 67], and potentiate chemotherapy [8, 26, 54] and display anti-inflammatory effects [16]. Although the mechanisms underlying the action of CEP are not fully understood, they are believed to ...
Functional Architecture in Lateral Line Afferent Neurons.
Functional Architecture in Lateral Line Afferent Neurons.

PDF
PDF

... heterochronic tissue combinations. The results of these experiments support the concept that mesenchymal factors are important for the histogenesis of palatal epithelium and show that palatal epithelium has a potential for limited differentiation in isolation. Brief abstracts of certain aspects of t ...
Constrained transcription factor spacing is prevalent and important
Constrained transcription factor spacing is prevalent and important

... previous step (‘Scanning ChIP-seq peaks for known motifs’) with at least 50 occurrences in the genome were organized by Jaspar ID. By doing this, the motif regions are dissociated from the sample ID and unique coordinates were kept. By iterating over all pairwise combination of motifs, the offset, s ...
Evidence for an Extracellular Reception Site for Abscisic
Evidence for an Extracellular Reception Site for Abscisic

... intensities of known concentrations, between 10 ^M and 20 mM, of carboxyfluorescein were measured in microelectrode tips as above and were used to estimate cytoplasmic carboxyfluorescein concentration following iontophoretic microinjection. This calibration provided a coarse correction for fluoresce ...
Vascular / Endovascular Surgery
Vascular / Endovascular Surgery

... therapy for patients with vascular disease, including cardiology, and more recently vascular medicine. Care of the vascular patient is different than care for patients in most other surgical specialties. In the case of vascular surgery, most cases pose a major risk of significant complications to th ...
Low and High Nucleic Acid Content Bacteria: Reality or
Low and High Nucleic Acid Content Bacteria: Reality or

... two clusters have been given names LNA and HNA bacteria respectively. The majority of studies carried out in this field have focused on the abundance of these HNA and LNA cells in different environments and their relative activity. The main reason for this is a lack of suitable culture methods. Ther ...
Protection of Drosophila chromosome ends through minimal
Protection of Drosophila chromosome ends through minimal

... Fig. 2. hiphop knockdown in the male germline dramatically impairs early spermatogenesis. (A,B) Confocal images showing a pair of testes from a control male (A) and a hiphop knockdown male (B, nos-Gal4/UAS-sh-hiphop), stained with a pan-histone antibody. The scale is the same for both images. Note t ...
Structures of the lymphatic system
Structures of the lymphatic system

... Absorb fats and vitamins from digestive system Return waste products and extra fluid to circulatory system Structures of the lymphatic system: Lymph fluid, lymph vessels, lymphatic capillaries, lacteals, lymph nodes, right lymphatic duct, thoracic duct, cisterna chyli, tonsils, spleen, thymus, ...
Concept of Rakta Dhatu
Concept of Rakta Dhatu

... Dhatu’s. As compared to modern science, which merely describes it as blood, the composition, nature and functions described in the functions of Raktadhatu are very broad and any kind of imbalance in it affects the whole body. Ayurveda covers Raktadhatu in much wider aspect. Ayurvedic texts reveal th ...
Dubrulle and Pourquie, 2004 - Development
Dubrulle and Pourquie, 2004 - Development

... Each cell contributing to the paraxial mesoderm undergoes a series of stereotypical events, from its specification in the caudal part of the embryo to its incorporation into a somite (Fig. 1A). The first step in paraxial mesoderm formation is a change in the cellular adhesion properties. Cells conta ...
Endosomes/Lysosomes in Macrophages Fusion between
Endosomes/Lysosomes in Macrophages Fusion between

... responsible for phagocyte binding to apoptotic cells have been proposed (reviewed in Refs. 4, 12, and 13). Immunity is central to the self-defense mechanism, which can be divided into the innate and adaptive immune responses. Innate immunity is defined as a mechanism by which self and non-self are d ...
Cleavage modification did not alter early blastomere fates
Cleavage modification did not alter early blastomere fates

... bioRxiv preprint first posted online Aug. 11, 2016; doi: http://dx.doi.org/10.1101/068783. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
Full-Text PDF
Full-Text PDF

... INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics, Joseph Fourier University, ...
Maintaining a Balance #7
Maintaining a Balance #7

... - The elastic fibres maintain blood pressure and send blood in spurts towards body tissues via the vessels expanding and recoiling with heartbeat - Carries blood back to heart after passing through the capillaries - Thinner walls, less muscle and larger diameter than of arteries as blood flows at a ...
histology cytology embryology
histology cytology embryology

... differentiation (more often owing to loss of a nucleus and a part of organelles) have lost the major signs of cells, but have got a number of the properties necessary for execution by them the specialized functions. The postcellular structures at human are erythrocytes, platelets, horny cells of epi ...
J., Schornack, S., Spallek, T., Geldner, N., Chory
J., Schornack, S., Spallek, T., Geldner, N., Chory

... stable Arabidopsis transgenic lines (Tables S1 and S2). This suggests a significant level of conservation of the used subcellular markers between Arabidopsis and N. benthamiana making it suitable for a comparative study. We first used fluorescent probes to follow the infection of Hpa in Arabidopsis ...
File
File

... respirometer. Temperature is held constant in the chamber, with air of known O2 concentration flowing through. The crab’s metabolic rate is calculated from the difference between the amount of O2 entering and the amount of O2 leaving the respirometer. This crab is on a treadmill, running b at a cons ...
Cell delamination in the mesencephalic neural fold
Cell delamination in the mesencephalic neural fold

... Epithelial cells are polarized, as revealed by the apical and basal localizations of zona occludens 1 (ZO1; also known as Tjp1) and βdystroglycan (dystroglycan 1), respectively. During EMT, this apical/basal polarization of cells is lost. At 5 somites, when the two neural folds become juxtaposed, we ...
File produced at level 10
File produced at level 10

... organisms. Jodi Nunnari, Wallace Marshall, John Sedat, Peter Walter, and their colleagues at UC San Francisco demonstrated that mitochondrial fusion occurs in the budding yeast Saccharomyces cerevisiae. They treated two live, haploid S. cerevisiae populations with green or red mitochondriaspecific f ...
Conjugated linoleic acid decreases production
Conjugated linoleic acid decreases production

... decreased the interferon-g (IFNg)-induced mRNA expression of mediators of inflammation including cyclooxygenase 2 (COX2), inducible NOS (iNOS), and tumor necrosis factor a (TNFa). Reporter assays also demonstrated reduced IFNg-stimulated transcriptional activity of the iNOS and COX2 promoters by CLA ...
Essentials of Human Physiology for Pharmacy
Essentials of Human Physiology for Pharmacy

... This textbook is designed to provide the fundamentals of human physiology to students of pharmacy and other health sciences. An important goal of this book is to enhance students’ perceptions of the relevance of physiology to pharmacy practice. The book includes important concepts in physiology desc ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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