Inhibition of protein synthesis by streptogramins and related
... stages of protein synthesis. The conformational change increases ribosomal affinity for type B streptogramins. Microbial resistance to the MLSB antibiotics is largely attributable to mutations of rRNA bases, producing conformational changes in the peptidyl transferase centre. This can result in resi ...
... stages of protein synthesis. The conformational change increases ribosomal affinity for type B streptogramins. Microbial resistance to the MLSB antibiotics is largely attributable to mutations of rRNA bases, producing conformational changes in the peptidyl transferase centre. This can result in resi ...
Problems from Strickberger`s Genetics
... 7-11. Down syndrome (mongolian idiocy; Chapter 21) occurs in humans when a particular chromosome (no. 21) is present in triplicate instead of in the usual diploid state; i.e., such individuals have 47 chromosomes instead of the normal 46. What proportion of offspring produced by an affected mother w ...
... 7-11. Down syndrome (mongolian idiocy; Chapter 21) occurs in humans when a particular chromosome (no. 21) is present in triplicate instead of in the usual diploid state; i.e., such individuals have 47 chromosomes instead of the normal 46. What proportion of offspring produced by an affected mother w ...
Multifractal analysis of DNA sequences using a novel chaos
... other dimension-like and entropy-like measures, inspired by the information-theoretical measures that are widely used in linguistics [31,32], the analysis of local singularities does not focus on a single exponent, but considers all the scaling behaviors within the sequence. Moreover, some of these ...
... other dimension-like and entropy-like measures, inspired by the information-theoretical measures that are widely used in linguistics [31,32], the analysis of local singularities does not focus on a single exponent, but considers all the scaling behaviors within the sequence. Moreover, some of these ...
Mapping quantitative trait loci and expressed sequence tags related
... 2001, Yang et al. 2002). However, the BPH resistance conferred by these major genes is not durable; for example, Bph1 and bph2 can be overcome by BPH biotypes 2 and 3 (Pathak and Heinrichs 1982, Panda and Khush 1995). In contrast, quantitative trait loci (QTLs) were found to confer more durable BPH ...
... 2001, Yang et al. 2002). However, the BPH resistance conferred by these major genes is not durable; for example, Bph1 and bph2 can be overcome by BPH biotypes 2 and 3 (Pathak and Heinrichs 1982, Panda and Khush 1995). In contrast, quantitative trait loci (QTLs) were found to confer more durable BPH ...
O4 M.A. Rouf Mian
... genetic sources of resistance to SA. Several research groups in the USA have recently identified SA resistant soybean germplasm (Mian et al. 2008). ...
... genetic sources of resistance to SA. Several research groups in the USA have recently identified SA resistant soybean germplasm (Mian et al. 2008). ...
Patterns of Segmental Duplication in the Human Genome
... dynamic programming for up to 5 kb outward from both ends of the alignment, while maintaining the requirement 90% sequence similarity during the extension process. Noting that some regions showed a higher density of duplication than others, we examined these regions for possible causes of duplicat ...
... dynamic programming for up to 5 kb outward from both ends of the alignment, while maintaining the requirement 90% sequence similarity during the extension process. Noting that some regions showed a higher density of duplication than others, we examined these regions for possible causes of duplicat ...
The Confluence of Philosophy And Biology: An Excavation of
... In view of the above paradigm shift in biological studies, many, ethical, epistemological, metaphysical challenges have been observed; thus, there is need for philosophical evaluations. It is within this frame of reasoning that the topic: “The confluence of philosophy and Biology: An excavation of ...
... In view of the above paradigm shift in biological studies, many, ethical, epistemological, metaphysical challenges have been observed; thus, there is need for philosophical evaluations. It is within this frame of reasoning that the topic: “The confluence of philosophy and Biology: An excavation of ...
The Novel Gene HOMOLOGOUS PAIRING
... required for homologous chromosome pairing and cytokinesis in male and female meiocytes of rice (Oryza sativa). The pair1 mutation, tagged by the endogenous retrotransposon Tos17, exhibited meiosis-specific defects and resulted in complete sterility in male and female gametes. The PAIR1 gene encodes ...
... required for homologous chromosome pairing and cytokinesis in male and female meiocytes of rice (Oryza sativa). The pair1 mutation, tagged by the endogenous retrotransposon Tos17, exhibited meiosis-specific defects and resulted in complete sterility in male and female gametes. The PAIR1 gene encodes ...
Chapter 1 Introduction
... chromosomes and their role in heredity. Conventional chromosome analysis using G-banding is widely used for clinical diagnostics and genomic research. However, over the past 30 years the development of new techniques with increasingly higher resolution has led to the new field of molecular cytogenet ...
... chromosomes and their role in heredity. Conventional chromosome analysis using G-banding is widely used for clinical diagnostics and genomic research. However, over the past 30 years the development of new techniques with increasingly higher resolution has led to the new field of molecular cytogenet ...
Quantitative trait loci and the study of plant domestication
... ‘domestication may have occurred more readily without requiring the fortuitous occurrence of multiple major mutations.’ While this may be true if adaptation under artificial selection depends solely on novel mutations, theory suggests that the opposite could occur if selection acts on standing geneti ...
... ‘domestication may have occurred more readily without requiring the fortuitous occurrence of multiple major mutations.’ While this may be true if adaptation under artificial selection depends solely on novel mutations, theory suggests that the opposite could occur if selection acts on standing geneti ...
Multiple Avirulence Loci and Allele-Specific Effector
... Articles can be viewed online without a subscription. www.plantcell.org/cgi/doi/10.1105/tpc.15.00171 2 Current ...
... Articles can be viewed online without a subscription. www.plantcell.org/cgi/doi/10.1105/tpc.15.00171 2 Current ...
Import of genetically modified carnation `Moonaqua`
... already been approved for commercial production within the EU. In the environmental risk assessment the probability of gene dispersal, weediness and potential risks to consumers due to incidental consumption has to be considered. The number of relevant issues is limited however, since this applicati ...
... already been approved for commercial production within the EU. In the environmental risk assessment the probability of gene dispersal, weediness and potential risks to consumers due to incidental consumption has to be considered. The number of relevant issues is limited however, since this applicati ...
Supplementary Table Legends
... with the widest range of expression used for unsupervised clustering of TCGA and CRPC samples. The average RPKM difference between CRPC and TCGA primary prostate cancers is ...
... with the widest range of expression used for unsupervised clustering of TCGA and CRPC samples. The average RPKM difference between CRPC and TCGA primary prostate cancers is ...
RNA Interference and Small Interfering RNAs
... it is desirable to prevent the gradual loss of siRNAs is indicated. RNAi in the injected animal or its offspring. This is possible by the introduction of transgenes composed ing at a considerable distance. In plants, grafting experiof inverted repeats which produce dsRNA hairpins after tranments[48, ...
... it is desirable to prevent the gradual loss of siRNAs is indicated. RNAi in the injected animal or its offspring. This is possible by the introduction of transgenes composed ing at a considerable distance. In plants, grafting experiof inverted repeats which produce dsRNA hairpins after tranments[48, ...
RecA maintains the integrity of chloroplast DNA molecules in
... nuclear genomes of many organisms, including plants (Lin et al., 2006). Repair and recombination of chloroplast DNA (cpDNA) in Chlamydomonas reinhardtii is suppressed when a dominant-negative version of E. coli RecA is targeted to chloroplasts (Cerutti et al., 1995). The prevalence of chloroplast-ta ...
... nuclear genomes of many organisms, including plants (Lin et al., 2006). Repair and recombination of chloroplast DNA (cpDNA) in Chlamydomonas reinhardtii is suppressed when a dominant-negative version of E. coli RecA is targeted to chloroplasts (Cerutti et al., 1995). The prevalence of chloroplast-ta ...
Downloaded - Journal of Medical Genetics
... pedigree presented with demineralisation. Thus, the entity in this family was microscopically similar to PDB (increased osteoclastic activity) but radiologically, clinically, and macroscopically different from it. On the other hand, pathological fractures, which are common in FEO, did not occur, eve ...
... pedigree presented with demineralisation. Thus, the entity in this family was microscopically similar to PDB (increased osteoclastic activity) but radiologically, clinically, and macroscopically different from it. On the other hand, pathological fractures, which are common in FEO, did not occur, eve ...
Detection and copy number estimation of the transgenic nucleotide
... The spread and cultivation of unapproved rice varieties by the farming community is also a major problem because such varieties have not been tested for their resistance against biotic (mainly insects) and abiotic stresses, and suitable agronomic practices cannot be adopted according to the growth p ...
... The spread and cultivation of unapproved rice varieties by the farming community is also a major problem because such varieties have not been tested for their resistance against biotic (mainly insects) and abiotic stresses, and suitable agronomic practices cannot be adopted according to the growth p ...
Sex Chromosomes
... • DRepA construct expressed a transcript that clusters to the X chromosome, indicating that RepA is not responsible for proper localization on Xi. Conclusion: - The RepA containing region is responsible for X inacivation. - Transcriptional silencing and chromosomal localization are functionally sepa ...
... • DRepA construct expressed a transcript that clusters to the X chromosome, indicating that RepA is not responsible for proper localization on Xi. Conclusion: - The RepA containing region is responsible for X inacivation. - Transcriptional silencing and chromosomal localization are functionally sepa ...
(ARG) as Compatible Networks of SNP Patterns
... JAUME BERTRANPETIT,2 and THE GENOGRAPHIC CONSORTIUM3 ...
... JAUME BERTRANPETIT,2 and THE GENOGRAPHIC CONSORTIUM3 ...
Familial expansile osteolysis in a large Spanish kindred resulting
... pedigree presented with demineralisation. Thus, the entity in this family was microscopically similar to PDB (increased osteoclastic activity) but radiologically, clinically, and macroscopically different from it. On the other hand, pathological fractures, which are common in FEO, did not occur, eve ...
... pedigree presented with demineralisation. Thus, the entity in this family was microscopically similar to PDB (increased osteoclastic activity) but radiologically, clinically, and macroscopically different from it. On the other hand, pathological fractures, which are common in FEO, did not occur, eve ...
Adventitious root formation in rice requires OsGNOM1 and
... The fibrous root system in cereals comprises primarily adventitious roots (ARs), which play important roles in nutrient and water uptake. Current knowledge regarding the molecular mechanism underlying AR development is still limited. We report here the isolation of four rice (Oryza sativa L.) mutant ...
... The fibrous root system in cereals comprises primarily adventitious roots (ARs), which play important roles in nutrient and water uptake. Current knowledge regarding the molecular mechanism underlying AR development is still limited. We report here the isolation of four rice (Oryza sativa L.) mutant ...
BLAST Tips - Boston University
... • Needleman, S.B. and Wunsch, C.D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol. 48(3):44353(1970). ...
... • Needleman, S.B. and Wunsch, C.D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol. 48(3):44353(1970). ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse