Marker-Assisted Selection for Disease Resistance in Wheat and
... Resistance locus/QTL that do not provide a complete resistance irrespective of the mode of its inheritance. QTL are always partially expressed, but some monogenically inherited resistance genes also show partial expression, e.g., Lr34, Yr36, and Pch1. The term partial resistance, often used synonymo ...
... Resistance locus/QTL that do not provide a complete resistance irrespective of the mode of its inheritance. QTL are always partially expressed, but some monogenically inherited resistance genes also show partial expression, e.g., Lr34, Yr36, and Pch1. The term partial resistance, often used synonymo ...
Fragaria multicipita - DigitalCommons@University of Nebraska
... standards used were PhiX174 RF HaeIII digest (Life Technologies) and 1.6 kb ladder (Fermentas AB, Vilnius, Lithuania). RFLP patterns were compared with those previously published (Davis et al., 1997; Jomantiene et al. 1998a,b, 2002; Lee et al. 1998). Phytoplasma 16S rRNA group and subgroup designati ...
... standards used were PhiX174 RF HaeIII digest (Life Technologies) and 1.6 kb ladder (Fermentas AB, Vilnius, Lithuania). RFLP patterns were compared with those previously published (Davis et al., 1997; Jomantiene et al. 1998a,b, 2002; Lee et al. 1998). Phytoplasma 16S rRNA group and subgroup designati ...
Technical standards and guidelines for spinal muscular atrophy testing
... The SMA gene is within a complex region containing multiple repetitive and inverted sequences.5 The SMN gene (Entrez Gene ID number 6606) comprises nine exons with a stop codon present near the end of exon 7.6 Two inverted SMN copies are present: the telomeric or SMN1 gene, which is the SMA-determin ...
... The SMA gene is within a complex region containing multiple repetitive and inverted sequences.5 The SMN gene (Entrez Gene ID number 6606) comprises nine exons with a stop codon present near the end of exon 7.6 Two inverted SMN copies are present: the telomeric or SMN1 gene, which is the SMA-determin ...
Identification of Transcription Factors GZF3, RFX1, Orf19.3928 as
... Candida that exists as part of our natural flora usually does not cause disease due to competition with the many other commensal organisms that exist in our microbiome. The use of broad spectrum antibiotics, while effectively eliminating the desired target organism responsible for disease, may also ...
... Candida that exists as part of our natural flora usually does not cause disease due to competition with the many other commensal organisms that exist in our microbiome. The use of broad spectrum antibiotics, while effectively eliminating the desired target organism responsible for disease, may also ...
Genome Biology - Department of Computer Science and
... regions from ChIP-chip experiments [23]. Since TFs bind to the upstream sequence of ORFs, we focused on histone modification signals 1kb flanking translation start sites (ATGs), because TFBSs were enriched in these regions. For TF PSSMs, 2 independent sets were obtained from previous studies. One se ...
... regions from ChIP-chip experiments [23]. Since TFs bind to the upstream sequence of ORFs, we focused on histone modification signals 1kb flanking translation start sites (ATGs), because TFBSs were enriched in these regions. For TF PSSMs, 2 independent sets were obtained from previous studies. One se ...
MeCP2 mutations in children with and without
... X-inactivation have been shown for several asymptomatic carriers of MeCP2 mutations.7,14,17,18,28 In these cases, the pattern of X-inactivation most likely protected the mutation carriers from expression of the disease by preferential inactivation of the mutant MeCP2 allele. We report a genotype and ...
... X-inactivation have been shown for several asymptomatic carriers of MeCP2 mutations.7,14,17,18,28 In these cases, the pattern of X-inactivation most likely protected the mutation carriers from expression of the disease by preferential inactivation of the mutant MeCP2 allele. We report a genotype and ...
Direct control of shoot meristem activity by a cytokinin
... The growth of plants depends on continuous function of the meristems. Shoot meristems are responsible for all the post-embryonic aerial organs, such as leaves, stems and flowers1. It has been assumed that the phytohormone cytokinin has a positive role in shoot meristem function2–4. A severe reductio ...
... The growth of plants depends on continuous function of the meristems. Shoot meristems are responsible for all the post-embryonic aerial organs, such as leaves, stems and flowers1. It has been assumed that the phytohormone cytokinin has a positive role in shoot meristem function2–4. A severe reductio ...
Large-Scale Chromosomal Changes
... translocation) might cause cancer in somatic cells, such as Burkitt’s lymphoma and chronic myologenous leukemia. In general, any chromosomal rearrangement that changes the regulatory environment of a gene could lead to cancer. Other causes would be based on a mutation in a gene which might control c ...
... translocation) might cause cancer in somatic cells, such as Burkitt’s lymphoma and chronic myologenous leukemia. In general, any chromosomal rearrangement that changes the regulatory environment of a gene could lead to cancer. Other causes would be based on a mutation in a gene which might control c ...
what is alignment? - UWI St. Augustine
... • Matrix Bias: is added to every cell of the scoring matrix and decides the size of the break. Also ...
... • Matrix Bias: is added to every cell of the scoring matrix and decides the size of the break. Also ...
some inconvenient truths about sex chromosome dosage
... the heterogametic sex, to increase transcription of the single X or Z chromosome to that level expected from a diploid complement. Empirical tests of dosage compensation often assess the gene expression differences for X- or Z-linked genes between the sexes, with dosage compensation concluded when m ...
... the heterogametic sex, to increase transcription of the single X or Z chromosome to that level expected from a diploid complement. Empirical tests of dosage compensation often assess the gene expression differences for X- or Z-linked genes between the sexes, with dosage compensation concluded when m ...
Pharmacology and Toxicology, Pharmaceutical Chemistry
... E and protease amylosacchariticus. The homology of the total amino acid residues between protease NAT and protease. They have drawn using the program Discovery Studio [38]. Relative locations of the catalytic residues and mutations are indicated [39]. Protein engineering Many pharmaceutical industri ...
... E and protease amylosacchariticus. The homology of the total amino acid residues between protease NAT and protease. They have drawn using the program Discovery Studio [38]. Relative locations of the catalytic residues and mutations are indicated [39]. Protein engineering Many pharmaceutical industri ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... VEGF−1154G/A was not associated with RA among Bahraini women, in agreement with a recent study on Chinese Han women(28), and a large meta- analysis involving 2813 cases and 2830 controls (29). In contrast, studies on Koreans(26) and Caucasians (30) indicated association between−1154G/A and RA risk, ...
... VEGF−1154G/A was not associated with RA among Bahraini women, in agreement with a recent study on Chinese Han women(28), and a large meta- analysis involving 2813 cases and 2830 controls (29). In contrast, studies on Koreans(26) and Caucasians (30) indicated association between−1154G/A and RA risk, ...
meiosis
... – If pea plant, for example, produces 14 chromosomes – Gametes would each contain 14 chromosomes – Each offspring would have 28 – Offspring of next generation would have 56 ...
... – If pea plant, for example, produces 14 chromosomes – Gametes would each contain 14 chromosomes – Each offspring would have 28 – Offspring of next generation would have 56 ...
Increased sex chromosome expression and epigenetic
... polymerase II, and are enriched for several repressive chromatin marks present on the sex body, including histone H3 dimethylated at lysine 9 (H3K9me2) and CBX1 (chromobox protein homolog 1, previously known as HP1) (Baarends et al., 2007; Greaves et al., 2006; Khalil et al., 2004; Namekawa et al., ...
... polymerase II, and are enriched for several repressive chromatin marks present on the sex body, including histone H3 dimethylated at lysine 9 (H3K9me2) and CBX1 (chromobox protein homolog 1, previously known as HP1) (Baarends et al., 2007; Greaves et al., 2006; Khalil et al., 2004; Namekawa et al., ...
genes code for ion channels, but 2 channelopathies (MASS1
... The clinical spectrum of SCN1A mutations ranges from febrile seizures, febrile seizures plus, a mild and a classical form of severe myoclonic epilepsy in infancy (Dravet syndrome). (Berten PGM et al. Clinical correlations of mutations in the SCN1A gene: from febrile seizures to severe myoclonic epil ...
... The clinical spectrum of SCN1A mutations ranges from febrile seizures, febrile seizures plus, a mild and a classical form of severe myoclonic epilepsy in infancy (Dravet syndrome). (Berten PGM et al. Clinical correlations of mutations in the SCN1A gene: from febrile seizures to severe myoclonic epil ...
Bcl-2–Modifying Factor Induces Renal Proximal Tubular
... were analyzed by computer with R statistical language (version 2.51). AffylmGUI (version 1.10.5) software and the LIMMA package (version 2.10.5) of the Bioconductor Library (release 2.0) were used for data analysis (27–30). The GCRMA (Gene Chip Robust Multi-array Average) algorithm was used for back ...
... were analyzed by computer with R statistical language (version 2.51). AffylmGUI (version 1.10.5) software and the LIMMA package (version 2.10.5) of the Bioconductor Library (release 2.0) were used for data analysis (27–30). The GCRMA (Gene Chip Robust Multi-array Average) algorithm was used for back ...
"Tooth Agenesis". - Thimios Mitsiadis
... sequences found in humans with tooth agenesis, it can be predicted that the consequences of the genetic defects are either severely truncated proteins or proteins with a deficient capacity to bind to DNA. Thus, in a heterozygous condition where one allele is mutated whereas the other allele is normal ...
... sequences found in humans with tooth agenesis, it can be predicted that the consequences of the genetic defects are either severely truncated proteins or proteins with a deficient capacity to bind to DNA. Thus, in a heterozygous condition where one allele is mutated whereas the other allele is normal ...
Collagens, modifying enzymes and their mutations in humans, flies
... Figure 1. Members of the collagen superfamily and their known supramolecular assemblies. The collagen superfamily can be divided into nine families on the basis of the supramolecular assemblies and other features of its members: (a) fibril-forming collagens; (b) fibril-associated collagens with inte ...
... Figure 1. Members of the collagen superfamily and their known supramolecular assemblies. The collagen superfamily can be divided into nine families on the basis of the supramolecular assemblies and other features of its members: (a) fibril-forming collagens; (b) fibril-associated collagens with inte ...
Developmental and genetic disorders in
... The most common cause of male infertility is idiopathic. Fresh insights based on genetic and molecular analysis of the human genome permit classification of formerly unexplained disorders in spermatogenesis. In this article, we review new procedures that expand diagnostic and therapeutic approaches ...
... The most common cause of male infertility is idiopathic. Fresh insights based on genetic and molecular analysis of the human genome permit classification of formerly unexplained disorders in spermatogenesis. In this article, we review new procedures that expand diagnostic and therapeutic approaches ...
Estimating the Rate of Adaptive Molecular Evolution When the
... sequence datasets of multiple genes, and now with the complete genome sequences of multiple individuals. These datasets enable tests for excess of nucleotide substitutions between species, which can be attributed to adaptive evolution. Fay et al. (2001) (FWW2001) proposed an extension of the McDonal ...
... sequence datasets of multiple genes, and now with the complete genome sequences of multiple individuals. These datasets enable tests for excess of nucleotide substitutions between species, which can be attributed to adaptive evolution. Fay et al. (2001) (FWW2001) proposed an extension of the McDonal ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse