Presentation
... – The major mechanism of DSB repair – Used physiologically in VDJ rejoining of T cell and Ig receptors – Mammalian mutants deficient in NHEJ are deficient in DNA repair and immunity (severe combined immune deficiency scid - in mice and humans) – The major molecular players are: • Ku70/Ku80 - Artemis ...
... – The major mechanism of DSB repair – Used physiologically in VDJ rejoining of T cell and Ig receptors – Mammalian mutants deficient in NHEJ are deficient in DNA repair and immunity (severe combined immune deficiency scid - in mice and humans) – The major molecular players are: • Ku70/Ku80 - Artemis ...
Ernest Just - CPO Science
... In some situations, this method for writing whole-number ratios does not provide enough information. In the example of Jerod going out with his family for dinner and a movie, if only the estimated whole-number ratio (2:1) is given, we might believe that his family spent twice as much money on food a ...
... In some situations, this method for writing whole-number ratios does not provide enough information. In the example of Jerod going out with his family for dinner and a movie, if only the estimated whole-number ratio (2:1) is given, we might believe that his family spent twice as much money on food a ...
Evolution at the Subgene Level: Domain Rearrangements in
... rearrangement across nine sequenced species, along with possible mechanisms for their formation. These results dramatically expand on evolution at the subgene level and offer several insights into how new genes and functions arise between species. ...
... rearrangement across nine sequenced species, along with possible mechanisms for their formation. These results dramatically expand on evolution at the subgene level and offer several insights into how new genes and functions arise between species. ...
Efficient Virus-Induced Gene Silencing in Roots
... has seldom been studied (Palauqui et al., 1997; Dalmay et al., 2000; Sonoda and Nishiguchi, 2000; Valentine et al., 2002; Saedler and Baldwin, 2004). Previous investigations of tobacco mosaic virus movement and repression within N. benthamiana, together with the silencing of the 35STgfp transgene in ...
... has seldom been studied (Palauqui et al., 1997; Dalmay et al., 2000; Sonoda and Nishiguchi, 2000; Valentine et al., 2002; Saedler and Baldwin, 2004). Previous investigations of tobacco mosaic virus movement and repression within N. benthamiana, together with the silencing of the 35STgfp transgene in ...
Case report - HAL
... gene, encoding HNF1 (3). These mutations are inactivating and both alleles are mutated in tumors. Patients with an inherited mutation in one allele of HNF1 may develop maturity onset diabetes of the young type 3 (MODY3, OMIM#600496) and familial liver adenomatosis, when the second allele is inacti ...
... gene, encoding HNF1 (3). These mutations are inactivating and both alleles are mutated in tumors. Patients with an inherited mutation in one allele of HNF1 may develop maturity onset diabetes of the young type 3 (MODY3, OMIM#600496) and familial liver adenomatosis, when the second allele is inacti ...
- Genetics
... For two genes, E241 and E284, however, some results suggested potential paralogues. The supporting text (File S1) describes these results, together with evidence that E241 segregates as a single-copy gene. For E284, a paralogous copy was detected. One copy, denoted by E284PAR, segregates as a PAR ge ...
... For two genes, E241 and E284, however, some results suggested potential paralogues. The supporting text (File S1) describes these results, together with evidence that E241 segregates as a single-copy gene. For E284, a paralogous copy was detected. One copy, denoted by E284PAR, segregates as a PAR ge ...
Major influence of repetitive elements on disease
... A recurrent deletion of 1.6 to 1.8 Mb (>95 % of the patients) at the 7q11.23 locus causes the Williams-Beuren syndrome (OMIM #194050) [6]. Genes within this region are dosage-sensitive and the recurrently deleted region encompasses a total of 28 genes. This locus is characterized by highly homologou ...
... A recurrent deletion of 1.6 to 1.8 Mb (>95 % of the patients) at the 7q11.23 locus causes the Williams-Beuren syndrome (OMIM #194050) [6]. Genes within this region are dosage-sensitive and the recurrently deleted region encompasses a total of 28 genes. This locus is characterized by highly homologou ...
Physical map of the aromatic amine and m-toluate
... present in Pseudomonasputida UCC22, a derivativeof P.putida mt-2. The plasmid is 79 1kbp in size and can be divided into a restriction-site-deficient region of 51 f 1 kbp and a restriction-site-profuse region of 28 kbp which begins and ends with directly repeating sequences of at least 2 kbp in leng ...
... present in Pseudomonasputida UCC22, a derivativeof P.putida mt-2. The plasmid is 79 1kbp in size and can be divided into a restriction-site-deficient region of 51 f 1 kbp and a restriction-site-profuse region of 28 kbp which begins and ends with directly repeating sequences of at least 2 kbp in leng ...
TUTORIAL 8 – DNA - Molecular Movies
... create a particle at every sphere (jPivToParticle created by Julian Mann) and then use the blobby sphere render type to render the DNA. An important note before we jump into this section – this part of the tutorial is heavily influenced by THE original tutorial on the use of these scripts: Eric Kell ...
... create a particle at every sphere (jPivToParticle created by Julian Mann) and then use the blobby sphere render type to render the DNA. An important note before we jump into this section – this part of the tutorial is heavily influenced by THE original tutorial on the use of these scripts: Eric Kell ...
SNP Set Analysis for Detecting Disease Association Using Exon
... p-value is less than 0.1. Throughout the 100 pairs of screening and test data sets, if threshold 0.1 is used in the screening step, then four genes (FLT1, PIK3C3, KDR, PRR4) are selected for more than 10 times by at least one of the five testing methods. In contrast, if no screening is employed (i.e ...
... p-value is less than 0.1. Throughout the 100 pairs of screening and test data sets, if threshold 0.1 is used in the screening step, then four genes (FLT1, PIK3C3, KDR, PRR4) are selected for more than 10 times by at least one of the five testing methods. In contrast, if no screening is employed (i.e ...
Volume 11 - Número 6 - Novembro / Dezembro de 2001
... echocardiography and Doppler ultrasound examination and/or left heart catheterization(14). Clinical findings include supravalvar aortic stenosis, a congenital narrowing of the ascending aorta, either localized or diffuse, originating at the superior margin of the sinuses of Valsalva just above the l ...
... echocardiography and Doppler ultrasound examination and/or left heart catheterization(14). Clinical findings include supravalvar aortic stenosis, a congenital narrowing of the ascending aorta, either localized or diffuse, originating at the superior margin of the sinuses of Valsalva just above the l ...
Visualizing expression patterns of Shh and Foxf1 genes
... 9]. Homozygous Shh mutant mouse embryos are characterized by a number of development defects; especially in the respiratory tract that include failure of the trachea to develop as a separate structure from the oesophagus [8, 10]. In Adriamycin treated rats, the level of Shh protein expression is ver ...
... 9]. Homozygous Shh mutant mouse embryos are characterized by a number of development defects; especially in the respiratory tract that include failure of the trachea to develop as a separate structure from the oesophagus [8, 10]. In Adriamycin treated rats, the level of Shh protein expression is ver ...
Diversity of DNA methyltransferases that recognize asymmetric
... 1997), and M.MboIIA (Osipiuk et al., 2003) were crystallized as protein dimers. However, further biochemical and structural studies are required to confirm the relevance of this dimerization. The extent of subunit contacts observed in the crystal structure of M.MboIIA suggested that the two molecule ...
... 1997), and M.MboIIA (Osipiuk et al., 2003) were crystallized as protein dimers. However, further biochemical and structural studies are required to confirm the relevance of this dimerization. The extent of subunit contacts observed in the crystal structure of M.MboIIA suggested that the two molecule ...
5.1.2 Meiosis and Variation
... The type of natural selection that can produce the type of speciation that has occurred in seahorses is known as disruptive selection. This is where the extreme phenotypes are more likely to survive and reproduce than the intermediate phenotypes. ...
... The type of natural selection that can produce the type of speciation that has occurred in seahorses is known as disruptive selection. This is where the extreme phenotypes are more likely to survive and reproduce than the intermediate phenotypes. ...
No Slide Title
... The Genetics Education Project * Health care providers must use their own clinical judgment in addition to the information presented herein. The authors assume no responsibility or liability resulting from the use of information in this presentation. The Genetics Education Project ...
... The Genetics Education Project * Health care providers must use their own clinical judgment in addition to the information presented herein. The authors assume no responsibility or liability resulting from the use of information in this presentation. The Genetics Education Project ...
The Evo-Devo Puzzle of Human Hair Patterning
... their scalp hair, and other body regions can vary independently as well (Miller 1931). Is it possible that evolution merged our command center for hair color with our headquarters for hair patterning? Our master gene for skin pigmentation is MC1R (Hoekstra 2006; Lin and Fisher 2007). It encodes the ...
... their scalp hair, and other body regions can vary independently as well (Miller 1931). Is it possible that evolution merged our command center for hair color with our headquarters for hair patterning? Our master gene for skin pigmentation is MC1R (Hoekstra 2006; Lin and Fisher 2007). It encodes the ...
Biogenesis of trans-acting siRNAs, endogenous
... sorting of miR390 to AGO7 occurs remains unknown. THO/TREX complex The accumulation of tasiRNAs decreases in loss-of-function mutants of the THO/TREX complex (Jauvion et al., 2010; Yelina et al., 2010). The THO/TREX complex is composed of multiple subunits that participate in the transportation of m ...
... sorting of miR390 to AGO7 occurs remains unknown. THO/TREX complex The accumulation of tasiRNAs decreases in loss-of-function mutants of the THO/TREX complex (Jauvion et al., 2010; Yelina et al., 2010). The THO/TREX complex is composed of multiple subunits that participate in the transportation of m ...
Interspecies Bacterial Conjugation by Plasmids from Marine
... Vibrio sp. S14, 1%–5% of the number of transconjugants recovered on selective media was detected by direct microscopy after 24 h for both plasmid pBF1 and plasmid pB7. The same was true for the pBF1 transconjugants of D. marina, whereas 15% of the pB7 transconjugants recovered on selective media wer ...
... Vibrio sp. S14, 1%–5% of the number of transconjugants recovered on selective media was detected by direct microscopy after 24 h for both plasmid pBF1 and plasmid pB7. The same was true for the pBF1 transconjugants of D. marina, whereas 15% of the pB7 transconjugants recovered on selective media wer ...
Nitrogen Fixation In Methanogens: The Archaeal
... transcription in methanogens appears to be regulated directly by this common nitrogen mechanism, it may not have an additional level of regulation specific to nitrogen fixation, as is the case involving NifA in Proteobacteria. However, there does appear to be a post-transcriptional mechanism specifi ...
... transcription in methanogens appears to be regulated directly by this common nitrogen mechanism, it may not have an additional level of regulation specific to nitrogen fixation, as is the case involving NifA in Proteobacteria. However, there does appear to be a post-transcriptional mechanism specifi ...
Package `acde` - USTC Open Source Software Mirror
... Description This package provides a multivariate inferential analysis method for detecting differentially expressed genes in gene expression data. It uses artificial components, close to the data's principal components but with an exact interpretation in terms of differential genetic expression, to ...
... Description This package provides a multivariate inferential analysis method for detecting differentially expressed genes in gene expression data. It uses artificial components, close to the data's principal components but with an exact interpretation in terms of differential genetic expression, to ...