Meiosis II
... 1. Somatic Cells are “body” cells and contain the normal number of chromosomes ….called the “Diploid” number (the symbol is 2n). Examples would be … skin cells, brain cells, etc. 2. Gametes are the “sex” cells and contain only half the normal number of chromosomes…. called the “Haploid” number (the ...
... 1. Somatic Cells are “body” cells and contain the normal number of chromosomes ….called the “Diploid” number (the symbol is 2n). Examples would be … skin cells, brain cells, etc. 2. Gametes are the “sex” cells and contain only half the normal number of chromosomes…. called the “Haploid” number (the ...
Recent advances in the molecular genetics of congenital
... Fig. 1 Demonstration of a 13 base-pair deletion (964del13) at nucleotide 964 in the autoimmune regulator gene (AIRE-1) in two UK families with autoimmune polyendocrinopathy type 1 (APS1). (a) shows the wild-type (WT) and the mutant (M) (964del13) DNA sequences. This deletion abolishes the recognitio ...
... Fig. 1 Demonstration of a 13 base-pair deletion (964del13) at nucleotide 964 in the autoimmune regulator gene (AIRE-1) in two UK families with autoimmune polyendocrinopathy type 1 (APS1). (a) shows the wild-type (WT) and the mutant (M) (964del13) DNA sequences. This deletion abolishes the recognitio ...
Conservation Genetics of Wolves and their Relationship with Dogs
... habitat. Captive breeding programs aim at retaining high levels of genetic diversity. The long term goal for many breeding programs is reintroduction of the species into the wild. However, adaptation to live in captivity might reduce fitness when populations are returned to the wild (Frankham 2005). ...
... habitat. Captive breeding programs aim at retaining high levels of genetic diversity. The long term goal for many breeding programs is reintroduction of the species into the wild. However, adaptation to live in captivity might reduce fitness when populations are returned to the wild (Frankham 2005). ...
The biased nucleotide composition of the HIV genome: a constant
... requirement of specific tRNA species and in the preference for amino acids encoded by e.g. A-rich codons. Nucleotide composition does obviously affect the secondary and tertiary structure of the RNA genome and its biological functions, but it does also influence phylogenetic analysis of viral genome ...
... requirement of specific tRNA species and in the preference for amino acids encoded by e.g. A-rich codons. Nucleotide composition does obviously affect the secondary and tertiary structure of the RNA genome and its biological functions, but it does also influence phylogenetic analysis of viral genome ...
Candidate genes for growth traits in beef cattle crosses Bos
... Fig. 1. Interaction of LGB and GH genotypes for GWY. (Axis X ¼ LGB genotypes, Axis Y ¼ GWY (kg)) ...
... Fig. 1. Interaction of LGB and GH genotypes for GWY. (Axis X ¼ LGB genotypes, Axis Y ¼ GWY (kg)) ...
Pain Genes?: Natural Variation and Transgenic Mutants
... innocuous stimuli (allodynia); this ensures that the injured part of the body is protected. This process involves molecules that sensitize the primary afferent and second order spinal cord neurons to innocuous stimuli. Finally, there are conditions in which pain is maladaptive; in these conditions, ...
... innocuous stimuli (allodynia); this ensures that the injured part of the body is protected. This process involves molecules that sensitize the primary afferent and second order spinal cord neurons to innocuous stimuli. Finally, there are conditions in which pain is maladaptive; in these conditions, ...
BRCA2 and p53 Mutations in Primary Breast
... notion of BRCA2 involvement in double-strand DNA repair. It is well known that p53 participates in cell cycle control by activating p21 in response to DNA damage (29). It has been shown that the expression of the BRCA genes is cell cycle dependent (5, 30), and in a recent study, BRCAI was found to a ...
... notion of BRCA2 involvement in double-strand DNA repair. It is well known that p53 participates in cell cycle control by activating p21 in response to DNA damage (29). It has been shown that the expression of the BRCA genes is cell cycle dependent (5, 30), and in a recent study, BRCAI was found to a ...
Overrepresentation of the COL3A1 AA genotype in Polish skiers with
... Skiing as a recreational activity has increased exponentially in recent ...
... Skiing as a recreational activity has increased exponentially in recent ...
Mutations in Escherichiu coZi that Mutations Distant
... 4 2 on minimal medium containing indole in the absence of 5-methyltryptophan. 5-Methyltryptophan is an inducer of tryptophanase, an enzyme that catalyses the conversion: L-tryptophan + indole pyruvate NH,. The usual function of this enzyme in E. coli is believed to be to degrade tryptophan, but the ...
... 4 2 on minimal medium containing indole in the absence of 5-methyltryptophan. 5-Methyltryptophan is an inducer of tryptophanase, an enzyme that catalyses the conversion: L-tryptophan + indole pyruvate NH,. The usual function of this enzyme in E. coli is believed to be to degrade tryptophan, but the ...
Growth medium composition-determined regulatory mechanisms
... and thereafter diluted into fresh LB medium as indicated above. To induce the expression of CatR, IPTG (at a final concentration of 0n5 mM) was added to the growth medium. When the culture reached the exponential growth phase, it was diluted again into fresh LB medium containing 0n5 mM IPTG. At this ...
... and thereafter diluted into fresh LB medium as indicated above. To induce the expression of CatR, IPTG (at a final concentration of 0n5 mM) was added to the growth medium. When the culture reached the exponential growth phase, it was diluted again into fresh LB medium containing 0n5 mM IPTG. At this ...
A versatile toolbox for PCR-based tagging of yeast genes: new
... Copyright 2004 John Wiley & Sons, Ltd. ...
... Copyright 2004 John Wiley & Sons, Ltd. ...
Poster: Litter size in Norwegian White Sheep
... the litter size by approximately 0.3 lambs per copy of the allele. The variance in litter size increases with the mean. 850 ewes from flocks with both a high genetic level for litter size and phenotypically large litters were genotyped. 54% of the three year old ewes with two copies of the allele ha ...
... the litter size by approximately 0.3 lambs per copy of the allele. The variance in litter size increases with the mean. 850 ewes from flocks with both a high genetic level for litter size and phenotypically large litters were genotyped. 54% of the three year old ewes with two copies of the allele ha ...
Chapter 2 Patterns of Inheritance Chapter 2 Patterns of Inheritance
... of the pair and the other half of the gametes carry the other member of the pair. Now we need to introduce some more terms. The individuals represented by A /a are called heterozygotes or, sometimes, hybrids, whereas the individuals in pure lines are called homozygotes. In such words, hetero- means ...
... of the pair and the other half of the gametes carry the other member of the pair. Now we need to introduce some more terms. The individuals represented by A /a are called heterozygotes or, sometimes, hybrids, whereas the individuals in pure lines are called homozygotes. In such words, hetero- means ...
Two groups of human herpesvirus 6 identified by sequence
... As HHV-6 has a tropism similar to that of human immunodeficiency virus (HIV) in infections of CD4 ÷ T lymphocytes and monocytes/macrophages (Yamanishi et al., 1988; Okuno et al., 1989; Levy et al., 1990a; Kondo et al., 1991; Wrzos et al., 1990), it has been suggested that HHV-6 may reactivate and pa ...
... As HHV-6 has a tropism similar to that of human immunodeficiency virus (HIV) in infections of CD4 ÷ T lymphocytes and monocytes/macrophages (Yamanishi et al., 1988; Okuno et al., 1989; Levy et al., 1990a; Kondo et al., 1991; Wrzos et al., 1990), it has been suggested that HHV-6 may reactivate and pa ...
Nonrandom cell-cycle timing of a somatic chromosomal
... those resulting in a der(17) in females are shown. There are two possible mechanisms by which a G1 translocation could result in a der(17): (A) translocation followed by loss of the der(X) and duplication or missegregation of the normal homolog, resulting in LOH for Xq loci; and (B) trisomy X preced ...
... those resulting in a der(17) in females are shown. There are two possible mechanisms by which a G1 translocation could result in a der(17): (A) translocation followed by loss of the der(X) and duplication or missegregation of the normal homolog, resulting in LOH for Xq loci; and (B) trisomy X preced ...
The genetic epidemiology of idiopathic scoliosis
... matrix. The genes encoding fibrillin (FBN1), elastin (ELN), collagen I A1 and A2 (COL1A1, COL1A2), collagen II A1 (COL2A1), and aggrecan (ACAN), showed no association with IS on linkage analysis and/or transmission disequilibrium testing [14–16, 18]. Interestingly, using 50 informative Italian trios ...
... matrix. The genes encoding fibrillin (FBN1), elastin (ELN), collagen I A1 and A2 (COL1A1, COL1A2), collagen II A1 (COL2A1), and aggrecan (ACAN), showed no association with IS on linkage analysis and/or transmission disequilibrium testing [14–16, 18]. Interestingly, using 50 informative Italian trios ...
The Ehlers-Danlos syndrome: on beyond collagens
... Since publication of our initial report, we have identified two additional patients with CAH and EDS, and all three patients have similar EDS phenotypes (our unpublished results). The essential features are typical skin and joint hyperextensibility and easy bruising. Features that may distinguish th ...
... Since publication of our initial report, we have identified two additional patients with CAH and EDS, and all three patients have similar EDS phenotypes (our unpublished results). The essential features are typical skin and joint hyperextensibility and easy bruising. Features that may distinguish th ...
Nondisjunction and chromosomal anomalies La no disyunción y las
... structure or chromosome number. Variation in chromosome number includes aneuploids, which do not involve whole sets of chromosomes (genomes) but only parts of a set (genome) (aneu-uneven; ploid-unit). They may be of the following types: Monosomy; diploid organisms which lack one chromosome of a sin ...
... structure or chromosome number. Variation in chromosome number includes aneuploids, which do not involve whole sets of chromosomes (genomes) but only parts of a set (genome) (aneu-uneven; ploid-unit). They may be of the following types: Monosomy; diploid organisms which lack one chromosome of a sin ...
Light and temperature affect the expression of two candidate genes
... carbon, grew faster and survived better than those with unmatched periods. Molecular genetic analyses of Arabidopsis have identified photoreceptors, light-signalling components and components from the circadian system as essential for the photoperiodic response. A three-stage model consisting of an ...
... carbon, grew faster and survived better than those with unmatched periods. Molecular genetic analyses of Arabidopsis have identified photoreceptors, light-signalling components and components from the circadian system as essential for the photoperiodic response. A three-stage model consisting of an ...
Phenotypic data in FlyBase
... to learn to annotate the output of largescale genome-sequencing projects accurately and meaningfully. Current efforts to de®ne gene function are focused on protein coding regions. Methods of assigning function have relied on sequence comparisons of coding regions and extrapolation of function from a ...
... to learn to annotate the output of largescale genome-sequencing projects accurately and meaningfully. Current efforts to de®ne gene function are focused on protein coding regions. Methods of assigning function have relied on sequence comparisons of coding regions and extrapolation of function from a ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse