
Methods for detecting positive selection and examples among fungi
... rate. The Bayesian method can be employed to infer which sites in the alignment are under positive selection. This method is used to compute the posterior probability that each site belongs to a particular v class. A site with a posterior probability (0.95) of belonging to the class of sites with v ...
... rate. The Bayesian method can be employed to infer which sites in the alignment are under positive selection. This method is used to compute the posterior probability that each site belongs to a particular v class. A site with a posterior probability (0.95) of belonging to the class of sites with v ...
Fact Sheet 52|HAEMOPHILIA WHAT IS HAEMOPHILIA
... Our body is made up of millions of cells, and in each cell there are instructions, called genes, that make all the necessary structural components and chemicals for the body to function. These genes are packaged onto little long strands known as chromosomes. We all have 46 chromosomes arranged into ...
... Our body is made up of millions of cells, and in each cell there are instructions, called genes, that make all the necessary structural components and chemicals for the body to function. These genes are packaged onto little long strands known as chromosomes. We all have 46 chromosomes arranged into ...
Embryonic fat-cell lineage in Drosophila melanogaster
... (Fig. 1C). Holes within the ribbon are formed by the intrusion of various organs. In a dorsal view, the main portion of the fat body appeared as a bilateral band extending from the gonads to the thoracic region (Fig. 1B). The developing dorsal fat body was visible as it extended medially from the la ...
... (Fig. 1C). Holes within the ribbon are formed by the intrusion of various organs. In a dorsal view, the main portion of the fat body appeared as a bilateral band extending from the gonads to the thoracic region (Fig. 1B). The developing dorsal fat body was visible as it extended medially from the la ...
Dominant and Recessive Genes
... dominant gene from on parent unites with the gamete carrying the dominant gene from the other parent, the offspring produced are homozygous dominant. If the gamete carrying the dominant gene from one parent unites with the gamete carrying the recessive gene form the other parent, the offspring are h ...
... dominant gene from on parent unites with the gamete carrying the dominant gene from the other parent, the offspring produced are homozygous dominant. If the gamete carrying the dominant gene from one parent unites with the gamete carrying the recessive gene form the other parent, the offspring are h ...
A Fine Physical Map of Arabidopsis thaliana Chromosome 5
... similar to the tandemly repeated 180-bp sequence contained in plasmid pALl. 25 This repeated DNA sequence is present in arrays of over 50 kb, has been shown to locate in the heterochromatin moiety surrounding the centromere26'27 and to hybridize equally to both sides of the centromere on all five ch ...
... similar to the tandemly repeated 180-bp sequence contained in plasmid pALl. 25 This repeated DNA sequence is present in arrays of over 50 kb, has been shown to locate in the heterochromatin moiety surrounding the centromere26'27 and to hybridize equally to both sides of the centromere on all five ch ...
manuscript pdf
... carrying two loci, was used in subsequent crosses. Significantly, the Tdef floral phenotype is similar to that of Arabidopsis floral morphogenesis mutant 10 (FlolO, also known as Superman) mutants or transgenic plants in which the AP3 gene is under the control of the cauliflower mosaic virus 35S pro ...
... carrying two loci, was used in subsequent crosses. Significantly, the Tdef floral phenotype is similar to that of Arabidopsis floral morphogenesis mutant 10 (FlolO, also known as Superman) mutants or transgenic plants in which the AP3 gene is under the control of the cauliflower mosaic virus 35S pro ...
developing corn hybrids with new traits
... maximize the performance of the genetics being grown by farmers. The introduction of hybrids in the 1930s coincided with the introduction of modern fertility and management practices (Russell, 1991). Since the introduction of hybrids, corn yields have increased from an average of about 30 bushels pe ...
... maximize the performance of the genetics being grown by farmers. The introduction of hybrids in the 1930s coincided with the introduction of modern fertility and management practices (Russell, 1991). Since the introduction of hybrids, corn yields have increased from an average of about 30 bushels pe ...
What is meant by the term monogenic? What`s probability got to do
... 1 - the event is certain to occur 0 - the event is certain not to happen In all other cases the chance that a particular event will occur increases as the probability approaches 1. ...
... 1 - the event is certain to occur 0 - the event is certain not to happen In all other cases the chance that a particular event will occur increases as the probability approaches 1. ...
Repetitive complete hydatidiform mole can be biparental in origin
... as in a normal pregnancy. The rarity of these cases makes it difficult to estimate their true frequency. However, a recent study of two families in which several sisters had one or more CHM, found that all CHM examined were biparental in origin (Moglabey et al., 1999) suggesting that familial repeti ...
... as in a normal pregnancy. The rarity of these cases makes it difficult to estimate their true frequency. However, a recent study of two families in which several sisters had one or more CHM, found that all CHM examined were biparental in origin (Moglabey et al., 1999) suggesting that familial repeti ...
Expression of floricaula in single cell layers of
... (Fig. 2). This gave a 9.0 kb band for flo-613 and a 5.5 kb band for wild-type plants that lack the 3.5 kb Tam3 element (Fig. 2A, left two lanes). Most of the chimeras had a 9.0 kb band, showing that they carried Tam3 in the flo gene. In addition, all chimeras had a 5.5 kb band of varying intensity, ...
... (Fig. 2). This gave a 9.0 kb band for flo-613 and a 5.5 kb band for wild-type plants that lack the 3.5 kb Tam3 element (Fig. 2A, left two lanes). Most of the chimeras had a 9.0 kb band, showing that they carried Tam3 in the flo gene. In addition, all chimeras had a 5.5 kb band of varying intensity, ...
Nixon Evidence
... to mitochondrial ferredoxins and the hydrogenosomal ferredoxin of Trichomonas vaginalis (another luminal protist). However, phylogenetic trees were star shaped, with weak bootstrap support, so we were unable to confirm or rule out the endosymbiotic origin of the giardia [2Fe-2S]ferredoxin gene. Puta ...
... to mitochondrial ferredoxins and the hydrogenosomal ferredoxin of Trichomonas vaginalis (another luminal protist). However, phylogenetic trees were star shaped, with weak bootstrap support, so we were unable to confirm or rule out the endosymbiotic origin of the giardia [2Fe-2S]ferredoxin gene. Puta ...
Evolution of Coloration Patterns
... D. melanogaster (reviewed in Wittkopp et al. 2003a). Pigmentation in mice is also a vast field of research. There are more than 127 loci in mice affecting coloration (Bennett & Lamoreux 2003). Mammalian melanocytes, or pigment cells, are derived from the neural crest and migrate to various areas of t ...
... D. melanogaster (reviewed in Wittkopp et al. 2003a). Pigmentation in mice is also a vast field of research. There are more than 127 loci in mice affecting coloration (Bennett & Lamoreux 2003). Mammalian melanocytes, or pigment cells, are derived from the neural crest and migrate to various areas of t ...
Are 100 enough? Inferring acanthomorph teleost phylogeny using
... taxonomic sampling than what was used for the original UCE design, increasing capture efficiency for a wider taxonomic range relative to those markers. This facilitates the capture of homologous loci that are useful for both old and more recent divergences, a property shared with UCEs [22, 27]. One ...
... taxonomic sampling than what was used for the original UCE design, increasing capture efficiency for a wider taxonomic range relative to those markers. This facilitates the capture of homologous loci that are useful for both old and more recent divergences, a property shared with UCEs [22, 27]. One ...
- Ex Student Archive
... also refer to several other aspects. The wholesomeness in meat quality is an important aspect which may refer to the products´ nutritional value and to microbial and/or chemical food safety. High meat quality may also refer to a carcass with a favourable conformation and an optimal ratio of fat and ...
... also refer to several other aspects. The wholesomeness in meat quality is an important aspect which may refer to the products´ nutritional value and to microbial and/or chemical food safety. High meat quality may also refer to a carcass with a favourable conformation and an optimal ratio of fat and ...
Edgetic perturbation models of human inherited disorders, Mol Syst
... characterization in the literature. Given these criteria, we could apply our allele-profiling platform to one autosomal recessive disease protein (CBS), and to three autosomal dominant disease proteins with likely dominant-negative (ACTG1), abnormal activation (CDK4), or haploinsufficiency (PRKAR1A) ...
... characterization in the literature. Given these criteria, we could apply our allele-profiling platform to one autosomal recessive disease protein (CBS), and to three autosomal dominant disease proteins with likely dominant-negative (ACTG1), abnormal activation (CDK4), or haploinsufficiency (PRKAR1A) ...
Guppies – Quang Anh
... during the third simulation, when the predation level is low. During the third simulation, the gene frequency of the brightest guppies was the highest, at 0.78, and so, it proves that those are the ones seen as the most attractive by the female guppies. And although the predation, natural force, pla ...
... during the third simulation, when the predation level is low. During the third simulation, the gene frequency of the brightest guppies was the highest, at 0.78, and so, it proves that those are the ones seen as the most attractive by the female guppies. And although the predation, natural force, pla ...
genomebiology.com
... found within the coding sequence (Additional file 3). Exonizations in non-mammals frequently disrupted the open reading frame of a protein, similar to results previously reported for human and mouse. In G. gallus, D. rerio and C. intestinalis only 38 to 50% of the exonized TEs have lengths divisible ...
... found within the coding sequence (Additional file 3). Exonizations in non-mammals frequently disrupted the open reading frame of a protein, similar to results previously reported for human and mouse. In G. gallus, D. rerio and C. intestinalis only 38 to 50% of the exonized TEs have lengths divisible ...
Similarities and differences of gene expression in yeast stress
... living organisms are complex and involve several types of control, monitoring and activation/de-activation modules. These are only partially understood and the subject of continuous efforts to better elucidate. Model systems, such as Saccharomyces cerevisiae, play an important role in this study. So ...
... living organisms are complex and involve several types of control, monitoring and activation/de-activation modules. These are only partially understood and the subject of continuous efforts to better elucidate. Model systems, such as Saccharomyces cerevisiae, play an important role in this study. So ...
Allelic Deletions on Chromosome 11q13 in Multiple Endocrine
... The reactions were performedin a Perkin-ElmerCorp. thermal cycler as nal microgastrinomas from a female FMEN1 patient 2 (Tables 2 and 5) were follows: denaturation at 94°Cfor 5 rain, followed by 35 cycles of annealing for studied for X-chromosome inactivation to assess clonality (Fig. 4). Extracted ...
... The reactions were performedin a Perkin-ElmerCorp. thermal cycler as nal microgastrinomas from a female FMEN1 patient 2 (Tables 2 and 5) were follows: denaturation at 94°Cfor 5 rain, followed by 35 cycles of annealing for studied for X-chromosome inactivation to assess clonality (Fig. 4). Extracted ...
Genetic data indicate that proteins containing the GGDEF domain
... pYhcK £occulated heavily (Fig. 3B,C). Strong £uorescence was observed in and around these aggregates in the microscope after staining with Calco£uor (data not shown). Plasmid pYhcK caused the strongest aggregation in the liquid culture (Fig. 3C). These results support the data presented by Amikam an ...
... pYhcK £occulated heavily (Fig. 3B,C). Strong £uorescence was observed in and around these aggregates in the microscope after staining with Calco£uor (data not shown). Plasmid pYhcK caused the strongest aggregation in the liquid culture (Fig. 3C). These results support the data presented by Amikam an ...
Lessons from Functional Analysis of Genome
... However, the SNPs can mark a region that is very important in cancer; they may for instance identify a region containing a causative mutation that is more rare and has higher penetrance. High-throughput whole-genome sequencing techniques have already identified one such SNP in 8q24, rs188140481, that ...
... However, the SNPs can mark a region that is very important in cancer; they may for instance identify a region containing a causative mutation that is more rare and has higher penetrance. High-throughput whole-genome sequencing techniques have already identified one such SNP in 8q24, rs188140481, that ...
Meiosis - DiBiasioScience
... Meiosis II Second division of meiosis: Gamete formation • Prophase 2: DNA does not replicate. • Metaphase 2: Chromosomes align at the equatorial plate. • Anaphase 2: Centromeres divide and sister chromatids migrate separately to each pole. • Telophase 2: Cell division is complete. Four haploid daug ...
... Meiosis II Second division of meiosis: Gamete formation • Prophase 2: DNA does not replicate. • Metaphase 2: Chromosomes align at the equatorial plate. • Anaphase 2: Centromeres divide and sister chromatids migrate separately to each pole. • Telophase 2: Cell division is complete. Four haploid daug ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse