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Parvalbumin-Expressing Inhibitory Interneurons in Auditory Cortex
Parvalbumin-Expressing Inhibitory Interneurons in Auditory Cortex

... 20 – 80 dB in 15 dB steps, ⱕ10 repetitions). We used this first curve for an initial estimate of CF and sound level threshold. We then obtained a more accurate estimate of CF using a custom tone array (typically 6 frequencies/octave, intensities in 10 dB steps, ⱖ20 repetitions) centered on our initi ...
EFFECT OF ASCORBIC ACID CONCENTRATION ON
EFFECT OF ASCORBIC ACID CONCENTRATION ON

... with ascorbic acid, numbers of dividing cells were observed in roots quiescent center treated with ascorbic acid. On the other words, ascorbic acid stimulates cells of this region and induces cell division. These results are in agreement with those obtained by Liso et al. [1984] and Kerk and Feldman ...
New Insights on Plant Cell Elongation: A Role for Acetylcholine
New Insights on Plant Cell Elongation: A Role for Acetylcholine

... but they may somehow provide a signalling function also in plants. Supporting this role, receptors have been found [24,25]; among them the glutamate receptors are the better characterised (for review [26]). Serotonin and melatonin [21–23], as well as L-glutamate [27], appear to regulate the root sys ...
Control of cell cycle transcription during G1 and S phases
Control of cell cycle transcription during G1 and S phases

... Activation of G1–S transcription Cells commit to enter a new cell cycle during G1 by activating cyclin–CDK-dependent transcription (FIG. 1). G1–S transcriptional activation during late G1 promotes entry into S phase after which expression is turned off. This creates a wave of transcription, which pe ...
RNA polymerase III component Rpc9 regulates
RNA polymerase III component Rpc9 regulates

... expression of p53. Interestingly, WISH result revealed that, compared with the controls, p53 expression was specifically increased in the CHT region of rpc9 −/− mutants (Fig. 6A). Activation of P53 was also confirmed by qRT-PCR and western blot (Fig. S6A, Fig. 6B,C). To determine whether upregulatio ...
Protists - Needham.K12.ma.us
Protists - Needham.K12.ma.us

... cell membrane and too much can cause the cell to burst (passive transport or osmosis). Fortunately for these protozoans, they have a contractile vacuole. A contractile vacuole is a structure that collects and expels excess water from the cell. ...
The hypersensitive response and the induction of cell death in plants
The hypersensitive response and the induction of cell death in plants

... tissues where individual infection events can be followed. One well characterized system is the interaction between the biotrophic fungus Uromyces vignae and cowpea. At 15 h after inoculation during an incompatible interaction, Chen and Heath (1991) observed the following sequence of cytological eve ...
Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO
Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO

Thesis - KI Open Archive
Thesis - KI Open Archive

... Breast cancer (BC) is the most common form of cancer in western women. The grand majority of the afflicted women are eligible for endocrine treatment. Tamoxifen has been the golden standard treatment for more than three decades. Unfortunately, resistance towards this drug is a major concern in the c ...
Ribosome biogenesis and cell growth: mTOR coordinates
Ribosome biogenesis and cell growth: mTOR coordinates

... and ribosome assembly are transcriptionally co-regulated as ‘Ribi regulons’ by the same set of cis- and/or trans-acting factors. Members of the ‘Ribi regulon’ share a polypyrimidine tract, termed 50 TOP (‘terminal oligopyrimidines’ or ‘track of pyrimidines’) sequence at the 50 end of their mRNA. Ana ...
Phosphatidylinositol 4-Phosphate Formation at ER Exit Sites
Phosphatidylinositol 4-Phosphate Formation at ER Exit Sites

... with PtdIns4P (Dowler et al., 2000), inhibited VSV-Gts export at concentrations of 2–3 mM (Figures 1C and 1G and titration in Figure 2D). GST-Fapp1-PH also inhibited the mobilization of COPII vesicle SNARE protein Bet1 (Figure 1D), suggesting that sequestration of PtdIns4P led to general inhibition ...
Traffic into silence: endomembranes and
Traffic into silence: endomembranes and

... are connected either directly or through transport vesicles, the formation of which necessitates the selective recruitment of coat proteins (clathrin, COPI, COPII, and retromer), various GTPases (Sar1, Arf1, and Rabs), and the endosomal sorting complex required for transport (ESCRT) complexes (Kirch ...
Dynamin as a mover and pincher during cell migration and invasion
Dynamin as a mover and pincher during cell migration and invasion

... with lipids, actin and several new binding partners are providing some insight into its lamellipodial localization and support this notion. Dynamin and actin dynamics Several seminal studies provided the initial impetus for pursuing a relationship between dynamin and the actin cytoskeleton. Initiall ...
Lymphatic System Notes (1 of 3)
Lymphatic System Notes (1 of 3)

... Mechanical Barriers  Hair-like structures in membranes ...
bacterial cell shape - Jacobs-Wagner Lab
bacterial cell shape - Jacobs-Wagner Lab

... PEPTIDOGLYCAN HYDROLASES, rapidly followed by insertion of new subunits45, or the attachment of three new glycan strands to the existing structure, which are then automatically pulled into the stress-bearing layer by the cleavage and removal of one old strand46. The large number and variety of hydro ...
Peroxisome degradation requires catalytically active sterol
Peroxisome degradation requires catalytically active sterol

The Kingdom of Fungi is very diverse. Usually it is - Varga
The Kingdom of Fungi is very diverse. Usually it is - Varga

... either sexually or asexually.  During favourable conditions, fungi reproduce ________________. During non-favourable conditions, fungi will lean towards ________________ reproduction.  We will focus on two main groups (phyla) of fungi and their life cycles: Club Fungi and Bread Molds. ...
Human Skin Equivalent Model
Human Skin Equivalent Model

... maintenance of skin function and integrity, is limited. This lack of fundamental knowledge has arisen in part from the less than ideal in vitro and ex vivo models available to facilitate skin research. For example, 2-dimensional (2D) in vitro cell culture studies do not accurately reflect the comple ...
Interesting Facts - Raleigh Charter High School
Interesting Facts - Raleigh Charter High School

... meiosis. Four nuclei are formed, three disintegrate and the other duplicates by mitosis. The daughter nucleus moves across the bridge and fuses with the other daughter nucleus to for a diploid nucleus. Then the cells separate. The old macronucleus disintegrates and a new one is formed from the micro ...
The Lymphoid System - Napa Valley College
The Lymphoid System - Napa Valley College

... Mature T cells leave the circulation to take temporary residence in peripheral tissues. All three types of lymphocytes circulate throughout the body in the ...
IL-5 Receptor-mediated Tyrosine Phosphorylation of SH2
IL-5 Receptor-mediated Tyrosine Phosphorylation of SH2

... with its receptor (I1`5R) which consists of two distinct polypeptide chains, c~and j8 (~/c). Although both I1`5Ro~ and /3c lack a kinase catalytic domain, I1`5 is capable of inducing tyrosine phosphorylation of cellular proteins. We investigated the role of I1`SKcxin tyrosine phosphorylation of mole ...
Sporangiophores' Technique Study Transpiration Pressure Probe
Sporangiophores' Technique Study Transpiration Pressure Probe

... These pressure probe techniques have also been used to study the water relations of the sporangiophores of Phycomyces blakesleeanus (5). In general, pressure probe techniques require that there is a known relationship between the turgor pressure and other parameters which represent the biophysical a ...
An immunologist`s perspective on nutrition, immunity, and infectious
An immunologist`s perspective on nutrition, immunity, and infectious

... pathogens, each containing different PAMP, can interact with a certain combination of PRR on or in a host cell. The variety of PRR complexes triggers specific intracellular signal transduction pathways that will induce specific gene expression profiles, particularly cytokine/chemokine expression, be ...
Temporal and Spatial Distribution of DNA Topoisomerase II Alters
Temporal and Spatial Distribution of DNA Topoisomerase II Alters

... almost the same signal intensity (Fig 1D and E). These results were representative of five similar experiments. Two-dimensional flow cytometric analysis on differentiating HL-60 cells showed alterations in the cell cycle distribution and changes in topo IIa and IIb levels at each cell cycle position ...
A Nanobody-Based System Using Fluorescent Proteins as Scaffolds
A Nanobody-Based System Using Fluorescent Proteins as Scaffolds

... Transgenic lines expressing driver genes such as transcription factors or site-specific recombinases in specific cell populations can then be used to control the expression of genes in responder cassettes. However, the utility of individual lines is limited by a transgene’s functional abilities; rep ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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