GeneCensus - Gerstein Lab Publications
... Both of these views are linked to additional modules representing more traditional analysis formats. These include modules that examine open reading frames (ORFs), organisms, and various compositions of genomes. In general, it is relatively difficult to integrate disparate information sources into o ...
... Both of these views are linked to additional modules representing more traditional analysis formats. These include modules that examine open reading frames (ORFs), organisms, and various compositions of genomes. In general, it is relatively difficult to integrate disparate information sources into o ...
Specific Combinations of Zein Genes and Genetic Backgrounds
... In the case of Bo2It, the mutant line from which the o2-Italian allele has been recovered and first described in the sixties (Nelson, 1967), a proper comparison is not possible because its O2 isogenic line is not available in any collection. The two GBs, W22 and Oh43, carrying the o2-676 allele (Auk ...
... In the case of Bo2It, the mutant line from which the o2-Italian allele has been recovered and first described in the sixties (Nelson, 1967), a proper comparison is not possible because its O2 isogenic line is not available in any collection. The two GBs, W22 and Oh43, carrying the o2-676 allele (Auk ...
thalassaemia mutations in Sardinians
... monitored by fetal blood analysis.5 In order to extend prenatal diagnosis by DNA analysis to carriers of the less frequent mutations, in the present study we investigated the molecular basis of 13 thalassaemia in a group of 13 thalassaemia chromosomes from Sardinians in whom we excluded the presence ...
... monitored by fetal blood analysis.5 In order to extend prenatal diagnosis by DNA analysis to carriers of the less frequent mutations, in the present study we investigated the molecular basis of 13 thalassaemia in a group of 13 thalassaemia chromosomes from Sardinians in whom we excluded the presence ...
Vertebrate genomics : More fishy tales about Hox genes
... — both land vertebrates and fishes — all have four homologous Hox clusters [4,7] has also been challenged [8,9]. Prince et al. [8] recently described 42 Hox genes from the zebrafish and suggested that they are arranged in six, rather than the expected four, clusters. Apparently, in the evolutionary ...
... — both land vertebrates and fishes — all have four homologous Hox clusters [4,7] has also been challenged [8,9]. Prince et al. [8] recently described 42 Hox genes from the zebrafish and suggested that they are arranged in six, rather than the expected four, clusters. Apparently, in the evolutionary ...
Answer Key for Midterm1
... Karen is a carrier of a recessive mutation in keritinosin, an X-linked gene. Loss of keritinosin function causes keritinosis. The symptoms included poor teeth, skin thickening, and defective sweat gland formation, especially on the hands and feet. A centromeric gene encoding an enzyme with several a ...
... Karen is a carrier of a recessive mutation in keritinosin, an X-linked gene. Loss of keritinosin function causes keritinosis. The symptoms included poor teeth, skin thickening, and defective sweat gland formation, especially on the hands and feet. A centromeric gene encoding an enzyme with several a ...
Bewildering Bs: an impression of the 1st B-Chromosome
... of each of these processes. In summary, Bs may be absent from a certain population because it is beyond the limit of the species' ecological tolerance for B chromosomes and/or because Bs have not reached this locality from their centre of origin. Another intriguing point that was raised is why are t ...
... of each of these processes. In summary, Bs may be absent from a certain population because it is beyond the limit of the species' ecological tolerance for B chromosomes and/or because Bs have not reached this locality from their centre of origin. Another intriguing point that was raised is why are t ...
Phytozome Tutorial from David Goodstein
... genes for 18 plant genomes (in version 5). Sequence similarity (BLAST/BLAT) and keywordbased searching can help you pinpoint genes and gene families of interest. You can navigate the evolutionary history of each gene family, and identify closely related families (via shared functional annotation or ...
... genes for 18 plant genomes (in version 5). Sequence similarity (BLAST/BLAT) and keywordbased searching can help you pinpoint genes and gene families of interest. You can navigate the evolutionary history of each gene family, and identify closely related families (via shared functional annotation or ...
Genome demethylation and imprinting in the endosperm
... mature embryo, and the endosperm. The endosperm, which serves as a conduit to store and transport nutrients to the embryo during initial phases of seed growth, is a major food source for most of the world. With one exception [1], all known plant gene imprinting occurs in the endosperm. Hence, this ...
... mature embryo, and the endosperm. The endosperm, which serves as a conduit to store and transport nutrients to the embryo during initial phases of seed growth, is a major food source for most of the world. With one exception [1], all known plant gene imprinting occurs in the endosperm. Hence, this ...
WNT targets - Stanford University
... components1; gene-specific repressors bind to regulatory sequences and repress gene expression by interacting with components of the transcriptional machinery. When cells enter a developmental program and start to express specific genes, repression is relieved. At a global level, chromatin undergoes ...
... components1; gene-specific repressors bind to regulatory sequences and repress gene expression by interacting with components of the transcriptional machinery. When cells enter a developmental program and start to express specific genes, repression is relieved. At a global level, chromatin undergoes ...
Review #3 - California Lutheran University
... What is the structure of tRNA? What is its tertiary structure? What are aminoacyl tRNA synthetases? What are the two classes of synthetases and how do they differ? If there are 61 codons and 32 or more tRNAs, why are there only 20 synthetases? What parts of the tRNA do the synthetases recognize? Why ...
... What is the structure of tRNA? What is its tertiary structure? What are aminoacyl tRNA synthetases? What are the two classes of synthetases and how do they differ? If there are 61 codons and 32 or more tRNAs, why are there only 20 synthetases? What parts of the tRNA do the synthetases recognize? Why ...
Mitochondrial genes in the colourless alga Prototheca wickerhamii
... introns in various strains of the yeast Saccharomyces cerevisiae, but none in the common laboratory strain of Neurospora crassa (5, 6, 7, 8). So far, only few introns have been detected in mitochondria from angiosperms and gymnosperms and all belong to group n (9, 10, 11). However, numerous group I ...
... introns in various strains of the yeast Saccharomyces cerevisiae, but none in the common laboratory strain of Neurospora crassa (5, 6, 7, 8). So far, only few introns have been detected in mitochondria from angiosperms and gymnosperms and all belong to group n (9, 10, 11). However, numerous group I ...
A novel frameshift mutation of HEXA gene in the
... and HEXB genes, respectively. TSD is caused by mutations in the HEXA gene (MIM*606869) located on chromosome 15q23-q24.1,2 The HEXA gene consists of 14 exons and contains 1,587 bp of coding sequence encoding a 529 amino acid protein. More than 130 mutations have been identified in the HEXA gene data ...
... and HEXB genes, respectively. TSD is caused by mutations in the HEXA gene (MIM*606869) located on chromosome 15q23-q24.1,2 The HEXA gene consists of 14 exons and contains 1,587 bp of coding sequence encoding a 529 amino acid protein. More than 130 mutations have been identified in the HEXA gene data ...
From DNA to Disorder - Liberty Union High School District
... Such parents have a low probability of having another child with achondroplasia. An individual with achondroplasia who has a partner with normal stature has a 50% probability in each pregnancy of having a child with achondroplasia. When both parents have achondroplasia, the probability of their offs ...
... Such parents have a low probability of having another child with achondroplasia. An individual with achondroplasia who has a partner with normal stature has a 50% probability in each pregnancy of having a child with achondroplasia. When both parents have achondroplasia, the probability of their offs ...
(FA-SAT) in a Cat Fibrosarcoma Might Be Related to Chromosomal
... numerical chromosomal alterations. Further segmental chromosomal gains and losses come from structural chromosomal alterations, including reciprocal and nonreciprocal translocations, homogeneously staining regions, amplifications, insertions, and deletions. Structural alterations may result in a fur ...
... numerical chromosomal alterations. Further segmental chromosomal gains and losses come from structural chromosomal alterations, including reciprocal and nonreciprocal translocations, homogeneously staining regions, amplifications, insertions, and deletions. Structural alterations may result in a fur ...
Chapter 14 – Mendel and the Gene Idea
... He studied at the University of Vienna from 1851 to 1853, where he was influenced by a physicist who encouraged experimentation and the application of mathematics to science and by a botanist who stimulated Mendel’s interest in the causes of variation in ...
... He studied at the University of Vienna from 1851 to 1853, where he was influenced by a physicist who encouraged experimentation and the application of mathematics to science and by a botanist who stimulated Mendel’s interest in the causes of variation in ...
The Ethics of Genes Therapy - People
... them the brightest, healthiest, and most advantaged children possible? Those people that lacked the financial capital or influence would be deemed inferior, and subjected to the discrimination of those possessing “superior” genes. Considering the entirety of germline gene therapy, such means are dif ...
... them the brightest, healthiest, and most advantaged children possible? Those people that lacked the financial capital or influence would be deemed inferior, and subjected to the discrimination of those possessing “superior” genes. Considering the entirety of germline gene therapy, such means are dif ...
Strategies for the molecular genetic manipulation and visualization of the... Penicillium marneffei
... riboswitches, small RNA elements that bind thiamine pyrophosphate to regulate the expression of genes required for the biosynthesis and transport of thiamine, an essential cofactor (Sudarsan et al. 2005). Pyrithiamine resistance can also be utilized as a dominant selectable marker for transformatio ...
... riboswitches, small RNA elements that bind thiamine pyrophosphate to regulate the expression of genes required for the biosynthesis and transport of thiamine, an essential cofactor (Sudarsan et al. 2005). Pyrithiamine resistance can also be utilized as a dominant selectable marker for transformatio ...
Targets for breast cancer diagnosis and treatment
... tained in a polynucleotide selected from the group consisting involves cDNA from only two cell populations at a time. it of CHl-9a1l-2. CH8-2a13-1. CHl3-2a12-l. and CH14 is sensitive to individual phenotypic variation. 2a16-1. Preferably. said RNA is overabundant in a propor Alternatively. expressio ...
... tained in a polynucleotide selected from the group consisting involves cDNA from only two cell populations at a time. it of CHl-9a1l-2. CH8-2a13-1. CHl3-2a12-l. and CH14 is sensitive to individual phenotypic variation. 2a16-1. Preferably. said RNA is overabundant in a propor Alternatively. expressio ...
... injected must match the mature “trimmed” mRNA sequence for the gene and the interference could not be elicited by intron sequences. This implies that interference takes place after transcription, probably in the cytoplasm rather than in the cell nucleus (4) The mRNA was revealed to be targeted with ...
Leukaemia Section t(1;14)(q21;q32) MUC1/IGH Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Located 8cM telomeric to BCL9; aliases of MUC1 are EMA and CD227. DNA/RNA 3.88 kb, 8 exons, 1721 bp, 2 transcripts. Protein 122.1 kDa (1255 aa) Highly glycosylated protein. The MUC1 protein can be expressed as a transmembrane or secretedprotein. May be playing a role in adhesive functions and in cel ...
... Located 8cM telomeric to BCL9; aliases of MUC1 are EMA and CD227. DNA/RNA 3.88 kb, 8 exons, 1721 bp, 2 transcripts. Protein 122.1 kDa (1255 aa) Highly glycosylated protein. The MUC1 protein can be expressed as a transmembrane or secretedprotein. May be playing a role in adhesive functions and in cel ...
Flavin adenine dinucleotide as a chromophore of the Xenopus (6
... the bases to their native forrn (7). In this reaction, the near-UV/blue light photon is used to excite FADI-I- and flavin in the excited state then donates an electron to the CPD and thus FAD is essential for the reaction. The CPD photolyase gene has been isolated from 13 organisms and, on the basis ...
... the bases to their native forrn (7). In this reaction, the near-UV/blue light photon is used to excite FADI-I- and flavin in the excited state then donates an electron to the CPD and thus FAD is essential for the reaction. The CPD photolyase gene has been isolated from 13 organisms and, on the basis ...
Local adaptation to biocontrol agents: A multi-objective data-
... studies by considering diploid inheritance, which is the more realistic case for animals, plants and fungi. ...
... studies by considering diploid inheritance, which is the more realistic case for animals, plants and fungi. ...
Mutator Transposon in Maize and MULEs in the Plant Genome
... transposase, which was used as evidence for its very early origin [13]. The mudrB major transcript encodes a 23 kDa protein (MURB) that is not similar to any sequences in public database outside maize and its close relatives. Although the precise function of MURB remains enigmatic, both deletion der ...
... transposase, which was used as evidence for its very early origin [13]. The mudrB major transcript encodes a 23 kDa protein (MURB) that is not similar to any sequences in public database outside maize and its close relatives. Although the precise function of MURB remains enigmatic, both deletion der ...
Origin of the eukaryotic cell
... the origin of eukaryotic cell (Albani et al. 2010). The relationship among three domains, Eukaryotes, Bacteria and Archaea, in the tree of life was investigated in this project through phylogenies constructed from two mitochondrial transmembrane proteins HSP70 and HSP60. The trees were rooted with a ...
... the origin of eukaryotic cell (Albani et al. 2010). The relationship among three domains, Eukaryotes, Bacteria and Archaea, in the tree of life was investigated in this project through phylogenies constructed from two mitochondrial transmembrane proteins HSP70 and HSP60. The trees were rooted with a ...
Do You Know… Genetics
... A young priest from central Europe named Gregor Mendel began a study of pea plants while tending a monastery garden that led him to an understanding of how traits are passed from parents to offspring. Mendel was the first scientist to recognize that the principles of probability can be used to predi ...
... A young priest from central Europe named Gregor Mendel began a study of pea plants while tending a monastery garden that led him to an understanding of how traits are passed from parents to offspring. Mendel was the first scientist to recognize that the principles of probability can be used to predi ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.