• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Live cell imaging reveals actin-cytoskeleton
Live cell imaging reveals actin-cytoskeleton

... Luxembourg. 2Plateforme d’Imagerie Cellulaire et Tissulaire PTIBC-IBISA, CNRSUMR 7563 et FR3209. Université de Lorraine, F-54505 Vandoeuvre-lès-Nancy, France. ...
Stationary phase, amino acid limitation and recovery
Stationary phase, amino acid limitation and recovery

... well as bulk mRNA have been shown to increase during starvation in Vibrio sp. S14 (Albertson et al., 1990) and in E. coli (Albertson & Nystrom, 1994). Obviously, growth rate, growth phase and medium composition impact the stabilities of specific transcripts as well as bulk mRNA. Since mRNA degradati ...
BRAIN CCR2 Ly-6C monocytes are crucial for the
BRAIN CCR2 Ly-6C monocytes are crucial for the

... (Boring et al., 1997; Kuziel et al., 1997), there have been numerous publications examining the effects of CCR2 deficiency in a variety of murine models of infectious and autoimmune diseases. In fact, a number of studies indicated that CCR2 and its ligand CCL2 may play a role in the pathogenesis of ...
PDF
PDF

... divide, and can thus be regarded as ‘transit-amplifying cells’, before their fusion with the myotube templates. Another unique feature of these cells is their migration as a ‘swarm’ of closely associated cells, throughout their transit from the wing disc to the muscle templates (Roy and VijayRaghava ...
Introduction - ART
Introduction - ART

... Cells are continuously exposed to diverse external stimuli, ranging from soluble endocrine and paracrine factors to signaling molecules on neighboring cells. The cell must interpret these extracellular signals to produce an appropriate developmental or proliferative response. Receptors of the tyrosi ...
Can Carbon Nanotubes Deliver on Their
Can Carbon Nanotubes Deliver on Their

... with such control over directionality: metallic nanowires are at least an order of magnitude wider than the smallest CNT bundles used as electrodes, and do not display such anisotropy, nor proportional strength and rigidity. Electrical stimulation of the nervous system can attain significant improvem ...
Vibrio cholerae 01 Can Assume a Chlorine
Vibrio cholerae 01 Can Assume a Chlorine

... to rugose morphology. Rugose strains appear to produce an exopolysaccharide that promotes cell aggregation. Reminiscent of the protective effect of biofilms [12], this aggregation may shield individual cells from killing by disinfectants, such as chlorine, or lysis by complement. Vibrios are an impo ...
Cellular function and pathological role of ATP13A2 and related P
Cellular function and pathological role of ATP13A2 and related P

... flippases and 5 P5-type ATPases with unknown substrate specificity (ATP13A1-5). Figure 1 displays the phylogenetic relationship of these 36 human P-type ATPases and their orthologs in key animal model organisms. Many P-type ATPases display broad expression profiles and fulfill many housekeeping func ...
Shaping the metaphase chromosome: coordination of cohesion and
Shaping the metaphase chromosome: coordination of cohesion and

... Further support for this idea comes from the study of Trf4, a novel DNA polymerase (termed pol k) whose mutation leads to partial defects in sister chromatid cohesion in S. cerevisiae.(35) Although it remains to be determined how a DNA polymerase participates in cohesion, one attractive hypothesis i ...
Micronuclei and the Cytoplasm of Growing Tetrahymena Contain a
Micronuclei and the Cytoplasm of Growing Tetrahymena Contain a

... before assaying the activity that remains soluble. All reactions were carried out at 30~ for 30 min before precipitating the reaction products with 20% TCA. Each washed and dried precipitate was dissolved directly in electrophoresis sample buffer and 10% was removed for liquid scintillation counting ...
Nanoscale Architecture of Endoplasmic Reticulum Export Sites and
Nanoscale Architecture of Endoplasmic Reticulum Export Sites and

... most cellular organelles and cytoskeletal systems at high resolution. As discussed below, dual-axis electron tomography (McIntosh et al., 2005) provides a means for solving the z axis resolution problem of classical electron microscopy as well as for producing 3D models of cellular structures with n ...
Organelle Assembly in Yeast: Characterization of
Organelle Assembly in Yeast: Characterization of

... In an effort to identify components of the vacuolar protein sorting apparatus, we recently isolated a number of mutants that exhibit defects in the proper localization and processing of several vacuolar proteins. These vacuolar protein targeting (vpt) mutants were identified using a gene fusion-base ...
Central nervous system recruitment of effector memory CD8 T
Central nervous system recruitment of effector memory CD8 T

... by chemokine-mediated activation and firm adhesion to the endothelium (Engelhardt and Ransohoff, 2005). BBB-endothelial cells and glial cells are an important source of the pro-inflammatory chemokines CCL2/MCP-1, RANTES and CXCL10/IP-10 (Ifergan et al., 2006), which are required for TH1 and TH17 lym ...
Back BIOCHEMISTRY FOR 100 CHECK YOUR ANSWER
Back BIOCHEMISTRY FOR 100 CHECK YOUR ANSWER

... LIFE PROCESSES FOR 100 ...
The Pathogen-Actin Connection: A Platform for Defense Signaling in
The Pathogen-Actin Connection: A Platform for Defense Signaling in

... rearrangement in the genetics, the biochemistry, and the structure of the host cell(s). From the first stages of pathogen perception to the final activation of programmed cell death, host resources are allocated and redirected for the purpose of preventing infection, pathogen proliferation, and diseas ...
Molecular mapping of tyrosine-phosphorylated proteins in focal
Molecular mapping of tyrosine-phosphorylated proteins in focal

... eventually grow and ‘mature’ into focal adhesions (Ballestrem et al., 2001; Clark et al., 1998). Focal complexes are tyrosine phosphorylated and contain paxillin and other focal adhesion components (Nakamura et al., 2000; Zaidel-Bar et al., 2003). To test whether paxillin, FAK and CAS are already ph ...
Kb-Positive role of nitrite-12NoMacros
Kb-Positive role of nitrite-12NoMacros

... – Promoted for individuals over 40 when endogenous NO begins to decline – Daily use shown to increase plasma nitrite and nitrate, and decrease blood tryglycerides ...
AgNO3 - a potential regulator of ethylene activity and plant growth
AgNO3 - a potential regulator of ethylene activity and plant growth

... Figure 1. Ethylene biosynthesis and its influences on various physiological processes. Ethylene is involved in many aspects of the plant life cycle, including plant morphogenesis, defense, flowering, sex expression, embryogenesis, seed germination, root hair development, root nodulation, flower sene ...
Skeletal Muscle
Skeletal Muscle

... muscle cell where it can have an affect on the terminal cisternae. We will cover more about this in the unit on the physiology of muscle contraction. The cytosol is the cytoplasm of the muscle cell. The sarcoplasmic reticulum is the endoplasmic reticulum of the muscle cell. There are sac-like region ...
Multiple Myeloma Patient Handbook
Multiple Myeloma Patient Handbook

... 1. Someone who has been newly diagnosed with myeloma and is wondering what it means and what the future will bring. 2. Those who have been living with myeloma for some time, but would like to refresh their understanding of the disease or fill in any missing pieces. 3. A person who is a family mem ...
Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA
Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA

... first terminating the assembly stage by phosphorylating and inactivating CDC6 and then, as its levels rise in late G1, activating the DNA replication machinery. Reversal of the natural order in which nuclei are exposed to cyclins E and A blocks initiation in vitro (Coverley et al., 2002), highlighti ...
Insulin-Like Growth Factor and Potassium Depolarization Maintain
Insulin-Like Growth Factor and Potassium Depolarization Maintain

... During development of the vertebrate nervous system, approximately half of the neurons that are generated die by a process called “programmed cell death.” This naturally occurring process is mediated by apoptosis, a specific form of programmed cell death that has characteristic morphological and bio ...
ANIMAL MODELS OF SEPSIS: SETTING THE STAGE
ANIMAL MODELS OF SEPSIS: SETTING THE STAGE

... have a place in the treatment of sepsis13. The successful application of such opposite therapies requires that the agent (anti-inflammatory or pro-inflammatory) is delivered at the appropriate stage of sepsis to be beneficial and not harmful to the patient. The ideal treatment for sepsis should ther ...
Requirements for CPC localization during anaphase
Requirements for CPC localization during anaphase

... Figure 4. A model for CPC regulation and its effects in S. cerevisiae. A) Before anaphase the CPC is located at the centromeres. Sli15p is phosphorylated by Cdk1p and Ipl1p, contributing to this localization. The CPC regulates proper chromosome segregation in this phase. B) At the start of anaphase ...
Document
Document

... E. abscesses 71. Because rheumatic conditions streptococci penetrate the body through the tonsils, release toxins and cause destruction in the invasion of cells and inflammation, which usually manifests itself: A. *angina B. tonzilyar abscesses C. retropharyngeal abscesses D. Qatar nasopharyngeal E. ...
< 1 ... 35 36 37 38 39 40 41 42 43 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report