![Gene Section PSF (PTB-associated splicing factor) Atlas of Genetics and Cytogenetics](http://s1.studyres.com/store/data/008922043_1-9ebd754833491b67738d3713f0f1fa78-300x300.png)
Gene Section PSF (PTB-associated splicing factor) Atlas of Genetics and Cytogenetics
... proline/glutamine rich domain, a prolin rich region, 2 tandem RNA binding domains, and C-term. ...
... proline/glutamine rich domain, a prolin rich region, 2 tandem RNA binding domains, and C-term. ...
GREEN FLUORESCENT PROTEIN (GFP) GFP is produced by the
... occasionally the proton does not return to the chromophore, so the neutral chromophore is photoisomerized to the anionic form. Wild-type GFP folds fairly efficiently when expressed at or below room temperature, but its folding efficiency declines steeply at higher temperatures. Presumably this natur ...
... occasionally the proton does not return to the chromophore, so the neutral chromophore is photoisomerized to the anionic form. Wild-type GFP folds fairly efficiently when expressed at or below room temperature, but its folding efficiency declines steeply at higher temperatures. Presumably this natur ...
The Epigenetic Memory Different timing of bud burst between epitypes
... PPR and TPR repeat, Clathrin heavy chains/VPS proteins, etc. , including also genes involved in epigenetic regulation ...
... PPR and TPR repeat, Clathrin heavy chains/VPS proteins, etc. , including also genes involved in epigenetic regulation ...
Cancer Prone Disease Section Chediak-Higashi Syndrome Atlas of Genetics and Cytogenetics
... Figure 1. The structure and mutations of the human LYST gene. Filled box indicate coding sequences. Hatched box indicate 5' and 3' untranslated sequences. Left-hatched indicates 5' untranslated sequences in mRNA containing exons 1 and 3, right-hatched indicates 5' untranslated sequences in mRNAs con ...
... Figure 1. The structure and mutations of the human LYST gene. Filled box indicate coding sequences. Hatched box indicate 5' and 3' untranslated sequences. Left-hatched indicates 5' untranslated sequences in mRNA containing exons 1 and 3, right-hatched indicates 5' untranslated sequences in mRNAs con ...
HMG B domain
... Alternatively splicing gives rise to two isoform proteins, HMGA1a (HMGI) and HMGA1b (HMGY). These two are identical in sequence except for a deletion of 11 residues between the the first and second AT hook in the latter. Alternative splicing also produces HMGA1c. The related HMGA2 (HMGI-C) protein i ...
... Alternatively splicing gives rise to two isoform proteins, HMGA1a (HMGI) and HMGA1b (HMGY). These two are identical in sequence except for a deletion of 11 residues between the the first and second AT hook in the latter. Alternative splicing also produces HMGA1c. The related HMGA2 (HMGI-C) protein i ...
Expediting Purification of Cellular Proteins
... from focusing on small numbers of molecules or cellular events to global functional analysis, feeding these results into new approaches for the prevention, diagnosis, and treatment of cancer. Methods that allow researchers to look across a broader angle at cellular processes such as mRNA expression ...
... from focusing on small numbers of molecules or cellular events to global functional analysis, feeding these results into new approaches for the prevention, diagnosis, and treatment of cancer. Methods that allow researchers to look across a broader angle at cellular processes such as mRNA expression ...
Evaluation of Genotypic variation using SDS-PAGE
... seed storage proteins with a number of stable bands in the gel (Fig.1). Considerable variation was observed with low (1.8±0.02 mg/gm) and high (3.18±0.03 mg/gm) levels in the protein content which was though not reflected in the protein banding patterns. No additional bands were observed in the prot ...
... seed storage proteins with a number of stable bands in the gel (Fig.1). Considerable variation was observed with low (1.8±0.02 mg/gm) and high (3.18±0.03 mg/gm) levels in the protein content which was though not reflected in the protein banding patterns. No additional bands were observed in the prot ...
Interactions of bacterial and viral proteins with mitochondria
... The virulence of pathogenic bacteria and viruses depends on proteins that mediate adhesion to target cells, toxicity or defence against the immune system. An increasing number of these proteins is known to target mitochondria in the cells of infected tissues. It is the aim of the practical course to ...
... The virulence of pathogenic bacteria and viruses depends on proteins that mediate adhesion to target cells, toxicity or defence against the immune system. An increasing number of these proteins is known to target mitochondria in the cells of infected tissues. It is the aim of the practical course to ...
Protein Expression and Purification
... Before you start….. • Construct design – Which cloning protocols? • Identify domains, select domains for expression • e.g. kinase domain from RTKs for assays and structure based drug discovery • Fusion tags ? – Which host cell system? – Which expression vector? ...
... Before you start….. • Construct design – Which cloning protocols? • Identify domains, select domains for expression • e.g. kinase domain from RTKs for assays and structure based drug discovery • Fusion tags ? – Which host cell system? – Which expression vector? ...
UCLA Bioinformatics - Cal State LA
... Why glutaredoxin-like protein? • Only present among hyperthermophiles. • Operates in thiol-disulfide reaction via CXXC motif which either form a disulfide (oxidized form) or a dithiol (reduced form). • Requires for many functions including electron and proton transport to essential enzymes like rib ...
... Why glutaredoxin-like protein? • Only present among hyperthermophiles. • Operates in thiol-disulfide reaction via CXXC motif which either form a disulfide (oxidized form) or a dithiol (reduced form). • Requires for many functions including electron and proton transport to essential enzymes like rib ...
Publication JournalArticle (Originalarbeit in einer wissenschaftlichen
... resolution crystal structure of the atypical methanogenic Methanosarcina barkeri SerRS and its complexes with ATP, serine and the non-hydrolysable seryl-adenylate analogue 5`-O-(N-serylsulfamoyl) adenosine. The structures reveal two idiosyncratic features of methanogenic SerRSs: a novel N-terminal t ...
... resolution crystal structure of the atypical methanogenic Methanosarcina barkeri SerRS and its complexes with ATP, serine and the non-hydrolysable seryl-adenylate analogue 5`-O-(N-serylsulfamoyl) adenosine. The structures reveal two idiosyncratic features of methanogenic SerRSs: a novel N-terminal t ...
Poster - Protein Information Resource
... Correct protein annotation relies on both global (whole protein) and local (domain and motif) sequence similarities. We have developed a method by which annotation of site-specific features can be confidently propagated from experimentallycharacterized proteins to uncharacterized proteins. The metho ...
... Correct protein annotation relies on both global (whole protein) and local (domain and motif) sequence similarities. We have developed a method by which annotation of site-specific features can be confidently propagated from experimentallycharacterized proteins to uncharacterized proteins. The metho ...
Introduction
... Turnover of cellular proteins was discovered in the 1930s in studies of Rudolf Schoenheimer, but it was in the 1960s that is became apparent that this was not just turnover, but a highly selective process. By the end of the 1970s two independent groups were working on two different topics: in the la ...
... Turnover of cellular proteins was discovered in the 1930s in studies of Rudolf Schoenheimer, but it was in the 1960s that is became apparent that this was not just turnover, but a highly selective process. By the end of the 1970s two independent groups were working on two different topics: in the la ...
Supplementary Table S2 (doc 37K)
... N188 belongs to a loop connecting strand 3 to H3, keeping it folded by forming hydrogen bonds with the neighbouring loop 240-255 positioned close to the active site cleft. The replacement with a hydrophobic isoleucine (N188I) is likely to impact upon the correct substrate positioning. In addition th ...
... N188 belongs to a loop connecting strand 3 to H3, keeping it folded by forming hydrogen bonds with the neighbouring loop 240-255 positioned close to the active site cleft. The replacement with a hydrophobic isoleucine (N188I) is likely to impact upon the correct substrate positioning. In addition th ...
Protein C-mannosylation: Facts and questions.
... occurring in ER. Based on this, the hypothesis was ventured that the precursor in the biosynthesis of (C2-Man)-Trp is dolichylphosphate mannose (Dol-P-Man). This was verified by expression of RNase 2.4 in CHO Lec15 cells, in which the Dol-P-Man synthase activity is very low and which contain strongl ...
... occurring in ER. Based on this, the hypothesis was ventured that the precursor in the biosynthesis of (C2-Man)-Trp is dolichylphosphate mannose (Dol-P-Man). This was verified by expression of RNase 2.4 in CHO Lec15 cells, in which the Dol-P-Man synthase activity is very low and which contain strongl ...
The presentation part II
... • Definition: A given codon is used more (less) often to code for an amino acid over different other codons fot the same a.a. • Highly biased mRNAs may use only 25 of the 61 codons. • Different ways to measure C.B exist. • The larger the codon bias value, the smaller the number of codons that are us ...
... • Definition: A given codon is used more (less) often to code for an amino acid over different other codons fot the same a.a. • Highly biased mRNAs may use only 25 of the 61 codons. • Different ways to measure C.B exist. • The larger the codon bias value, the smaller the number of codons that are us ...
Chapter 19. “Completing the knot” Stress on enzyme
... coordinates and on analysis of structure in terms of secondary structures has been so unprofitable. On the positive side the small conformational changes in coordinates in function are probably not much different in dissolved states as in crystals so long as protein activity coefficients are not muc ...
... coordinates and on analysis of structure in terms of secondary structures has been so unprofitable. On the positive side the small conformational changes in coordinates in function are probably not much different in dissolved states as in crystals so long as protein activity coefficients are not muc ...
The samples were dissolved in 25 µL of 100 mM ammonium
... terminal peptides of the smallest protein. When truncating the sequence to GSHM-(23132) within the Sequence Editor Matcher, the calculated intact protein average mass of 12524.50 was 2 Da larger than the measured mass of 12522.69. The addition of a disulfide would reduce the mass to 12522.49, which ...
... terminal peptides of the smallest protein. When truncating the sequence to GSHM-(23132) within the Sequence Editor Matcher, the calculated intact protein average mass of 12524.50 was 2 Da larger than the measured mass of 12522.69. The addition of a disulfide would reduce the mass to 12522.49, which ...
Name: Date
... acids) needed to make the secret weapon (polypeptide; protein). They bring the parts to the door of the factory (ribosome; rRNA). The master plans (DNA) are encoded (transcribed) and given to the messenger (mRNA) to deliver and oversee the production (translation) of the secret weapon (polypeptide, ...
... acids) needed to make the secret weapon (polypeptide; protein). They bring the parts to the door of the factory (ribosome; rRNA). The master plans (DNA) are encoded (transcribed) and given to the messenger (mRNA) to deliver and oversee the production (translation) of the secret weapon (polypeptide, ...
Protein domain
![](https://commons.wikimedia.org/wiki/Special:FilePath/Pyruvate_kinase_protein_domains.png?width=300)
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins. Molecular evolution uses domains as building blocks and these may be recombined in different arrangements to create proteins with different functions. Domains vary in length from between about 25 amino acids up to 500 amino acids in length. The shortest domains such as zinc fingers are stabilized by metal ions or disulfide bridges. Domains often form functional units, such as the calcium-binding EF hand domain of calmodulin. Because they are independently stable, domains can be ""swapped"" by genetic engineering between one protein and another to make chimeric proteins.