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Herpes simplex virus type 1 alters transcript levels of tumor
Herpes simplex virus type 1 alters transcript levels of tumor

... subsequent resolution of immune and/or inflammatory responses to a variety of pathogens. These multifunctional soluble mediators are produced locally and act either in an autocrine or a paracrine manner. The cytokine balance during a host immune response to an infectious agent influences whether the ...
University of Groningen Carbohydrate production by
University of Groningen Carbohydrate production by

... Alternatively, there may be a different type of glucan produced by colonial Phaeocystis cells. If there is another type of storage glucan besides chrysolaminaran, it is not clear if this is located in the cells or in the colony matrix. In all plants photosynthetic rates exceed metabolic demands when ...
Journal of Cell Science • Advance article Rop, the
Journal of Cell Science • Advance article Rop, the

... RopA19/G11 males generated embryos with three different zygotic genotypes—homozygous RopA19, homozygous RopG11, and heteroallelic RopA19/G11. Because we could not distinguish between these zygotic genotypes by genetic markers, we call the genotype of this collection of embryos as RopTS (for their te ...
Zebrafish germ cell migration - Development
Zebrafish germ cell migration - Development

... all stages analyzed, including extension of numerous cellular processes (Fig. 3G-I, Movie 2 on-line). The migration patterns are highly dynamic: individual PGCs frequently change their speed, direction and position relative to each other during migration (see Fig. 1, Fig. 2, Fig. 3, and Movies 1 and ...
Modulation of oxidative stress as an anticancer strategy
Modulation of oxidative stress as an anticancer strategy

... increase antioxidant expression and reduce ROS levels21. ROS are also involved in normal stem cell renewal and differentiation22. Although cancer stem cells (also known as tumour-initiating cells; TICs) share similar phenotypes with normal stem cells, relatively little is known about their redox sta ...
Eating
Eating

... blood and excites neural circuits that initiate drinking. ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... The Kv1.5 channel has been shown to be located at the IDs of atrial cells when visualised with MeOH fixation [3]. Regarding other results using FA and MeOH fixation (Table 1), Kv4.2 at the IDs and Cav1.2 at the t-tubules were not detected by FA but were detected by MeOH. Kv4.2 is responsible for tra ...
Macrophage-specific gene functions in Spi1
Macrophage-specific gene functions in Spi1

Electricity-producing bacterial communities in microbial fuel cells
Electricity-producing bacterial communities in microbial fuel cells

... treatment and as power sources for environmental sensors. The power produced by these systems is currently limited, primarily by high internal (ohmic) resistance. However, improvements in the system architecture will soon result in power generation that is dependent on the capabilities of the microo ...
Transient Exposure to Ethylene Stimulates Cell Division and Alters
Transient Exposure to Ethylene Stimulates Cell Division and Alters

... Most of ethylene’s known effects on plant development have been observed during continuous ethylene treatments. We wanted to examine the consequence of transient exposure to ethylene, and therefore documented the structural changes that took place following exposure to exogenous ethylene. We chose t ...
Role of the RNA-binding protein Roquin in immune homeostasis
Role of the RNA-binding protein Roquin in immune homeostasis

... domain by introducing a positively charged arginine residue, but it does not destabilize the protein, since normal levels of Roquin have been detected by western blot in ex vivo isolated san/san thymocytes [5]. The analysis of the sanroque mouse strain revealed the critical function of Roquin and it ...
Inducible depletion of adult skeletal muscle stem cells impairs the
Inducible depletion of adult skeletal muscle stem cells impairs the

AMPK regulates ER morphology and function in
AMPK regulates ER morphology and function in

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative
Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative

... Phase I and II enzymes are involved in the metabolism of endogenous reactive compounds as well as xenobiotics, including toxicants and drugs. Genotyping studies have established several drug metabolizing enzymes as markers for risk of drug hypersensitivity. However, other candidates are emerging tha ...
A virus`s
A virus`s

... desk, to be checked for completion. • Place Bacteria Structure Drawing on desk. • Turn in Virus & Bacteria HW Handout ...
Negative feedback control of the autoimmune
Negative feedback control of the autoimmune

... foreign and self-antigens (Moore et al., 2001) that are primarily mediated by its inhibitory activities on the function of APCs (de Waal Malefyt et al., 1991). Although the role of IL-10 in suppression of experimental autoimmune encephalomyelitis in the Tg4 model is not known, the effect of IL-10 on ...
Conserved functions of retinoblastoma proteins: From purple retina
Conserved functions of retinoblastoma proteins: From purple retina

... sites can be accounted for by the activity of cyclin-dependent kinases (CDKs). Hypophosphorylated, active forms of pRB dominate in G1, whereas, hyperphosphorylated forms appear as cells enter S phase and dominate in G2 and M phases [33]. Results of phosphopeptide analyses of pRB suggest more than a ...
Steel Factor Induces Serine Phosphorylation of
Steel Factor Induces Serine Phosphorylation of

Cilia Review Article - Eastern Virginia Medical School
Cilia Review Article - Eastern Virginia Medical School

... Work with C. elegans provided early clues that the gene products for PKD1 and PKD2 might also be involved with cilia structure and/or function. During the examination of mutations that affect mating behavior in C. elegans, Barr et al. (1999, 2001) identified worm homologs of PKD1 as lov-1 (for locat ...
CYTOKINESIS IN HIGHER PLANTS
CYTOKINESIS IN HIGHER PLANTS

... cytokinesis of male meiotic cells in Arabidopsis was recently shown to resemble somatic cytokinesis in one important aspect—delivery of membrane vesicles to the plane of division and formation of membrane networks generated by vesicle fusion across the division plane, which contrasts with the previo ...
Report into the death of Prisoner D 2016
Report into the death of Prisoner D 2016

A CDC45 Homolog in Arabidopsis Is Essential for Meiosis, as
A CDC45 Homolog in Arabidopsis Is Essential for Meiosis, as

... and in Xenopus, immunodepletion of CDC45 prevents DNA polymerase  loading onto chromatin (Mimura and Takisawa, 1998). CDC45 may play both a temporal and a checkpointmediated role in the regulation of replication origins, because its binding to late origins has been shown to be delayed relative to e ...
PDF
PDF

... growth factor receptor (Egfr) mutant mice suffer from multiorgan failure due to widespread impairment of epithelial development (Miettinen et al., 1995), and mice with reduced levels of one Egfr ligand, transforming growth factor α (TGFα), share some of these developmental abnormalities (Luetteke et ...
Conditional lethality of a yeast strain expressing human RHOA in place of RHO1 .
Conditional lethality of a yeast strain expressing human RHOA in place of RHO1 .

... YOC725 cells stop growing after -6 h, but the bud sizes appear to be random. Flow cytometric analysis (data not shown) further confirms that the cells stop growing at all stages of the cell cycle. Since many cells looked fragile under the microscope, we tested an effect of osmotic stabilizer on thei ...
PDF
PDF

... that are regulated during murine WAT development in vivo. By using a de novo cis-regulatory motif discovery tool (FIRE), we identify two early gene clusters whose promoters show significant enrichment for NRF2/ETS transcription factor binding sites. We further demonstrate that Ets transcription fact ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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