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Synergistic interaction between C5a and NOD2 signaling
Synergistic interaction between C5a and NOD2 signaling

... The innate immune response is a complex process involving multiple pathogen-recognition receptors, including toll-like receptors (TLRs) and nucleotidebinding oligomerization domain (NOD)-like receptors. Complement is also a critical component of innate immunity. While complement is known to interact ...
Autophagic Components Contribute to Hypersensitive Cell Death in
Autophagic Components Contribute to Hypersensitive Cell Death in

Alleati per un`antropologia positiva Scienza e Vita in dialogo con AIOM
Alleati per un`antropologia positiva Scienza e Vita in dialogo con AIOM

... di risposta Paolo Marchetti ...
Document
Document

... is a protective layer that covers the cell’s surface and acts as a barrier. • Inside the cell is a fluid. This fluid and almost all of its contents are called cytoplasm. ...
Identification of the Protein Storage Vacuole
Identification of the Protein Storage Vacuole

... These studies clearly demonstrate that multiple types of vacuoles occur not only in a single plant species but also in a single cell. The biological roles of the lytic vacuole present in most cells and PSVs in seed cells are rather clear (Herman and Larkins, 1999; Marty, 1999). The lytic vacuole is ...
Simple microwave field imaging technique using hot atomic vapor
Simple microwave field imaging technique using hot atomic vapor

Xyloglucan Endotransglycosylases Have a Function
Xyloglucan Endotransglycosylases Have a Function

... xylem cells were labeled during their radial expansion, but surprisingly, more intense labeling was associated with xylem fibers during their secondary wall thickening (Figures 1D and 1F). The activity assay results indicated a function for XET in several tissues and cell types of the poplar stem, s ...
Membrane Bistability in Olfactory Bulb Mitral Cells
Membrane Bistability in Olfactory Bulb Mitral Cells

... remain unclear. The present study therefore further investigated the membrane properties of mitral cells. The results show that mitral cells are bistable, maintaining two levels of membrane potential with different responsiveness to ON input. Active properties of the mitral cell membrane, operating ...
Functional Utrastructure of Genlisea (Lentibulariaceae) Digestive
Functional Utrastructure of Genlisea (Lentibulariaceae) Digestive

... which divides into two helically twisted arms (Fig. 1A). The digestive hairs have the same simple architecture consisting of three functional compartments: basal cell, middle cell, and a large head formed of four to eight terminal secretory cells (Goebel, 1891; Lloyd, 1942; Reut, 1993; Płachno, 2006 ...
MIMOSA PUDICA L. A SENSITIVE PLANT ABSTRACT Keyword
MIMOSA PUDICA L. A SENSITIVE PLANT ABSTRACT Keyword

... early during ontogenetic differentiation), and the second is a longer and narrower type (having a persistent nucleus with one or two nucleoli and cytoplasm). It is generally accepted that the normal function of the sieve tube element is for the transport of solutes along the longitudinal axis of the ...
Ultrastructure of diaphragm from dystrophic α-sarcoglycan
Ultrastructure of diaphragm from dystrophic α-sarcoglycan

... muscle fibres, we identified a discrete number of heterogeneous cells, large areas containing fields of irregularly arranged collagen fibrils (Fig. 2), split muscle fibre fragments and cell remnants. Some of the interstitial cells were identified as fibroblasts, leukocytes, lymphocytes, or mast cells, cell ...
Genome-wide analysis of the sox family in the calcareous
Genome-wide analysis of the sox family in the calcareous

... [8,9] and placozoans (Trichoplax adhaerens) [10], they have likely arisen in the last common ancestor to the Metazoa [8]. There is a larger repertoire of Sox genes in cnidarians [11-13] and the ctenophore Pleurobrachia pileus [14] than in the demosponges [8,9,15] and the placozoans [10]. Previous ph ...
Roots, Stems, Leaves Notes PPT
Roots, Stems, Leaves Notes PPT

... tips of the roots and stems. These cells are produced in meristems. ...
Luciferase reporter assays: Powerful, adaptable tools for cell biology
Luciferase reporter assays: Powerful, adaptable tools for cell biology

... investigating questions that involve gene regulation. Here we demonstrate how luciferase technology can be a powerful tool in your research program across a wide area of focus. Bioluminescence encompasses a number of different chemistries evolved for light production and is based on the interaction ...
Monomeric alpha-catenin links cadherin to the actin cytoskeleton
Monomeric alpha-catenin links cadherin to the actin cytoskeleton

... interacted with Arm in embryonic lysate immunoprecipitates whereas, as expected, αCat1VH1 did not (Fig. 1b). Together, our findings suggest that the α-Cat VH1 and VH3 regions are essential for adherens junction formation. In contrast, the α-Cat CTD is dispensable for α-Cat function in the follicular ...
Monoclonal antibody 7G3 recognizes the N
Monoclonal antibody 7G3 recognizes the N

... that stimulates production of hematopoietic cells from multiple lineages, including neutrophils, eosinophils, monocytes, megakaryocytes, erythroid cells, basophils, and B cells.'-6 Recently, IL-3 has also been shown to regulate vascular endothelial cell functions, enhancing adhesion molecule express ...
Hallmarks of epithelial to mesenchymal transition are detectable in
Hallmarks of epithelial to mesenchymal transition are detectable in

... translocates into the nucleus and initiates the expression of EMT-associated genes, such as αSMA, vimentin or TGFβ [18,19]. TGFβ has been shown to regulate expression and activity of the Snail transcription factor family member, SLUG, via β-catenin in epithelial cell systems and SLUG has also be ...
The nucleolus through the years
The nucleolus through the years

... RNA’s transcribed in the nucleolus. Further studies in this direction agreed with such speculation. Moreover, according to recent studies nucleoli possess other RNA species including messenger, transfer and especially small RNA’s. It is known that several small nucleolar RNAs participate in ribosoma ...
ii. synthetic analogues to target the membrane ci-m6pr - HAL
ii. synthetic analogues to target the membrane ci-m6pr - HAL

... and die peri-natally [30-32]. As this phenotype can be reversed by a deficiency in IGF-II, it is directly caused by the over-expression of IGF-II. In humans, the soluble levels of CI-M6PR in serum are higher in infants and fall by 40% in adult life to reach a circulating level of about 700 µg/l [33, ...
Sample pages 1 PDF
Sample pages 1 PDF

... model systems, but AP-4 appears to have some role in Golgi to lysosome trafficking (Barois and Bakke 2005) and basolateral redirection (Simmen et al. 2002), although its function has not been demonstrated. The Arabidopsis genome encodes orthologs of animal clathrin-mediated vesicular trafficking pro ...
Recurrent ETNK1 mutations in atypical chronic
Recurrent ETNK1 mutations in atypical chronic

... (Suppl. Fig. 1b). No fusions or recurrent copy number abnormalities were detected. The evidence of recurrent, somatic ETNK1 mutations has never been reported in cancer, suggesting that these variants could be restricted to aCML and, possibly, to closely related clonal diseases. Targeted resequencing ...
Structure and Function of Plant Cell Wall Proteins
Structure and Function of Plant Cell Wall Proteins

... have now reported the existence of nuclear trans-acting factors that interact with specific cis-acting elements of the carrot extensin gene promoter in a wound-specific and ethylenespecific fashion (Holdsworth and Laties, 1989a, 1989b; Granel1 et al., 1992). Similarly, Wycoff et al. (1991) have carr ...
Lysosomes and Fas-mediated liver cell death
Lysosomes and Fas-mediated liver cell death

... in vivo in the Fas apoptotic pathway may be of some help to explore specific therapeutic targets for cell death inhibition in these pathologies [4–6]. Until now, results published on the possible involvement of lysosomes in Fas-induced apoptosis have been mostly obtained ex vivo and are controversia ...
Protein phosphatases and the regulation of mitosis
Protein phosphatases and the regulation of mitosis

... division. We will therefore focus on this second main group of phosphatases, the serine/threonine-specific phosphatases (PSTPs), and their many roles in mitosis and cytokinesis. PSTPs can be further subdivided into the PPM family of metallo-dependent phosphatases (including PPM1) and the phospho-pro ...
HIV-1 Evolves into a Nonsyncytium-Inducing Virus upon Prolonged
HIV-1 Evolves into a Nonsyncytium-Inducing Virus upon Prolonged

... loss of infectivity on the other cell lines. Although speculative, these differences may be relevant for discerning the mechanism(s) behind each phenotype. Env mutations do not change the coreceptor usage The T-cell tropic LAI virus uses the CXCR4 protein as coreceptor for infection. Because the Env ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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