iTagPlot: an accurate computation and interactive drawing tool for
... iTagPlot uses an annotated list of genomic features in the BED format coupled with BED or BAM files of mapped reads to generate a tag density plot of the given feature with flanking upstream and downstream regions, the length of which is predetermined by the user (Fig. 1). Because the length of upst ...
... iTagPlot uses an annotated list of genomic features in the BED format coupled with BED or BAM files of mapped reads to generate a tag density plot of the given feature with flanking upstream and downstream regions, the length of which is predetermined by the user (Fig. 1). Because the length of upst ...
Genetic Algorithms
... 2. Females created for each male with maximum hamming distance 3. Select individuals to put into mating pool by either: Using a separate selection method for each sex Or, lumping them together and using one selection method over all of them 4. Mate each individual in the mating pool twice 5. If ther ...
... 2. Females created for each male with maximum hamming distance 3. Select individuals to put into mating pool by either: Using a separate selection method for each sex Or, lumping them together and using one selection method over all of them 4. Mate each individual in the mating pool twice 5. If ther ...
Discovery and identification of a novel double
... otherwise, the plant is male fertile if the nuclear gene is rr. Thus, plant is sterile only when mitochondria carry the MS gene while the cytoplasm gene is rr. The origin of 681A cytoplasm might be from a Japanese variety Chikuzen. Both the cytoplasm and nuclear of Xiangyou 13 are fertile. However, ...
... otherwise, the plant is male fertile if the nuclear gene is rr. Thus, plant is sterile only when mitochondria carry the MS gene while the cytoplasm gene is rr. The origin of 681A cytoplasm might be from a Japanese variety Chikuzen. Both the cytoplasm and nuclear of Xiangyou 13 are fertile. However, ...
Sex chromosomes and gender
... Male-specific pressures on the Y chromosome caused a region that was spatially linked to Sry to diverge from the X chromosome, leading to a loss of homology and recombination of those portions of the two chromosomes. The loss of recombination was important because it led to progressive degeneration ...
... Male-specific pressures on the Y chromosome caused a region that was spatially linked to Sry to diverge from the X chromosome, leading to a loss of homology and recombination of those portions of the two chromosomes. The loss of recombination was important because it led to progressive degeneration ...
Articles - American Scientist
... visible plaques. An additional explanation for the elusiveness of the largest viruses is that many infect protists, Figure 1. Giant viruses, which some call giruses in acknowledgment of their many unique features, comprise an ancient line that has been hidden in plain sight. Ironically, their gigant ...
... visible plaques. An additional explanation for the elusiveness of the largest viruses is that many infect protists, Figure 1. Giant viruses, which some call giruses in acknowledgment of their many unique features, comprise an ancient line that has been hidden in plain sight. Ironically, their gigant ...
A dominant mutation in the gene for the Nag
... (White, 1968). The nagCl protein is apparently insensitive to this inducer and can bind to the nag operators and repress in the presence of high levels of GlcNAc &phosphate present in the nagA strains. The insensitivity of the mutant repressor to GlcNAc 6phosphate was confirmed by an in vitro test ( ...
... (White, 1968). The nagCl protein is apparently insensitive to this inducer and can bind to the nag operators and repress in the presence of high levels of GlcNAc &phosphate present in the nagA strains. The insensitivity of the mutant repressor to GlcNAc 6phosphate was confirmed by an in vitro test ( ...
Recessive mutations
... Mutation at the Cellular Level • Somatic Mutation – arises in body cells that will not give rise to gametes (not passed to offspring) – can lead to mutant cell population – mutation of proto-oncogenes leads to cancer ...
... Mutation at the Cellular Level • Somatic Mutation – arises in body cells that will not give rise to gametes (not passed to offspring) – can lead to mutant cell population – mutation of proto-oncogenes leads to cancer ...
The Genetics of Microcephaly
... why males are more liable to be affected by certain diseases or traits such as colour blindness that are caused by faults within genes located on their solitary X chromosome. Different Types of Genetic Microcephaly Aside from microcephaly caused by major chromosome abnormalities such as Down's syndr ...
... why males are more liable to be affected by certain diseases or traits such as colour blindness that are caused by faults within genes located on their solitary X chromosome. Different Types of Genetic Microcephaly Aside from microcephaly caused by major chromosome abnormalities such as Down's syndr ...
How does the cell regulate arsenate respiration and
... b. Induction was determined by normalizing the expression value for arrA or arsC to no As conditions. Saltikov et al. J. Bacteriology 2005. 187 (21): 7390-7396 ...
... b. Induction was determined by normalizing the expression value for arrA or arsC to no As conditions. Saltikov et al. J. Bacteriology 2005. 187 (21): 7390-7396 ...
Transcription regulation of the Escherichia coli pcnB gene coding for
... There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly produced in response to variety of physico-chemical and nutritional stresses ( ...
... There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly produced in response to variety of physico-chemical and nutritional stresses ( ...
A comprehensive computational model of facilitated diffusion in
... questions consists of building a computational tool able to simulate the relevant molecules in a cell and the entire DNA sequence. This type of approach can address several questions, e.g. how crowding can influence the search process at genome-wide level, in a dynamical context (Chu et al., 2009) a ...
... questions consists of building a computational tool able to simulate the relevant molecules in a cell and the entire DNA sequence. This type of approach can address several questions, e.g. how crowding can influence the search process at genome-wide level, in a dynamical context (Chu et al., 2009) a ...
Inflorescence Meristem Identity in Rice Is Specified
... (Abe et al., 2005; Wigge et al., 2005). The FT protein is produced in leaves and then transported to the SAM, where it interacts with FLOWERING LOCUS D (FD). In the SAM, the SOC1 and FTFD complex promote expression of several downstream genes, including LEAFY, APETALA1 (AP1), and FRUITFULL (FUL), wh ...
... (Abe et al., 2005; Wigge et al., 2005). The FT protein is produced in leaves and then transported to the SAM, where it interacts with FLOWERING LOCUS D (FD). In the SAM, the SOC1 and FTFD complex promote expression of several downstream genes, including LEAFY, APETALA1 (AP1), and FRUITFULL (FUL), wh ...
extensions
... version of a gene in wild populations (ie, the “normal” version of a gene) – Wild-type proteins function normally – They promote the reproductive success of the organism • In large populations, there may be more than one common allele that can be considered wild-type – this is known as genetic polym ...
... version of a gene in wild populations (ie, the “normal” version of a gene) – Wild-type proteins function normally – They promote the reproductive success of the organism • In large populations, there may be more than one common allele that can be considered wild-type – this is known as genetic polym ...
extensions
... • Example: ABO blood type genes in humans – The enzyme glycosyl transferase adds sugars to the carbohydrate tree on the surface of red blood cells – Antibodies can distinguish between cells with different sugars added (between the different antigens) ...
... • Example: ABO blood type genes in humans – The enzyme glycosyl transferase adds sugars to the carbohydrate tree on the surface of red blood cells – Antibodies can distinguish between cells with different sugars added (between the different antigens) ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Isolation of genes in childhood itself can prevent its transmission to the future generations. ...
... Isolation of genes in childhood itself can prevent its transmission to the future generations. ...
Does premature aging of the mtDNA mutator mouse prove that
... and the types of mutations (e.g. large-scale deletions vs. point mutations, or proofreading errors vs. errors at chemically modified nucleotides), and thus the age- and tissue-specificity of mutation accumulation, are probably different from those in the mutator mouse. In accord with this, the mutat ...
... and the types of mutations (e.g. large-scale deletions vs. point mutations, or proofreading errors vs. errors at chemically modified nucleotides), and thus the age- and tissue-specificity of mutation accumulation, are probably different from those in the mutator mouse. In accord with this, the mutat ...
ELMER: An R/Bioconductor Tool Inferring Regulatory Element
... arbitrarily as an input to the get.diff.meth function in the ELMER, and should be tuned based on sample sizes in individual studies. The one tailed t-test was used to rule out the null hypothesis: µexperiment ≥ µcontrol, where µexperiment is the mean methylation within the lowest experiment quintile ...
... arbitrarily as an input to the get.diff.meth function in the ELMER, and should be tuned based on sample sizes in individual studies. The one tailed t-test was used to rule out the null hypothesis: µexperiment ≥ µcontrol, where µexperiment is the mean methylation within the lowest experiment quintile ...
Analyses of human–chimpanzee orthologous gene
... GenAge’s 242 protein-coding genes, 211 could be correctly analyzed. Similarly, of GenAge’s 242 protein-coding genes, we obtained 169 human–rhesus, 216 human–mouse, and 205 human–rat gene pairs that could be correctly analyzed. Therefore, genes of potential interest may have been left out of our anal ...
... GenAge’s 242 protein-coding genes, 211 could be correctly analyzed. Similarly, of GenAge’s 242 protein-coding genes, we obtained 169 human–rhesus, 216 human–mouse, and 205 human–rat gene pairs that could be correctly analyzed. Therefore, genes of potential interest may have been left out of our anal ...
Pierce Genetics: A Conceptual Approach 3e
... ALTER CHROMOSOME STRUCTURE • Inversions (depending on the involvement of ...
... ALTER CHROMOSOME STRUCTURE • Inversions (depending on the involvement of ...
Fungal cell wall chitinases and glucanases
... known to have roles during morphogenesis but no biochemical function had been identified for these proteins until Mouyna et al. (2000a) demonstrated that recombinant Gas1p, Phr1p and Phr2p each has 1,3-b-glucanosyltransferase activity similar to that of A. fumigatus Gel1p. Furthermore, expression of ...
... known to have roles during morphogenesis but no biochemical function had been identified for these proteins until Mouyna et al. (2000a) demonstrated that recombinant Gas1p, Phr1p and Phr2p each has 1,3-b-glucanosyltransferase activity similar to that of A. fumigatus Gel1p. Furthermore, expression of ...
ARVO 2004 poster file
... vesicle-mediated transport /// regulation of JNK cascade regulation of transcription, DNA-dependent; apoptosis ----regulation of transcription, DNA-dependent fatty acid biosynthesis DNA replication /// DNA repair /// protein biosynthesis ----signal transduction --apoptosis;activation of NF-kappaB-in ...
... vesicle-mediated transport /// regulation of JNK cascade regulation of transcription, DNA-dependent; apoptosis ----regulation of transcription, DNA-dependent fatty acid biosynthesis DNA replication /// DNA repair /// protein biosynthesis ----signal transduction --apoptosis;activation of NF-kappaB-in ...
Cluster analysis
... A reliable and precise classification of tumours is essential for successful diagnosis and treatment of cancer. Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diag ...
... A reliable and precise classification of tumours is essential for successful diagnosis and treatment of cancer. Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diag ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse