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Gene Section BARD1 (BRCA1 associated RING domain 1) in Oncology and Haematology
Gene Section BARD1 (BRCA1 associated RING domain 1) in Oncology and Haematology

... Somatic Several somatic mutation were reported in addition to C557S and Q564H. ...
Changes  in  some factors of the  innate... and  serum  zinc and  iron  concentrations ...
Changes in some factors of the innate... and serum zinc and iron concentrations ...

... some authors (Kushner & Mackiewicz 1986), the levels of native complement proteins decrease in patients with sepsis, but the concentrations of complement activation fragments, such as C3a , C4a and C5a increase (McCabe, Treadwell & DeMaria 1983). ...
Full Text  - Molecular Cancer Research
Full Text - Molecular Cancer Research

... entry from G1 to S and intra-S progression, whereas all 3 CDC25 genes function in G2–M progression (16). The developmental roles of Cdc25 have been partially defined. In mice, Cdc25A is essential for embryonic development. Cdc25A/ embryos are resorbed at around E6.5 due to widespread apoptosis (17) ...
PDF
PDF

... Milliman, 1983). These cDNA clones have been used to investigate the nuclear DNA organization and the pattern of expression of gibb-on sequences. The data, described below, suggest that in wheat the gibb-ons are expressed from small gene families which are all co-regulated in a precise manner. a-Amy ...
Capture of AT-rich Chromatin by ELYS Recruits POM121 and NDC1
Capture of AT-rich Chromatin by ELYS Recruits POM121 and NDC1

... The vertebrate protein ELYS has been shown to play the earliest known role in initiating and targeting nuclear pore assembly to the chromatin (Rasala et al., 2006; Franz et al., 2007). Mutations in MEL-28, the Caenorhabditis elegans homologue of ELYS, show clear defects in nuclear envelope morpholog ...
Ocular Pathology Case Presentation
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... Relapsing polychondritis ...
PDF
PDF

... explants, cells of the putative Gsc domain moved over each other towards the bottle cell side until the explant tipped over (Fig. 4E; supplementary material Movie 3). As migration continued (Fig. 4E), deeper cells became exposed as cells above them moved apart (supplementary material Movie 3). In th ...
GFP is the way to glow: bioimaging of the plant endomembrane
GFP is the way to glow: bioimaging of the plant endomembrane

... with a molecular mass of approximately 27 kDa. It emits green fluorescence upon excitation with UV or blue light. As specific secretory proteins or signals can be fused to GFP, usually without altering their targeting, it is a useful alternative to conventional dyes previously used to investigate en ...
Downstream Regulatory Element Antagonist Modulator Regulates
Downstream Regulatory Element Antagonist Modulator Regulates

... Cell culture, transfection, and reporter assays. Human carcinoma human embryonic kidney 293 (HEK293) and human neuroblastoma SHSY5Y cells were cultured in DMEM supplemented with 10% heatinactivated fetal calf serum. For the luciferase reporter assays, 1 ⫻ 10 6 cells were plated on 60 mm dishes. Six ...
Fluorescent peptides as molecular probes
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... have been used in visualising cellular processes. AnaSpec was able to track the uptake of dye-labeled CPP using fluorescence microscopy. CPPs (cell penetrating peptides), also known as protein transduction domains (PTDs), are carriers with small peptide domains that can freely cross cell membranes. ...
Tet System Approved FBS
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... Tet-On® Systems and suppressing maximum expression levels in Tet-Off® systems. The solution: Tet System Approved FBS from Clontech, the only functionallytested FBS approved for use with our TetOn and Tet-Off Systems. The functional testing makes our FBS superior because it ensures that you will be a ...
FtsK-Dependent Dimer Resolution on Multiple Chromosomes
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... distribution of these motifs on chromosome I and chromosome II supporting the idea that FtsK translocation serves to bring together the resolution sites carried by a dimer at the time of cell division. Taken together, these results suggest that the same FtsK-dependent mechanism coordinates dimer res ...
DESCRIPTION FUNCTIONS INDICATIONS SUGGESTED USE
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... caused by toxic free radicals and reactive oxygen species (e.g., peroxides) which are produced during normal oxygen metabolism, by other chemical reactions, and by toxic agents in the environment. Free radicals, once formed, are capable of disrupting metabolic activity and cell structure. When this ...
Cell Fate Specification in the C. elegans Embryo
Cell Fate Specification in the C. elegans Embryo

... reporters has been developed (discussed below) (Murray et al., 2006). In both cases, lineage reconstruction can be facilitated by computer software such as Simi BioCell or StarryNite (Schnabel et al., 1997; Bao et al., 2006; Murray et al., 2006). Studying cell fate at this level can is important for ...
Calcium-Dependent Prevention of Neuronal Apoptosis by Lithium Ion
Calcium-Dependent Prevention of Neuronal Apoptosis by Lithium Ion

... death with supplement of appropriate Ca2⫹ as well as neurotrophic factors (Franklin and Johnson, 1994), we examined whether Ca2⫹ would mediate the antiapoptosis action of Li⫹. Cortical neurons treated with Li⫹ revealed an immediate increase in [Ca2⫹]i. This increase was maximally observed within 2 m ...
pdf: Baskin 2013
pdf: Baskin 2013

... wires.wiley.com/devbio ...
1. Describe the steps of the scientific method. 2. Define the terms
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... What are the common characteristics of all living things? Describe the levels of organization of life beginning with the smallest living unit and progressing up in complexity to ecosystems. Compare and contrast DNA and RNA. Describe the 3 types of molecular bonds. Which is strongest and which is wea ...
Endocytosis Via Caveolae
Endocytosis Via Caveolae

... 50, 57–67). The entry process of this non-enveloped DNA virus, analyzed in several laboratories including ours, is emerging as a useful paradigm in the field. SV40 has several advantages as a model ligand. The particle itself is well characterized in terms of composition and structure. The X-ray str ...
FasL gene knock-down therapy enhances the
FasL gene knock-down therapy enhances the

... very difficult to treat. The aggressive behavior of these neoplasms and their limited responsiveness to therapy has been attributed in part to the ability of these tumors to evade the immune system. Gliomas, like many other solid tumors, express components of numerous immune escape mechanisms, inclu ...
(Solanum tuberosum L.) plantlets to gradient saline stress
(Solanum tuberosum L.) plantlets to gradient saline stress

... at 150 mM NaCl (Hmida-Sayari et al., 2005). Bruns and HechtBuchholz (1990) found that the salt-induced changes were mainly observed in the chloroplasts, especially in the thylakoids. Different potato cultivars reacted differently to salt stress. Mitsuya et al. (2000) found the degradation of thylako ...
Tropomyosin 1: Multiple roles in the developing heart and in the
Tropomyosin 1: Multiple roles in the developing heart and in the

... Keywords: Cardiac development Congenital heart defects Structural protein Tropomyosin 1 ...
Taxonomy, biology and physiology of fungi
Taxonomy, biology and physiology of fungi

... H. Complex cytoplasm with internal organelles, microfilaments and microtubules ...
Degree Type – Bachelor of Science (BS) Degree Title – Biology
Degree Type – Bachelor of Science (BS) Degree Title – Biology

... 1. Role  of  the  Cell:  The  Biology  graduate  knows  the  role  of  the  cell  in  life  and  living  systems,  and  understands  the   interrelationships  among  subcellular  structures  that  contribute  to  its  functioning  as  a ...
The more and smaller cells mutants of Arabidopsis
The more and smaller cells mutants of Arabidopsis

... throughout the leaf primordium and is gradually restricted to the proximal part (Donnelly et al., 1999). Arrest of cell cycle and subsequent post-mitotic cell expansion occur from the distal to the proximal part of a young leaf. The regulatory mechanisms of cell proliferation and cell expansion have ...
MEK kinase activity is not necessary for Raf
MEK kinase activity is not necessary for Raf

... antibody to platelet endothelial cell adhesion molecule-1 (PECAM-1; Figure 1E). PECAM-1 staining of the raf-1±/± embryos also revealed abnormal vascular network formation (Figure 1F±I). In the head region, there was a reduction in the number of large and small blood vessels, the vessels were disorga ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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