Molecular Dynamics of a Presynaptic Active Zone
... protein of interest with a fluorescent protein. We generated knock-in mice expressing a fusion protein of the presynaptic active zone protein Munc13-1 and enhanced yellow fluorescent protein (EYFP) from the Munc13-1 locus. Munc13-1–EYFP-containing nerve cells and synapses are functionally identical ...
... protein of interest with a fluorescent protein. We generated knock-in mice expressing a fusion protein of the presynaptic active zone protein Munc13-1 and enhanced yellow fluorescent protein (EYFP) from the Munc13-1 locus. Munc13-1–EYFP-containing nerve cells and synapses are functionally identical ...
Identification of alternative spliced mRNA variants related to(1).
... 35% splicing variants were detected exclusively in cancer tissues 29% were only detected in normal tissues This implies that new splicing variants might be generated during carcinogenesis This result supports the observation that during carcinogenesis not only is the expression profile affecte ...
... 35% splicing variants were detected exclusively in cancer tissues 29% were only detected in normal tissues This implies that new splicing variants might be generated during carcinogenesis This result supports the observation that during carcinogenesis not only is the expression profile affecte ...
Evolution on the X chromosome: unusual patterns and processes
... and are therefore not exposed to selection32. If they arise on the X (or Z) chromosome, however, their effect on fitness is fully expressed in the hemizygous males (or females). Therefore, selection is expected to fix beneficial recessive, or partially recessive, mutations (and remove deleterious re ...
... and are therefore not exposed to selection32. If they arise on the X (or Z) chromosome, however, their effect on fitness is fully expressed in the hemizygous males (or females). Therefore, selection is expected to fix beneficial recessive, or partially recessive, mutations (and remove deleterious re ...
Sleep wake cycle in a human being
... When humans are given light during the dark phase or in complete darkness when melatonin is high, melatonin levels in the blood quickly drop. This is even observed in some blind patients. ...
... When humans are given light during the dark phase or in complete darkness when melatonin is high, melatonin levels in the blood quickly drop. This is even observed in some blind patients. ...
entire lesson plan PDF
... This unit was designed utilizing themes in the Next Generation Science Standards as well as real world application to the agricultural industry. The lessons may be used independently or as a self-contained unit which covers in depth the concepts of genetics including an introduction to human inherit ...
... This unit was designed utilizing themes in the Next Generation Science Standards as well as real world application to the agricultural industry. The lessons may be used independently or as a self-contained unit which covers in depth the concepts of genetics including an introduction to human inherit ...
Chapter 1
... Occurs from two to eight weeks after conception Rate of cell differentiation intensifies Begins as the blastocyst attaches to the uterine wall ...
... Occurs from two to eight weeks after conception Rate of cell differentiation intensifies Begins as the blastocyst attaches to the uterine wall ...
ABO Antibodies
... Most severe form of HDN (Usually*) affects only 2nd or subsequent pregnancies (mother allo-immunized at delivery of 1st pregnancy; has pre-formed Abs during ...
... Most severe form of HDN (Usually*) affects only 2nd or subsequent pregnancies (mother allo-immunized at delivery of 1st pregnancy; has pre-formed Abs during ...
Discussion paper - Office of the Gene Technology Regulator
... The primary aim of this review is to provide clarity about whether organisms developed using a range of new technologies are subject to regulation as genetically modified organisms (GMOs) and ensure that new technologies are regulated in a manner commensurate with the risks they pose. The technical ...
... The primary aim of this review is to provide clarity about whether organisms developed using a range of new technologies are subject to regulation as genetically modified organisms (GMOs) and ensure that new technologies are regulated in a manner commensurate with the risks they pose. The technical ...
Mendelian Genetics and Chromosomes PPT
... whole, not a reductionist view of single genes acting in isolation ...
... whole, not a reductionist view of single genes acting in isolation ...
Products of the Ghrelin Gene, the Pancreatic β
... The survival and antiapoptotic effects of the ghrelin gene products have been described in a variety of cell types [43]. Interestingly, AG and UAG, when investigated together, showed similar ability to increase cell proliferation and survival and to inhibit apoptosis. Due to UAG inability to bind to ...
... The survival and antiapoptotic effects of the ghrelin gene products have been described in a variety of cell types [43]. Interestingly, AG and UAG, when investigated together, showed similar ability to increase cell proliferation and survival and to inhibit apoptosis. Due to UAG inability to bind to ...
Galactose Metabolism in Saccharomyces cerevisiae
... expression of the genes encoding the enzymes of the Leloir pathway (the GAL genes) was one of the first eukaryotic gene expression systems to be studied in any detail. Indeed, to this day, this still represents a genetically and biochemically amenable system for elucidating mechanisms of gene expres ...
... expression of the genes encoding the enzymes of the Leloir pathway (the GAL genes) was one of the first eukaryotic gene expression systems to be studied in any detail. Indeed, to this day, this still represents a genetically and biochemically amenable system for elucidating mechanisms of gene expres ...
Genetics Practice Problems**** Class Copy
... fluids as well as in the blood. The other 15% do not have blood type proteins in the saliva ("nonsecretors"). If secretor (S) is dominant to non-secretor (s) and this gene assorts independently of the A-B-O blood type gene, what proportion of the offspring from a mating between type AB, Ss with type ...
... fluids as well as in the blood. The other 15% do not have blood type proteins in the saliva ("nonsecretors"). If secretor (S) is dominant to non-secretor (s) and this gene assorts independently of the A-B-O blood type gene, what proportion of the offspring from a mating between type AB, Ss with type ...
Tracking bacterial DNA replication forks in vivo by pulsed field gel
... E. coli strain AQ2, derived from isolate 15, was pulse labeled with 14C-thymidine at various times during amino acid starvation and after the start of synchronous DNA synthesis. Intact chromosomal DNA was prepared in agarose and digested with the restriction enzyme Not I. The resulting Not I fragmen ...
... E. coli strain AQ2, derived from isolate 15, was pulse labeled with 14C-thymidine at various times during amino acid starvation and after the start of synchronous DNA synthesis. Intact chromosomal DNA was prepared in agarose and digested with the restriction enzyme Not I. The resulting Not I fragmen ...
Cancer Knudson`s —two-hit“ hypothesis
... the ability of cells to form a tumor is a recessive trait. They observed that the growth of murine tumor cells in syngeneic animals could be suppressed when the malignant cells were fused to nonmalignant cells, although reversion to tumorigenicity often occurred when the hybrids were propagated for ...
... the ability of cells to form a tumor is a recessive trait. They observed that the growth of murine tumor cells in syngeneic animals could be suppressed when the malignant cells were fused to nonmalignant cells, although reversion to tumorigenicity often occurred when the hybrids were propagated for ...
Traits and Families
... A gene is a recipe for a protein. It is used by the cell to make that protein. In achondroplasia, the normal allele (FGRF3) codes for a protein (fibroblast growth factor) that is part of the structure of normal bones, including those of the arms and legs. The achondroplasia allele produces a protein ...
... A gene is a recipe for a protein. It is used by the cell to make that protein. In achondroplasia, the normal allele (FGRF3) codes for a protein (fibroblast growth factor) that is part of the structure of normal bones, including those of the arms and legs. The achondroplasia allele produces a protein ...
Mendel’s Laws and Genetics Douglas Wilkin, Ph.D. Jean Brainard, Ph.D.
... Mendel used hundreds or even thousands of pea plants in each experiment he did. Therefore, his results were very close to those you would expect based on the rules of probability (see "Probability and Inheritance" concept). For example, in one of his first experiments with flower color, there were 9 ...
... Mendel used hundreds or even thousands of pea plants in each experiment he did. Therefore, his results were very close to those you would expect based on the rules of probability (see "Probability and Inheritance" concept). For example, in one of his first experiments with flower color, there were 9 ...
Bacterial genospecies that are not ecologically
... There is a prevalent view that we should not expect ‘good0 species in bacteria because even distantly related bacteria can share genes [2,3]. Nevertheless, it is undeniable that bacteria are not uniformly distributed across the potential ‘genomic space0 , but form clusters. It has been argued that b ...
... There is a prevalent view that we should not expect ‘good0 species in bacteria because even distantly related bacteria can share genes [2,3]. Nevertheless, it is undeniable that bacteria are not uniformly distributed across the potential ‘genomic space0 , but form clusters. It has been argued that b ...
Case study # 39 Keith Fehring, BA 2009 Andre Jakoi, BS 2008
... patient is homozygous of heterozygous for the abnormal FGFR3 gene. Currently, there is no cure or specific treatment for achondroplasia, but many treatments have been used with varied success. Pharmacologic, as well as surgical therapies are available if needed. It is important to monitor the pat ...
... patient is homozygous of heterozygous for the abnormal FGFR3 gene. Currently, there is no cure or specific treatment for achondroplasia, but many treatments have been used with varied success. Pharmacologic, as well as surgical therapies are available if needed. It is important to monitor the pat ...
- Wiley Online Library
... Griffith in 1928 (Griffith, 1928) when he studied the conditions responsible for acquisition of a capsule by unencapsulated strains of Streptococcus pneumoniae. The molecular basis of this phenomenon was not understood, however, before DNA was identified as the transforming agent by Avery and co-wor ...
... Griffith in 1928 (Griffith, 1928) when he studied the conditions responsible for acquisition of a capsule by unencapsulated strains of Streptococcus pneumoniae. The molecular basis of this phenomenon was not understood, however, before DNA was identified as the transforming agent by Avery and co-wor ...
The Chloroplast trnT–trnF Region in the Seed Plant
... that resembled the ‘‘)35’’ and ‘‘)10’’ promoter regions of bacterial genes, probably because of the bacterial origin of the chloroplast (see also HanleyBowdoin and Chua 1987; Bogorad 1991; Inokuchi and Yamao 1995). Analysis of these conserved regions together with ones seen in other plastid genes yi ...
... that resembled the ‘‘)35’’ and ‘‘)10’’ promoter regions of bacterial genes, probably because of the bacterial origin of the chloroplast (see also HanleyBowdoin and Chua 1987; Bogorad 1991; Inokuchi and Yamao 1995). Analysis of these conserved regions together with ones seen in other plastid genes yi ...
Insights into three whole-genome duplications gleaned
... lineage. Though large-scale synteny has broken down to an extent between P. caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10, ...
... lineage. Though large-scale synteny has broken down to an extent between P. caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10, ...
