Regulation of limb bud initiation and limbtype
... and although npnt is ubiquitously expressed during frog development at the time forelimb outgrowth is initiated, transcripts are enriched in pronephros. The correlation with pronephros is potentially significant since extirpation experiments in the chick have implicated nephrogenic mesoderm in foreli ...
... and although npnt is ubiquitously expressed during frog development at the time forelimb outgrowth is initiated, transcripts are enriched in pronephros. The correlation with pronephros is potentially significant since extirpation experiments in the chick have implicated nephrogenic mesoderm in foreli ...
Randa Elfadil Ibrahim abdalla
... research for the financial support. To all those who encouraged me, I owe and gladly acknowledge a considerable debt. Finally, I would like to acknowledge and thank The National Ribat University. Abstract Introduction: Asthma is an inflammatory disease that results from interactions between multiple ...
... research for the financial support. To all those who encouraged me, I owe and gladly acknowledge a considerable debt. Finally, I would like to acknowledge and thank The National Ribat University. Abstract Introduction: Asthma is an inflammatory disease that results from interactions between multiple ...
The landscape of Neandertal ancestry in present
... We have shown that interbreeding of Neandertals and modern humans introduced alleles onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively larg ...
... We have shown that interbreeding of Neandertals and modern humans introduced alleles onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively larg ...
ARTICLES
... 40 times more frequently than the wild-type pair. Taken together with other biochemical data, it was postulated that such mutations possibly alter the angle of the junction of the anticodon stem and the central tRNA L-shaped structure, increasing the frequency of wobble reading10. Some bases in tRNA ...
... 40 times more frequently than the wild-type pair. Taken together with other biochemical data, it was postulated that such mutations possibly alter the angle of the junction of the anticodon stem and the central tRNA L-shaped structure, increasing the frequency of wobble reading10. Some bases in tRNA ...
Polyploidy
... • Understand the differences between ‘Interference’, and the suppression of recombination resulting from inversions, • Be able to recognize data, and predict results given either case. ...
... • Understand the differences between ‘Interference’, and the suppression of recombination resulting from inversions, • Be able to recognize data, and predict results given either case. ...
Metatranscriptome_Pipeline_Tutorial.doc
... We are currently working on a single script to run the entire process taking fastq sequence files generated by the sequencer to files that can be read by the visualization tool, here we illustrate the use of the pipeline by going through the various steps to illustrate the complexity of the process ...
... We are currently working on a single script to run the entire process taking fastq sequence files generated by the sequencer to files that can be read by the visualization tool, here we illustrate the use of the pipeline by going through the various steps to illustrate the complexity of the process ...
The C-terminal domain of the Rhizobium leguminosarum
... pIJ1887 containing TnphoA were transferred to R. leguminosarum strain 8401 by conjugation. NodC–PhoA fusions expressing high levels of alkaline phosphatase could be identified in R. leguminosarum on plates containing hesperetin to induce nod gene expression and the chromogenic indicator 5'-bromo-4'- ...
... pIJ1887 containing TnphoA were transferred to R. leguminosarum strain 8401 by conjugation. NodC–PhoA fusions expressing high levels of alkaline phosphatase could be identified in R. leguminosarum on plates containing hesperetin to induce nod gene expression and the chromogenic indicator 5'-bromo-4'- ...
Practice Genetic Problems PMB 220 1. In working with a haploid
... 3. In a haploid yeast, a cross between a strain requiring arginine (arg-), adenine(ad-), but not nicotinic acid (nic+) or leucine (leu+) and a strain that does not require arginine (arg+) or adenine (ad+), but which does require nicotinamide (nic-) and leucine (leu-) produced sexual spores and 20 of ...
... 3. In a haploid yeast, a cross between a strain requiring arginine (arg-), adenine(ad-), but not nicotinic acid (nic+) or leucine (leu+) and a strain that does not require arginine (arg+) or adenine (ad+), but which does require nicotinamide (nic-) and leucine (leu-) produced sexual spores and 20 of ...
GENETICS DEFINITION
... an a gamete is ½ each. Likewise for the second genotype. If an A sperm fertilized an A ovum, then the result would be an AA zygote. The probability of this occurring is ½ x ½ = ¼. The same would be true for an a sperm fertilizing an a ...
... an a gamete is ½ each. Likewise for the second genotype. If an A sperm fertilized an A ovum, then the result would be an AA zygote. The probability of this occurring is ½ x ½ = ¼. The same would be true for an a sperm fertilizing an a ...
Motoo Kimura and James Crow on the Infinitely Many Alleles Model
... Malécot’s result was relevant for a theoretical analysis of the reasons for this variation. They made the straightforward generalization of Malécot’s formula to (4Neu + 1)21, where Ne is the effective population size. [There are at least four concepts of effective population size (Ewens 2000); Kimur ...
... Malécot’s result was relevant for a theoretical analysis of the reasons for this variation. They made the straightforward generalization of Malécot’s formula to (4Neu + 1)21, where Ne is the effective population size. [There are at least four concepts of effective population size (Ewens 2000); Kimur ...
- UEA Digital Repository
... 2.19 Isotope pairing experiments for detection of denitrification and anammox .....65 Chapter 3. Isolation of methylated amine-utilising bacteria from Movile Cave ...67 ...
... 2.19 Isotope pairing experiments for detection of denitrification and anammox .....65 Chapter 3. Isolation of methylated amine-utilising bacteria from Movile Cave ...67 ...
Engrailed cooperates with extradenticle and homothorax to repress
... Like many eukaryotic DNA-binding proteins, the specificity of DNA binding by En alone appears to be lower than that required for highly selective interaction with specific target genes. This suggests that, like many other DNA binding proteins, En interacts with cofactors that increase its binding sp ...
... Like many eukaryotic DNA-binding proteins, the specificity of DNA binding by En alone appears to be lower than that required for highly selective interaction with specific target genes. This suggests that, like many other DNA binding proteins, En interacts with cofactors that increase its binding sp ...
Review of the p53 Tumor Suppressor Gene and its Role in Gliomas
... render them tumorigenic in vivo (Cantley et al., 1991; Bishop, 1991; Hunter, 1991). ...
... render them tumorigenic in vivo (Cantley et al., 1991; Bishop, 1991; Hunter, 1991). ...
The genetics of Caenorhabditis elegans.
... Hermaphrodite genetics: Self-fertilizing hermaphrodites have many advantages for genetical analysis. It is likely that the clones established in the laboratory are of uniform genetical constitution since the animals are driven to homozygosity. Recessive mutants are easily isolated on both the autoso ...
... Hermaphrodite genetics: Self-fertilizing hermaphrodites have many advantages for genetical analysis. It is likely that the clones established in the laboratory are of uniform genetical constitution since the animals are driven to homozygosity. Recessive mutants are easily isolated on both the autoso ...
Rhizobium Nodulation Protein NodC Is an Important Determinant of
... strains with R. meliloti and R. loti NodC, producing chitintetraose and chitinpentaose, respectively. In vitro experiments, using UDP-[14C]GlcNAc as a precursor, show that this difference reflects intrinsic properties of these NodC proteins and that it is not influenced by the UDP-GlcNAc concentrati ...
... strains with R. meliloti and R. loti NodC, producing chitintetraose and chitinpentaose, respectively. In vitro experiments, using UDP-[14C]GlcNAc as a precursor, show that this difference reflects intrinsic properties of these NodC proteins and that it is not influenced by the UDP-GlcNAc concentrati ...
Genetic analysis of root-knot nematode resistance in potato
... Because most of the 2n-pollen is generated via FDR, and because the selection for 2n-pollen is less laborious than the selection for 2n-eggs, the recovery of the tetraploid level is preferred by means of 4x.2x crosses. Besides the direct gene transfer and more efficient breeding, the use of diploid ...
... Because most of the 2n-pollen is generated via FDR, and because the selection for 2n-pollen is less laborious than the selection for 2n-eggs, the recovery of the tetraploid level is preferred by means of 4x.2x crosses. Besides the direct gene transfer and more efficient breeding, the use of diploid ...
Neurospora Spore Killers Sk-2 and Sk
... of the tetrad give rise to round ascospores; even those nuclei that contain a wild-type allele are round. The cause of dominance is probably rearrangements and/or deletions that prevent the wild-type allele from pairing with a homolog. MSUD is implicated in these ascusdominant phenotypes of these mu ...
... of the tetrad give rise to round ascospores; even those nuclei that contain a wild-type allele are round. The cause of dominance is probably rearrangements and/or deletions that prevent the wild-type allele from pairing with a homolog. MSUD is implicated in these ascusdominant phenotypes of these mu ...
ABO genotyping in leukemia patients reveals new ABO variant alleles
... The sequence of nucleotides comprising the ABO gene, its structure and some of its common variants were determined in the early 1990s (Yamamoto and Hakomori, 1990; Yamamoto et al., 1990a). This gene, mapped on chromosome 9q34.1-34.2, consists of 7 exons ranging from 28 to 688 bp. More than 90% of th ...
... The sequence of nucleotides comprising the ABO gene, its structure and some of its common variants were determined in the early 1990s (Yamamoto and Hakomori, 1990; Yamamoto et al., 1990a). This gene, mapped on chromosome 9q34.1-34.2, consists of 7 exons ranging from 28 to 688 bp. More than 90% of th ...
trigger - Bioconductor
... triggerobj <- trigger.mlink(triggerobj, B = 10, idx = NULL, seed = 123) plot(triggerobj, type = "trigger.mlink", qcut=0.1, bin.size=NULL) mlink = slot(triggerobj, "trigger.mlink") ...
... triggerobj <- trigger.mlink(triggerobj, B = 10, idx = NULL, seed = 123) plot(triggerobj, type = "trigger.mlink", qcut=0.1, bin.size=NULL) mlink = slot(triggerobj, "trigger.mlink") ...
- VU Research Repository
... One of the major yeast stressors during fermentation is ethanol accumulation. Ethanol stress is associated with reduced cell growth and viability, consequently lowering yeast productivity. Although the underlying causes of ethanol inhibition of cells are yet to be identified, it has been discovered ...
... One of the major yeast stressors during fermentation is ethanol accumulation. Ethanol stress is associated with reduced cell growth and viability, consequently lowering yeast productivity. Although the underlying causes of ethanol inhibition of cells are yet to be identified, it has been discovered ...
Diversity and origins of anaerobic metabolism in mitochondria and
... Mitochondria and related organelles are ubiquitous among eukaryotes. The last half-century of cellular and molecular evolutionary research has conclusively shown that mitochondria are descended from an a-proteobacterial endosymbiont that took up residence within a host cell prior to the last eukaryo ...
... Mitochondria and related organelles are ubiquitous among eukaryotes. The last half-century of cellular and molecular evolutionary research has conclusively shown that mitochondria are descended from an a-proteobacterial endosymbiont that took up residence within a host cell prior to the last eukaryo ...
Host Genetic Control of Incubation Periods of Creutzfeldt
... were obtained from Seiwa Experimental Animals, Yoshitomi, Japan, and SWR/J were from the Jackson Laboratory, Bar Harbor, Me., U.S.A. Mice were maintained in rooms with a controlled temperature (23 to 27 °C) and humidity (55 to 65 %), with a 12 h on and 12 h off cycleof artificial light. Food and wat ...
... were obtained from Seiwa Experimental Animals, Yoshitomi, Japan, and SWR/J were from the Jackson Laboratory, Bar Harbor, Me., U.S.A. Mice were maintained in rooms with a controlled temperature (23 to 27 °C) and humidity (55 to 65 %), with a 12 h on and 12 h off cycleof artificial light. Food and wat ...
Figures 1
... muscle mass and delay of fat tissue accumulation), body proportions, acquisition of gross motor skills, language acquisition, and cognitive scores.36–43 Older children and adolescents treated with GH therapy not only have the aforementioned physical benefits of the treatment but are also reported to ...
... muscle mass and delay of fat tissue accumulation), body proportions, acquisition of gross motor skills, language acquisition, and cognitive scores.36–43 Older children and adolescents treated with GH therapy not only have the aforementioned physical benefits of the treatment but are also reported to ...
PDF
... of the wild-type protein show normal induction of mesodermal marker genes, whereas knockout cells lacking Utx protein fail to induce expression of these genes (Wang et al., 2012). Together, these studies led to the suggestion that the Utx/Uty proteins, but not their H3-K27me3 demethylase activity, a ...
... of the wild-type protein show normal induction of mesodermal marker genes, whereas knockout cells lacking Utx protein fail to induce expression of these genes (Wang et al., 2012). Together, these studies led to the suggestion that the Utx/Uty proteins, but not their H3-K27me3 demethylase activity, a ...
Neisseria meningitidis: an overview of the carriage state
... morphism (PCR-RFLP) and sequencing of the genes encoding the PorA and PorB OMP, have been demonstrated to be more reliable than serological methods for typing of meningococcal strains (van der Ende et al., 2000; Zhu et al., 1995). PorA protein can be stable during chronic carriage of N. meningitidis ...
... morphism (PCR-RFLP) and sequencing of the genes encoding the PorA and PorB OMP, have been demonstrated to be more reliable than serological methods for typing of meningococcal strains (van der Ende et al., 2000; Zhu et al., 1995). PorA protein can be stable during chronic carriage of N. meningitidis ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.