
(HPV) L1 gene DNA possibly bound to particulate aluminum
... or a pair of GP5/MY09 general consensus primers. Three primer pairs were chosen to perform the second PCR to amplify multiple nests of the 450 bp MY09/MY11 PCR products in an attempt to cover possible sequence variants of the genotype-specific L1 genes that are used for manufacturing of the quadrival ...
... or a pair of GP5/MY09 general consensus primers. Three primer pairs were chosen to perform the second PCR to amplify multiple nests of the 450 bp MY09/MY11 PCR products in an attempt to cover possible sequence variants of the genotype-specific L1 genes that are used for manufacturing of the quadrival ...
Student Exploration: Mouse Genetics (One Trait)
... Prior Knowledge Questions (Do these BEFORE using the Gizmo.) ...
... Prior Knowledge Questions (Do these BEFORE using the Gizmo.) ...
Dissecting plant meiosis using Arabidopsis thaliana mutants
... If a particular gene knockout cannot be identi®ed it is possible to generate one. Directed gene disruption by homologous recombination, which is widely used in yeast and mouse would, in theory, be the best approach, but, unfortunately, this is not yet a realistic option in plants (Mengiste and Paszk ...
... If a particular gene knockout cannot be identi®ed it is possible to generate one. Directed gene disruption by homologous recombination, which is widely used in yeast and mouse would, in theory, be the best approach, but, unfortunately, this is not yet a realistic option in plants (Mengiste and Paszk ...
M.Tevfik Dorak, BA (Hons), MD, Ph.D.
... suffice it to say that when we have identified a mutant gene by "cloning" it, we can often immediately deduce something about its protein product's structure and make a reasonable guess as to its function (see for example the cystic fibrosis story later on). Also, we are able to look for the mutatio ...
... suffice it to say that when we have identified a mutant gene by "cloning" it, we can often immediately deduce something about its protein product's structure and make a reasonable guess as to its function (see for example the cystic fibrosis story later on). Also, we are able to look for the mutatio ...
BIOUnit 2 - 5E With LEP- FINAL
... interesting to come back to this questionnaire after we have studied genetics and see how your new answers compare to those you made before our studies. At that time, you should be able to explain why each of the incorrect statements is not true. Below are 20 statements that relate to various geneti ...
... interesting to come back to this questionnaire after we have studied genetics and see how your new answers compare to those you made before our studies. At that time, you should be able to explain why each of the incorrect statements is not true. Below are 20 statements that relate to various geneti ...
Analysis of DNA transcription termination sequences of gene coding
... are vastly different. The length of this region ranged from 60 bp (Pseudomonas putida AF150670) to 225 bp (Pseudomonas corrugata AY910767). In case of Pseudomonas USM4-55, Pseudomonas nitroreducens and Pseudomonas pseudoalcaligenes the size of the intergenic region is the same (141 bp), and they are ...
... are vastly different. The length of this region ranged from 60 bp (Pseudomonas putida AF150670) to 225 bp (Pseudomonas corrugata AY910767). In case of Pseudomonas USM4-55, Pseudomonas nitroreducens and Pseudomonas pseudoalcaligenes the size of the intergenic region is the same (141 bp), and they are ...
Page 1 Heredity (1977), 39 (3), 373
... which does not include the Est-6 locus, or at least that the Est-6 locus is near the end of such a region. Rendel (1976) has shown that a region of the third chromosome that includes the Aph locus but not the Est-6 locus has an important influence on scutellar bristle number. Possession of the "muta ...
... which does not include the Est-6 locus, or at least that the Est-6 locus is near the end of such a region. Rendel (1976) has shown that a region of the third chromosome that includes the Aph locus but not the Est-6 locus has an important influence on scutellar bristle number. Possession of the "muta ...
The Biology of Aging
... Ashkenazi Jews • Large genetic component • Likely to be passed from generation to generation ...
... Ashkenazi Jews • Large genetic component • Likely to be passed from generation to generation ...
The Cyclin-Dependent Kinase Inhibitor KRP2
... correlation was found between the amount of transgenic KRP2 protein and the level of CDK inhibition. This observation points toward the presence of a KRP2-resistant fraction of CDK/cyclin complexes that cannot be inhibited by KRP2, even at high levels. As reported previously, strong KRP2OE lines had ...
... correlation was found between the amount of transgenic KRP2 protein and the level of CDK inhibition. This observation points toward the presence of a KRP2-resistant fraction of CDK/cyclin complexes that cannot be inhibited by KRP2, even at high levels. As reported previously, strong KRP2OE lines had ...
Independent Assortment of Genes
... With selfing, complete heterozygosity will yield a 9:3:3:1 phenotypic ratio. Homozygosity at one locus will yield a 3:1 phenotypic ratio, while homozygosity at both loci will yield only one phenotypic class. With a testcross, complete heterozygosity will yield a 1:1:1:1 phenotypic ratio. Homozygosit ...
... With selfing, complete heterozygosity will yield a 9:3:3:1 phenotypic ratio. Homozygosity at one locus will yield a 3:1 phenotypic ratio, while homozygosity at both loci will yield only one phenotypic class. With a testcross, complete heterozygosity will yield a 1:1:1:1 phenotypic ratio. Homozygosit ...
Evolution of colour vision in primates
... have been largely nocturnal species. For them, the ability to see in lowlight conditions was at a premium, rather than the ability to see in colour. The ancestors of modern mammals consequently lost colour vision at the time of the dinosaurs. Some primates, including humans of course, have re-evolve ...
... have been largely nocturnal species. For them, the ability to see in lowlight conditions was at a premium, rather than the ability to see in colour. The ancestors of modern mammals consequently lost colour vision at the time of the dinosaurs. Some primates, including humans of course, have re-evolve ...
Lecture #7
... Small branches within a clade indicate sexual reproduction is ongoing within that group of individuals ...
... Small branches within a clade indicate sexual reproduction is ongoing within that group of individuals ...
Regulatory Networks that Direct the Development of Specialized
... the existence of a fundamental cardiac toolbox has meant that model organisms have contributed significantly to our current understanding of heart specification and development. In particular, Drosophila has been a useful model for understanding the components of this toolbox and their genetic inter ...
... the existence of a fundamental cardiac toolbox has meant that model organisms have contributed significantly to our current understanding of heart specification and development. In particular, Drosophila has been a useful model for understanding the components of this toolbox and their genetic inter ...
Regulation of DNA Polymerase Exonucleolytic Proofreading Activity
... Amino acid substitutions that produce the antimutator phenotype were also identified in the polymerase active center, but the polymerase and exonuclease active centers are separated by a relatively great distance, about 30 Å (Wang et al. 1997). Proofreading requires that the primer strand be moved ...
... Amino acid substitutions that produce the antimutator phenotype were also identified in the polymerase active center, but the polymerase and exonuclease active centers are separated by a relatively great distance, about 30 Å (Wang et al. 1997). Proofreading requires that the primer strand be moved ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
association study of 37 genes suggests involvement of DDC
... Objectives. Neurotransmitter systems and neurotrophic factors can be considered strong candidates for autism spectrum disorder (ASD). The serotoninergic and dopaminergic systems are involved in neurotransmission, brain maturation and cortical organization, while neurotrophic factors (NTFs) participa ...
... Objectives. Neurotransmitter systems and neurotrophic factors can be considered strong candidates for autism spectrum disorder (ASD). The serotoninergic and dopaminergic systems are involved in neurotransmission, brain maturation and cortical organization, while neurotrophic factors (NTFs) participa ...
Mendel Genetics 2015
... • When Mendel crossed contrasting, truebreeding white and purple flowered pea plants, all of the F1 hybrids were purple • When Mendel crossed the F1 hybrids, many of the F2 plants had purple flowers, but some had white • Mendel discovered a ratio of about three to one, purple to white flowers, in th ...
... • When Mendel crossed contrasting, truebreeding white and purple flowered pea plants, all of the F1 hybrids were purple • When Mendel crossed the F1 hybrids, many of the F2 plants had purple flowers, but some had white • Mendel discovered a ratio of about three to one, purple to white flowers, in th ...
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... sequence (assigned GenBank accession no. AF495758) is most similar to published Blochmannia 16S rRNA sequences. Phylogenetic analysis of this and other 16S rRNA genes (data not shown) demonstrated that our samples are most closely related to the published C. pennsylvanicus endosymbiont 16S rRNA gen ...
... sequence (assigned GenBank accession no. AF495758) is most similar to published Blochmannia 16S rRNA sequences. Phylogenetic analysis of this and other 16S rRNA genes (data not shown) demonstrated that our samples are most closely related to the published C. pennsylvanicus endosymbiont 16S rRNA gen ...
Chapter 12
... The self-incompatibility alleles of many plant species are an example. The S locus in the cabbage family: 1. The "S locus" consists in reality of three loci. 2. There are multiple alleles of these genes, up to 50. 3. The proteins coded by these loci are located one in the membrane of the stigma cell ...
... The self-incompatibility alleles of many plant species are an example. The S locus in the cabbage family: 1. The "S locus" consists in reality of three loci. 2. There are multiple alleles of these genes, up to 50. 3. The proteins coded by these loci are located one in the membrane of the stigma cell ...
The photosynthetic apparatus of Prochlorococcus
... is numerically the most abundant, and it can grow deeper in the euphotic zone (Partensky et al., 1999a) presumably because Chl b2 allows it to efficiently harvest the low light intensities and blue wavelengths characteristic of deep water (Moore et al., 1995; Morel et al., 1993). Prochlorococcus iso ...
... is numerically the most abundant, and it can grow deeper in the euphotic zone (Partensky et al., 1999a) presumably because Chl b2 allows it to efficiently harvest the low light intensities and blue wavelengths characteristic of deep water (Moore et al., 1995; Morel et al., 1993). Prochlorococcus iso ...
DNA barcoding parasite organisms found in terrestrial
... because of its noninvasive nature and its capability for early detection of invasive species, non-native species which may offset the balance of a pre-established ecosystem where they are unfamiliar (Ficetola et. al. 2008). Catching invasive species early, through the discovery of the introduction o ...
... because of its noninvasive nature and its capability for early detection of invasive species, non-native species which may offset the balance of a pre-established ecosystem where they are unfamiliar (Ficetola et. al. 2008). Catching invasive species early, through the discovery of the introduction o ...
Identification and Analysis of Arabidopsis Expressed Sequence
... 2001). Analyses of the properties and functions of ncRNAs have indicated that they can act as gene regulators, as part of biotic and abiotic stress signals, or as part of RNA-protein complexes with various enzymatic and structural activities. A number of ncRNAs are processed in an mRNA-like manner; ...
... 2001). Analyses of the properties and functions of ncRNAs have indicated that they can act as gene regulators, as part of biotic and abiotic stress signals, or as part of RNA-protein complexes with various enzymatic and structural activities. A number of ncRNAs are processed in an mRNA-like manner; ...
Single-Gene Inheritance Single-Gene Inheritance
... crosses. The central components in this type of analysis are mutants, individual organisms having some altered form of a normal property. The normal form of any property of an organism is called the wild type, that which is found “in the wild,” or in nature. The genetic modus operandi is to mate an ...
... crosses. The central components in this type of analysis are mutants, individual organisms having some altered form of a normal property. The normal form of any property of an organism is called the wild type, that which is found “in the wild,” or in nature. The genetic modus operandi is to mate an ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse