
(1977) New Genes for Resistance to the Brown Planthopper in Rice
... families, 42 had an excess of susceptible seedlings approximating 1 resistant:3 susceptible in each family. Thus, one of the two genes conveying resistance in Ptb 21 is recessive. Tile remaining 90 segregating F~ families had an excess of resistant seedlings approximating 3 resistant:l susceptible i ...
... families, 42 had an excess of susceptible seedlings approximating 1 resistant:3 susceptible in each family. Thus, one of the two genes conveying resistance in Ptb 21 is recessive. Tile remaining 90 segregating F~ families had an excess of resistant seedlings approximating 3 resistant:l susceptible i ...
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence
... research, QTL mapping and correlation analysis of three related traits (PD trait(PDH), ratio of thickness to width (RTW) and days of full maturity (DFM) ) were performeded in 112 strains of soybean recombinant inbred lines (RIL) population (JINF population) by using methods of composite interval map ...
... research, QTL mapping and correlation analysis of three related traits (PD trait(PDH), ratio of thickness to width (RTW) and days of full maturity (DFM) ) were performeded in 112 strains of soybean recombinant inbred lines (RIL) population (JINF population) by using methods of composite interval map ...
Transvection Is Common Throughout the Drosophila
... cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the characteristic morphologies of its constituent neurons (Truman et ...
... cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the characteristic morphologies of its constituent neurons (Truman et ...
Genome-wide analysis by SNP Array
... Case 3: Detection of genomic changes in patient with premature ovarian failure presenting a normal Karyotype Patients with premature ovarian failure (POF) show partial deletions on chromosome X and Xautosome translocations. Seventy per cent of the deletions in the terminal end of chromosome X are re ...
... Case 3: Detection of genomic changes in patient with premature ovarian failure presenting a normal Karyotype Patients with premature ovarian failure (POF) show partial deletions on chromosome X and Xautosome translocations. Seventy per cent of the deletions in the terminal end of chromosome X are re ...
Case Report Novel Sonic Hedgehog Mutation in a Couple
... for TGA), which suggests that mutations in this adjacent residues are associated with an important phenotypic clinical variability. The etiology of the wide phenotypic spectrum is not yet understood, and it has been proposed that other genes or environmental influences may contribute as gene modifie ...
... for TGA), which suggests that mutations in this adjacent residues are associated with an important phenotypic clinical variability. The etiology of the wide phenotypic spectrum is not yet understood, and it has been proposed that other genes or environmental influences may contribute as gene modifie ...
two loci affecting b cell responses to b cell
... Cytokines are molecules affecting cell growth and differentiation and are considered to be important intercellular regulatory signals (1). Within the imm u n e system, lymphokines are leukocyte-derived cytokines with effects on B and T cell differentiation and proliferation (2, 3). A m o n g these a ...
... Cytokines are molecules affecting cell growth and differentiation and are considered to be important intercellular regulatory signals (1). Within the imm u n e system, lymphokines are leukocyte-derived cytokines with effects on B and T cell differentiation and proliferation (2, 3). A m o n g these a ...
Supplementary Infomation (doc 1650K)
... NESDA = 0.99, and ORKNEY = 1.03. For the overall meta-analysis, the inflation factor (λ) was 0.997. If λ is large (for example, > 1.2), there is evidence that the observed test statistics deviate from the expected. This could be due to true associations but is more likely due to a systematic bias (f ...
... NESDA = 0.99, and ORKNEY = 1.03. For the overall meta-analysis, the inflation factor (λ) was 0.997. If λ is large (for example, > 1.2), there is evidence that the observed test statistics deviate from the expected. This could be due to true associations but is more likely due to a systematic bias (f ...
Student Accomplishments for 2005 – 2006
... Genetic health status of the corn snake, Elaphe gutatta, an endangered species in New Jersey Tim Jarvela (Senior) Mentor: Dr. Amanda Norvell Development of a genetic screen in Drosophila melanogaster for identifying new genes that are required for the production of correctly formed eggs Jordan Kapla ...
... Genetic health status of the corn snake, Elaphe gutatta, an endangered species in New Jersey Tim Jarvela (Senior) Mentor: Dr. Amanda Norvell Development of a genetic screen in Drosophila melanogaster for identifying new genes that are required for the production of correctly formed eggs Jordan Kapla ...
Molecular Characterization of a Chromosomal Rearrangement Involved in the Adaptive Evolution
... have found, however, that the SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5⬘ upstream regions of the SSU1 and E ...
... have found, however, that the SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5⬘ upstream regions of the SSU1 and E ...
Chapter 13
... chromosome sets from diploid to haploid • Like mitosis, meiosis is preceded by the replication of chromosomes • Meiosis takes place in two sets of cell divisions, called meiosis I and meiosis II • The two cell divisions result in four daughter cells, rather than the two daughter cells in ...
... chromosome sets from diploid to haploid • Like mitosis, meiosis is preceded by the replication of chromosomes • Meiosis takes place in two sets of cell divisions, called meiosis I and meiosis II • The two cell divisions result in four daughter cells, rather than the two daughter cells in ...
Novel cryptic chromosomal rearrangements in childhood acute
... A cryptic translocation t(7;11)(q35;q24) was detected in a patient with T-ALL in association with a recurrent t(1;14)(p32;q11), a second cryptic translocation t(6;10) (q25;q24), and an ins(9;10)(p22;?). FISH analysis showed rearrangement of a BAC clone spanning the TCRB locus and led us to assume th ...
... A cryptic translocation t(7;11)(q35;q24) was detected in a patient with T-ALL in association with a recurrent t(1;14)(p32;q11), a second cryptic translocation t(6;10) (q25;q24), and an ins(9;10)(p22;?). FISH analysis showed rearrangement of a BAC clone spanning the TCRB locus and led us to assume th ...
Gene Signal Estimates from Exon Arrays v1.0
... containing probe sets that interrogate exons of RefSeq (Pruitt and Maglott 2001) genes, mRNAs and ESTs from GenBank (Benson et al. 1999), it also contains probe sets for exons predicted by ab-initio gene finders such as GENSCAN (Burge and Karlin 1997), TWINSCAN (Korf et al. 2001), geneid (Parra et a ...
... containing probe sets that interrogate exons of RefSeq (Pruitt and Maglott 2001) genes, mRNAs and ESTs from GenBank (Benson et al. 1999), it also contains probe sets for exons predicted by ab-initio gene finders such as GENSCAN (Burge and Karlin 1997), TWINSCAN (Korf et al. 2001), geneid (Parra et a ...
The genetic causes of convergent evolution
... Another challenge results from the fact that most evolved phenotypic variation is caused by genetic differences at multiple loci. Quantitative trait locus (QTL) mapping can be used as a first step to identify broad genomic regions that contribute to phenotypic differences, but direct inference of pa ...
... Another challenge results from the fact that most evolved phenotypic variation is caused by genetic differences at multiple loci. Quantitative trait locus (QTL) mapping can be used as a first step to identify broad genomic regions that contribute to phenotypic differences, but direct inference of pa ...
Press - APHA.com
... pair. Basically, each pair of genes codes for a specific job. A pair of genes can control something as obvious as whether or not a cow will have horns, or it may be as subtle as coding for a specific portion of a bimolecular molecule, or controlling the function of other genes. During the cell divis ...
... pair. Basically, each pair of genes codes for a specific job. A pair of genes can control something as obvious as whether or not a cow will have horns, or it may be as subtle as coding for a specific portion of a bimolecular molecule, or controlling the function of other genes. During the cell divis ...
Full-Text PDF
... Recent orthology studies now show that nearly 1000 yeast genes are associated with human diseases [51], and in many cases the mammalian ortholog is functional and complements the yeast deletion mutant. (v) The “omics” approaches. Not only has the thorough annotation of the S. cerevisiae genome, perf ...
... Recent orthology studies now show that nearly 1000 yeast genes are associated with human diseases [51], and in many cases the mammalian ortholog is functional and complements the yeast deletion mutant. (v) The “omics” approaches. Not only has the thorough annotation of the S. cerevisiae genome, perf ...
Identifying the genomic determinants of aging and longevity in
... Family-based cohorts: Family-based longevity studies consist of nonagenarians/centenarians (siblings) and their middle-aged offspring. The controls used in these studies are either (age-matched) random individuals from the general population or spouses of the offspring of the long-lived individuals. ...
... Family-based cohorts: Family-based longevity studies consist of nonagenarians/centenarians (siblings) and their middle-aged offspring. The controls used in these studies are either (age-matched) random individuals from the general population or spouses of the offspring of the long-lived individuals. ...
Genetic studies of psoriasis and psoriatic arthritis
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
Linkage analysis the basic concepts
... General Usage: determine ‘genetic distance’ between 2 or more loci; genetic distance determined by θ MAKE GENETIC MAPS --First Human Genetic Map was completed in 1987 with 440 markers organized into 23 linkage groups. Locations between markers determined via linkage LOCATE DISEASE GENES --Locate dis ...
... General Usage: determine ‘genetic distance’ between 2 or more loci; genetic distance determined by θ MAKE GENETIC MAPS --First Human Genetic Map was completed in 1987 with 440 markers organized into 23 linkage groups. Locations between markers determined via linkage LOCATE DISEASE GENES --Locate dis ...
Introduction to GO Annotation
... • Comparisons between species – Gets powerful if we have broader species coverage ...
... • Comparisons between species – Gets powerful if we have broader species coverage ...
genetics - Liceocopernico.it
... Some exposure to college-level or university-level biology is desirable before embarking on the study of genetics. In this volume, however, basic biological principles (such as cell structures and functions) are reviewed to provide a common base of essential background information. The quantitative ...
... Some exposure to college-level or university-level biology is desirable before embarking on the study of genetics. In this volume, however, basic biological principles (such as cell structures and functions) are reviewed to provide a common base of essential background information. The quantitative ...
North Kitsap High School PAL Program
... what a gene pool is, state what determines how a phenotype is expressed, explain how natural selection affects single-gene and polygenic traits, describe genetic drift, list five conditions needed to maintain genetic equilibrium, identify the conditions necessary for a new species to evolve. (17 sec ...
... what a gene pool is, state what determines how a phenotype is expressed, explain how natural selection affects single-gene and polygenic traits, describe genetic drift, list five conditions needed to maintain genetic equilibrium, identify the conditions necessary for a new species to evolve. (17 sec ...
The SELF-PRUNING gene of tomato regulates
... ultimately controlled by the activity of the shoot apical meristem (Sussex, 1989). The growth habit of plants is defined by the pattern of vegetative and reproductive appendages arising along the shoot axes and by the way in which lateral branches arise. It determines, therefore, yield and other agr ...
... ultimately controlled by the activity of the shoot apical meristem (Sussex, 1989). The growth habit of plants is defined by the pattern of vegetative and reproductive appendages arising along the shoot axes and by the way in which lateral branches arise. It determines, therefore, yield and other agr ...
Biology 409 - CSU, Chico
... Provide an explanation for the origin of repetitive sequences in the human genome and summarize functions for repetitive DNA in chromosome functioning. ...
... Provide an explanation for the origin of repetitive sequences in the human genome and summarize functions for repetitive DNA in chromosome functioning. ...
Widespread Macromolecular Interaction Perturbations in Human
... cancer susceptibility and heart, respiratory, and neurological diseases. We retrieved from HGMD (Stenson et al., 2014) a list of 16,400 mutations affecting over 1,200 genes for which we have a wild-type (WT) open-reading frame (ORF) clone in our human ‘‘ORFeome’’ collection (Yang et al., 2011) and ...
... cancer susceptibility and heart, respiratory, and neurological diseases. We retrieved from HGMD (Stenson et al., 2014) a list of 16,400 mutations affecting over 1,200 genes for which we have a wild-type (WT) open-reading frame (ORF) clone in our human ‘‘ORFeome’’ collection (Yang et al., 2011) and ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse