Abstracts - Parthenon Management Group
... each making a small contribution to risk of the disorder, and it also clear from multi-locus tests that perhaps a thousand or more such risk variants exist. There is also substantially evidence that these common variants overlap with those that confer risk for bipolar disorder, and emerging evidence ...
... each making a small contribution to risk of the disorder, and it also clear from multi-locus tests that perhaps a thousand or more such risk variants exist. There is also substantially evidence that these common variants overlap with those that confer risk for bipolar disorder, and emerging evidence ...
GENETIC AND MOLECULAR ANALYSIS OF THE garnet EYE
... Although any work of science depends on the prior work of others, the specific contributions of some must be mentioned. The garnet gene was cloned by Dr. D. Sinclair, working in the laboratory of Dr. G. Tener, biochemistry U.B.C. Dr. Sinclair initiated the molecular analysis of the garnet gene, brou ...
... Although any work of science depends on the prior work of others, the specific contributions of some must be mentioned. The garnet gene was cloned by Dr. D. Sinclair, working in the laboratory of Dr. G. Tener, biochemistry U.B.C. Dr. Sinclair initiated the molecular analysis of the garnet gene, brou ...
univERsity oF copEnhAGEn
... genes. In a comparative study, we have directly tested two plant biosynthetic pathways for association between polymorphisms controlling biosynthetic gene transcripts and the resulting metabolites within the Arabidopsis Bay 3 Sha recombinant inbred line population. In this analysis, all loci control ...
... genes. In a comparative study, we have directly tested two plant biosynthetic pathways for association between polymorphisms controlling biosynthetic gene transcripts and the resulting metabolites within the Arabidopsis Bay 3 Sha recombinant inbred line population. In this analysis, all loci control ...
Functional Analysis of Maize RAD51 in Meiosis and
... same size between rad51A2-98E7 and the derivative allele. In contrast, if an allele arose via an intragenic transposition, the PCR product from the other side of the Mu insertion would be larger than the PCR product obtained from rad51A2-98E7. To differentiate between the insertion of an additional ...
... same size between rad51A2-98E7 and the derivative allele. In contrast, if an allele arose via an intragenic transposition, the PCR product from the other side of the Mu insertion would be larger than the PCR product obtained from rad51A2-98E7. To differentiate between the insertion of an additional ...
18. The Reference Sequence (RefSeq) Project
... more consistent format. LocusLink descriptive information including official nomenclature, alias symbols, alternate descriptive names, map location, and additional citations are applied to the records. Records at this stage have a PROVISIONAL, PREDICTED, or INFERRED status. These initial records the ...
... more consistent format. LocusLink descriptive information including official nomenclature, alias symbols, alternate descriptive names, map location, and additional citations are applied to the records. Records at this stage have a PROVISIONAL, PREDICTED, or INFERRED status. These initial records the ...
Different susceptibility of two animal species infected with isogenic
... D. M. Collins and others assessment of virulence in early work was based on the presence of visible lesions of tuberculosis in the spleen and, in later comparative work, on the enumeration of M. bovis c.f.u. in samples from the spleen. All animals were tested for infection by determining their dela ...
... D. M. Collins and others assessment of virulence in early work was based on the presence of visible lesions of tuberculosis in the spleen and, in later comparative work, on the enumeration of M. bovis c.f.u. in samples from the spleen. All animals were tested for infection by determining their dela ...
Investigating the functional significance of evolutionarily conserved
... Bilaterans share a common anterior-posterior (A-P) axis that is patterned by the Homeotic selector (Hox) genes. In Drosophila melanogaster, Hox gene expression in spatially restricted domains along the A-P axis of the embryo determines segmental identity. Identifying the genetic mechanisms of HOX co ...
... Bilaterans share a common anterior-posterior (A-P) axis that is patterned by the Homeotic selector (Hox) genes. In Drosophila melanogaster, Hox gene expression in spatially restricted domains along the A-P axis of the embryo determines segmental identity. Identifying the genetic mechanisms of HOX co ...
The obstruction of adaptation in diploids by recessive deleterious
... n diploids, the fitness effect of having a single copy of a mutation depends not only on the mutation’s selective effect, s, but also on its heterozygous effect, h. A fully recessive mutation (h = 0) is hidden in the heterozygote (hs = 0), and a fully dominant mutation (h = 1) is completely exposed ...
... n diploids, the fitness effect of having a single copy of a mutation depends not only on the mutation’s selective effect, s, but also on its heterozygous effect, h. A fully recessive mutation (h = 0) is hidden in the heterozygote (hs = 0), and a fully dominant mutation (h = 1) is completely exposed ...
Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
Desert hedgehogis a mammal-specific gene expressed during
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
... patched (PTCH) receptors and smoothened (SMO) protein [17]. Both proteins have orthologues in Drosophila that are also involved in hedgehog signal transduction and pattern formation. Initially, all three hedgehog protein functions were thought to be mediated through the PTCH1 receptor in mammals. Ho ...
Concentrations of the atherogenic Lp(a) are elevated in FH
... information for both the LDLR and the apo(a) gene. We analysed 367 family members of 30 South African and 30 French Canadian index patients with FH for LDLR mutations and for apo(a) genotype. Three lines of evidence showed a significant effect of FH on Lp(a) levels: (1) Lp(a) values were significant ...
... information for both the LDLR and the apo(a) gene. We analysed 367 family members of 30 South African and 30 French Canadian index patients with FH for LDLR mutations and for apo(a) genotype. Three lines of evidence showed a significant effect of FH on Lp(a) levels: (1) Lp(a) values were significant ...
Daniël van Draanen - Utrecht University Repository
... traits is limited to outer visible traits like eye colour, hair colour and skin texture (WoodRobinson, Lewis, & Leach, 2000). Further findings about educational use of the terms are discussed in paragraph 3.5 of the theoretical basis. According to concept learning theories, students have a prototyp ...
... traits is limited to outer visible traits like eye colour, hair colour and skin texture (WoodRobinson, Lewis, & Leach, 2000). Further findings about educational use of the terms are discussed in paragraph 3.5 of the theoretical basis. According to concept learning theories, students have a prototyp ...
Understanding Reads in RNA-Seq Analysis
... A read will be assigned to a transcript only when it is compatible. A compatible read is a read that fits the transcript model from the chosen annotation database. Compatible reads must be an exonic read (fully mapped to exon); however not all the exonic reads are compatible with a transcript, e.g., ...
... A read will be assigned to a transcript only when it is compatible. A compatible read is a read that fits the transcript model from the chosen annotation database. Compatible reads must be an exonic read (fully mapped to exon); however not all the exonic reads are compatible with a transcript, e.g., ...
PDF
... Organs are assemblies of differentiated cells, arranged into distinct configurations that allow them to carry out specialised functions. Specific tasks carried out by a particular organ are emergent properties that result from the coordinated interplay of the different specialised cell types they co ...
... Organs are assemblies of differentiated cells, arranged into distinct configurations that allow them to carry out specialised functions. Specific tasks carried out by a particular organ are emergent properties that result from the coordinated interplay of the different specialised cell types they co ...
Defining characteristics of Tn5 Transposase non
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
The Deletion Stocks of Common Wheat
... Chromosomal breaks occurred in the progeny of a common wheat (Tritlcum aestlvum L. em Thell; 2n = 6x = 42, genome formula AABBDD) cultivar Chinese Spring with a monosomic addition of an alien chromosome from Aegllops cyllndrlca Host (2n = 4x = 28, CCDD) or A. trlunclalls L. (2n = 4x = 28, UUCC) or a ...
... Chromosomal breaks occurred in the progeny of a common wheat (Tritlcum aestlvum L. em Thell; 2n = 6x = 42, genome formula AABBDD) cultivar Chinese Spring with a monosomic addition of an alien chromosome from Aegllops cyllndrlca Host (2n = 4x = 28, CCDD) or A. trlunclalls L. (2n = 4x = 28, UUCC) or a ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
... the most economically important plant diseases that are caused by phytoplasmas. Phylogenetic analyses revealed that the 16S rDNA sequences of strains of each of these pathogens were identical or nearly identical. Differences between the three phytoplasmas ranged from 1?0 to 1?5 % of nucleotide posit ...
... the most economically important plant diseases that are caused by phytoplasmas. Phylogenetic analyses revealed that the 16S rDNA sequences of strains of each of these pathogens were identical or nearly identical. Differences between the three phytoplasmas ranged from 1?0 to 1?5 % of nucleotide posit ...
Identification of genes that interact with glp-1, a gene
... abbreviation (e.g. Dpy for a dumpy phenotype) and genes are designated by a lower case, italicized abbreviation (e.g. dpy for dumpy genes). Where appropriate, abbreviations are placed after an allele number to indicate that it is temperature sensitive (ts), amber (am), or semidominant (sd). For each ...
... abbreviation (e.g. Dpy for a dumpy phenotype) and genes are designated by a lower case, italicized abbreviation (e.g. dpy for dumpy genes). Where appropriate, abbreviations are placed after an allele number to indicate that it is temperature sensitive (ts), amber (am), or semidominant (sd). For each ...
1999 Dekkers: BREEDING IN THE 21st CENTURY
... collective effect of polygenes. Kennedy et al (1992) suggested inclusion of genotype as a fixed effect in an animal model to estimate the effects of known genes, capitalizing on population-wide disequilibrium. Fernando and Grossman (1989) developed BLUP-QTL models for QTL linked to markers, relying ...
... collective effect of polygenes. Kennedy et al (1992) suggested inclusion of genotype as a fixed effect in an animal model to estimate the effects of known genes, capitalizing on population-wide disequilibrium. Fernando and Grossman (1989) developed BLUP-QTL models for QTL linked to markers, relying ...
get Assignment File
... 1. The principles of probability can be used to a. predict the traits of the offspring of genetic crosses. b. determine the actual outcomes of genetic crosses. c. determine which species should be used in genetic crosses. d. decide which organisms are best to use in genetic crosses. ...
... 1. The principles of probability can be used to a. predict the traits of the offspring of genetic crosses. b. determine the actual outcomes of genetic crosses. c. determine which species should be used in genetic crosses. d. decide which organisms are best to use in genetic crosses. ...
Osmoadaptation mechanisms in prokaryotes
... Summary. Microorganisms respond to osmotic stress mostly by accumulating compatible solutes, either by uptake from the medium or by de novo synthesis. These osmotically active molecules preserve the positive turgor pressure required for cell division. The diversity of compatible solutes is large but ...
... Summary. Microorganisms respond to osmotic stress mostly by accumulating compatible solutes, either by uptake from the medium or by de novo synthesis. These osmotically active molecules preserve the positive turgor pressure required for cell division. The diversity of compatible solutes is large but ...
A E M , Feb. 2004, p. 999–1007
... incorporated into the polymer. Short-chain-length (SCL) PHAs consist of monomer units of C3 to C5, mediumchain-length (MCL) PHAs consist of monomer units of C6 to C14, and SCL-MCL PHAs consist of monomers ranging in size from C4 to C14. Although previous studies using recombinant Escherichia coli ha ...
... incorporated into the polymer. Short-chain-length (SCL) PHAs consist of monomer units of C3 to C5, mediumchain-length (MCL) PHAs consist of monomer units of C6 to C14, and SCL-MCL PHAs consist of monomers ranging in size from C4 to C14. Although previous studies using recombinant Escherichia coli ha ...
1 FRQ-interacting RNA Helicase (FRH) Mediates Negative and
... SNP6 and SNP72 and were scored among those recombinant progeny. Using these additional markers, Mut10 was mapped in a 20kb region; the two ‘aberrant’ progeny also showed recombination with all newly identified markers, supporting the idea of a chromosomal translocation tightly associated with arrhyt ...
... SNP6 and SNP72 and were scored among those recombinant progeny. Using these additional markers, Mut10 was mapped in a 20kb region; the two ‘aberrant’ progeny also showed recombination with all newly identified markers, supporting the idea of a chromosomal translocation tightly associated with arrhyt ...
Virulence factors of Salmonella enterica serovar Enteritidis
... phage typing, biotyping, determination of antibiotic resistance patterns or plasmid profile analysis are used to identify isolates beyond the level of serovars and are valuable additional tools in epidemiological studies (4). Genetic analysis of Salmonella serovars indicates that their divergence in ...
... phage typing, biotyping, determination of antibiotic resistance patterns or plasmid profile analysis are used to identify isolates beyond the level of serovars and are valuable additional tools in epidemiological studies (4). Genetic analysis of Salmonella serovars indicates that their divergence in ...
The American University in Cairo School of Science and Engineering
... 7KH6+9ȕ-lactamase family originally was found in Klebsiella spp.. The progenitor of the SHV family, SHV-1, is universally present in K. pneumoniae. It has been shown that in most K. pneumoniae strains, the SHV-1 gene can be found on the bacterial chromosome, which may suggest that this gene may ha ...
... 7KH6+9ȕ-lactamase family originally was found in Klebsiella spp.. The progenitor of the SHV family, SHV-1, is universally present in K. pneumoniae. It has been shown that in most K. pneumoniae strains, the SHV-1 gene can be found on the bacterial chromosome, which may suggest that this gene may ha ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.