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Operon
Operon

... Translational gene regulation  Control of how often and how rapidly mRNA transcripts are translated into proteins Posttranslational gene regulation  Modifications made to the polypeptide chain ...
Genes
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... on and off in different cells. (There are other mechanisms as well but this is our focus.) E.g. globin genes are expressed only in erythroblasts and are turned off in muscle cells. Myosin genes are on in muscle cells but off in erythrocytes. Progression through the cell cycle also requires turning d ...
Unit 4. Week 2. Meiosis and Reproduction
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Body maps on the human genome | SpringerLink
Body maps on the human genome | SpringerLink

... relationship between tissue-locations in the body and gene-positions in the genome significantly fits a simple linear model. (If the brain datapoint is excluded from the analysis, the correlation still remains significant, dropping (from r2 = 0.62) to r2 = 0.53; p < 0.04, two-tailed.) The dorso-vent ...
Analysis of P-element disrupted gene expressions in the eye
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... Xn = m for m = 3 and m = 4. That is, compute ρim for all i = 0, . . . , m for those two cases. (Note: I’m asking for m = 3 or 4, not k = 3 or 4.) Can you guess the form of the answer in general? (c) Check that your guess in part (b) satisfies the equations for hitting probabilities for general m. I ...
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... 1. Compare the structure and organization of prokaryotic and eukaryotic genomes. 2. Describe the current model for progressive levels of DNA packing in eukaryotes. 3. Explain how histones influence folding in eukaryotic DNA. 4. Distinguish between heterochromatin and euchromatin. The Control of Gene ...
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... determine the phenotype of an organism. Two parameters describe the effects: Penetrance is the proportion of individuals with a certain genotype that show the phenotype. Expressivity is the degree to which genotype is expressed in an individual. ...
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Introduction to Genetics - Cherokee County Schools

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Introduction to DNA

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Molecular biology Tools

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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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