A pair of Sox: distinct and overlapping functions of
... and sox9b transcripts accumulate in overlapping and unique domains. Gene expression, however, does not equate to gene function. The jef mutation destroys sox9a activity (Yan et al., ...
... and sox9b transcripts accumulate in overlapping and unique domains. Gene expression, however, does not equate to gene function. The jef mutation destroys sox9a activity (Yan et al., ...
Maimbo, M., Ohnishi, K., Hikichi, Y., Yoshioka, H. and Kiba, A.
... signal peptide, a bulb lectin domain, and a PAN apple motif. A protein database search showed 99.4%, 30.4%, 25.5%, and 18.1% amino acid identity with its orthologs from N. benthamiana, SGLP from Ipomoea trifida (AAA97903), Medicago truncatula (ABE82226), and ...
... signal peptide, a bulb lectin domain, and a PAN apple motif. A protein database search showed 99.4%, 30.4%, 25.5%, and 18.1% amino acid identity with its orthologs from N. benthamiana, SGLP from Ipomoea trifida (AAA97903), Medicago truncatula (ABE82226), and ...
crosses. - Aurora City Schools
... is a segment of DNA that is located in a chromosome and that codes for a specific trait Crossing over: How does it contribute to the physical differences between siblings? exchange of genetic material between homologous chromosomes genetic recombination Chapter 11 and 14 Genetics 2010 ...
... is a segment of DNA that is located in a chromosome and that codes for a specific trait Crossing over: How does it contribute to the physical differences between siblings? exchange of genetic material between homologous chromosomes genetic recombination Chapter 11 and 14 Genetics 2010 ...
Unit 3 Solutions - Manning`s Science
... and the total size of its genome. An organism may have an enormous number of base pairs in its genome and very few genes if the bulk of its genome consists of non-coding DNA. b. Comparing the genomes of the two organisms would show what genes they have in common, and would indicate their evolutiona ...
... and the total size of its genome. An organism may have an enormous number of base pairs in its genome and very few genes if the bulk of its genome consists of non-coding DNA. b. Comparing the genomes of the two organisms would show what genes they have in common, and would indicate their evolutiona ...
Cover Letter
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
SNP Analysis of the PTC Gene Using PCR
... (Figure 2). This fact was discovered in 1931 in a series of events that involved impressive scientific curiosity and questionable laboratory safety. A chemist named Arthur Fox was mixing a powdered chemical when he accidentally let a bit of the powder blow into the air. A nearby colleague exclaimed h ...
... (Figure 2). This fact was discovered in 1931 in a series of events that involved impressive scientific curiosity and questionable laboratory safety. A chemist named Arthur Fox was mixing a powdered chemical when he accidentally let a bit of the powder blow into the air. A nearby colleague exclaimed h ...
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract
... purpose of component 3 is to evaluate the use of ontologies in a real system. This component could provide a relatively straightforward method for evaluating the quality of ontologies for use in the application. The field of biomedical text mining has expended considerable effort in building evaluat ...
... purpose of component 3 is to evaluate the use of ontologies in a real system. This component could provide a relatively straightforward method for evaluating the quality of ontologies for use in the application. The field of biomedical text mining has expended considerable effort in building evaluat ...
CHAPTER 14 DNA applications in society
... the growth of all body tissues, including bones. hGH was first isolated from human pituitary glands in 1956. By the 1960s, hGH was in clinical use in the treatment of children and adolescents with a particular growth deficiency. This treatment often involved the subcutaneous injection of growth horm ...
... the growth of all body tissues, including bones. hGH was first isolated from human pituitary glands in 1956. By the 1960s, hGH was in clinical use in the treatment of children and adolescents with a particular growth deficiency. This treatment often involved the subcutaneous injection of growth horm ...
Altered cellular proliferation and mesoderm
... 2 week period. For activation assay, splenocytes were seeded at a concentration of 106 cells/ml in a 96-well plate. Cells were incubated in 200 µl of DME, 10% FCS, 10 mM Hepes pH 7.4 solution supplemented with 10 µg/ml of LypoPolySaccharide (LPS, Sigma). After 48 hours of incubation at 37°C, [3H]thy ...
... 2 week period. For activation assay, splenocytes were seeded at a concentration of 106 cells/ml in a 96-well plate. Cells were incubated in 200 µl of DME, 10% FCS, 10 mM Hepes pH 7.4 solution supplemented with 10 µg/ml of LypoPolySaccharide (LPS, Sigma). After 48 hours of incubation at 37°C, [3H]thy ...
Ethylene and Sub1
... • A ‘genetic pathway’ is based on the interactions between gene products that are inferred from the phenotype of mutant combinations • If the double mutant ab looks exactly like the single mutant b, b is said to suppress a. • If locus b suppresses a, B is called epistatic to A. Epistasis suggests th ...
... • A ‘genetic pathway’ is based on the interactions between gene products that are inferred from the phenotype of mutant combinations • If the double mutant ab looks exactly like the single mutant b, b is said to suppress a. • If locus b suppresses a, B is called epistatic to A. Epistasis suggests th ...
KAIE LOKK Comparative genome-wide DNA methylation
... base. Methylated cytosines have a crucial role in mammalian development, and the proportion of methylated CpG sites can vary greatly over a genome. Repeated sequences tend to be the most heavily methylated, while CpG-rich regulatory regions are almost exclusively unmethylated in all human tissues. A ...
... base. Methylated cytosines have a crucial role in mammalian development, and the proportion of methylated CpG sites can vary greatly over a genome. Repeated sequences tend to be the most heavily methylated, while CpG-rich regulatory regions are almost exclusively unmethylated in all human tissues. A ...
Biotechnology Timeline
... Scientists report the birth of Dolly, the first animal cloned from an adult cell. ...
... Scientists report the birth of Dolly, the first animal cloned from an adult cell. ...
Neonatal Hyperbilirubinemia and Organic Anion Transporting
... Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel: +1(212) 584-4662. Received: November 26, 2010. Accepted after revision: February 25, 2011. Published online: April 15, 2011. DOI: http://dx.doi.org/10.1055/s-0031-1276736. ISSN 0735-1631. ...
... Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel: +1(212) 584-4662. Received: November 26, 2010. Accepted after revision: February 25, 2011. Published online: April 15, 2011. DOI: http://dx.doi.org/10.1055/s-0031-1276736. ISSN 0735-1631. ...
Transposable elements in Escherichia coli antimicrobial resistance
... the transposition process, they are automatically amplified, with a large copy number, restricted only by the carrying capacity of their environment (i.e. the genome) [1]. Transposons often persist in genomes over millions of years. This requires an exquisite balance between replication and suppress ...
... the transposition process, they are automatically amplified, with a large copy number, restricted only by the carrying capacity of their environment (i.e. the genome) [1]. Transposons often persist in genomes over millions of years. This requires an exquisite balance between replication and suppress ...
MCScanX`s manual
... homologous relationships detected by third party software. In this case, users should use MCScanX_h instead. The executation of MCScanX_h is very similar to that of MCScanX, except that the "xyz.blast" file should be replaced by "xyz.homology" file. At the bottom of screen output, statistics on numb ...
... homologous relationships detected by third party software. In this case, users should use MCScanX_h instead. The executation of MCScanX_h is very similar to that of MCScanX, except that the "xyz.blast" file should be replaced by "xyz.homology" file. At the bottom of screen output, statistics on numb ...
Modeling Spatial Correlation of DNA Deformation
... proposes to treat DNA as a semiflexible polymer chain that behaves like an elastic rod.17 In this continuous description of DNA, all of the local details of the DNA molecule are coarsegrained into a quadratic bending potential that can be characterized by one single parameter, the bending persistence ...
... proposes to treat DNA as a semiflexible polymer chain that behaves like an elastic rod.17 In this continuous description of DNA, all of the local details of the DNA molecule are coarsegrained into a quadratic bending potential that can be characterized by one single parameter, the bending persistence ...
the PDF file
... can play dramatic roles in shaping geographically or culturally isolated populations, such as Jews. • If the community is small enough, even harmful mutations that drift into the population and tha ...
... can play dramatic roles in shaping geographically or culturally isolated populations, such as Jews. • If the community is small enough, even harmful mutations that drift into the population and tha ...
Replication timing and transcriptional control: beyond
... assays for replication [29]. There are only two mammalian loci for which both replication-timing switches and origin localization have been studied. At the mouse immunoglobulin IgH locus, new origins are activated in pre-B cells when the promoter region of this locus becomes transcriptionally active ...
... assays for replication [29]. There are only two mammalian loci for which both replication-timing switches and origin localization have been studied. At the mouse immunoglobulin IgH locus, new origins are activated in pre-B cells when the promoter region of this locus becomes transcriptionally active ...
Spatially restricted domains of homeo-gene
... (Hox-7,2, -I .3, -I .4, -I .5, -3.7 and -6,7) have been localized in l2|-day mouse embryos. In a comparison of these genes on adjacent or nearby embryo sections, it is found that their transcripts occupy domains which are usually different, although overlaPPing' along the anteroposterior axis of the ...
... (Hox-7,2, -I .3, -I .4, -I .5, -3.7 and -6,7) have been localized in l2|-day mouse embryos. In a comparison of these genes on adjacent or nearby embryo sections, it is found that their transcripts occupy domains which are usually different, although overlaPPing' along the anteroposterior axis of the ...
How the Genetics Calculator Creates Phenotype Names
... The genetics calculator simply omits the loci that have only wild alleles when it displays a genotype. ...
... The genetics calculator simply omits the loci that have only wild alleles when it displays a genotype. ...
Maintenance of DNA Methylation during the Arabidopsis Life Cycle
... detected transcripts from active postzygotic transcription of the FIS2 maternal allele in the endosperm. A putative general paternal silencing has been observed for reporters of endospermexpressed genes for up to 4 DAP (Vielle-Calzada et al., 2000). It could be hypothesized that such a general mecha ...
... detected transcripts from active postzygotic transcription of the FIS2 maternal allele in the endosperm. A putative general paternal silencing has been observed for reporters of endospermexpressed genes for up to 4 DAP (Vielle-Calzada et al., 2000). It could be hypothesized that such a general mecha ...
genome - Sift Desk
... Plants have evolved intricate mechanisms to adapt and respond to the constantly changing environment. Gene expression regulation at the transcriptional level by transcription factors is a key regulation step in all organisms. Data from the Arabidopsis genome project suggested that approximately 5% o ...
... Plants have evolved intricate mechanisms to adapt and respond to the constantly changing environment. Gene expression regulation at the transcriptional level by transcription factors is a key regulation step in all organisms. Data from the Arabidopsis genome project suggested that approximately 5% o ...
Genetic interaction of Lhx4 and Prop1 - Development
... Classical genetic analysis of the LIM gene family reveals similar roles to those of the PITX family (Sheng et al., 1997; Sheng et al., 1996). Both Lhx3 and Lhx4 are expressed in Rathke’s pouch. The Lhx3-deficient phenotype is similar to that of Pitx2, consisting of pouch hypoplasia and absence of mo ...
... Classical genetic analysis of the LIM gene family reveals similar roles to those of the PITX family (Sheng et al., 1997; Sheng et al., 1996). Both Lhx3 and Lhx4 are expressed in Rathke’s pouch. The Lhx3-deficient phenotype is similar to that of Pitx2, consisting of pouch hypoplasia and absence of mo ...
A SNP in the ABCC11 gene is the determinant of human earwax type
... GG homozygotes at each of the three SNP loci (Table 1 and Supplementary Table 1 online). Among the SNPs, only rs17822931 is nonsynonymous (G180R); rs6500380 does not create any splicing sites nor affect splicing factor binding motifs or known promoter sequences, and ss49784070 is located within the ...
... GG homozygotes at each of the three SNP loci (Table 1 and Supplementary Table 1 online). Among the SNPs, only rs17822931 is nonsynonymous (G180R); rs6500380 does not create any splicing sites nor affect splicing factor binding motifs or known promoter sequences, and ss49784070 is located within the ...
Genetic interaction of Lhx4 and Prop1
... Classical genetic analysis of the LIM gene family reveals similar roles to those of the PITX family (Sheng et al., 1997; Sheng et al., 1996). Both Lhx3 and Lhx4 are expressed in Rathke’s pouch. The Lhx3-deficient phenotype is similar to that of Pitx2, consisting of pouch hypoplasia and absence of mo ...
... Classical genetic analysis of the LIM gene family reveals similar roles to those of the PITX family (Sheng et al., 1997; Sheng et al., 1996). Both Lhx3 and Lhx4 are expressed in Rathke’s pouch. The Lhx3-deficient phenotype is similar to that of Pitx2, consisting of pouch hypoplasia and absence of mo ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse