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Characterisation of the katA gene encoding a catalase and evidence
Characterisation of the katA gene encoding a catalase and evidence

... 20-kb EcoRI fragment is detected in the wild-type, which is substantially shortened in the TX350 DNA due to the introduction of an EcoRI restriction site within the ermB cassette (data not shown). In addition to the katA-containing band, a second weaker hybridisation signal of about 4.5 kb was detec ...
Silent polymorphisms in the RYR1 gene do not modify the
Silent polymorphisms in the RYR1 gene do not modify the

... particular attention to the C-terminal region. Recent next- generation sequencing methods are now identifying multiple numbers of variants in patients, in which interpretation and phenotype prevision is difficult. Case presentation: In a Brazilian Caucasian family, clinical, histopathological and mo ...
The Evolutionary Biology of Decision Making
The Evolutionary Biology of Decision Making

... into the decision process. The decision process then generates a decision, which possibly leads to an action and outcome. Selection pressures such as natural selection, reinforcement learning, and functional evaluation can alter the decision mechanism by providing feedback about the realized or poss ...
X-linked
X-linked

... development, and the ability to have children (fertility). The signs and symptoms of these conditions vary widely and range from mild to severe. They can be caused by missing or extra copies of the sex chromosomes or by structural changes in these chromosomes. AP Biology ...
Characterization of the Arabidopsis thaliana Mutant pcb2 which
Characterization of the Arabidopsis thaliana Mutant pcb2 which

... The pcb2-related genes are found in higher plants, Chlorobium tepidum TLS and Synechococcus sp. WH8102, but not in other sequenced genomes of photosynthetic prokaryotes. In Rhodobacter capsulate and C. tepidum TLS, bchJ was identified as divinyl protochlorophyllide 8-vinyl reductase by genetic metho ...
quantitative genetics - E-Learning/An
quantitative genetics - E-Learning/An

... interest varies in a symmetrical way around an average value. The distribution of measurements of many biological characteristics is approximated by a symmetrical bell curve like that in Figure 25.1b. Normal distributions are common when the phenotype is determined by the cumulative effect of many s ...
The DUET gene is necessary for chromosome
The DUET gene is necessary for chromosome

... et al., 2001) and several genes have also been characterized at the molecular level. The ASK1 gene is required for homologue separation during male meiosis (Yang et al., 1999a). The DYAD/SWI1 gene is required for meiotic chromosome organization and meiotic progression (Mercier et al., 2001; Agashe e ...
Pathway Analysis using Partek Genomics Suite® 6.6 and Partek
Pathway Analysis using Partek Genomics Suite® 6.6 and Partek

... When assessing the results both the Enrichment Score and the “Factor” Score should be used. While you will intuitively want to sort by the Enrichment Score (indeed Pathway sorts by this column as the default option) this can sometimes be misleading. For example, if the number of genes in the entire ...
PCR-based Markers and Cut Flower Longevity in Carnation
PCR-based Markers and Cut Flower Longevity in Carnation

... The amplification patterns of the commercial varieties were compared to Roland and Milady fragments (Table 1). A score was calculated based on the similarity of each of 23 bands analyzed with ‘Roland’ (1) or ‘Milady’ (0). The individuals with longer vase life did not show higher scores compared to t ...
Neural Network Structures
Neural Network Structures

... from original device physics simulators or from device measurements. Training is done to determine neural network internal weights w such that the neural model output best matches the training data. A trained neural network model can then be used during microwave design providing answers to the task ...
A program for annotating and predicting the effects of single
A program for annotating and predicting the effects of single

... estimated. One might thing that if a large fraction of the identified SNPs had the predicted “effects”, the organism would not be viable. However, since short-read next-generation sequencing has a high error rate, such as the short-read sequences we obtained with the Illumina platform, further valid ...
Experimental studies of deleterious mutation in Saccharomyces
Experimental studies of deleterious mutation in Saccharomyces

... genetics is less well known. Among its advantages is the ease of screening for mutants. The present paper reviews experiments aimed at estimating the parameters of spontaneous mutations deleterious to fitness. The rate of deleterious mutation was found to be moderately high. A large fraction of dete ...
Direct fitness or inclusive fitness: How shall we model kin selection?
Direct fitness or inclusive fitness: How shall we model kin selection?

... Phenotypic value of the kth actor belonging to the social group of the focal individual Normal phenotypic value cov(G,Pk)/cov(G,P), the relatedness of the kth actor to the focal recipient in his social group (direct fitness arguments), or cov(Gk,P)/cov(G,P), the relatedness of the focal actor to the ...
Automata-based adaptive behavior for economic modeling using
Automata-based adaptive behavior for economic modeling using

... allowing to recognize languages, another approach consists in associating to the automata a functional goal. In addition of accepted letter from an alphabet as the condition of a transition, we add for each transition an information which can be considered as an output data of the transition, the re ...
A Survey of Diversity-Oriented Optimization 1 Introduction - IC
A Survey of Diversity-Oriented Optimization 1 Introduction - IC

... algorithm that searches for several good (not necessarily optimal) but maximally different solutions. In complex problem fields and search spaces, such as drug discovery, only by looking at a solution it can be judged by a domain expert, whether or not that solution is really suitable. The famous ch ...
Efficient gene transduction of neurons by lentivirus with
Efficient gene transduction of neurons by lentivirus with

... GFP expression by neuron-specific and enhanced neuron-specific promoters in the rat neostriatum, thalamus and neocortex We generated 11 kinds of VSV-G-pseudotyped lentiviral vectors, which express GFP under CMV, neuron-specific and enhanced neuron-specific promoters (Figure 1, Table 1). At 1 week af ...
Imprinting in the endosperm: a possible role in preventing wide
Imprinting in the endosperm: a possible role in preventing wide

... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
Heavy Chain Diversity Region Segments of the Channel Catfish
Heavy Chain Diversity Region Segments of the Channel Catfish

... flanking region of the respective JH segment continued further upstream (data not shown), and in each clone, the JH coding and 3⬘-flanking regions were absent. This indicated that each clone represents an extrachromosomal product of a recombination event between a germline JH gene segment and a puta ...
Functional Genomics
Functional Genomics

... Several of the articles in this Insight discuss new technologies that are being developed to understand function on a genome-wide scale. Are these approaches conceptually different from what biologists have been doing for many years, or is it just the scale on which experiments can be done that is d ...
Preview Sample 2
Preview Sample 2

... (1) Peas have a fairly rapid generation time (at least two generations per year if grown in the field, three or four generations per year if grown in greenhouses. (2) Peas can either self-fertilize or be artificially crossed by an experimenter. (3) Peas produce large numbers of offspring (hundreds p ...
Cot-1 banding of human chromosomes using fluorescence
Cot-1 banding of human chromosomes using fluorescence

... banding pattern and the resolution is sufficient for locating a hybridization signal on banded chromosomes. This could be useful for more precise analysis of chromosome aberrations and gene localization. The scanning analysis revealed that some Cot-1 bands and Q-bands are overlapped as seen for the ...
PDF - Journal of Genomics
PDF - Journal of Genomics

... biotypes of the soybean aphid have been identified in Midwest growing regions; biotypes are based on the ability to overcome host-plant resistance provided by one or more of these Rag genes. Biotype 2 can override the Rag1 gene (27), while biotype 3 can deride Rag2 resistance (28). Biotype 4 is capa ...
Expression of p53 Target Genes in the Early Phase of Long
Expression of p53 Target Genes in the Early Phase of Long

... synaptic plasticity [12, 13]. Thus, which functional consequences might the brief activation of p53 have? The control of the transcriptional activity of p53 is considered crucial for determining which p53 response is activated [5]. In this paper, we describe the expression of p53-related genes in th ...
Inheritance and the muscular dystrophies
Inheritance and the muscular dystrophies

... The way in which our bodies grow and work is controlled by structures called genes. Genes are parts of chromosomes, which are strands of biochemical material transmitted from every cell to its offspring. We have two genes for every hereditary characteristic and function, one inherited from each pare ...
Perspectives
Perspectives

... power to be “haplo-sufficient” (two copies of an impaired allele neededtoproducemajorphenotypic damage). Going beyond WRIGHT,they claimed that allozymes should therefore have little phenotypic effect, but this does not follow because: Many pathways are not selected to focus control on a few rate-lim ...
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Gene expression programming

In computer programming, gene expression programming (GEP) is an evolutionary algorithm that creates computer programs or models. These computer programs are complex tree structures that learn and adapt by changing their sizes, shapes, and composition, much like a living organism. And like living organisms, the computer programs of GEP are also encoded in simple linear chromosomes of fixed length. Thus, GEP is a genotype-phenotype system, benefiting from a simple genome to keep and transmit the genetic information and a complex phenotype to explore the environment and adapt to it.
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