Linkage disequilibrium mapping in trisomic populations: analytical approaches and an application to congenital heart defects in Down syndrome.
... variability suggests that it is allelic variation and not simply the presence of an additional chromosome that leads to the development of certain trisomy-associated birth defects. With the proper tools, one may use trisomic populations to identify genes involved in the development of specific birth ...
... variability suggests that it is allelic variation and not simply the presence of an additional chromosome that leads to the development of certain trisomy-associated birth defects. With the proper tools, one may use trisomic populations to identify genes involved in the development of specific birth ...
Journal of Microbiology and Biotechnology
... of nutritional value to humans, and also protect plants from oxidative stress. This study aimed to increase transgenic potatoes’ (Solanum tuberosum cv. LongShu No.3) tolerance to environmental stress and enhance their nutritional value. Transgenic potato plants expressing IbMYB1 genes under the cont ...
... of nutritional value to humans, and also protect plants from oxidative stress. This study aimed to increase transgenic potatoes’ (Solanum tuberosum cv. LongShu No.3) tolerance to environmental stress and enhance their nutritional value. Transgenic potato plants expressing IbMYB1 genes under the cont ...
McCarrison - Nutrition and National Health - Contents
... more general aspects of nutrition in relation to public health. But during the time that has elapsed since then I have seen, heard and read much both in the lay Press and elsewhere which leads me to believe that the significance of the term, 'nutrition', is not always fully understood. It has seemed ...
... more general aspects of nutrition in relation to public health. But during the time that has elapsed since then I have seen, heard and read much both in the lay Press and elsewhere which leads me to believe that the significance of the term, 'nutrition', is not always fully understood. It has seemed ...
The evolutionary mechanics of bacterial protein toxins
... When these factors are blocked, new proteins cannot be synthesized, which leads to cell death. Toxins in this group are responsible for diphtheria and bacilliary dysentery, and contribute to Pseudomonas aeruginosa infection. ...
... When these factors are blocked, new proteins cannot be synthesized, which leads to cell death. Toxins in this group are responsible for diphtheria and bacilliary dysentery, and contribute to Pseudomonas aeruginosa infection. ...
Sickle Cell Anemia Answer Key - Illuminations
... Sickle cell disease: a genetic disease Sickle trait: a genotype with one sickle and one normal gene. People with sickle trait are immune to malaria. Normal: a genotype that does not have any potential for passing on a sickle gene Allele: a gene from one parent. One gene from each parent combined mak ...
... Sickle cell disease: a genetic disease Sickle trait: a genotype with one sickle and one normal gene. People with sickle trait are immune to malaria. Normal: a genotype that does not have any potential for passing on a sickle gene Allele: a gene from one parent. One gene from each parent combined mak ...
Structure and function of nucleases in DNA repair: shape
... incision is performed by the UvrB-UvrC complex. In budding yeast, Rad2 and the Rad1-Rad10 complex make the 5’ and 3’ incisions, respectively. The same process in mammalian cells is conducted by their homologs, XPG and XPF-ERCC1, respectively. Deletions or mutations introduced into these nucleases ca ...
... incision is performed by the UvrB-UvrC complex. In budding yeast, Rad2 and the Rad1-Rad10 complex make the 5’ and 3’ incisions, respectively. The same process in mammalian cells is conducted by their homologs, XPG and XPF-ERCC1, respectively. Deletions or mutations introduced into these nucleases ca ...
The response regulator 2 mediates ethylene signalling and
... observed phenotype (Figure 1A). The incomplete complementation is very likely due to the 35S promoter, which may not perfectly establish the expression pattern of the native ARR2 promoter. The arr2 mutant phenotype was only observed in homozygous arr2 lines, indicating the recessive nature of the mu ...
... observed phenotype (Figure 1A). The incomplete complementation is very likely due to the 35S promoter, which may not perfectly establish the expression pattern of the native ARR2 promoter. The arr2 mutant phenotype was only observed in homozygous arr2 lines, indicating the recessive nature of the mu ...
Structural analysis of both products of a reciprocal translocation
... fragment 1n the cloned DNA that spans the J5 rearrangement s i t e , clearly demonstrating that the rearrangement found In cloned BL22 DNA 1s not a cloning a r t i f a c t . A schematic diagram of the reciprocal rearranged fragment and germline c-myc DNA 1s shown below the autoradiogram. The positio ...
... fragment 1n the cloned DNA that spans the J5 rearrangement s i t e , clearly demonstrating that the rearrangement found In cloned BL22 DNA 1s not a cloning a r t i f a c t . A schematic diagram of the reciprocal rearranged fragment and germline c-myc DNA 1s shown below the autoradiogram. The positio ...
Mapping avirulence genes in the rice blast fungus Magnaporthe grisea
... cultivar race specificity and its variability. Breeding for resistance has shown that a large number of rice cultivars have major genes conferring complete resistance towards specific races of the rice blast fungus (Ou 1985, Kiyosawa et al., 1986). This cultivar specificity is controlled on the path ...
... cultivar race specificity and its variability. Breeding for resistance has shown that a large number of rice cultivars have major genes conferring complete resistance towards specific races of the rice blast fungus (Ou 1985, Kiyosawa et al., 1986). This cultivar specificity is controlled on the path ...
genome - Sift Desk
... introns varied between different MYB genes, with a maximum intron number of 15 and a minimum of 0 (supplemental table S1). It was worth noting that a large number of 2R-MYB genes (60, 67%) have a conserved splicing pattern gene structure with three exons and two introns (Fig. 1). On the contrary, ge ...
... introns varied between different MYB genes, with a maximum intron number of 15 and a minimum of 0 (supplemental table S1). It was worth noting that a large number of 2R-MYB genes (60, 67%) have a conserved splicing pattern gene structure with three exons and two introns (Fig. 1). On the contrary, ge ...
Department of Biomedical Informatics
... (SNP) The single nucleotide polymorphism (SNP) [pronounced "snip"] is the most common form of genetic variation. As the name suggests, each SNP is a difference in a single nucleotide (A,T,C,or G) of an individual's DNA sequence, such as having AAGG instead of ATGG. There may be from 1 to 10 million ...
... (SNP) The single nucleotide polymorphism (SNP) [pronounced "snip"] is the most common form of genetic variation. As the name suggests, each SNP is a difference in a single nucleotide (A,T,C,or G) of an individual's DNA sequence, such as having AAGG instead of ATGG. There may be from 1 to 10 million ...
Phenylketonuria (PKU)
... certain foods to eat is because it has the protein we cannot take in. The protein that we cannot take in is “backed up” in the body and the brain just gets overwhelmed with protein chemicals, and starts to shut down on various parts of the brain. Don’t worry, it doesn’t shut down the part that contr ...
... certain foods to eat is because it has the protein we cannot take in. The protein that we cannot take in is “backed up” in the body and the brain just gets overwhelmed with protein chemicals, and starts to shut down on various parts of the brain. Don’t worry, it doesn’t shut down the part that contr ...
Chapter 21
... Each family of transposons in maize has both autonomous and nonautonomous controlling elements. Autonomous controlling elements code for proteins that enable them to transpose. Nonautonomous controlling elements have mutations that eliminate their capacity to catalyze transposition, but they can tra ...
... Each family of transposons in maize has both autonomous and nonautonomous controlling elements. Autonomous controlling elements code for proteins that enable them to transpose. Nonautonomous controlling elements have mutations that eliminate their capacity to catalyze transposition, but they can tra ...
Package `rDNA`
... This method computes the density of network matrices. It works for weighted or binary networks, and it can return within- and between-block density if actor types or the affiliation of actors to theoretical groups is given. For example, in a network of political actors, each actor may have a certain ...
... This method computes the density of network matrices. It works for weighted or binary networks, and it can return within- and between-block density if actor types or the affiliation of actors to theoretical groups is given. For example, in a network of political actors, each actor may have a certain ...
lecture - Department of Molecular & Cell Biology
... the ability of cells to form a tumor is a recessive trait. They observed that the growth of murine tumor cells in syngeneic animals could be suppressed when the malignant cells were fused to nonmalignant cells, although reversion to tumorigenicity often occurred when the hybrids were propagated for ...
... the ability of cells to form a tumor is a recessive trait. They observed that the growth of murine tumor cells in syngeneic animals could be suppressed when the malignant cells were fused to nonmalignant cells, although reversion to tumorigenicity often occurred when the hybrids were propagated for ...
Genetic Dissection of Complex Traits
... the 3-globin locus can show markedly different clinical courses, ranging from early childhood mortality to a virtually unrecognized condition at age 50 (6). The trait of severe sickle cell anemia is thus complex, being influenced by multiple genetic factors including a mapped X-linked locus and an i ...
... the 3-globin locus can show markedly different clinical courses, ranging from early childhood mortality to a virtually unrecognized condition at age 50 (6). The trait of severe sickle cell anemia is thus complex, being influenced by multiple genetic factors including a mapped X-linked locus and an i ...
Phenotypic and Genotypic Characterization S Sellers, B Gandolfi
... established into a recognized breed, called Munchkin, in 1994 (1). To date, the Munchkin breed has not been fully clinically and genetically characterized (Figure 1). In human achondroplasia, a mutation in the FGFR3 gene, is the most common form of human dwarfism that occurs 1 in 15,000 live births ...
... established into a recognized breed, called Munchkin, in 1994 (1). To date, the Munchkin breed has not been fully clinically and genetically characterized (Figure 1). In human achondroplasia, a mutation in the FGFR3 gene, is the most common form of human dwarfism that occurs 1 in 15,000 live births ...
The past, present and future of plant breeding
... useful traits that had appeared spontaneously were bred into certain crops by human selection, often by going against natural selection. Mendel’s discovery of the laws of inheritance towards the end of the 19th century accelerated plant modification. With the discovery of the structure of DNA by Wat ...
... useful traits that had appeared spontaneously were bred into certain crops by human selection, often by going against natural selection. Mendel’s discovery of the laws of inheritance towards the end of the 19th century accelerated plant modification. With the discovery of the structure of DNA by Wat ...
1 Rapid evolution of phenotypic plasticity and shifting thresholds of
... Although there has been renewed interest in the evolution of phenotypic plasticity and its importance for affecting the rate and direction of evolution of populations experiencing novel environments (reviewed in Matesanz et al. 2010; Pfennig et al. 2010; Moczek et al. 2011), it is still unclear how ...
... Although there has been renewed interest in the evolution of phenotypic plasticity and its importance for affecting the rate and direction of evolution of populations experiencing novel environments (reviewed in Matesanz et al. 2010; Pfennig et al. 2010; Moczek et al. 2011), it is still unclear how ...
genomic flux: genome evolution by gene loss and
... information changes over time. This process involves four sorts of changes: (i) point mutations and gene conversion events gradually alter internal information; (ii) rearrangements (e.g., inversions, translocations, plasmid integration, and transpositions) alter chromosome topology with little chang ...
... information changes over time. This process involves four sorts of changes: (i) point mutations and gene conversion events gradually alter internal information; (ii) rearrangements (e.g., inversions, translocations, plasmid integration, and transpositions) alter chromosome topology with little chang ...
misinformation, misrepresentation, and misuse of human behavioral
... involved in the production of two (or more) different proteins as the two different messenger-RNA (mRNA) strands are produced from overlapping parts of that stretch of DNA. (3) Overlapping Genes. In the case of so-called overlapping genes, one continuous stretch of DNA is involved in the production ...
... involved in the production of two (or more) different proteins as the two different messenger-RNA (mRNA) strands are produced from overlapping parts of that stretch of DNA. (3) Overlapping Genes. In the case of so-called overlapping genes, one continuous stretch of DNA is involved in the production ...