Therapeutic approaches to Lysosomal Storage Disorders
... required for membrane fusion. SNARE proteins are classified as vesicle SNAREs (vSNAREs), located on the vesicles membrane, and target SNAREs (t-SNAREs), located on the membranes of target compartments. SNAREs may vary in size and composition, but they all share a 60-70 amino acid cytosolic domain ( ...
... required for membrane fusion. SNARE proteins are classified as vesicle SNAREs (vSNAREs), located on the vesicles membrane, and target SNAREs (t-SNAREs), located on the membranes of target compartments. SNAREs may vary in size and composition, but they all share a 60-70 amino acid cytosolic domain ( ...
the sting bulb gland in myrmecia and nothomyrmecia
... them (Fig. 6). The gland also occurs in the sting of the queen of Myrmeciapilosula that I had available for examination, although the incomplete section series did not allow me to estimate its development relative to the situation in workers. The secretory cells have a rounded to polygonal appearanc ...
... them (Fig. 6). The gland also occurs in the sting of the queen of Myrmeciapilosula that I had available for examination, although the incomplete section series did not allow me to estimate its development relative to the situation in workers. The secretory cells have a rounded to polygonal appearanc ...
BIOLOGY I - one credit - COMPETENCIES AND OBJECTIVES
... a. Draw conclusions about how organisms are classified into a hierarchy of groups and subgroups based on similarities that reflect their evolutionary relationships. (DOK 2) Characteristics of the six kingdoms Major levels in the hierarchy of taxa (e.g., kingdom, phylum/division, class, order, fa ...
... a. Draw conclusions about how organisms are classified into a hierarchy of groups and subgroups based on similarities that reflect their evolutionary relationships. (DOK 2) Characteristics of the six kingdoms Major levels in the hierarchy of taxa (e.g., kingdom, phylum/division, class, order, fa ...
GLYCOLIPID ANCHORING OF CELL SURFACE PROTEINS Mark C
... property was lost on PI-PLC treatment suggesting that the lipophilic properties of AP were intimately associated with AP itself, rather than being some property of the lipid bilayer with which it was associated, and could be explained by the covalent linkage of a PI molecule to the protein. Similar ...
... property was lost on PI-PLC treatment suggesting that the lipophilic properties of AP were intimately associated with AP itself, rather than being some property of the lipid bilayer with which it was associated, and could be explained by the covalent linkage of a PI molecule to the protein. Similar ...
An Isotype-specific Activator of Major Histocompatibility Complex
... genes critical for class II expression (7–11). Two of these genes, CIITA (class II transactivator) and RFX5, have been isolated by expression cloning from a wild-type cDNA library using cell lines from MHC class II CID complementation groups II and IV, respectively, as recipients. It should be noted ...
... genes critical for class II expression (7–11). Two of these genes, CIITA (class II transactivator) and RFX5, have been isolated by expression cloning from a wild-type cDNA library using cell lines from MHC class II CID complementation groups II and IV, respectively, as recipients. It should be noted ...
Suffix Meaning -ac pertaining to
... -fication -fida -form -fusion -gen -genesis -genic -globin -globulin -grade -gram -graph -graphy -gravida -hexia -ia -iac ...
... -fication -fida -form -fusion -gen -genesis -genic -globin -globulin -grade -gram -graph -graphy -gravida -hexia -ia -iac ...
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... among the immature stages was not significantly different. The highest expression of the septin gene fragment was detected in the 2-day old female, and this was not significantly different from the 2-day old male (p > 0.05, Fig. 3). Detection of the septin fragment in the developmental stages of Ae ...
... among the immature stages was not significantly different. The highest expression of the septin gene fragment was detected in the 2-day old female, and this was not significantly different from the 2-day old male (p > 0.05, Fig. 3). Detection of the septin fragment in the developmental stages of Ae ...
"Monoclonal Antibodies to Human Cell Surface Antigens". In
... During the last 25 years, large numbers of monoclonal antibodies (MAbs) have been produced that have facilitated the purification and functional characterization of a plethora of leukocyte surface molecules. The antibodies have been even more useful as markers for cell populations, allowing the coun ...
... During the last 25 years, large numbers of monoclonal antibodies (MAbs) have been produced that have facilitated the purification and functional characterization of a plethora of leukocyte surface molecules. The antibodies have been even more useful as markers for cell populations, allowing the coun ...
Extended PDF
... pellicles at the air-liquid interface of standing cultures (Aguilar et al., 2007; Branda et al., 2001a; Lopez et al., 2009; Vlamakis et al., 2008). Cells in the pellicles are held together by an extracellular matrix consisting of exopolysaccharide and amyloidlike fibers largely composed of the prote ...
... pellicles at the air-liquid interface of standing cultures (Aguilar et al., 2007; Branda et al., 2001a; Lopez et al., 2009; Vlamakis et al., 2008). Cells in the pellicles are held together by an extracellular matrix consisting of exopolysaccharide and amyloidlike fibers largely composed of the prote ...
Grape berry vacuole: a complex and heterogeneous membrane
... observable in some cells (Figure 2). The diversity of vacuolar functions parallels their diversity in ...
... observable in some cells (Figure 2). The diversity of vacuolar functions parallels their diversity in ...
Interaction of rat alveolar macrophages with dental composite dust
... Background: Dental composites have become the standard filling material to restore teeth, but during the placement of these restorations, high amounts of respirable composite dust (<5 μm) including many nano-sized particles may be released in the breathing zone of the patient and dental operator. He ...
... Background: Dental composites have become the standard filling material to restore teeth, but during the placement of these restorations, high amounts of respirable composite dust (<5 μm) including many nano-sized particles may be released in the breathing zone of the patient and dental operator. He ...
hematopoietic stem cells: to be or notch to be
... The hematopoietic system has served for decades as a pioneer model for studying and deciphering the behavior of somatic Stem Cells and the mechanisms that regulate cell differentiation, and in fact, the knowledge generated on hematopoietic stem cell biology has guided the understanding of other type ...
... The hematopoietic system has served for decades as a pioneer model for studying and deciphering the behavior of somatic Stem Cells and the mechanisms that regulate cell differentiation, and in fact, the knowledge generated on hematopoietic stem cell biology has guided the understanding of other type ...
The Bacterial Nucleoid
... 1970, for references). Phase contrast microscopy as well as A uorescence microscopy have also been used to visualize the nucleoid. Some results obtained by Mason & Powelson (1956), employing a high concentration of gelatin in the medium to increase the phase contrast within the bacteria, are shown i ...
... 1970, for references). Phase contrast microscopy as well as A uorescence microscopy have also been used to visualize the nucleoid. Some results obtained by Mason & Powelson (1956), employing a high concentration of gelatin in the medium to increase the phase contrast within the bacteria, are shown i ...
Debeer S et al, 2013
... LC in both porcine and human epidermis had a rounded cell body with delicate dendritic processes, and were mostly present in the lowermost epidermal layers. In porcine skin, they were regularly distributed at a density evaluated at 600-800 cells/mm2 on epidermal sheets (data not shown). Occasional C ...
... LC in both porcine and human epidermis had a rounded cell body with delicate dendritic processes, and were mostly present in the lowermost epidermal layers. In porcine skin, they were regularly distributed at a density evaluated at 600-800 cells/mm2 on epidermal sheets (data not shown). Occasional C ...
cell-substratum adhesion of neurite growth cones, and its role in
... and are small. On polylysine-treated glass growth cones are highly spread, microspikes reach treat lengths and extensive adhesive contacts underlie growth cones, microspikes and nerve fibers. Veils, expanded from the growth cone, are adherent to the substratum either centrally or laterally, while th ...
... and are small. On polylysine-treated glass growth cones are highly spread, microspikes reach treat lengths and extensive adhesive contacts underlie growth cones, microspikes and nerve fibers. Veils, expanded from the growth cone, are adherent to the substratum either centrally or laterally, while th ...
www.xtremepapers.net
... widespread candidature. The question papers are closely related and the relationships between them have been thoroughly established using our assessment expertise. All versions of the paper give assessment of equal standard. The content assessed by the examination papers and the type of questions is ...
... widespread candidature. The question papers are closely related and the relationships between them have been thoroughly established using our assessment expertise. All versions of the paper give assessment of equal standard. The content assessed by the examination papers and the type of questions is ...
Boron Functions in Plants: Looking Beyond the
... Lactifers (latex-forming species) have by far the highest B requirement followed by leguminous plants, then the remaining dicots and the lily family of monocots, and finally the lowest B requirements are found in graminacous plants (Mengel and Kirkby, 2001). Importantly, when graminacous plants flow ...
... Lactifers (latex-forming species) have by far the highest B requirement followed by leguminous plants, then the remaining dicots and the lily family of monocots, and finally the lowest B requirements are found in graminacous plants (Mengel and Kirkby, 2001). Importantly, when graminacous plants flow ...
Topological schemas of cognitive maps and spatial learning in the
... neuronal basis of Tolman’s cognitive map, thus providing this abstract concept with a concrete neurophysiological basis. In the ensuing decades, it was realized that there are many brain regions involved in cognitive mapping of the environment [4], yet there is still no consensus on either the physi ...
... neuronal basis of Tolman’s cognitive map, thus providing this abstract concept with a concrete neurophysiological basis. In the ensuing decades, it was realized that there are many brain regions involved in cognitive mapping of the environment [4], yet there is still no consensus on either the physi ...
Patterns of Nogo mRNA and Protein Expression in the Developing
... expression analysis is therefore limited. For immunohistochemistry the antibodies were diluted in PBS, pH 7.4, containing 1% normal goat serum as follows: mAb I N-1 hybridoma supernatant, 1:5; AS Bruna, 1:7500; AS Bianca, 1:2000; AS 472, 1:2000; AS 818, 1:2000; affinitypurified AS 818, 1:50; anti-my ...
... expression analysis is therefore limited. For immunohistochemistry the antibodies were diluted in PBS, pH 7.4, containing 1% normal goat serum as follows: mAb I N-1 hybridoma supernatant, 1:5; AS Bruna, 1:7500; AS Bianca, 1:2000; AS 472, 1:2000; AS 818, 1:2000; affinitypurified AS 818, 1:50; anti-my ...
Microbial environments confound antibiotic efficacy
... antibiotics. They may also form the basis for novel—and more effective—antibacterial compounds. This cell-death pathway also provides insight into how bacteria may evade antibiotics through changes in metabolism. We now have a context for understanding how genetic mutations that seem unrelated to an ...
... antibiotics. They may also form the basis for novel—and more effective—antibacterial compounds. This cell-death pathway also provides insight into how bacteria may evade antibiotics through changes in metabolism. We now have a context for understanding how genetic mutations that seem unrelated to an ...
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... parent antibiotics, because some of those formamidinoantracyclines exhibited lowered cardiotoxicity in vivo (Wąsowska et al., 2005) and ability to induce differentiation of tumor cells (Jakubowska et al., 2007; Szuławska et al., 2007) and were found to be highly cytotoxic to several neoplastic cell ...
... parent antibiotics, because some of those formamidinoantracyclines exhibited lowered cardiotoxicity in vivo (Wąsowska et al., 2005) and ability to induce differentiation of tumor cells (Jakubowska et al., 2007; Szuławska et al., 2007) and were found to be highly cytotoxic to several neoplastic cell ...
Identification and characterisation of SMIM1
... defence could become the enemy as, in its eagerness to defend, it will end up destroying not only the intruders, but also itself in the process. Blood is life-giving. It is complex and it is crucial. And it can become treacherous and fragile. It makes us unique and sets us apart. As such, extensive ...
... defence could become the enemy as, in its eagerness to defend, it will end up destroying not only the intruders, but also itself in the process. Blood is life-giving. It is complex and it is crucial. And it can become treacherous and fragile. It makes us unique and sets us apart. As such, extensive ...
a biological “arms race” - Open Access Journals at BC
... as a result of many interactions with diverse viruses, host restriction factors bear signatures of positive selection. Another defining factor of restriction factors is their relationships with viral antagonist proteins. In many cases, viruses have evolved specific proteins to evade the mechanism of ...
... as a result of many interactions with diverse viruses, host restriction factors bear signatures of positive selection. Another defining factor of restriction factors is their relationships with viral antagonist proteins. In many cases, viruses have evolved specific proteins to evade the mechanism of ...
PHYSIOLOGICAL AND CHEMICAL CHARACTERISTICS OF
... was done elsewhere else (11). This is because the relatively large molecule of the antibacterial polypeptide unlike the relatively small molecules of antibiotics, can not diffuse in agar and create a zone of dead cells. Under these circumstances, the ABA was estimated by the clarity of the PJ spots ...
... was done elsewhere else (11). This is because the relatively large molecule of the antibacterial polypeptide unlike the relatively small molecules of antibiotics, can not diffuse in agar and create a zone of dead cells. Under these circumstances, the ABA was estimated by the clarity of the PJ spots ...