How to obtain and recognize partial-diploid strains that are duplicated... chromosome segments.
... Experiments can be designed to allow recognition of duplication progeny by marker phenotype. (This is especially useful with unstable duplications that break down to give fertile heterokaryons). If a duplication-generating strain that carries a recessive marker located in the translocated segment is ...
... Experiments can be designed to allow recognition of duplication progeny by marker phenotype. (This is especially useful with unstable duplications that break down to give fertile heterokaryons). If a duplication-generating strain that carries a recessive marker located in the translocated segment is ...
Cluster Analysis for Gene Expression Data
... indicated a relatively small and redundant collection of conditions suffice to separate genes into functional categories, the addition of more and diverse conditions can only enhance those observation [Eisen1998]. Eisen et. al. applied a hierarchical clustering algorithm to two sets of data: gene e ...
... indicated a relatively small and redundant collection of conditions suffice to separate genes into functional categories, the addition of more and diverse conditions can only enhance those observation [Eisen1998]. Eisen et. al. applied a hierarchical clustering algorithm to two sets of data: gene e ...
Anther Development
... anther is established, cell and tissue differentiation occur, and microspore mother cells undergo meiosis. At the end of phase 1, the anther contains most of its specialized cells and tissues, and tetrads of microspores are present within the pollen sacs (Figure 1). During phase 2, pollen grains dif ...
... anther is established, cell and tissue differentiation occur, and microspore mother cells undergo meiosis. At the end of phase 1, the anther contains most of its specialized cells and tissues, and tetrads of microspores are present within the pollen sacs (Figure 1). During phase 2, pollen grains dif ...
Genotype–phenotype correlations in nemaline myopathy caused by
... In both groups, muscle weakness was generalised, usually symmetrical, and most pronounced in the neck flexors (Figs. 1 and 2). In the nebulin group, the ankle dorsiflexors were very weak also, while the extensors of the knees were well preserved in comparison with the knee flexors. In the actin grou ...
... In both groups, muscle weakness was generalised, usually symmetrical, and most pronounced in the neck flexors (Figs. 1 and 2). In the nebulin group, the ankle dorsiflexors were very weak also, while the extensors of the knees were well preserved in comparison with the knee flexors. In the actin grou ...
Statistical analysis of DNA microarray data
... • Which genes to use for normalization • Housekeeping genes • Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation • These genes will be similarly expressed in all samples. • Difficult to identify – need to be confirmed • Affymetrix Gene ...
... • Which genes to use for normalization • Housekeeping genes • Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation • These genes will be similarly expressed in all samples. • Difficult to identify – need to be confirmed • Affymetrix Gene ...
Guidelines for interpretation of 16S rRNA gene sequence
... genes of Staphylococcus aureus, rather than other strains of Staphylococcus haemolyticus, and no results of phenotypic characterization were given for this strain. Therefore, the true identity of this strain is difficult to ascertain. In the present study and a previous one (Woo et al., 2007), we us ...
... genes of Staphylococcus aureus, rather than other strains of Staphylococcus haemolyticus, and no results of phenotypic characterization were given for this strain. Therefore, the true identity of this strain is difficult to ascertain. In the present study and a previous one (Woo et al., 2007), we us ...
osteogenesis imperfecta
... include the presence of blue sclera, dentinogenesis imperfecta, skin hyperlaxity and joint hypermobility. These are all features that one might expect to be associated with a disorder involving type I collagen, though such a relationship is not absolute. While individuals with OI having blue sclera ...
... include the presence of blue sclera, dentinogenesis imperfecta, skin hyperlaxity and joint hypermobility. These are all features that one might expect to be associated with a disorder involving type I collagen, though such a relationship is not absolute. While individuals with OI having blue sclera ...
University of Groningen DNA-based asymmetric catalysis
... generally still outperformed by enzymes. However, the possibility to catalyze a wide variety of reactions, renders small molecule catalysts very important for applications of asymmetric catalysis in industry,8 and on smaller scale in total synthesis.9 The solvents of choice for small molecule cataly ...
... generally still outperformed by enzymes. However, the possibility to catalyze a wide variety of reactions, renders small molecule catalysts very important for applications of asymmetric catalysis in industry,8 and on smaller scale in total synthesis.9 The solvents of choice for small molecule cataly ...
Detection of cystic fibrosis transmembrane conductance regulator
... alleles), as well as patients with two putative allelic mutations, because their effect may not be deleterious enough to account for the disease or because homozygous status could not be confirmed by family analysis (0 – 18 unidentified alleles). The four rearrangements accounted for nearly 7% of th ...
... alleles), as well as patients with two putative allelic mutations, because their effect may not be deleterious enough to account for the disease or because homozygous status could not be confirmed by family analysis (0 – 18 unidentified alleles). The four rearrangements accounted for nearly 7% of th ...
- Wiley Online Library
... The Sz. pombe Vps33 protein is required for vacuolar fusion in vivo Isolated vacuoles from S. cerevisiae can undergo fusion in vitro (Wickner, 2002; Wickner and Haas, 2000). One factor required for this process is the class C Vps complex (Sato et al., 2000). Under normal conditions, Sz. pombe has a ...
... The Sz. pombe Vps33 protein is required for vacuolar fusion in vivo Isolated vacuoles from S. cerevisiae can undergo fusion in vitro (Wickner, 2002; Wickner and Haas, 2000). One factor required for this process is the class C Vps complex (Sato et al., 2000). Under normal conditions, Sz. pombe has a ...
Structural Variants in the Human Genome
... 350 base pairs in length Contain an RNA Polymerase III promoter, Alu site Appear to evolve from 7S RNA signal recognition particle ...
... 350 base pairs in length Contain an RNA Polymerase III promoter, Alu site Appear to evolve from 7S RNA signal recognition particle ...
Chromosome Theory
... XXY - Klinefelter’s Syndrome - Phenotypically male Of the non-sex chromosome aneuploidys, Down’s Syndrome, extra chromosome 21, tends to be the most viable Down’s Syndrome is more common in children of mothers who gave birth after age 40 ©1999 Timothy G. Standish ...
... XXY - Klinefelter’s Syndrome - Phenotypically male Of the non-sex chromosome aneuploidys, Down’s Syndrome, extra chromosome 21, tends to be the most viable Down’s Syndrome is more common in children of mothers who gave birth after age 40 ©1999 Timothy G. Standish ...
The rapidly evolving field of plant centromeres
... Mathematical models predict that low levels of homologous recombination cause the accumulation of repetitive elements [31,32], but a study that considered only non-coding Arabidopsis DNA found no correlation between meiotic recombination frequencies and the distribution of most transposable elements ...
... Mathematical models predict that low levels of homologous recombination cause the accumulation of repetitive elements [31,32], but a study that considered only non-coding Arabidopsis DNA found no correlation between meiotic recombination frequencies and the distribution of most transposable elements ...
Birefringence imaging of spermatozoa, spindle and zona pellucida
... by Engelmann Engelmann, 1875 • Negative birefringence of the sperm head related to chromatin orientation (Schmidt (Schmidt, 1924, 1937; Pattri 1932) • Inoué I é was the h fi first to show h that h polarization l i i microscopy can be used to identify acrosome-reacted d spermatozoa (1981) ...
... by Engelmann Engelmann, 1875 • Negative birefringence of the sperm head related to chromatin orientation (Schmidt (Schmidt, 1924, 1937; Pattri 1932) • Inoué I é was the h fi first to show h that h polarization l i i microscopy can be used to identify acrosome-reacted d spermatozoa (1981) ...
8th grade Chapter 8
... the entire genetic information that is needed to form every one of your characteristics. C. When organisms sexually reproduce, genetic information is passed down from each biological parent to their offspring. D. In other words, one DNA chromosome from each pair is inherited from each biological par ...
... the entire genetic information that is needed to form every one of your characteristics. C. When organisms sexually reproduce, genetic information is passed down from each biological parent to their offspring. D. In other words, one DNA chromosome from each pair is inherited from each biological par ...
Document
... the genomic inflation factor in this analysis was 2.75. This extremely high value was caused by two factors: (1) to a large extent by the use of highly stratified and sometimes closely related samples and (2) to a small extent the fact that a relatively large portion of the genome showed an associat ...
... the genomic inflation factor in this analysis was 2.75. This extremely high value was caused by two factors: (1) to a large extent by the use of highly stratified and sometimes closely related samples and (2) to a small extent the fact that a relatively large portion of the genome showed an associat ...
SARS Outbreaks in Ontario, Hong Kong and Singapore: the role of
... (two biological advantages: maintaining chromosome number unchanged and crossing over between different genes) • Crossover: The interchange of sections between pairing homologous chromosomes during meiosis • Recombination, recombinant, recombination fraction (rate, frequency): The natural formation ...
... (two biological advantages: maintaining chromosome number unchanged and crossing over between different genes) • Crossover: The interchange of sections between pairing homologous chromosomes during meiosis • Recombination, recombinant, recombination fraction (rate, frequency): The natural formation ...
Genes Critical for Muscle Development and Function in
... Three-factor analysis and duplications and deficiencies were used for more detailed mapping. The three-factor data were generated using standard techniques (Wood et al., 1988) and are presented in Table I. The X-linked mutationpat-9(st558) was shown to be included in duplications mnDpl and mnDp8 by ...
... Three-factor analysis and duplications and deficiencies were used for more detailed mapping. The three-factor data were generated using standard techniques (Wood et al., 1988) and are presented in Table I. The X-linked mutationpat-9(st558) was shown to be included in duplications mnDpl and mnDp8 by ...
POTE Paralogs Are Induced and Differentially Expressed in Many
... genome (6). The proteins encoded by the POTE genes all have an NH2terminal cysteine-rich domain followed by a series of ankyrin repeats and spectrin-like helices. The various POTE mRNAs are spliced in different ways so that the proteins encoded by these RNAs vary in size from 32 to 80 kDa (7). The P ...
... genome (6). The proteins encoded by the POTE genes all have an NH2terminal cysteine-rich domain followed by a series of ankyrin repeats and spectrin-like helices. The various POTE mRNAs are spliced in different ways so that the proteins encoded by these RNAs vary in size from 32 to 80 kDa (7). The P ...
Point Mutation Analysis of PMP22 in Patients Referred for Hereditary
... causality (loss of PMP22 function) for the three unclassified amino acid substitutions (c.328G>A p.(Val110Met), c.392C>G p.(Ser131Cys) and c.395A>G p.(Tyr132Cys)), while the c.320-1_320delGGinsTA (destruction of splice site) and c.434delT (protein reading frame shift) mutations are clearly deleterio ...
... causality (loss of PMP22 function) for the three unclassified amino acid substitutions (c.328G>A p.(Val110Met), c.392C>G p.(Ser131Cys) and c.395A>G p.(Tyr132Cys)), while the c.320-1_320delGGinsTA (destruction of splice site) and c.434delT (protein reading frame shift) mutations are clearly deleterio ...
Submitting an RNA-Seq job at PATRIC
... 1. At the top of any PATRIC page, find the Services tab. ...
... 1. At the top of any PATRIC page, find the Services tab. ...
Glassman, S.
... most of the recessive mutants, while the balancing X-chromosome is supplied with of ptg oc. Moreover, the fertile females contain a Y-chromosome, of normal type. The X-chromosome of the fertile males has the composition y oc ptg lz f. As in the stocks "jynd" and "plond" (f72 and f88, respectively, o ...
... most of the recessive mutants, while the balancing X-chromosome is supplied with of ptg oc. Moreover, the fertile females contain a Y-chromosome, of normal type. The X-chromosome of the fertile males has the composition y oc ptg lz f. As in the stocks "jynd" and "plond" (f72 and f88, respectively, o ...
Molecular diversity of thermophilic bacteria isolated from Pasinler
... In total 14 different FAMEs were detected in the 9 bacterial strains tested in the present study (Table). Five of these, 15:0 iso, 15:0 anteiso, 16:0 iso, 17:0 iso, and 17:0 anteiso fatty acids, appeared in all strains. However, 17:1 iso w10c fatty acid was only present in the P38 strain. Bacterial ...
... In total 14 different FAMEs were detected in the 9 bacterial strains tested in the present study (Table). Five of these, 15:0 iso, 15:0 anteiso, 16:0 iso, 17:0 iso, and 17:0 anteiso fatty acids, appeared in all strains. However, 17:1 iso w10c fatty acid was only present in the P38 strain. Bacterial ...
University of Birmingham Immunolabelling of human metaphase
... It remains uncertain whether the patterns of histone modification that define individual chromosome bands are a simple reflection of gene richness and/or ongoing transcription, or whether they play a determining role in chromatin packaging and intra-nuclear location at the Mb level. In this respect, ...
... It remains uncertain whether the patterns of histone modification that define individual chromosome bands are a simple reflection of gene richness and/or ongoing transcription, or whether they play a determining role in chromatin packaging and intra-nuclear location at the Mb level. In this respect, ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse