
Course Objectives
... Students must attend 80% of the meetings for each course in order to receive credit for a course. If a student wants to withdraw from the course, he/she must do so through Hinds Community College as well as Florence High School. Withdrawal must be from the lab in addition to the lecture. Failure to ...
... Students must attend 80% of the meetings for each course in order to receive credit for a course. If a student wants to withdraw from the course, he/she must do so through Hinds Community College as well as Florence High School. Withdrawal must be from the lab in addition to the lecture. Failure to ...
Homeotic genes controlling flower development in Antirrhinum
... these similarities reflect the action of homologous genes in the two species. The action of many gene functions in overlapping regions could give each whorl a unique combination of functions. For example, if genes acting in regions A, B and C are required for three functions a, b, and c respectively ...
... these similarities reflect the action of homologous genes in the two species. The action of many gene functions in overlapping regions could give each whorl a unique combination of functions. For example, if genes acting in regions A, B and C are required for three functions a, b, and c respectively ...
Reduced expression of the SHORT-ROOT gene increases the rates
... role in root meristem formation and maintenance and in the cambial region of hypocotyl cuttings [8]. In Populus trichocarpa, PtSHR1 is a close homolog of the Arabidopsis RAM regulator, AtSHR, and its expression has been detected in the VC of rapidly growing stems of hybrid poplar [9]. Another relate ...
... role in root meristem formation and maintenance and in the cambial region of hypocotyl cuttings [8]. In Populus trichocarpa, PtSHR1 is a close homolog of the Arabidopsis RAM regulator, AtSHR, and its expression has been detected in the VC of rapidly growing stems of hybrid poplar [9]. Another relate ...
The Effects of Zygotic Lethal Mutations on Female Germ
... effects of EMS-induced zygotic lethal mutations at 48 loci were examined using the dominant female-sterile technique. Three categories of effects were found. In the first group (13 out of 48), no maternal effect was detected. The second set (20 out of 48) exhibited maternal effects on oogenesis, emb ...
... effects of EMS-induced zygotic lethal mutations at 48 loci were examined using the dominant female-sterile technique. Three categories of effects were found. In the first group (13 out of 48), no maternal effect was detected. The second set (20 out of 48) exhibited maternal effects on oogenesis, emb ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... been identified, although for most of these variants the biological mechanisms remain to be elucidated 1. Interestingly, the majority of disease-associated genetic variation is located in regulatory regions of the genome 2, including transcription-factor-occupied regions and DNase I hypersensitive s ...
... been identified, although for most of these variants the biological mechanisms remain to be elucidated 1. Interestingly, the majority of disease-associated genetic variation is located in regulatory regions of the genome 2, including transcription-factor-occupied regions and DNase I hypersensitive s ...
The role of the ovarian tumor locus in Drosophila
... the possible sexual transformation of 2X:2A ; otu− (chromosomally female) germ cells using molecular markers. Gönczy et al. (1992) have described two P[w+ lacZ] enhancer traps (line 590 and line 606) that expressed the βgalactosidase reporter gene in the male germ line in both stem cells and mitotic ...
... the possible sexual transformation of 2X:2A ; otu− (chromosomally female) germ cells using molecular markers. Gönczy et al. (1992) have described two P[w+ lacZ] enhancer traps (line 590 and line 606) that expressed the βgalactosidase reporter gene in the male germ line in both stem cells and mitotic ...
On the genetics of hypodontia and microdontia
... and the father, it is likely that they constitute two phenotypic variants of hypodontia. The probands have a condition considerably more severe than the mere sum of their parents' anomalies. The most straightforward explanation for this is that the parents are heterozygous and both affected daughter ...
... and the father, it is likely that they constitute two phenotypic variants of hypodontia. The probands have a condition considerably more severe than the mere sum of their parents' anomalies. The most straightforward explanation for this is that the parents are heterozygous and both affected daughter ...
Evolution of meiosis genes in sexual vs. asexual Potamopyrgus
... otherwise similar sexual and asexual taxa. I address these questions by studying the evolution of genes critical to sexual reproduction in sexual and asexual lineages of Potamopyrgus antipodarum, a New Zealand freshwater snail. Because genes used only for sexual reproduction should have little or no ...
... otherwise similar sexual and asexual taxa. I address these questions by studying the evolution of genes critical to sexual reproduction in sexual and asexual lineages of Potamopyrgus antipodarum, a New Zealand freshwater snail. Because genes used only for sexual reproduction should have little or no ...
American Scientist
... Figure 1. Sports such as bicycle racing illustrate some of the same conflicts between group and individual interests seen in biological evolution. A small group of cyclists can sustain a higher speed if they coordinate their efforts, with each rider taking a turn at the front of the group, where win ...
... Figure 1. Sports such as bicycle racing illustrate some of the same conflicts between group and individual interests seen in biological evolution. A small group of cyclists can sustain a higher speed if they coordinate their efforts, with each rider taking a turn at the front of the group, where win ...
Genes and Genetic Testing in Hereditary Ataxias
... other symptoms like intellectual disability, with known genetic association. Early work on the genetic origins of ataxia began in 1993 with the discovery of a CAG repeat responsible for spinocerebellar ataxia (SCA) type 1 [5]. Continued screening for CAG repeat expansions identified several addition ...
... other symptoms like intellectual disability, with known genetic association. Early work on the genetic origins of ataxia began in 1993 with the discovery of a CAG repeat responsible for spinocerebellar ataxia (SCA) type 1 [5]. Continued screening for CAG repeat expansions identified several addition ...
Protein export elements from Lactococcus lactis
... and Clostridium thermocellumcellulase A, using the native signal peptides of these proteins (Scheilink et al. 1989). The secretion by Lactococcus lactis of Bacillus subtilis neutral protease fused to a lactococcal promoter was demonstrated by van de Guchte et al. (1990). Escherichia coli TEM-13-lact ...
... and Clostridium thermocellumcellulase A, using the native signal peptides of these proteins (Scheilink et al. 1989). The secretion by Lactococcus lactis of Bacillus subtilis neutral protease fused to a lactococcal promoter was demonstrated by van de Guchte et al. (1990). Escherichia coli TEM-13-lact ...
Spectrum of Mutations in MMAB Identified by
... I would like to express my appreciation to my mentor, David Rosenblatt, for providing me the opportunity, not only once but twice, to be actively engaged in a field of personal interest. Being a member of the Rosenblatt team provides the friendship, support and unquestioning assistance of a very spe ...
... I would like to express my appreciation to my mentor, David Rosenblatt, for providing me the opportunity, not only once but twice, to be actively engaged in a field of personal interest. Being a member of the Rosenblatt team provides the friendship, support and unquestioning assistance of a very spe ...
Recombination in large RNA viruses: Coronaviruses
... under a variety of natural and experimental conditions. The capacity to recombine has now been demonstrated in several different coronaviruses. Recombination is an important mechanism contribut- ...
... under a variety of natural and experimental conditions. The capacity to recombine has now been demonstrated in several different coronaviruses. Recombination is an important mechanism contribut- ...
Recombination and epistasis facilitate introgressive hybridization
... where p(i, c, g) is the probability that the number of exotic alleles located in the upper region from the crossing-over point c in the ordered gene map of the chromosome is i, provided that the gamete class is g, and d(z) is a function with a value of 1 when z = 0, or otherwise 0. The two summation ...
... where p(i, c, g) is the probability that the number of exotic alleles located in the upper region from the crossing-over point c in the ordered gene map of the chromosome is i, provided that the gamete class is g, and d(z) is a function with a value of 1 when z = 0, or otherwise 0. The two summation ...
Convergent Evolution in the Genetic Basis of Müllerian Mimicry in
... least 4 of the 21 chromosomes are involved in wing color patterning (Sheppard et al. 1985; Joron et al. 2006). H. erato has a similar architecture, with the involvement of at least 4 different chromosomes. Recent work has shown preliminary evidence for further homology between the two species in add ...
... least 4 of the 21 chromosomes are involved in wing color patterning (Sheppard et al. 1985; Joron et al. 2006). H. erato has a similar architecture, with the involvement of at least 4 different chromosomes. Recent work has shown preliminary evidence for further homology between the two species in add ...
The Evolution of Vertebrate Sex Chromosomes
... produced the first genetic map, consisting of six sex-linked genes (Sturtevant 1913). The ...
... produced the first genetic map, consisting of six sex-linked genes (Sturtevant 1913). The ...
lac
... lacY lacA Its own promoter and encodes a repressor DNA protein. Transcription It is not part of the operon mRNA ...
... lacY lacA Its own promoter and encodes a repressor DNA protein. Transcription It is not part of the operon mRNA ...
Convergent Evolution in the Genetic Basis of Müllerian
... least 4 of the 21 chromosomes are involved in wing color patterning (Sheppard et al. 1985; Joron et al. 2006). H. erato has a similar architecture, with the involvement of at least 4 different chromosomes. Recent work has shown preliminary evidence for further homology between the two species in add ...
... least 4 of the 21 chromosomes are involved in wing color patterning (Sheppard et al. 1985; Joron et al. 2006). H. erato has a similar architecture, with the involvement of at least 4 different chromosomes. Recent work has shown preliminary evidence for further homology between the two species in add ...
Rosana Segovia HGT - Repositorio Digital USFQ
... that are capable of capturing additional gene cassettes. These gene cassettes are promoterless mobile elements made up of a gene-coding region that usually encodes for antibiotic resistance genes, such as ß-lactamase and acetyl transferases. Gene cassettes may also encode for genes that protect bact ...
... that are capable of capturing additional gene cassettes. These gene cassettes are promoterless mobile elements made up of a gene-coding region that usually encodes for antibiotic resistance genes, such as ß-lactamase and acetyl transferases. Gene cassettes may also encode for genes that protect bact ...
Stochasticity in the Genotype-Phenotype Map
... (2015) considers when bet-hedging can offer a greater fitness advantage than phenotypic plasticity, where phenotypes are modulated via the environmental variation (Via and Lande 1985). This previous work derives constraints on the cost of sensing, predictability of environmental fluctuations, and the ...
... (2015) considers when bet-hedging can offer a greater fitness advantage than phenotypic plasticity, where phenotypes are modulated via the environmental variation (Via and Lande 1985). This previous work derives constraints on the cost of sensing, predictability of environmental fluctuations, and the ...
The Plastidic Phosphoglucomutase from
... “starchless” phenotype in Arabidopsis and N. sylvestris. The P. sativum PGM mutant, rug3, has a wrinkled seed phenotype with only 1% of the seed dry weight as starch, compared with 60% in the wild type (Harrison et al., 1998). The reduction on starch synthesis in rug3 is also accompanied by a signif ...
... “starchless” phenotype in Arabidopsis and N. sylvestris. The P. sativum PGM mutant, rug3, has a wrinkled seed phenotype with only 1% of the seed dry weight as starch, compared with 60% in the wild type (Harrison et al., 1998). The reduction on starch synthesis in rug3 is also accompanied by a signif ...
Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD S-L. Cheng
... disease (COPD). Nevertheless, only 10–20% of chronic smokers develop the severe impairment of pulmonary function associated with COPD [1, 2]. This indicates the possible contribution of environmental or genetic cofactors to the development of COPD. Although cofactors, such as childhood viral infecti ...
... disease (COPD). Nevertheless, only 10–20% of chronic smokers develop the severe impairment of pulmonary function associated with COPD [1, 2]. This indicates the possible contribution of environmental or genetic cofactors to the development of COPD. Although cofactors, such as childhood viral infecti ...
Chapter 13 - ScienceToGo
... chromosome sets from diploid to haploid • Like mitosis, meiosis is preceded by the replication of chromosomes • Meiosis takes place in two sets of cell divisions, called meiosis I and meiosis II • The two cell divisions result in four daughter cells, rather than the two daughter cells in ...
... chromosome sets from diploid to haploid • Like mitosis, meiosis is preceded by the replication of chromosomes • Meiosis takes place in two sets of cell divisions, called meiosis I and meiosis II • The two cell divisions result in four daughter cells, rather than the two daughter cells in ...
Molecular Imaging - Engineering Computing Facility
... processes at the cellular and molecular level [1]. Therefore, it allows processes such as gene expression and protein-protein interactions to be imaged. It results from the convergence of the disciplines of medical imaging and cellular biology. Research in cellular biology using a systems biology ap ...
... processes at the cellular and molecular level [1]. Therefore, it allows processes such as gene expression and protein-protein interactions to be imaged. It results from the convergence of the disciplines of medical imaging and cellular biology. Research in cellular biology using a systems biology ap ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse