Loss of MicroRNAs in Neural Crest Leads to Cardiovascular
... rise to many cell types, including vascular smooth muscle cells, chondrocytes, melanocytes, and neurons.12 Cranial NCCs, a subset of NCCs, which migrate into 1st and 2nd pharyngeal arches (PAs), give rise to cranial ganglia, the maxilla, and the mandible, as well as muscle and cartilage of the head ...
... rise to many cell types, including vascular smooth muscle cells, chondrocytes, melanocytes, and neurons.12 Cranial NCCs, a subset of NCCs, which migrate into 1st and 2nd pharyngeal arches (PAs), give rise to cranial ganglia, the maxilla, and the mandible, as well as muscle and cartilage of the head ...
Identification of a Novel Gene, CIA6, Required for
... greater than 100 mmol CO2 fixed mg21 chlorophyll h21. However, cia5 and cia6 had affinities for DIC that were 1.5 to two times lower than D66 (Fig. 2A; Table I). Airacclimated cells also exhibited similar maximum rates of photosynthesis, but in contrast, both cia5 and cia6 had an affinity for DIC ap ...
... greater than 100 mmol CO2 fixed mg21 chlorophyll h21. However, cia5 and cia6 had affinities for DIC that were 1.5 to two times lower than D66 (Fig. 2A; Table I). Airacclimated cells also exhibited similar maximum rates of photosynthesis, but in contrast, both cia5 and cia6 had an affinity for DIC ap ...
Direct binding of Nur77/NAK-1 to the plasminogen activator inhibitor
... Chapman2). It functions as a serine protease inhibitor (SERPIN) by forming stable 1:1 stochiometric complexes3 with its target proteases that are removed by scavenger receptors.4 PAI-1 regulates intravascular fibrinolysis and tissue proteolysis, and thereby controls thrombus dissolution as well as i ...
... Chapman2). It functions as a serine protease inhibitor (SERPIN) by forming stable 1:1 stochiometric complexes3 with its target proteases that are removed by scavenger receptors.4 PAI-1 regulates intravascular fibrinolysis and tissue proteolysis, and thereby controls thrombus dissolution as well as i ...
Development and Characterization of New Species Cross
... Abstract: Sialoadhesin (Sn) is a surface receptor expressed on a subset of macrophages in steady state conditions. During inflammation and diseases, Sn is highly upregulated on macrophages and blood monocytes. Therefore, therapies using monoclonal antibodies (mAbs) to target Sn-positive (Sn+ ) cells ...
... Abstract: Sialoadhesin (Sn) is a surface receptor expressed on a subset of macrophages in steady state conditions. During inflammation and diseases, Sn is highly upregulated on macrophages and blood monocytes. Therefore, therapies using monoclonal antibodies (mAbs) to target Sn-positive (Sn+ ) cells ...
Functions of mammalian microRNA in innate immunity to microbial
... Ligation of PAMPs to highly specific PRRs on the surface or in the cytoplasm of host cells ...
... Ligation of PAMPs to highly specific PRRs on the surface or in the cytoplasm of host cells ...
Energetic Crosstalk Between Organelles
... oxygen consumption, and caffeine-induced tension transients. The results show that in hearts of normal mice, ATP produced by mitochondria (supplied with substrates, oxygen, and adenine nucleotides) was able to sustain calcium uptake and contractile speed. Moreover, direct mitochondrially supplied AT ...
... oxygen consumption, and caffeine-induced tension transients. The results show that in hearts of normal mice, ATP produced by mitochondria (supplied with substrates, oxygen, and adenine nucleotides) was able to sustain calcium uptake and contractile speed. Moreover, direct mitochondrially supplied AT ...
MCB 3020L Lab Experiment 6 Differential and Cytological Stains A
... Bacterial endospores are resistant to most staining procedures and appear as clear areas in the Gram stain. Poly-beta hydroxybutyrate (bacterial fat) and other intracellular inclusions can also not stain in the Gram stain and appear as clear areas. The spore stain allows you to clearly demonstrate t ...
... Bacterial endospores are resistant to most staining procedures and appear as clear areas in the Gram stain. Poly-beta hydroxybutyrate (bacterial fat) and other intracellular inclusions can also not stain in the Gram stain and appear as clear areas. The spore stain allows you to clearly demonstrate t ...
Energetic Crosstalk Between Organelles
... oxygen consumption, and caffeine-induced tension transients. The results show that in hearts of normal mice, ATP produced by mitochondria (supplied with substrates, oxygen, and adenine nucleotides) was able to sustain calcium uptake and contractile speed. Moreover, direct mitochondrially supplied AT ...
... oxygen consumption, and caffeine-induced tension transients. The results show that in hearts of normal mice, ATP produced by mitochondria (supplied with substrates, oxygen, and adenine nucleotides) was able to sustain calcium uptake and contractile speed. Moreover, direct mitochondrially supplied AT ...
Lipid II: A central component in bacterial cell wall synthesis and a
... rapid. Studies using model membranes demonstrated that translocation across a lipid bilayer is extremely slow and, in contrast to membrane phospholipids, is not stimulated by the presence of transmembrane helices [21], suggesting a more specific proteinmediated mechanism that is involved in phospholi ...
... rapid. Studies using model membranes demonstrated that translocation across a lipid bilayer is extremely slow and, in contrast to membrane phospholipids, is not stimulated by the presence of transmembrane helices [21], suggesting a more specific proteinmediated mechanism that is involved in phospholi ...
The GDP-bound form of Arf6 is located at the plasma membrane
... implicated in endocytosis and actin rearrangements at the cell periphery (Chavrier and Goud, 1999) but its precise function remains to be discovered. Two mutants of Arf6, Q67L and T27N, are considered to mimic the GTP- and GDP-bound forms, respectively, and have been used extensively to apprehend th ...
... implicated in endocytosis and actin rearrangements at the cell periphery (Chavrier and Goud, 1999) but its precise function remains to be discovered. Two mutants of Arf6, Q67L and T27N, are considered to mimic the GTP- and GDP-bound forms, respectively, and have been used extensively to apprehend th ...
Chemotactic Effect of Ciliary Neurotrophic Factor on Macrophages in
... iliary neurotrophic factor (CNTF) has been known to protect neurons via Janus kinase signal transducer and activators of transcription-3 (JAK-STAT3) signaling pathway.1– 4 We have shown that CNTF is a potent neurotrophic factor for retinal ganglion cell (RGC) survival and axonal regeneration after o ...
... iliary neurotrophic factor (CNTF) has been known to protect neurons via Janus kinase signal transducer and activators of transcription-3 (JAK-STAT3) signaling pathway.1– 4 We have shown that CNTF is a potent neurotrophic factor for retinal ganglion cell (RGC) survival and axonal regeneration after o ...
Grape berry vacuole: a complex and heterogeneous membrane
... AJEV Papers in Press are peer-reviewed, accepted articles that have not yet been published in a print issue of the journal or edited or formatted, but may be cited by DOI. The final version may contain substantive or nonsubstantive changes. ...
... AJEV Papers in Press are peer-reviewed, accepted articles that have not yet been published in a print issue of the journal or edited or formatted, but may be cited by DOI. The final version may contain substantive or nonsubstantive changes. ...
A Study of Specificity of Cores for Group D Streptococci
... were dehydrated in ice-cold absolute ethanol for I o min., stained in ice-cold U02(CH3C00), .2H20 in absolute ethanol, I yo (w/v), for 30 min., then dehydrated further in ice-cold absolute ethanol for 10 min. and during the succeeding 50 min. by three changes at room temperature of absolute ethanol ...
... were dehydrated in ice-cold absolute ethanol for I o min., stained in ice-cold U02(CH3C00), .2H20 in absolute ethanol, I yo (w/v), for 30 min., then dehydrated further in ice-cold absolute ethanol for 10 min. and during the succeeding 50 min. by three changes at room temperature of absolute ethanol ...
Nonhereditary p53 Mutations in T-cell Acute
... (37.5Y0) whose disease was refractory t o the reinduction of remission by chemotherapy possessed missense mutations of the p53 gene. All 3 caseshad mutationsin exon 5. Among the paired samples, 3 of 6 patients harbored p53 mutations at disease recurrence, but possessed only wild-type p53 alleles at ...
... (37.5Y0) whose disease was refractory t o the reinduction of remission by chemotherapy possessed missense mutations of the p53 gene. All 3 caseshad mutationsin exon 5. Among the paired samples, 3 of 6 patients harbored p53 mutations at disease recurrence, but possessed only wild-type p53 alleles at ...
Live cell imaging reveals actin-cytoskeleton
... Luxembourg. 2Plateforme d’Imagerie Cellulaire et Tissulaire PTIBC-IBISA, CNRSUMR 7563 et FR3209. Université de Lorraine, F-54505 Vandoeuvre-lès-Nancy, France. ...
... Luxembourg. 2Plateforme d’Imagerie Cellulaire et Tissulaire PTIBC-IBISA, CNRSUMR 7563 et FR3209. Université de Lorraine, F-54505 Vandoeuvre-lès-Nancy, France. ...
Full Text - The International Journal of Developmental Biology
... would shake its foundations. Indeed the radical shift of emphasis to the cellular and subcellular levels and, from the 1950’s on, to the molecular level, transformed experimental embryology to developmental biology”. The term “decline” of experimental embryology was falsely interpreted by some autho ...
... would shake its foundations. Indeed the radical shift of emphasis to the cellular and subcellular levels and, from the 1950’s on, to the molecular level, transformed experimental embryology to developmental biology”. The term “decline” of experimental embryology was falsely interpreted by some autho ...
The Physiological Significance of Mitochondrial Proton Leak in
... compared to euthyroid controls (Harper & Brand, 1993). The proton permeability of mitochondria isolated from liver is 7-fold greater in hyperthyroid rats compared with those from hypothyroid animals (Hafner el al., 1988). The lower oxygen consumption rates of liver cells isolated from hypothyroid ra ...
... compared to euthyroid controls (Harper & Brand, 1993). The proton permeability of mitochondria isolated from liver is 7-fold greater in hyperthyroid rats compared with those from hypothyroid animals (Hafner el al., 1988). The lower oxygen consumption rates of liver cells isolated from hypothyroid ra ...
Interaction of PIN and PGP transport mechanisms in auxin
... Important questions in auxin research relate to the roles of these two types of auxin efflux proteins in auxin transport. Do they represent independent mechanisms? What would be the functional requirements for two distinct transport systems? Do they cooperate and how? The only partial colocalization ...
... Important questions in auxin research relate to the roles of these two types of auxin efflux proteins in auxin transport. Do they represent independent mechanisms? What would be the functional requirements for two distinct transport systems? Do they cooperate and how? The only partial colocalization ...
... calcium, dental materials, drug delivery agent, gene carriers biology, adsorbent of liquid chromatography and proteins, catalysts, ion exchangers, removal of organic pollutants like phenol and other divalent metal cations, gas sensors, proton conductors and more [4,5]. However, bacterial contaminati ...
235 actions of bicuculline on cell body and neuropilar membranes of
... neuronal nicotinic receptors on this cell differ from both peripheral and central vertebrate cholinergic receptors. For example, this insect nicotinic receptor is blocked by both abungarotoxin (Sattelle, 1985, 1986) and k-bungarotoxin (Chiappinelli et al. 1989; Pinnock et al. 1988), and is relativel ...
... neuronal nicotinic receptors on this cell differ from both peripheral and central vertebrate cholinergic receptors. For example, this insect nicotinic receptor is blocked by both abungarotoxin (Sattelle, 1985, 1986) and k-bungarotoxin (Chiappinelli et al. 1989; Pinnock et al. 1988), and is relativel ...
ABSTRACT Title of Dissertation: GENETIC REGULATION OF AUTOPHAGIC CELL... Sudeshna Dutta, Doctor of Philosophy, 2008
... Programmed cell death was initially defined as a series of events that finally leads to the death of a cell (Lockshin and Williams, 1965). This descriptive definition of programmed cell death was validated when it was shown that genes are required for this process, and that they can be placed into a ...
... Programmed cell death was initially defined as a series of events that finally leads to the death of a cell (Lockshin and Williams, 1965). This descriptive definition of programmed cell death was validated when it was shown that genes are required for this process, and that they can be placed into a ...
Modeling Root Zone Effects on Preferred Pathways for the Passive
... et al. (2015) developed models of the uptake of zinc and silicon, respectively, in the DZ. Their efforts focused on the radial distribution of these solutes (including the effects of apoplastic transport barriers) and as a result they did not consider any variations in transport properties along the ...
... et al. (2015) developed models of the uptake of zinc and silicon, respectively, in the DZ. Their efforts focused on the radial distribution of these solutes (including the effects of apoplastic transport barriers) and as a result they did not consider any variations in transport properties along the ...
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... we perturbed Gαo activity in the synapse. Gαo was modulated by the presynaptic expression of two previously tested UAS constructs: RNAi-Gαo, which downregulates Gαo (Purvanov et al., 2010) (see supplementary material Fig. S1I-K for the efficiency of downregulation); and Gαo[Q205L], which is a consti ...
... we perturbed Gαo activity in the synapse. Gαo was modulated by the presynaptic expression of two previously tested UAS constructs: RNAi-Gαo, which downregulates Gαo (Purvanov et al., 2010) (see supplementary material Fig. S1I-K for the efficiency of downregulation); and Gαo[Q205L], which is a consti ...
Identification and Characterization of the Acid Phosphatase HppA in
... agent of gastric diseases and/or carcinomas [19, 20]. H. pylori apparently favors neutral pH for growth, but it resides in extremely low pH conditions, which results from the presence of gastric acid or the occasional acid shocks that occur when the gastric mucus layer is damaged [31, 32]. It is sti ...
... agent of gastric diseases and/or carcinomas [19, 20]. H. pylori apparently favors neutral pH for growth, but it resides in extremely low pH conditions, which results from the presence of gastric acid or the occasional acid shocks that occur when the gastric mucus layer is damaged [31, 32]. It is sti ...
Upregulation of Alveolar Epithelial Active Na Transport Is
... transport is unknown. In this study, we report that mice with no 1- or 2-adrenergic receptors (1AR⫺/⫺/2AR⫺/⫺) have reduced distal lung Na,K-ATPase function and diminished basal and amiloride-sensitive AFC. Total lung water content in these animals was not different from wild-type controls, sugge ...
... transport is unknown. In this study, we report that mice with no 1- or 2-adrenergic receptors (1AR⫺/⫺/2AR⫺/⫺) have reduced distal lung Na,K-ATPase function and diminished basal and amiloride-sensitive AFC. Total lung water content in these animals was not different from wild-type controls, sugge ...