Twinning and Embryonic Left-Right Asymmetry
... body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exhibits when viewed from the outside. Interestingly though, the internal organs of most animals reveal an individually and evolutionarily conserved asymme ...
... body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exhibits when viewed from the outside. Interestingly though, the internal organs of most animals reveal an individually and evolutionarily conserved asymme ...
Gene Selection For A Discriminant Microarray Data Analysis
... Breast Cancer Data Microarray experiments were carried out before and after chemotherapy on the same patient. Since these two samples are not independent, usual logistic regression can not be applied. We use paired case-control logistic regression. Two features: (1) each pair is essentially ...
... Breast Cancer Data Microarray experiments were carried out before and after chemotherapy on the same patient. Since these two samples are not independent, usual logistic regression can not be applied. We use paired case-control logistic regression. Two features: (1) each pair is essentially ...
Melanocortin 1 recep
... Given the clear association between the 24 bp deletion and melanism in the British grey squirrel, we extended the study of variations in the MC1R to two other squirrel species with melanic variants, the fox squirrel (Sciurus niger) and the red squirrel (Sciurus vulgaris). All three squirrel species ...
... Given the clear association between the 24 bp deletion and melanism in the British grey squirrel, we extended the study of variations in the MC1R to two other squirrel species with melanic variants, the fox squirrel (Sciurus niger) and the red squirrel (Sciurus vulgaris). All three squirrel species ...
Set - people.vcu.edu
... • The interface facilitates operations on sets of genes and sequences • The interface puts at your disposal powerful tools (that already exist), without the need to figure out a different computer environment • Taken together, these capabilities make possible a focus by those not particularly adept ...
... • The interface facilitates operations on sets of genes and sequences • The interface puts at your disposal powerful tools (that already exist), without the need to figure out a different computer environment • Taken together, these capabilities make possible a focus by those not particularly adept ...
Molecular Mechanisms of Floral Boundary Formation in Arabidopsis
... The mutant in MIR164c has extra petals in early-arising flowers that were proposed to be associated with the additional boundary domains formed in the second whorl [67]. The petal-specific function of EEP1 is controlled in part by the C2H2 zinc finger transcription factor RABITT EARS (RBE) [8]. RBE ...
... The mutant in MIR164c has extra petals in early-arising flowers that were proposed to be associated with the additional boundary domains formed in the second whorl [67]. The petal-specific function of EEP1 is controlled in part by the C2H2 zinc finger transcription factor RABITT EARS (RBE) [8]. RBE ...
Quantitative Genetics
... individuals of exactly identical genotype will be placed in many different, very carefully controlled environments. Careful analysis of the norm of reaction may, perhaps, tell us a little bit about how the genes responsible for that quantitative trait interact with the environment in that trait’s de ...
... individuals of exactly identical genotype will be placed in many different, very carefully controlled environments. Careful analysis of the norm of reaction may, perhaps, tell us a little bit about how the genes responsible for that quantitative trait interact with the environment in that trait’s de ...
6 Gene Interaction
... b. The progeny of the cross Cb/Cs Cb/Cc will be 3/4 black (1/4 Cb/Cb, 1/4 Cb/Cc, 1/4 Cb/Cs) : 1/4 sepia (Cs/Cc). The progeny of the cross Cb/Ca (or Cb/Cc) Cb/Cc will be 3/4 black: 1/4 cream. 23. In a maternity ward, four babies become accidentally mixed up. The ABO types of the four babies are k ...
... b. The progeny of the cross Cb/Cs Cb/Cc will be 3/4 black (1/4 Cb/Cb, 1/4 Cb/Cc, 1/4 Cb/Cs) : 1/4 sepia (Cs/Cc). The progeny of the cross Cb/Ca (or Cb/Cc) Cb/Cc will be 3/4 black: 1/4 cream. 23. In a maternity ward, four babies become accidentally mixed up. The ABO types of the four babies are k ...
Periodic Selection and Ecological Diversity in Bacteria
... undergoes recombination at a rate of 1.2 × 10-6 per individual per generation, which is 3.6 times the mutation rate.11,16 While recombination in bacteria is rare, it is also promiscuous; bacteria are not fastidious about their choice of sexual partners. Homologous recombination occurs even between o ...
... undergoes recombination at a rate of 1.2 × 10-6 per individual per generation, which is 3.6 times the mutation rate.11,16 While recombination in bacteria is rare, it is also promiscuous; bacteria are not fastidious about their choice of sexual partners. Homologous recombination occurs even between o ...
What are enzymes?
... Proteins can be split into two groups: structural proteins and biologically-active proteins. Structural proteins are the main constituents of our bodies e.g. collagen, which is found in bones, tendons and ligaments, and keratin, the protein of nails, hair and feathers. Biologically-active proteins c ...
... Proteins can be split into two groups: structural proteins and biologically-active proteins. Structural proteins are the main constituents of our bodies e.g. collagen, which is found in bones, tendons and ligaments, and keratin, the protein of nails, hair and feathers. Biologically-active proteins c ...
Help Me Understand Genetics
... DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where ...
... DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where ...
mic.sgmjournals.org
... was observed and we focused our attention on lactate synthesis. Lactate synthesis was due to the ldh-encoded L-lactate dehydrogenase (Ldh). Features of Ldh activity and ldh transcription were analysed. The ldh gene was shown to be regulated at the transcriptional level by SugR, a pleiotropic transcr ...
... was observed and we focused our attention on lactate synthesis. Lactate synthesis was due to the ldh-encoded L-lactate dehydrogenase (Ldh). Features of Ldh activity and ldh transcription were analysed. The ldh gene was shown to be regulated at the transcriptional level by SugR, a pleiotropic transcr ...
INHERITANCE OF POLYDACTYLY IN THE MOUSE
... From generation 6 and on, excluding mating 8-3, the percentage of polydactyly from Poly x Poly matings is 84.5 pefcent (50 0 N, 291 0 P, 58 8 N, 300 8 P, total 699)#The frequencies for each generation change, those before generation 6 being notably lower than thqse for generation 6 and later (table ...
... From generation 6 and on, excluding mating 8-3, the percentage of polydactyly from Poly x Poly matings is 84.5 pefcent (50 0 N, 291 0 P, 58 8 N, 300 8 P, total 699)#The frequencies for each generation change, those before generation 6 being notably lower than thqse for generation 6 and later (table ...
LINKAGE AND MAPPING IN EUKARYOTES
... fter Sutton suggested the chromosomal theory of inheritance in 1903, evidence accumulated that genes were located on chromosomes. For example, Morgan showed by an analysis of inheritance patterns that the white-eye locus in Drosophila is located on the X chromosome. Given that any organism has many ...
... fter Sutton suggested the chromosomal theory of inheritance in 1903, evidence accumulated that genes were located on chromosomes. For example, Morgan showed by an analysis of inheritance patterns that the white-eye locus in Drosophila is located on the X chromosome. Given that any organism has many ...
Arsenite as an Electron Donor for Anoxygenic Photosynthesis
... indicating that arxA-type arsenite oxidases may be widespread in nature. Here we report the further characterization of strain PHS-1 and the isolation of two new strains of Ectothiorhodospira: strain MLW-1, isolated from shoreline sediments of Mono Lake and strain BSL-9, isolated from Big Soda Lake ...
... indicating that arxA-type arsenite oxidases may be widespread in nature. Here we report the further characterization of strain PHS-1 and the isolation of two new strains of Ectothiorhodospira: strain MLW-1, isolated from shoreline sediments of Mono Lake and strain BSL-9, isolated from Big Soda Lake ...
Evidence for Mitotic Crossing-over During the
... diploidswere still heterozygous sincethe recessive alleles could be recovered on haploidization. If these diploids arose in the manner suggested by Katz & Sussman (1972) for their cycloheximide resistant diploids, namely a loss and reduplication of a complete chromosome, then all the markers on chro ...
... diploidswere still heterozygous sincethe recessive alleles could be recovered on haploidization. If these diploids arose in the manner suggested by Katz & Sussman (1972) for their cycloheximide resistant diploids, namely a loss and reduplication of a complete chromosome, then all the markers on chro ...
PDF
... In gametophytic apomixis, the unreduced embryo sac may arise from a somatic nucellar cell which acquires the developmental program of a functional megaspore, a mechanism referred to as apospory. Alternatively, if the embryo sac forms from a megaspore mother cell with suppressed or modified meiosis, ...
... In gametophytic apomixis, the unreduced embryo sac may arise from a somatic nucellar cell which acquires the developmental program of a functional megaspore, a mechanism referred to as apospory. Alternatively, if the embryo sac forms from a megaspore mother cell with suppressed or modified meiosis, ...
Modifying effects of phenotypic plasticity on interactions among
... once induced by an environmental cue becomes canalized, so that it is expressed even when the environmental cue is removed (reviewed by West-Eberhard, 2003; Crispo, 2007). Plasticity could be lost due to neutral processes (i.e. drift) if populations are located in homogeneous environments (i.e. plas ...
... once induced by an environmental cue becomes canalized, so that it is expressed even when the environmental cue is removed (reviewed by West-Eberhard, 2003; Crispo, 2007). Plasticity could be lost due to neutral processes (i.e. drift) if populations are located in homogeneous environments (i.e. plas ...
Retrotransposon-Mediated Fgf5go-Utr Mutant Mice
... the Fgf5go-Utr allele is a novel mutation of Fgf5 mediated by a retrotransposon. Although previous studies have demonstrated that FGF5 is an important factor in regulation of the hair follicle cycle, it is not clear whether or not FGF5 is involved in human diseases. Recently, a genome-wide associati ...
... the Fgf5go-Utr allele is a novel mutation of Fgf5 mediated by a retrotransposon. Although previous studies have demonstrated that FGF5 is an important factor in regulation of the hair follicle cycle, it is not clear whether or not FGF5 is involved in human diseases. Recently, a genome-wide associati ...
The Human Genome Project: Genetic Screening and the
... of scientific advancements yielded by the Human Genome Project and how this science supports the state's interest in public genetic health, it is necessary to have a basic understanding of genetics and of the potential of advancements in genetic technology. The science of genetics provides the frame ...
... of scientific advancements yielded by the Human Genome Project and how this science supports the state's interest in public genetic health, it is necessary to have a basic understanding of genetics and of the potential of advancements in genetic technology. The science of genetics provides the frame ...
Probable presence of an ubiquitous cryptic mitochondrial gene on
... activity in protein synthesis [24]. For example, the usage frequencies of amino acid cognates in regular primate mitochondrial ORFs coevolve with various antisense tRNA properties that are required for proper activity in translation [24]. These results were also confirmed by the association between ...
... activity in protein synthesis [24]. For example, the usage frequencies of amino acid cognates in regular primate mitochondrial ORFs coevolve with various antisense tRNA properties that are required for proper activity in translation [24]. These results were also confirmed by the association between ...
Multiple Quantitative Trait Loci Modify Cochlear Hair Cell
... Dominant mutations of transmembrane channel-like gene 1 (TMC1) cause progressive sensorineural hearing loss in humans and Beethoven (Tmc1Bth/1) mice. Here we show that Tmc1Bth/1 mice on a C3HeB/FeJ strain background have selective degeneration of inner hair cells while outer hair cells remain struct ...
... Dominant mutations of transmembrane channel-like gene 1 (TMC1) cause progressive sensorineural hearing loss in humans and Beethoven (Tmc1Bth/1) mice. Here we show that Tmc1Bth/1 mice on a C3HeB/FeJ strain background have selective degeneration of inner hair cells while outer hair cells remain struct ...
Genetic Control of Seed Shattering in Rice by the
... Previous studies of rice (Oryza sativa) have identified a few of the factors involved in seed shattering. SH4 is a member of the trihelix family of transcription factors and promotes hydrolyzing of AZ cells during the abscission process (Li et al., 2006; Lin et al., 2007). The cultivated rice allele ...
... Previous studies of rice (Oryza sativa) have identified a few of the factors involved in seed shattering. SH4 is a member of the trihelix family of transcription factors and promotes hydrolyzing of AZ cells during the abscission process (Li et al., 2006; Lin et al., 2007). The cultivated rice allele ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse