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SRF - Journal of Cell Science
SRF - Journal of Cell Science

Contract Monoclonal Antibody Production
Contract Monoclonal Antibody Production

What does cell division do for an organism
What does cell division do for an organism

... What does cell division do for an organism? ...
A Late Mitotic Regulatory Network Controlling
A Late Mitotic Regulatory Network Controlling

... Shirayama et al., 1998). Similar evidence suggests that HCT1 promotes the destruction of Clb2 and Ase1 but not that of Pds1 (Schwab et al., 1997; Visintin et al., 1997). The regulation of these putative specificity factors is not well understood, although recent studies suggest that Cdc20 may be reg ...
Microbial Cell Factories
Microbial Cell Factories

... progressively developed [4-19]. In parallel, mammalian and insect cells for the production of high quality proteins, and other microbial species appealing from an industrial point of view due to their unusual physiological traits, have been incorporated to the cell factory family [20,21]. This comp ...
Emerging LCDs Based on the Kerr Effect - Prof. Shin
Emerging LCDs Based on the Kerr Effect - Prof. Shin

... Kerr effect, Fig. 3 shows the simulated V–T curves for cells in different W/L ratios (electrode width W to spacing width L), cell gaps, and Kerr constants (K1 = 12.7 nm/V2 and K2 = 10K1). Generally speaking, the cell gap affects the transmittance and response time in a conventional IPS cell. However ...
chapter 1 slides - Mrs. Brenner`s Biology
chapter 1 slides - Mrs. Brenner`s Biology

... • All living organisms must reproduce to maintain a population. • The manner of reproduction varies among different organisms. • When organisms reproduce, they pass on copies of their genetic information (genes) to the next generation.  Genes determine the characteristics of an organism.  Genes ar ...
D:\ACTA\3-2003\jozwiak 732.vp
D:\ACTA\3-2003\jozwiak 732.vp

... obtained from commercial sources. Cell culture. C-2 and C-5 are cell lines derived from the skin of diabetic patients type II, and S-126 cell line from the skin of a normal donor. They were obtained from the tissue bank of the Centre of Child Health (Warsaw, Poland). Cells were cultured as monolayer ...
Division of Clinical and Experimental Oncology Department of
Division of Clinical and Experimental Oncology Department of

... this viewpoint, deletion of the long arm of chromosome 7 is very important because this is not only one of the most frequently detected chromosomal abnormalities found in sporadic myeloid leukemia and myelodysplastic syndrome (MDS), but also strongly implicated in radiation-induced myeloid malignanc ...
Progressive divergence of definitive haematopoietic stem cells from
Progressive divergence of definitive haematopoietic stem cells from

... expressed KIT. However, in contrast to both the endothelial and haematopoietic lineages, this fraction was greatly enriched for KIThigh cells. Unlike the haematopoietic population, all endothelial and DP cells expressed low levels of SCA1. AA4.1 and CD34, also associated with the embryonic HSCs phen ...
Role of E-cadherin and other cell adhesion molecules in survival
Role of E-cadherin and other cell adhesion molecules in survival

... Figure 1 (See opposite page). E-cadherin and its associated molecules in the survival and differentiation of human embryonic stem cells. (A) The molecular structure and the binding sites of E-cadherin and its connection with actin cytoskeleton. The extracellular region of E-cadherin consists of five ...
Isolated Organ Perfusion Does Not Result in - Bio
Isolated Organ Perfusion Does Not Result in - Bio

... ILP. Patients 1, 3, and 6 had no evidence of disease progression after treatment. In contrast, Patients 2, 4, and 5 developed both tumor progression and distant metastases within months after treatment. Patient 2 developed lung metastases after IHP for colon metastases to the liver. Patient 4 had di ...
Tissue:
Tissue:

... – All epithelia exhibit polarity where the cells near the apical surface differ from those at the basal surface – Apical surfaces can be smooth, most have microvilli, and some have cilia – The basal surface of epithelium is called the basal lamina, which acts as a selective filter that determines wh ...
The lipid phosphatase LPP3 regulates extra
The lipid phosphatase LPP3 regulates extra

... are glycoproteins with a channel-like structure containing six putative transmembrane domains (Kanoh et al., 1997) and were first characterized from their ability to dephosphorylate phosphatidic acid (PA) to produce diacylglycerol (DAG). Since PA and DAG act as potent signaling molecules, LPPs play ...
GNOM-LIKE1/ERMO1 and SEC24a/ERMO2 Are
GNOM-LIKE1/ERMO1 and SEC24a/ERMO2 Are

... and Walz, 2001). The outer nuclear envelope is continuous with the rough ER, and the rough ER is distinguished from smooth ER by the presence of ribosomes on the cytosolic side of the membrane. The ER forms a dynamic polygonal network composed of tubules, sheets, and three-way junctions. In addition ...
What you need to know about stem cell therapies
What you need to know about stem cell therapies

... innovation There are also types of studies that fall outside the usual clinical trial framework. Medical innovation is when a doctor treats a small number of very ill patients because there is a scientific reason to do so based on preclinical studies showing safety and efficacy, and the doctor think ...
Understanding the role of cholesterol in cellular biomechanics and
Understanding the role of cholesterol in cellular biomechanics and

... of proteins and receptors with rafts could regulate many of these functions. Rafts might then be seen as platforms that concentrate receptors in a new microenvironment, whose functions are protected from non-raft enzymes, as is the case for phosphatases that could affect signaling processes [93]. 2. ...
Characterization of the unconventional myosin VIII in plant cells and
Characterization of the unconventional myosin VIII in plant cells and

... which, in association with actin, are involved in intracellular motile processes. In addition to the conventional myosins involved in muscle contractility, there is, in animal cells, a wide range of unconventional myosins implicated in membrane-associated processes, such as vesicle transport and mem ...
Biodiversity: Life in a Drop of Water
Biodiversity: Life in a Drop of Water

... green, flagella (whip-like cilia), freeswimming, red eye spot, body is flexible <0.4 mm ...
Fibronectins Are Essential for Heart and Blood Vessel
Fibronectins Are Essential for Heart and Blood Vessel

... IBRONECTINS (FNs) are major components of the extracellular matrix and blood plasma, and are specific ligands for several integrin adhesion receptors.1-3 In vitro, FNs have been shown to function in cell adhesion, migration, and extracellular matrix assembly.4,5 Wide expression of FNs in vivo sugges ...
A Role for Eosinophils in Adaptive Humoral Immunity
A Role for Eosinophils in Adaptive Humoral Immunity

... Department of Pathology and Laboratory Medicine, UMDNJ - New Jersey Medical School, Newark, NJ, USA Abstract: This review describes eosinophils in the context of their conspicuous presence as part of the memory (i.e., anamnestic) immune response to antigen. We propose a role for eosinophils, along w ...
Tissue Culture
Tissue Culture

... Why do Plant Tissue Culture, II • In plants prone to virus diseases, virus free explants (new meristem tissue is usually virus free) can be cultivated to provide virus free plants • Plant ‘tissue banks’ can be frozen, then regenerated through tissue culture • Plant cultures in approved media are ea ...
Role of - Molecular Physiology and Biophysics
Role of - Molecular Physiology and Biophysics

... the rLNa2G-mediated M. leprae–a-DG interaction showed that this binding is completely abolished by EDTA, indicating the crucial role of calcium for the interaction of the G domain with a-DG. Moreover, the lack of inhibitory effects of heparin on rLNa2Gmediated M. leprae binding to a-DG (Fig. 2E) sug ...
PDF
PDF

... and salivary glands of the vector, the tsetse fly. Many basic biological processes like motility, energy metabolism and morphology have to be adapted during several developmental differentiation events in order to survive and proliferate in these different environments (reviewed in [2,3]). Trypanoso ...
Nitrogen gas flushing can be bactericidal: the temperature
Nitrogen gas flushing can be bactericidal: the temperature

... and 25◦ C. Bacillus weihenstephanensis, a frequent inhabitant of fluid dairy products, is represented by the genome-sequenced KBAB4 strain. Among Pseudomonas, P. tolaasii LMG 2342T and strain C1, a raw milk psychrotroph, were selected. The N2 gas flushing treatment revealed: (1) temperature-dependen ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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