Slides: background and project plan
... • Each cell contains an identical copy of the whole genome - but utilizes only a subset of the genes to perform diverse, unique tasks • Most genes are highly regulated – their expression is limited to specific tissues, developmental stages, physiological condition • Main regulatory mechanism – trans ...
... • Each cell contains an identical copy of the whole genome - but utilizes only a subset of the genes to perform diverse, unique tasks • Most genes are highly regulated – their expression is limited to specific tissues, developmental stages, physiological condition • Main regulatory mechanism – trans ...
THE EFFECT OF INBREEDING ON THE VARIATION DUE TO
... of the ith and jth lines and aij is the interaction term, the special combining ability. The term ‘‘ top-cross ” refers to the crosses made between a line and a sample of individuals from the random-bred population. The average topcrossing performance of a line should be equal to the general combini ...
... of the ith and jth lines and aij is the interaction term, the special combining ability. The term ‘‘ top-cross ” refers to the crosses made between a line and a sample of individuals from the random-bred population. The average topcrossing performance of a line should be equal to the general combini ...
A global picture of tRNA genes in plant genomes
... are found in animals but are absent in fungi or higher plants. However, Sec-containing proteins were found in the green algae C. reinhardtii (Novoselov et al., 2002). As incorporation of selenocysteine into proteins requires a specific tRNA designated tRNASec, such a tRNA is present in C. reinhardti ...
... are found in animals but are absent in fungi or higher plants. However, Sec-containing proteins were found in the green algae C. reinhardtii (Novoselov et al., 2002). As incorporation of selenocysteine into proteins requires a specific tRNA designated tRNASec, such a tRNA is present in C. reinhardti ...
Interval mapping of QTLs controlling yield
... (LG I, II, V, VI and VII). The LOD values of all QTLs mapped were low (Table 4) except one: 2sn-4 (LOD = 4.0). The portion of total trait variance explained (VE) was the highest for two QTLs: 2sn-3 (VE = 44.3%) and 2sn-4 (VE = 55.9%). For most of QTLs mapped, the additive effect of the allele from t ...
... (LG I, II, V, VI and VII). The LOD values of all QTLs mapped were low (Table 4) except one: 2sn-4 (LOD = 4.0). The portion of total trait variance explained (VE) was the highest for two QTLs: 2sn-3 (VE = 44.3%) and 2sn-4 (VE = 55.9%). For most of QTLs mapped, the additive effect of the allele from t ...
A/a · B/b
... A secondary cure would result if all galactose and lactose were removed from the diet. The disorder would be expected not to be dominant, because one good copy of the gene should allow for at least some, if not all, breakdown of galactose. In fact, the disorder is recessive. ...
... A secondary cure would result if all galactose and lactose were removed from the diet. The disorder would be expected not to be dominant, because one good copy of the gene should allow for at least some, if not all, breakdown of galactose. In fact, the disorder is recessive. ...
MAK, a computational tool kit for automated MITE
... thought to be related to ancestral elements that bear similar TIRs and subterminal regions and are (or were) capable of coding for transposase-like proteins (20,23,24,28), the majority of MITE families lack such links. Since different MITE families may be derived from different founder elements, a l ...
... thought to be related to ancestral elements that bear similar TIRs and subterminal regions and are (or were) capable of coding for transposase-like proteins (20,23,24,28), the majority of MITE families lack such links. Since different MITE families may be derived from different founder elements, a l ...
recommended breeding policy for the maine
... are probably New England barn cats which were taken to farm shows by their owners. The Maine Coon is now well established in the UK, and was first registered in 1984 and gained championship status in 1994, having originally been shown on exhibition. There has now been over 25 years of breeding which ...
... are probably New England barn cats which were taken to farm shows by their owners. The Maine Coon is now well established in the UK, and was first registered in 1984 and gained championship status in 1994, having originally been shown on exhibition. There has now been over 25 years of breeding which ...
A CRISPR-based yeast two-hybrid system for investigating
... integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, which contains the reporter genes HIS3 and LacZ with 4 and 8 LexA-binding sites inserted in their promoters, respectively6. While several adaptations of the CRISPR/C ...
... integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, which contains the reporter genes HIS3 and LacZ with 4 and 8 LexA-binding sites inserted in their promoters, respectively6. While several adaptations of the CRISPR/C ...
FLUORESCENT PROTEIN IN Escherichia coli
... The discovery of penicillin in 1928 by Sir Alexander Fleming was a huge breakthrough and became a shift in paradigm to how infections were treated. Since then many other antiobiotics were developed, e.g. streptomycin against tuberculosis. This meant that the leading cause of death changed from being ...
... The discovery of penicillin in 1928 by Sir Alexander Fleming was a huge breakthrough and became a shift in paradigm to how infections were treated. Since then many other antiobiotics were developed, e.g. streptomycin against tuberculosis. This meant that the leading cause of death changed from being ...
Kein Folientitel
... genetic information called the “genome”. This information is encoded in 4 kinds of nucleobases: ...
... genetic information called the “genome”. This information is encoded in 4 kinds of nucleobases: ...
DNA Methylation Analysis
... Database9 (Genome Build 36). Additional markers provide increased resolution focused on 144 established cancer genes that have shown differential methylation patterns. To ensure the most important loci were represented, Illumina designed markers to cover nearly 1,000 cancer-related genes described i ...
... Database9 (Genome Build 36). Additional markers provide increased resolution focused on 144 established cancer genes that have shown differential methylation patterns. To ensure the most important loci were represented, Illumina designed markers to cover nearly 1,000 cancer-related genes described i ...
BIO 201 - Southern Union State Community College
... SLO Course Student Learning Outcomes / Competencies / Objectives 1.Describe the structure of the neurons 2. Distinguish between types of neurons 3. Explain how receptors function and how sensations are identified 4. Identify the functions and parts of the brain 5. Describe the anatomy and distributi ...
... SLO Course Student Learning Outcomes / Competencies / Objectives 1.Describe the structure of the neurons 2. Distinguish between types of neurons 3. Explain how receptors function and how sensations are identified 4. Identify the functions and parts of the brain 5. Describe the anatomy and distributi ...
A B - Drug Metabolism and Disposition
... c.449TG>A could substantially affect drug metabolism in monkeys, the origin of animals used is one of the most important factors for a successful study on drug metabolism. Inactivation of species-specific genes such as CYP2C76 could lead to a better animal model in monkeys. However, the techniques o ...
... c.449TG>A could substantially affect drug metabolism in monkeys, the origin of animals used is one of the most important factors for a successful study on drug metabolism. Inactivation of species-specific genes such as CYP2C76 could lead to a better animal model in monkeys. However, the techniques o ...
A CRISPR-based yeast two-hybrid system for investigating
... integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, which contains the reporter genes HIS3 and LacZ with 4 and 8 LexA-binding sites inserted in their promoters, respectively6. While several adaptations of the CRISPR/C ...
... integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, which contains the reporter genes HIS3 and LacZ with 4 and 8 LexA-binding sites inserted in their promoters, respectively6. While several adaptations of the CRISPR/C ...
Neutral Theory
... suggested in Haldane 1957 and is not necessarily inconsistent with the observed nucleotide substitution rate. A similar argument is made in King 1967, Milkman 1967, and Sved, et al. 1967 that the observation in Lewontin and Hubby 1966 (cited under Origin of the Theory) of a high heterozygosity of fr ...
... suggested in Haldane 1957 and is not necessarily inconsistent with the observed nucleotide substitution rate. A similar argument is made in King 1967, Milkman 1967, and Sved, et al. 1967 that the observation in Lewontin and Hubby 1966 (cited under Origin of the Theory) of a high heterozygosity of fr ...
Chapter 15
... • Offspring with this condition have an abnormal number of a particular chromosome – A monosomic zygote has only one copy of a particular chromosome – A trisomic zygote has three copies of a particular chromosome Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
... • Offspring with this condition have an abnormal number of a particular chromosome – A monosomic zygote has only one copy of a particular chromosome – A trisomic zygote has three copies of a particular chromosome Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
Wingless can bring about a mesoderm-to
... have come from there. Our results show that wingless must be produced in the mesoderm and still be active there at least one hour after gastrulation (see below). This was not clear before: wingless Fig. 1. (A) Dorsal view of a mosaic in which part of the mesoderm, both left and right, has been forme ...
... have come from there. Our results show that wingless must be produced in the mesoderm and still be active there at least one hour after gastrulation (see below). This was not clear before: wingless Fig. 1. (A) Dorsal view of a mosaic in which part of the mesoderm, both left and right, has been forme ...
RNA interference pathways display high rates of adaptive protein
... lower than 5, but we reduced this threshold to 2 for the low-coverage B. mandarina. After mapping and filtering sites we created two randomly resolved pseudohaplotype sequences per individual (i.e. without any linkage information) from the sites that remained, and these were used for downstream anal ...
... lower than 5, but we reduced this threshold to 2 for the low-coverage B. mandarina. After mapping and filtering sites we created two randomly resolved pseudohaplotype sequences per individual (i.e. without any linkage information) from the sites that remained, and these were used for downstream anal ...
Pourcel et al., Microbiology 2005
... In all three sequenced genomes, three CRISPR elements are found. One of them, called here YP1, is associated with the cas1 and cas3 genes and is located in the vicinity of the replication terminus (Fig. 1). The relative position of YP1, YP2 and YP3 varies in the three genomes due to large-scale DNA ...
... In all three sequenced genomes, three CRISPR elements are found. One of them, called here YP1, is associated with the cas1 and cas3 genes and is located in the vicinity of the replication terminus (Fig. 1). The relative position of YP1, YP2 and YP3 varies in the three genomes due to large-scale DNA ...
Determining the epitope dominance on the capsid of a SAT2 fmdv by mutational analysis, P.A.Opperman
... SD→PE and the KD→RN mutations in 1B TKHK→IKHK mutation in the βG-βH loop of 1D HAD→YAS mutation at the C-terminus of 1D Slight increase in neutralizing titre against the SAT2/KNP/19/89 antiserum and not significantly reduced against SAT2/ZIM/7/83 HNN→NKG and the AFA→TFN mutations in the 1D ...
... SD→PE and the KD→RN mutations in 1B TKHK→IKHK mutation in the βG-βH loop of 1D HAD→YAS mutation at the C-terminus of 1D Slight increase in neutralizing titre against the SAT2/KNP/19/89 antiserum and not significantly reduced against SAT2/ZIM/7/83 HNN→NKG and the AFA→TFN mutations in the 1D ...
European Journal of Soil Science
... chemical data of the fertilized plot were almost identical to those of the control (see Rösch & Bothe, 2005). To avoid border effects, fertilizer was added to a 4 × 4 m area containing the 2 × 2 m treatment area. For this, 625 mmol per m2 of pulverized NH4 NO3 was manually dispersed as evenly as po ...
... chemical data of the fertilized plot were almost identical to those of the control (see Rösch & Bothe, 2005). To avoid border effects, fertilizer was added to a 4 × 4 m area containing the 2 × 2 m treatment area. For this, 625 mmol per m2 of pulverized NH4 NO3 was manually dispersed as evenly as po ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse