Properties of spontaneous mutations affecting quantitative traits
... the expression of fitness components of Daphnia, which is known to be a very sensitive organism, and could have reduced the final performance of the disregarded control. Therefore, these data should be accepted with caution. Putting together results from such diverse species is speculative, involvin ...
... the expression of fitness components of Daphnia, which is known to be a very sensitive organism, and could have reduced the final performance of the disregarded control. Therefore, these data should be accepted with caution. Putting together results from such diverse species is speculative, involvin ...
Natural variation in monoterpene synthesis in kiwifruit
... signaling (Kou et al., 2012). Studies in banana have shown that expression levels of several ...
... signaling (Kou et al., 2012). Studies in banana have shown that expression levels of several ...
PCDH19-related Infantile Epileptic Encephalopathy - HAL
... In contrast, females with heterozygous PCDH19 mutations present with early intractable seizures and a variable degree of mental retardation. PCDH19 is located in a region submitted to Xinactivation in females [Dibbens et al., 2008]. Random X-inactivation in mutated females is expected to lead to tis ...
... In contrast, females with heterozygous PCDH19 mutations present with early intractable seizures and a variable degree of mental retardation. PCDH19 is located in a region submitted to Xinactivation in females [Dibbens et al., 2008]. Random X-inactivation in mutated females is expected to lead to tis ...
Linkage and Linkage Disequilibrium
... rapidly from a small group of ancestors. For example, the 5,000,000 Finns mostly descended from about 1000 people who lived about 2000 years ago. Such a population is prone to allelic disequilibrium. •Selection: When an individual’s genotype influences his/her reproductive fitness. For example, if t ...
... rapidly from a small group of ancestors. For example, the 5,000,000 Finns mostly descended from about 1000 people who lived about 2000 years ago. Such a population is prone to allelic disequilibrium. •Selection: When an individual’s genotype influences his/her reproductive fitness. For example, if t ...
AnsteadSeniorHonorsThesis
... of Mcm10 in cancer is not yet fully known. One way to study a gene is to see the effects when it is no longer functioning. When eukaryotic organisms are homozygous deficient for Mcm10 they are still able to function despite the complete loss of the Mcm10 protein (Christensen, T. 2003). This suggests ...
... of Mcm10 in cancer is not yet fully known. One way to study a gene is to see the effects when it is no longer functioning. When eukaryotic organisms are homozygous deficient for Mcm10 they are still able to function despite the complete loss of the Mcm10 protein (Christensen, T. 2003). This suggests ...
Single-stranded heteroduplex intermediates in l Red homologous
... recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermediates to establish single stranded heteroduplexes at the replication fork. We created asymmetrically dige ...
... recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermediates to establish single stranded heteroduplexes at the replication fork. We created asymmetrically dige ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... The Progins Progesterone Receptor Gene Polymorphism and Polymorphism of the Estrogen … variants may influence cell proliferation, viability, and apoptosis in endometrial cell metabolism. Wieser et al., [14] Lattuada et al., [17] and Carvalho et al.[18] demonstrated a significant correlation between ...
... The Progins Progesterone Receptor Gene Polymorphism and Polymorphism of the Estrogen … variants may influence cell proliferation, viability, and apoptosis in endometrial cell metabolism. Wieser et al., [14] Lattuada et al., [17] and Carvalho et al.[18] demonstrated a significant correlation between ...
Interaction of nonsense suppressor tRNAs and codon nonsense
... are stimulated in their reading of both UAG/A with preference for UAG [14]. Of all the E. coli tRNA genes that can give rise to an amber or an ochre suppressor by a singlenucleotide mutation except for the tRNAGlu genes. A sitespecific mutagenesis is used to create the gene for such a tRNA in order ...
... are stimulated in their reading of both UAG/A with preference for UAG [14]. Of all the E. coli tRNA genes that can give rise to an amber or an ochre suppressor by a singlenucleotide mutation except for the tRNAGlu genes. A sitespecific mutagenesis is used to create the gene for such a tRNA in order ...
Heliconius wing patterns: an evo-devo model for understanding
... McMillan, 1997; Gilbert, 2003; Naisbit et al, 2003). These studies demonstrate that colour-pattern differences between closely related species appear to be caused by allelic differences at same loci that are responsible for phenotypic differences within a species (Table 1). This is true even when sp ...
... McMillan, 1997; Gilbert, 2003; Naisbit et al, 2003). These studies demonstrate that colour-pattern differences between closely related species appear to be caused by allelic differences at same loci that are responsible for phenotypic differences within a species (Table 1). This is true even when sp ...
DnaJ-related protein essential for placentation - Development
... showed no abnormal phenotypes in other trophoblast cell types or in the embryo proper. This study indicates a previously unsuspected role for chaperone proteins in placental development and represents the first genetic analysis of DnaJ-related protein function in higher eukaryotes. Based on a survey ...
... showed no abnormal phenotypes in other trophoblast cell types or in the embryo proper. This study indicates a previously unsuspected role for chaperone proteins in placental development and represents the first genetic analysis of DnaJ-related protein function in higher eukaryotes. Based on a survey ...
MEF2 activity during embryogenesis - Development
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
View as PDF
... termini of histones H3 and H4 (15). Combined immunofluorescence and in situ-hybridization experiments have shown that telomeres are clustered and that Rap1p, Sir3p, and Sir4p colocalize with telomeric foci in wild-type cells (9). Immunoprecipitation and cross-linking data confirm that Sir3p, Sir4p, ...
... termini of histones H3 and H4 (15). Combined immunofluorescence and in situ-hybridization experiments have shown that telomeres are clustered and that Rap1p, Sir3p, and Sir4p colocalize with telomeric foci in wild-type cells (9). Immunoprecipitation and cross-linking data confirm that Sir3p, Sir4p, ...
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)
... Korenberg et al., 1996; Robinson et al., 1996). However, the number of expressed genes in these duplicated regions and their contribution to the WMS phenotype is unknown. The current report will illustrate the structure of the flanking duplications and suggest a possible relationship to the WMS brea ...
... Korenberg et al., 1996; Robinson et al., 1996). However, the number of expressed genes in these duplicated regions and their contribution to the WMS phenotype is unknown. The current report will illustrate the structure of the flanking duplications and suggest a possible relationship to the WMS brea ...
a genetic algorithm for the automatic generation of
... A Genetic Algorithm (GA)[7][8] is a stochastic search algorithm that aims to find good solutions to difficult problems by applying the principles of evolutionary biology. Evolutionary concepts such as natural selection, mutation and crossover are applied to a “population” of solutions in order to ev ...
... A Genetic Algorithm (GA)[7][8] is a stochastic search algorithm that aims to find good solutions to difficult problems by applying the principles of evolutionary biology. Evolutionary concepts such as natural selection, mutation and crossover are applied to a “population” of solutions in order to ev ...
Linköping University Post Print Segment-specific generation of Drosophila
... defective (hid), and grim, that each contain a conserved NH2-terminal Rpr, Hid, Grim (RHG) motif (Bergmann et al., 2003). The deficiency Df(3L)H99 (H99) removes these genes (Fig. 2G), and embryos homozygous for H99 displays complete absence of PCD (White et al., 1994). Late H99 embryos (18hAEL) inde ...
... defective (hid), and grim, that each contain a conserved NH2-terminal Rpr, Hid, Grim (RHG) motif (Bergmann et al., 2003). The deficiency Df(3L)H99 (H99) removes these genes (Fig. 2G), and embryos homozygous for H99 displays complete absence of PCD (White et al., 1994). Late H99 embryos (18hAEL) inde ...
Engineering of steroid biotransformation in rhodococcus van
... deduced amino acid sequences of kshA and kshB showed that KshA and KshB both are [2Fe-2S] containing enzymes, harboring highly conserved domains typically found in class IA terminal oxygenases and class IA oxygenase-reductases. Class IA oxygenases by definition are twocomponent oxygenases, classifiy ...
... deduced amino acid sequences of kshA and kshB showed that KshA and KshB both are [2Fe-2S] containing enzymes, harboring highly conserved domains typically found in class IA terminal oxygenases and class IA oxygenase-reductases. Class IA oxygenases by definition are twocomponent oxygenases, classifiy ...
Topology optimization of planar Integrated Lichtwave circuits.
... creating a physical prototype, to assess design risks, and to assist in the discovery of new products by creating the question “what if” product scenarios. But a real dedicated optimization system is not yet been establish. The optimizer part is based on an evolutionary approach. The particularly co ...
... creating a physical prototype, to assess design risks, and to assist in the discovery of new products by creating the question “what if” product scenarios. But a real dedicated optimization system is not yet been establish. The optimizer part is based on an evolutionary approach. The particularly co ...
Cytoplasmic male sterility
... not set any seed under bags. However, female fertility is evidently complete, since routine hand-pollinations with cv. Adorra for backcrosses resulted in a 95.9% seed set in 1078 florets of 50 spikes. In spikes under bags, partial fertility in the F1 hybrid 79BS14-3/Adorra was also found in the 1981 ...
... not set any seed under bags. However, female fertility is evidently complete, since routine hand-pollinations with cv. Adorra for backcrosses resulted in a 95.9% seed set in 1078 florets of 50 spikes. In spikes under bags, partial fertility in the F1 hybrid 79BS14-3/Adorra was also found in the 1981 ...
Gene quantification using real-time quantitative PCR
... DNA copy number measurements are important in determining the extent of genomic imbalance that underlies most malignancies. There are numerous techniques available for measuring DNA copy number in tumors; each method has specific advantages and disadvantages. Chromosomal CGH can detect imbalances ac ...
... DNA copy number measurements are important in determining the extent of genomic imbalance that underlies most malignancies. There are numerous techniques available for measuring DNA copy number in tumors; each method has specific advantages and disadvantages. Chromosomal CGH can detect imbalances ac ...
The relationship between higher‑order chromatin structure and
... transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly than bulk chromatin or a non‑expressed gene, whereas it sediments with bulk chromatin in non‑expressing cells [8,9,11]. Ho ...
... transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly than bulk chromatin or a non‑expressed gene, whereas it sediments with bulk chromatin in non‑expressing cells [8,9,11]. Ho ...
Slide 1
... Genetic Markers and NCE • Genetic Markers have the potential to improve the effectiveness of NCE • However, for most traits, genetic markers will not account for enough of the genetic variation to allow them to be used as the only selection criterion • Instead, methods must be developed to combine ...
... Genetic Markers and NCE • Genetic Markers have the potential to improve the effectiveness of NCE • However, for most traits, genetic markers will not account for enough of the genetic variation to allow them to be used as the only selection criterion • Instead, methods must be developed to combine ...
The somatic-visceral subdivision of the embryonic mesoderm is
... number of invaginating cells Previous studies suggest a correlation between the limits of the sna expression pattern and the extent of the ventral furrow (Ip et al., 1994). To obtain more rigorous evidence that the narrowed sna pattern results in a reduction in mesoderm invagination, embryos were do ...
... number of invaginating cells Previous studies suggest a correlation between the limits of the sna expression pattern and the extent of the ventral furrow (Ip et al., 1994). To obtain more rigorous evidence that the narrowed sna pattern results in a reduction in mesoderm invagination, embryos were do ...