Effects of melatonin on the nitric oxide treated retina
... excessive and uncontrolled intraocular NO elevation led to necrotic and apoptotic cell damage in the retina—retinal swelling, nuclear condensation, and apoptosis; responses very similar to those observed in ONOO2 induced uveitis reported previously.16 NO couples with superoxide anion radical to form ...
... excessive and uncontrolled intraocular NO elevation led to necrotic and apoptotic cell damage in the retina—retinal swelling, nuclear condensation, and apoptosis; responses very similar to those observed in ONOO2 induced uveitis reported previously.16 NO couples with superoxide anion radical to form ...
Profibrillin conversion by proprotein convertases
... enzymes resulted in the proteolytic processing of miniprofibrillin to a fragment that was 15.8 kDa smaller (termed mini-fibrillin) (Fig. 3). This processing was inhibited in the presence of EGTA. Short-fibrillin was not cleaved, indicating that the cleavage of mini-profibrillin occurred in the carbo ...
... enzymes resulted in the proteolytic processing of miniprofibrillin to a fragment that was 15.8 kDa smaller (termed mini-fibrillin) (Fig. 3). This processing was inhibited in the presence of EGTA. Short-fibrillin was not cleaved, indicating that the cleavage of mini-profibrillin occurred in the carbo ...
Serial endosymbiosis or singular event at the origin of eukaryotes?
... ancestor—we may ask: how many homologous base pair sequences in DNA do they share? The number of mutational steps which occurred to produce one from the other is related to the number of generations elapsed since the two populations diverged” (Sagan, 1967 p. 249). On the other hand, her estimates of ...
... ancestor—we may ask: how many homologous base pair sequences in DNA do they share? The number of mutational steps which occurred to produce one from the other is related to the number of generations elapsed since the two populations diverged” (Sagan, 1967 p. 249). On the other hand, her estimates of ...
Identification of plant cytoskeleton-interacting proteins
... Journal compilation ª 2006 Blackwell Publishing Ltd, The Plant Journal, (2006), 48, 367–379 ...
... Journal compilation ª 2006 Blackwell Publishing Ltd, The Plant Journal, (2006), 48, 367–379 ...
A High-Resolution Transcript Profile across the
... initials, analogous to the stem cells proposed for other meristems (Larson, 1994; Laux, 2003). Periclinal (tangential) divisions of these initials then produce phloem or xylem mother cells, which in turn can undergo several rounds of cell division before differentiating (Larson, 1994; Figure 1B). Ca ...
... initials, analogous to the stem cells proposed for other meristems (Larson, 1994; Laux, 2003). Periclinal (tangential) divisions of these initials then produce phloem or xylem mother cells, which in turn can undergo several rounds of cell division before differentiating (Larson, 1994; Figure 1B). Ca ...
Two-dimensional numerical study of flow
... blood vessel) and are subject to a flow at the same time, cell tethers (i.e., long thin membrane cylinders extruded from adhered cells) may form due to the cooperation of hydrodynamic forces and adhesion forces. This phenomenon has been observed in in vitro experiments for different blood components. ...
... blood vessel) and are subject to a flow at the same time, cell tethers (i.e., long thin membrane cylinders extruded from adhered cells) may form due to the cooperation of hydrodynamic forces and adhesion forces. This phenomenon has been observed in in vitro experiments for different blood components. ...
and Virus-Based Biosensing Applications
... results; however, they are generally not sensitive enough to provide reliable and consistent results (van et al. 2001). Viruses and bacteria can also be detected through cell culturing methods. This involves obtaining a sample of interest and filtering it with a membrane capable of removing the micr ...
... results; however, they are generally not sensitive enough to provide reliable and consistent results (van et al. 2001). Viruses and bacteria can also be detected through cell culturing methods. This involves obtaining a sample of interest and filtering it with a membrane capable of removing the micr ...
Characterization of Human Corneal Epithelial Cell Model As a
... could be detected in cHCE as in human cornea. However, multidrug resistance (MDR) 1 and organic anion transporting polypeptide 2B1 was not detected in cHCE; 3) cHCE was demonstrated to possess both esterase and ketone reductase activities known to be present in human cornea; and 4) transport studies ...
... could be detected in cHCE as in human cornea. However, multidrug resistance (MDR) 1 and organic anion transporting polypeptide 2B1 was not detected in cHCE; 3) cHCE was demonstrated to possess both esterase and ketone reductase activities known to be present in human cornea; and 4) transport studies ...
Saccharomyces boulardii Using Intraspecific Protoplast Fusion
... Abstract: Highly efficient bio-therapeutic yeast Saccharomyces boulardii strains, were obtained by intraspecific protoplasts fusion. The selected fusants F1 (S.b.M1 X S.b.M 2) (ad - X lys -) and F2 (S.b.M2 X S.b.M3) (lys -´arg -) and their parents; S.b.M1(ad -), S.b.M2 (lys -) and S.b.M 3 (arg -) as ...
... Abstract: Highly efficient bio-therapeutic yeast Saccharomyces boulardii strains, were obtained by intraspecific protoplasts fusion. The selected fusants F1 (S.b.M1 X S.b.M 2) (ad - X lys -) and F2 (S.b.M2 X S.b.M3) (lys -´arg -) and their parents; S.b.M1(ad -), S.b.M2 (lys -) and S.b.M 3 (arg -) as ...
- University of East Anglia
... Prag and Adams, 2003; Stogios et al., 2005; Xu et al., 2003). Specific interaction partners for Klhl31 have not yet been identified. Interestingly, many Kelch-like family members are implicated in skeletal muscle disease (Gupta and Beggs, 2014). However, not much is known about the role of Klhl31, a ...
... Prag and Adams, 2003; Stogios et al., 2005; Xu et al., 2003). Specific interaction partners for Klhl31 have not yet been identified. Interestingly, many Kelch-like family members are implicated in skeletal muscle disease (Gupta and Beggs, 2014). However, not much is known about the role of Klhl31, a ...
Rab-A2 and Rab-A3 GTPases Define a trans
... For localization studies, we constructed YFP fusions with genomic DNA fragments from all four members of the Rab-A2 subclass (RAB-A2a, -A2b, -A2c, and -A2d) and with the single Rab-A3 protein (RAB-A3). These DNA fragments included the entire intergenic region with additional upstream sequences in so ...
... For localization studies, we constructed YFP fusions with genomic DNA fragments from all four members of the Rab-A2 subclass (RAB-A2a, -A2b, -A2c, and -A2d) and with the single Rab-A3 protein (RAB-A3). These DNA fragments included the entire intergenic region with additional upstream sequences in so ...
Putative Autocleavage of Outer Capsid Protein 1, Allowing Release
... the outer capsid protein 2 is responsible for capping the 5⬘ end of each viral plus-strand RNA as it exits the particle during transcription (34; reviewed in reference 58). The other outer capsid proteins—1, 3, and 1—are involved in cell entry. The majority of the outer capsid lattice is formed ...
... the outer capsid protein 2 is responsible for capping the 5⬘ end of each viral plus-strand RNA as it exits the particle during transcription (34; reviewed in reference 58). The other outer capsid proteins—1, 3, and 1—are involved in cell entry. The majority of the outer capsid lattice is formed ...
Chapter 2.3 Active Cell Processes: Motility, Muscle, and Mechanotransduction
... chemotactic agents. Other cells may have different reasons for migration. Migration is an essential element in growth and development, but also plays a critical role in the metastatic spread of cancer cells. Fibroblasts, normally sedentary factories of extracellular matrix components, become motile ...
... chemotactic agents. Other cells may have different reasons for migration. Migration is an essential element in growth and development, but also plays a critical role in the metastatic spread of cancer cells. Fibroblasts, normally sedentary factories of extracellular matrix components, become motile ...
Early steps in cold sensing by plant cells: the role of actin
... Previous studies (Murata and Los, 1997) have suggested that the plasma membrane acts as the primary sensor of temperature change through dynamic changes in its physical state. Rigidi®cation of plasma membranes by Pd-catalysed hydrogenation leads to the induction of the cold-inducible gene, desA, enc ...
... Previous studies (Murata and Los, 1997) have suggested that the plasma membrane acts as the primary sensor of temperature change through dynamic changes in its physical state. Rigidi®cation of plasma membranes by Pd-catalysed hydrogenation leads to the induction of the cold-inducible gene, desA, enc ...
Liu_umd_0117E_10287 - University of Maryland Libraries
... mononuclear cell (PBMC) and THP-1 cell line. By chromatin immunoprecipitation, I identified three NF-κB binding sites within introns 2 and 4 of the human FcRn gene. These intronic binding sites boost FcRn transcription activities through looping with the promoter region. In contrast, FcRn expression ...
... mononuclear cell (PBMC) and THP-1 cell line. By chromatin immunoprecipitation, I identified three NF-κB binding sites within introns 2 and 4 of the human FcRn gene. These intronic binding sites boost FcRn transcription activities through looping with the promoter region. In contrast, FcRn expression ...
The learners demonstrate an understanding of: The learners shall
... Subject Description: This subject is designed to enhance the understanding of the principles and concepts in the study of biology, particularly life processes at the cellular and molecular levels. It also covers the transformation of energy in organisms. ...
... Subject Description: This subject is designed to enhance the understanding of the principles and concepts in the study of biology, particularly life processes at the cellular and molecular levels. It also covers the transformation of energy in organisms. ...
HISTOLOGICAL AND SEM STUDIES ON ORGANOGENESIS IN
... (Góralski et al., 2005) still displayed callus proliferation and shoot regeneration potential after being maintained more than 2 years. The differences in regeneration efficiency (number of shoots per explant) between our previous studies (Góralski et al., 2005) and the new culture were not statisti ...
... (Góralski et al., 2005) still displayed callus proliferation and shoot regeneration potential after being maintained more than 2 years. The differences in regeneration efficiency (number of shoots per explant) between our previous studies (Góralski et al., 2005) and the new culture were not statisti ...
Minireview: Global Regulation and Dynamics of Ribonucleic Acid
... property of the ribonome forms a “regulators of regulators” feature that can serve to coordinate upstream and downstream functions of gene expression. Indeed, there is massive feedback from translation to transcription and from translation to other posttranscriptional processes providing stability a ...
... property of the ribonome forms a “regulators of regulators” feature that can serve to coordinate upstream and downstream functions of gene expression. Indeed, there is massive feedback from translation to transcription and from translation to other posttranscriptional processes providing stability a ...
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... dFmr1/⫹ larvae exhibit synaptic hyperplasia (see Figures 2A–2E). This enhancement was confirmed by counting the number of synaptic boutons, which rises more than 2-fold in trans-heterozygote individuals (mean 133 boutons, n ⫽ 16) compared to wild-type (mean 61 boutons, n ⫽ 10). This interaction is s ...
... dFmr1/⫹ larvae exhibit synaptic hyperplasia (see Figures 2A–2E). This enhancement was confirmed by counting the number of synaptic boutons, which rises more than 2-fold in trans-heterozygote individuals (mean 133 boutons, n ⫽ 16) compared to wild-type (mean 61 boutons, n ⫽ 10). This interaction is s ...
The Importance of High Resolution Chromosome Analysis in the
... aneuploidies. A further 15 metaphases from the 72-hour cultures were counted the following day, including 5 metaphases that were fully analysed and karyotyped. A total of 20 metaphases were thus screened and 7 metaphases analysed and karyotyped to obtain the final result. As the in situ amniotic flu ...
... aneuploidies. A further 15 metaphases from the 72-hour cultures were counted the following day, including 5 metaphases that were fully analysed and karyotyped. A total of 20 metaphases were thus screened and 7 metaphases analysed and karyotyped to obtain the final result. As the in situ amniotic flu ...
Organelle Fission. Crossing the Evolutionary Divide
... mitochondrial division. Given the near-universal involvement of FtsZ in cell division in prokaryotes, including in the ␣-proteobacterial relatives of mitochondria (Lang et al., 1999; Rothfield et al., 1999), it came as a surprise when release of the complete sequence of the Saccharomyces cerevisiae ...
... mitochondrial division. Given the near-universal involvement of FtsZ in cell division in prokaryotes, including in the ␣-proteobacterial relatives of mitochondria (Lang et al., 1999; Rothfield et al., 1999), it came as a surprise when release of the complete sequence of the Saccharomyces cerevisiae ...
Guidance cues involved in the development of the peripheral
... 3. Development of the enteric nervous system The vast majority of enteric neurons and glial cells arise from neural crest cells that emigrate from the post-otic hindbrain adjacent to somites 1– 7 (Yntema and Hammond, 1954; Le Douarin and Teillet, 1973). Vagal neural crest cells enter the foregut, an ...
... 3. Development of the enteric nervous system The vast majority of enteric neurons and glial cells arise from neural crest cells that emigrate from the post-otic hindbrain adjacent to somites 1– 7 (Yntema and Hammond, 1954; Le Douarin and Teillet, 1973). Vagal neural crest cells enter the foregut, an ...