Liu - Blumberg Lab
... cellular context • Identified variation in transcriptional networks across cell lines under the same conditions • Generated general prediction factors for lncRNA hits using machine learning ...
... cellular context • Identified variation in transcriptional networks across cell lines under the same conditions • Generated general prediction factors for lncRNA hits using machine learning ...
Stabilizing synthetic data in the DNA of living organisms
... sequences. Thus, it is extremely rare for the occurrence of both sources of errors at the same position within the multiple data-encoded regions. When the letters at a same position of multiple alignments of decoded data sequences are different, it is likely that the minority letters have arisen fro ...
... sequences. Thus, it is extremely rare for the occurrence of both sources of errors at the same position within the multiple data-encoded regions. When the letters at a same position of multiple alignments of decoded data sequences are different, it is likely that the minority letters have arisen fro ...
Resources: - Real Science
... Pupils will not know some of the words used in the text. Meanings are given below, followed by an exercise in matching words and meanings. Teachers may choose to provide some or all of the meanings to help pupils read and understand the story. An approach that leads to better learning is to ask pupi ...
... Pupils will not know some of the words used in the text. Meanings are given below, followed by an exercise in matching words and meanings. Teachers may choose to provide some or all of the meanings to help pupils read and understand the story. An approach that leads to better learning is to ask pupi ...
v2 PEBiosystems News 2 01/00
... to undertake studies of growing complexity and scope. The assays provide a more efficient workflow by streamlining the experimental design process and simplifying analysis. The savings in precious resources and time will free researchers and bioinformatics experts for other work. As a result, we exp ...
... to undertake studies of growing complexity and scope. The assays provide a more efficient workflow by streamlining the experimental design process and simplifying analysis. The savings in precious resources and time will free researchers and bioinformatics experts for other work. As a result, we exp ...
BOX 39.2 MOLECULAR MECHANISMS OF CIRCADIAN
... Virtually nothing was known about the genetic and molecularmechanisms controlling circadian rhythms until the late 1960s, when Seymour Benzer and his graduate student, Ron Konopka, identified the first mutations affecting circadian behavior. Most scientists at the timewere skeptical that individual ...
... Virtually nothing was known about the genetic and molecularmechanisms controlling circadian rhythms until the late 1960s, when Seymour Benzer and his graduate student, Ron Konopka, identified the first mutations affecting circadian behavior. Most scientists at the timewere skeptical that individual ...
Experiment 3
... naturally occur in one of 107 cells. For a strepR mutation to occur, a mutation will occur naturally in one of 109 cells. To get any one of these mutations one must need to start out with a lot of cells to have chance isolating these mutants. To increase the frequency of mutants, we introduce the ce ...
... naturally occur in one of 107 cells. For a strepR mutation to occur, a mutation will occur naturally in one of 109 cells. To get any one of these mutations one must need to start out with a lot of cells to have chance isolating these mutants. To increase the frequency of mutants, we introduce the ce ...
Comparative analysis of mono(2-ethylhexyl)phthalate (MEHP) and
... Fat cells proliferate in childhood, but not in adulthood; fat cell numbers are set and generally stay constant through adult life (Spalding et al. 2008). Therefore, for both fat cell biology and obesity development, the influences of phthalates on preadipocytes and mature adipocytes could be fundame ...
... Fat cells proliferate in childhood, but not in adulthood; fat cell numbers are set and generally stay constant through adult life (Spalding et al. 2008). Therefore, for both fat cell biology and obesity development, the influences of phthalates on preadipocytes and mature adipocytes could be fundame ...
Reciprocal products of chromosomal translocations in human
... non-Hodgkin lymphomas arising from GC B cells, as a result of two distinct mechanisms: (1) chromosomal translocations leading to the substitution of the gene promoter region by sequences of a partner gene [8]; and (2) mutations affecting its 5′ noncoding regulatory region [9]. In addition to proto-o ...
... non-Hodgkin lymphomas arising from GC B cells, as a result of two distinct mechanisms: (1) chromosomal translocations leading to the substitution of the gene promoter region by sequences of a partner gene [8]; and (2) mutations affecting its 5′ noncoding regulatory region [9]. In addition to proto-o ...
Genetic and Molecular Diagnostics – Next Generation Sequencing
... the laboratory is located in a geographical area that has adopted MolDX guidelines. a. For Medicare jurisdictions which HAVE adopted MolDX Program guidelines: i. The MolDX Program has determined certain gene tests do not meet Medicare’s medical necessary requirements, and that the inclusion of these ...
... the laboratory is located in a geographical area that has adopted MolDX guidelines. a. For Medicare jurisdictions which HAVE adopted MolDX Program guidelines: i. The MolDX Program has determined certain gene tests do not meet Medicare’s medical necessary requirements, and that the inclusion of these ...
genetic testing
... also been linked with increasing risk of specific types of cancer: § breast cancer – most cases of breast cancer are sporadic, and the genetic factors involved have yet to be identified. Mutations in the BRCA 1 and 2 genes are linked with increased risk of the rarer, familial form of the disease. § ...
... also been linked with increasing risk of specific types of cancer: § breast cancer – most cases of breast cancer are sporadic, and the genetic factors involved have yet to be identified. Mutations in the BRCA 1 and 2 genes are linked with increased risk of the rarer, familial form of the disease. § ...
Changes in DNA-binding activity of transcription factors in the
... This study showed that nuclear proteins from the bovine mammary gland form two NFI-specific DNA-protein complexes (Photo 2A). Changes of slowly migrating complex 1 show some similarity to NFI DNA-protein complex in mice. This DNAprotein complex was abundant in virgin and pregnant heifers but sharply ...
... This study showed that nuclear proteins from the bovine mammary gland form two NFI-specific DNA-protein complexes (Photo 2A). Changes of slowly migrating complex 1 show some similarity to NFI DNA-protein complex in mice. This DNAprotein complex was abundant in virgin and pregnant heifers but sharply ...
AP Biology Essay Questions
... 15. Energy transfer occurs in all cellular activities. For 3 of the following 5 processes involving energy transfer, explain how each functions in the cell and give an example. Explain how ATP is involved in each example you choose. ...
... 15. Energy transfer occurs in all cellular activities. For 3 of the following 5 processes involving energy transfer, explain how each functions in the cell and give an example. Explain how ATP is involved in each example you choose. ...
It`s in the Genes - CR Alpacas, Inc.
... are transmitted as a recessive trait. This is because greys with nowhite markings almost never produce grey cria themselves unless bred to grey. Returning to the risks of using white spot alleles in a breeding program. BEWs themselves should not produce more BEWs unless they are bred to BEW or other ...
... are transmitted as a recessive trait. This is because greys with nowhite markings almost never produce grey cria themselves unless bred to grey. Returning to the risks of using white spot alleles in a breeding program. BEWs themselves should not produce more BEWs unless they are bred to BEW or other ...
Brevifollis gellanilyticus gen. nov., sp. nov., a gellan-gum
... Gen III MicroPlate during 1 week of incubation at 30 uC. This period of time was necessary for the positive control to become clearly positive. Growth on saccharides, catalase activity, oxidase activity and the temperature range for growth were determined as previously described (Otsuka et al., 2013 ...
... Gen III MicroPlate during 1 week of incubation at 30 uC. This period of time was necessary for the positive control to become clearly positive. Growth on saccharides, catalase activity, oxidase activity and the temperature range for growth were determined as previously described (Otsuka et al., 2013 ...
Handouts BIO301-Essentials of Genetics Virtual University of Pakistan
... Alleles for different traits are distributed to sex cells independently of one another. Traits are transmitted to offspring independently of one another. Example: Dihybrid cross, true-breeding plants for two traits. For example, a plant that had green pod color and yellow seed color was cross-pollin ...
... Alleles for different traits are distributed to sex cells independently of one another. Traits are transmitted to offspring independently of one another. Example: Dihybrid cross, true-breeding plants for two traits. For example, a plant that had green pod color and yellow seed color was cross-pollin ...
Intercellular signals downstream of endothelin
... midline streak of white pigmentation was observed on the ventral surface of some sl/+ animals. In contrast, sl/sl mice had primarily white coats except around the base of their ears and/or tails where a small patch of black pigmentation usually appeared. Crosses between sl/+ parents yielded average ...
... midline streak of white pigmentation was observed on the ventral surface of some sl/+ animals. In contrast, sl/sl mice had primarily white coats except around the base of their ears and/or tails where a small patch of black pigmentation usually appeared. Crosses between sl/+ parents yielded average ...
Networks in leaf development
... the leaf primordium and repress FIL expression on the adaxial side of the leaf primordium. This demonstrates that FIL is actively excluded from the adaxial domain [32]. The role of YABBY genes in abaxial specification is not clear, however, because loss-of-function mutants do not have obvious dorsov ...
... the leaf primordium and repress FIL expression on the adaxial side of the leaf primordium. This demonstrates that FIL is actively excluded from the adaxial domain [32]. The role of YABBY genes in abaxial specification is not clear, however, because loss-of-function mutants do not have obvious dorsov ...
A long-term demasculinization of X
... noncoding RNAs from novel exons of protein-coding genes or nondegraded intronic transcripts (we provide the chromosomal distribution of intronic ncRNAs in Supplemental Fig. S2). In all three comparisons performed using male/female adult transcriptome profiles derived from either whole body or reprod ...
... noncoding RNAs from novel exons of protein-coding genes or nondegraded intronic transcripts (we provide the chromosomal distribution of intronic ncRNAs in Supplemental Fig. S2). In all three comparisons performed using male/female adult transcriptome profiles derived from either whole body or reprod ...
Glossary - Red Angus Association of America
... information unique to an individual. A DNA molecule is composed of two strands of nucleotides bound to one another by chemical bonds between each complementary (A – T and G – C) base pair. The molecule has the appearance of a twisted ladder. The sequence of bases within DNA molecules determine amino ...
... information unique to an individual. A DNA molecule is composed of two strands of nucleotides bound to one another by chemical bonds between each complementary (A – T and G – C) base pair. The molecule has the appearance of a twisted ladder. The sequence of bases within DNA molecules determine amino ...
Dragon Genetics
... Preparations of Popsicle Stick Chromosomes Each popsicle stick represents a pair of homologous chromosomes, with the alleles of one of the homologous chromosomes on one side of the popsicle stick and the alleles of the other homologous chromosome on the other side of the popsicle stick. The appropri ...
... Preparations of Popsicle Stick Chromosomes Each popsicle stick represents a pair of homologous chromosomes, with the alleles of one of the homologous chromosomes on one side of the popsicle stick and the alleles of the other homologous chromosome on the other side of the popsicle stick. The appropri ...
A genetic linkage map for watermelon based on
... watermelon cultivars. Several gene mutants that affect a few of these morphological characteristics have been identified (Rhodes and Dane, 1999). High-density genetic linkage maps are useful for positioning and tagging genes of interest to facilitate marker-assisted breeding in an increasing number ...
... watermelon cultivars. Several gene mutants that affect a few of these morphological characteristics have been identified (Rhodes and Dane, 1999). High-density genetic linkage maps are useful for positioning and tagging genes of interest to facilitate marker-assisted breeding in an increasing number ...
PDF - The Journal of General Physiology
... Intact Phage.--The intact phage was mixed with the Ilford G-5 emulsion on three different dates corresponding to 0, 40, and 50 per cent of the incorporated p3~ decayed. A total of nine different emulsions was counted; the average star size extended from 7.4 to 15.4 rays per star. The average of thes ...
... Intact Phage.--The intact phage was mixed with the Ilford G-5 emulsion on three different dates corresponding to 0, 40, and 50 per cent of the incorporated p3~ decayed. A total of nine different emulsions was counted; the average star size extended from 7.4 to 15.4 rays per star. The average of thes ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse