genetics and the fitness of hybrids
... The preceding quotes illustrate the historically common view of natural hybridization as an evolutionarily unimportant process. This view is largely based on the observation that crosses between divergent lineages often give rise to progeny with decreased levels of viability and/or fertility (e.g., ...
... The preceding quotes illustrate the historically common view of natural hybridization as an evolutionarily unimportant process. This view is largely based on the observation that crosses between divergent lineages often give rise to progeny with decreased levels of viability and/or fertility (e.g., ...
1 Tuning of recombinant protein expression in Escherichia
... several mechanisms. Every stage in the process, from DNA transcription to protein folding dynamics, is tightly regulated to ensure that proteins are produced in required amounts, at the correct times and with minimal waste of energy and resources1. In bacteria, the transcription of DNA to mRNA and t ...
... several mechanisms. Every stage in the process, from DNA transcription to protein folding dynamics, is tightly regulated to ensure that proteins are produced in required amounts, at the correct times and with minimal waste of energy and resources1. In bacteria, the transcription of DNA to mRNA and t ...
Overrepresentation of the COL3A1 AA genotype in Polish skiers with
... ACL-injured group was significantly different than in CON (respectively: AA=10.1 vs 2.2%, AG=22.5 vs 36.1, GG=67.4 vs 61.8%; p=0.0087). The AA vs AG+GG genotype of COL3A1 (odds ratio (OR) = 5.05; 95% confidence interval (CI), 1.62-15.71, p = 0.003) was significantly overrepresented in the ACL-injure ...
... ACL-injured group was significantly different than in CON (respectively: AA=10.1 vs 2.2%, AG=22.5 vs 36.1, GG=67.4 vs 61.8%; p=0.0087). The AA vs AG+GG genotype of COL3A1 (odds ratio (OR) = 5.05; 95% confidence interval (CI), 1.62-15.71, p = 0.003) was significantly overrepresented in the ACL-injure ...
... chicken carcasses in Canada. In a study on cellulitis in chicken carcasses in Iran, Derakhshanfar et al. (2002) isolated Escherichia coli in 91.8% of the carcasses, and reported that E. coli strains were associated or not with Staphylococcus aureus. Actinomyces pyogenes and Staphylococcus aureus wer ...
Activation of the JNK pathway during dorsal closure in Drosophila
... JNKKKs. Many questions remain, such as why are there so many distinct kinase families at this level of the signaling hierarchy? Perhaps each kinase family interprets a distinct upstream signal or participates in unique cellular and developmental processes. Loss-of-function analysis will be a crucial ...
... JNKKKs. Many questions remain, such as why are there so many distinct kinase families at this level of the signaling hierarchy? Perhaps each kinase family interprets a distinct upstream signal or participates in unique cellular and developmental processes. Loss-of-function analysis will be a crucial ...
Rule Insertion and Rule Extraction from Evolving Fuzzy
... from [6, 15, 16] and from other known NN techniques, but here all nodes in an EFuNN are created during (possibly one-pass) learning. The nodes representing MF (fuzzy label neurons) can be modified during learning. As in FuNN, each input variable is represented here by a group of spatially arranged n ...
... from [6, 15, 16] and from other known NN techniques, but here all nodes in an EFuNN are created during (possibly one-pass) learning. The nodes representing MF (fuzzy label neurons) can be modified during learning. As in FuNN, each input variable is represented here by a group of spatially arranged n ...
Note: Alleles are alternative forms of a, gene which occupies a
... (c) What is the genotype of Jane's husband? Jane's husband must be heterozygous (Nn). (1) (d) Explain your reasoning. If he were homozygous (NN) all his children would receive a dominant allele and none could exhibit PKU. (1) (e) What are the chances that Peter is the carrier of the PKU allele that ...
... (c) What is the genotype of Jane's husband? Jane's husband must be heterozygous (Nn). (1) (d) Explain your reasoning. If he were homozygous (NN) all his children would receive a dominant allele and none could exhibit PKU. (1) (e) What are the chances that Peter is the carrier of the PKU allele that ...
Loss-of-function of a Rice Gibberellin Biosynthetic Gene, GA20
... Molecular cloning, mapping and DNA sequencing Degenerate primers were designed from the consensus sequences of the GA20 oxidase gene (GA20ox) (Toyomasu et al. 1997) from rice and Arabidopsis (GA5) (Xu et al. 1995) (sense: 5′YTNCCNTGGAAYGARACNYT3′ and antisense: 5′GTNGGRTCRCARTGNGG3′). The DNA fragme ...
... Molecular cloning, mapping and DNA sequencing Degenerate primers were designed from the consensus sequences of the GA20 oxidase gene (GA20ox) (Toyomasu et al. 1997) from rice and Arabidopsis (GA5) (Xu et al. 1995) (sense: 5′YTNCCNTGGAAYGARACNYT3′ and antisense: 5′GTNGGRTCRCARTGNGG3′). The DNA fragme ...
Molecular Imaging - Engineering Computing Facility
... (technological methods) make their usefulness limited in many circumstances. This is mainly due to the fact that most imaging modalities only provide information at the anatomical level, which is insufficient for diseases at the genetic or molecular level. For instance, in cancer diagnosis and follo ...
... (technological methods) make their usefulness limited in many circumstances. This is mainly due to the fact that most imaging modalities only provide information at the anatomical level, which is insufficient for diseases at the genetic or molecular level. For instance, in cancer diagnosis and follo ...
Abundance and distribution of Macrolide
... Eight detected MLS resistance genes (erm(B), erm(F), erm(T), erm(X), msr(D), mef(A), ere(A), mph(B)), three detected mobile elements (intI1, ISCR1, Tn916/1545), and the 16S rRNA genes were quantified for all samples using SYBR-Green real-time qPCR, with the same primers as conventional PCR. Standard ...
... Eight detected MLS resistance genes (erm(B), erm(F), erm(T), erm(X), msr(D), mef(A), ere(A), mph(B)), three detected mobile elements (intI1, ISCR1, Tn916/1545), and the 16S rRNA genes were quantified for all samples using SYBR-Green real-time qPCR, with the same primers as conventional PCR. Standard ...
WW Genetic Counselor English - Wonderwise
... Meet Cathy Burson, genetic counselor. Cathy works in a hospital clinic, where she sees people of all ages. Adults and kids visit her with different kinds of health problems that might be passed on from one generation to the next. You probably know that we inherit features such as our hair or eye col ...
... Meet Cathy Burson, genetic counselor. Cathy works in a hospital clinic, where she sees people of all ages. Adults and kids visit her with different kinds of health problems that might be passed on from one generation to the next. You probably know that we inherit features such as our hair or eye col ...
Replication of plasmids with the p15A origin in Shewanella
... Shewanella putrefaciens MR-1 (Myers and Nealson 1988a) and Escherichia coli JM109 (Yanisch-Perron et al. 1985) were grown aerobically on LB medium (Sambrook et al. 1989) supplemented, as needed, with antibiotics at the following concentrations : tetracycline (Tc), 8 mg ml−1 and chloramphenicol (Cm), ...
... Shewanella putrefaciens MR-1 (Myers and Nealson 1988a) and Escherichia coli JM109 (Yanisch-Perron et al. 1985) were grown aerobically on LB medium (Sambrook et al. 1989) supplemented, as needed, with antibiotics at the following concentrations : tetracycline (Tc), 8 mg ml−1 and chloramphenicol (Cm), ...
- Journal of Clinical Investigation
... screens are done, will we have learned anything new about the nature of regulation of vertebrate development. The genetic screens The approach of a genome-wide saturation mutagenesis screen is new to vertebrates. Its premise is that mutation of single genes may produce phenotypes which are informati ...
... screens are done, will we have learned anything new about the nature of regulation of vertebrate development. The genetic screens The approach of a genome-wide saturation mutagenesis screen is new to vertebrates. Its premise is that mutation of single genes may produce phenotypes which are informati ...
Microarrays
... provided. Analysis of mock spiked PIF samples revealed sensitivity in the range of 1–10 cfu/25 g sample after biological pre-enrichment. A proof-of-principle study was performed with 21 batches of PIF samples obtained from different sources; two samples were positive for one of the tested pathogens ...
... provided. Analysis of mock spiked PIF samples revealed sensitivity in the range of 1–10 cfu/25 g sample after biological pre-enrichment. A proof-of-principle study was performed with 21 batches of PIF samples obtained from different sources; two samples were positive for one of the tested pathogens ...
Chromosomal breakpoint positions suggest a direct role for radiation
... was not always linear, leading to a model of chromatin arrangement in ¯exible loops of several Mbp arranged along the chromosomal backbone (Yokota et al., 1995). Thus, although two chromosomal loci are located at a considerable linear distance from each other (such as the ELE1 and RET genes), they m ...
... was not always linear, leading to a model of chromatin arrangement in ¯exible loops of several Mbp arranged along the chromosomal backbone (Yokota et al., 1995). Thus, although two chromosomal loci are located at a considerable linear distance from each other (such as the ELE1 and RET genes), they m ...
Concept_Paper
... organism at the forefront of fundamental research. This is particularly the case in areas that are less accessible to in vivo experimental investigation in other model organisms, such as regulated secretion, cell motility, phagocytosis, telomere function, function of post-translational modifications ...
... organism at the forefront of fundamental research. This is particularly the case in areas that are less accessible to in vivo experimental investigation in other model organisms, such as regulated secretion, cell motility, phagocytosis, telomere function, function of post-translational modifications ...
- NRC Research Press
... and shown to form a homoeologous series (Galiba et al. 1995; Snape et al. 1998). Aneuploid analysis has shown that removal of chromosomes 5A, 5B, and 5D delays flowering under unvernalized conditions (Flood and Halloran 1986). Thus, any deletion lines lacking the vernalization response genes would b ...
... and shown to form a homoeologous series (Galiba et al. 1995; Snape et al. 1998). Aneuploid analysis has shown that removal of chromosomes 5A, 5B, and 5D delays flowering under unvernalized conditions (Flood and Halloran 1986). Thus, any deletion lines lacking the vernalization response genes would b ...
Large-scale attribute selection using wrappers
... when coupled with other attributes. Also, k may not be large enough to comprise all relevant attributes. However, the experimental results in Section V-A show that the performance of this method is competitive to a full forward selection on the datasets we tested. Note that the overall number of eva ...
... when coupled with other attributes. Also, k may not be large enough to comprise all relevant attributes. However, the experimental results in Section V-A show that the performance of this method is competitive to a full forward selection on the datasets we tested. Note that the overall number of eva ...
Large-scale attribute selection using wrappers
... when coupled with other attributes. Also, k may not be large enough to comprise all relevant attributes. However, the experimental results in Section V-A show that the performance of this method is competitive to a full forward selection on the datasets we tested. Note that the overall number of eva ...
... when coupled with other attributes. Also, k may not be large enough to comprise all relevant attributes. However, the experimental results in Section V-A show that the performance of this method is competitive to a full forward selection on the datasets we tested. Note that the overall number of eva ...
Journal of Autoimmunity - The Lu
... patterns of V gene expression were detected in both the left and right capsules from individuals independent of their clinical status (i.e., symptomatic and asymptomatic patients). A representative TCR BV CDR3 spectratype analysis of RNA from PBL, left capsule, and right capsule from patient #1 is i ...
... patterns of V gene expression were detected in both the left and right capsules from individuals independent of their clinical status (i.e., symptomatic and asymptomatic patients). A representative TCR BV CDR3 spectratype analysis of RNA from PBL, left capsule, and right capsule from patient #1 is i ...
Increased sex chromosome expression and epigenetic
... 2006). However, the X and Y chromosomes are continually remodelled during the transition between meiosis and spermiogenesis, and histone modifications associated with transcriptionally active chromatin [e.g. histone acetylation and histone H3 dimethylated on lysine 4 (H3K4me2)] are also enriched on ...
... 2006). However, the X and Y chromosomes are continually remodelled during the transition between meiosis and spermiogenesis, and histone modifications associated with transcriptionally active chromatin [e.g. histone acetylation and histone H3 dimethylated on lysine 4 (H3K4me2)] are also enriched on ...
ppt
... VI. Levels of Selection Selection can occur wherever there is differential reproduction among variable entities. ...
... VI. Levels of Selection Selection can occur wherever there is differential reproduction among variable entities. ...
Kinds of gene rearrangement
... facts), while unsuccessful hypotheses are often marked by containing one or more jictae causae (imagined statements). The first hypothesis as to crossing over seems to have been that of JANSSENS (1909), who predicted exchange of parts of homologous chromosomes, from his observations of chiasmas. I n ...
... facts), while unsuccessful hypotheses are often marked by containing one or more jictae causae (imagined statements). The first hypothesis as to crossing over seems to have been that of JANSSENS (1909), who predicted exchange of parts of homologous chromosomes, from his observations of chiasmas. I n ...
The hidden complexity of Mendelian traits across yeast
... monogenic traits can be influenced by multiple genes in specific genetic backgrounds5-9. In fact, it is increasingly evident that monogenic mutations do not always strictly adhere to Mendelian inheritance6-8. For example, many human monogenic disorders, including sickle cell anemia and cystic fibros ...
... monogenic traits can be influenced by multiple genes in specific genetic backgrounds5-9. In fact, it is increasingly evident that monogenic mutations do not always strictly adhere to Mendelian inheritance6-8. For example, many human monogenic disorders, including sickle cell anemia and cystic fibros ...
Parents AUTOSOMAL RECESSIVE: one parent affected
... Brother with deafness Parents with normal hearing ...
... Brother with deafness Parents with normal hearing ...