illuminaHumanv3.db October 28, 2014
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
Transgenic Mice for Intersectional Targeting of Neural Sensors and
... presumably with multiple copies at the insertion site. Although powerful in driving tool gene expression, this approach also has drawbacks. Expression of transgenes driven by the Thy1.2 promoter is strongly position dependent, necessitating a screen of multiple founder lines to find potentially usef ...
... presumably with multiple copies at the insertion site. Although powerful in driving tool gene expression, this approach also has drawbacks. Expression of transgenes driven by the Thy1.2 promoter is strongly position dependent, necessitating a screen of multiple founder lines to find potentially usef ...
Title An Evolutionary Approach to Automatic Kernel Construction
... space, where φ(x) represents the mapping to this feature space. The SVM finds the maximum margin separating hyperplane in the feature space defined by this kernel, thus yielding a non-linear decision boundary in the original input space. With the use of kernel functions, it is possible to compute th ...
... space, where φ(x) represents the mapping to this feature space. The SVM finds the maximum margin separating hyperplane in the feature space defined by this kernel, thus yielding a non-linear decision boundary in the original input space. With the use of kernel functions, it is possible to compute th ...
"Nitrogen Fixation: 1888-2001"
... Nitrogen fixation genes have been identified in a number of cyanobacteria but have been characterised in most detail in Anabaena PCC7120, Anabaena variabilis ATCC 29413 and Synechococcus strain RF-1. Nitrogen-fixing cyanobacteria can be divided into those species in which nitrogen fixation occurs in ...
... Nitrogen fixation genes have been identified in a number of cyanobacteria but have been characterised in most detail in Anabaena PCC7120, Anabaena variabilis ATCC 29413 and Synechococcus strain RF-1. Nitrogen-fixing cyanobacteria can be divided into those species in which nitrogen fixation occurs in ...
Boundary elements and nuclear organization
... recruitment of specific activities to a limited locus, or targeting to a subnuclear compartment associated with either silencing or activation. All of these mechanisms may involve the action of specialized regulatory elements, which phenotypically would behave as chromatin domain boundaries. Such el ...
... recruitment of specific activities to a limited locus, or targeting to a subnuclear compartment associated with either silencing or activation. All of these mechanisms may involve the action of specialized regulatory elements, which phenotypically would behave as chromatin domain boundaries. Such el ...
RNA Interference and Small Interfering RNAs
... responsible for the systemic spreading of RNAi in the worm. It is interesting to note that the heritable agent is still maintained and most likely replicated in rde-1 mutant worms (see Section 3.3) that can no longer initiate RNAi by injection of long dsRNAs.[53] This could suggest that dsRNA proces ...
... responsible for the systemic spreading of RNAi in the worm. It is interesting to note that the heritable agent is still maintained and most likely replicated in rde-1 mutant worms (see Section 3.3) that can no longer initiate RNAi by injection of long dsRNAs.[53] This could suggest that dsRNA proces ...
BRAIN Clinical and genetic diversity of SMN1-negative proximal spinal muscular atrophies
... Landoure et al., 2010). These different phenotypes may even occur within the same family (Auer-Grumbach et al., 2010) and might have an incomplete penetrance (Berciano et al., 2011). In addition, heterozygous TRPV4 mutations are responsible for various skeletal dysplasias (Nishimura et al., 2012). ...
... Landoure et al., 2010). These different phenotypes may even occur within the same family (Auer-Grumbach et al., 2010) and might have an incomplete penetrance (Berciano et al., 2011). In addition, heterozygous TRPV4 mutations are responsible for various skeletal dysplasias (Nishimura et al., 2012). ...
Non-Cell-Autonomous Regulation of Root Hair
... and that the YFP-WRKY75 fusion protein is functional (Supplemental Table S3). The WRKY75 transcript levels of plants carrying this construct in the wrky75-25 background are lower than in Col-0 (Supplemental Fig. S6). This excludes the possibility that artificially high expression levels lead to the r ...
... and that the YFP-WRKY75 fusion protein is functional (Supplemental Table S3). The WRKY75 transcript levels of plants carrying this construct in the wrky75-25 background are lower than in Col-0 (Supplemental Fig. S6). This excludes the possibility that artificially high expression levels lead to the r ...
Supporting Information Parfenov et al. 10.1073/pnas.1416074111
... million reads mapped) across 70% of the patient samples as not expressed (white with black outline in Fig. 2 and Figs. S4 and S5). For graphical representation of exon expression levels, we mean-centered the RPKM values and divided by their SD for each exon. The lengths of the composite exons were t ...
... million reads mapped) across 70% of the patient samples as not expressed (white with black outline in Fig. 2 and Figs. S4 and S5). For graphical representation of exon expression levels, we mean-centered the RPKM values and divided by their SD for each exon. The lengths of the composite exons were t ...
How to determine recessive-lethal mutation rates. David D. Perkins Background
... made it possible for H. J. Muller (1927) to demonstrate that X rays are mutagenic, a finding which led to the Nobel Prize. Muller's method using the ClB chromosome depended on the suppression of crossing over by a heterozygous inversion. which kept the irradiated X chromosome intact through a cross, ...
... made it possible for H. J. Muller (1927) to demonstrate that X rays are mutagenic, a finding which led to the Nobel Prize. Muller's method using the ClB chromosome depended on the suppression of crossing over by a heterozygous inversion. which kept the irradiated X chromosome intact through a cross, ...
Evaluation of the phylogenetic position of the planctomycete
... gamma distribution of evolutionary rates with four categories. Visualization of trees was accomplished with ARB (http://www. arb-home.de/). Genome trees. Genome trees were calculated from normalized BLASTP scores (Clarke et al., 2002). In brief, all 231 509 ORFs were searched against each other usin ...
... gamma distribution of evolutionary rates with four categories. Visualization of trees was accomplished with ARB (http://www. arb-home.de/). Genome trees. Genome trees were calculated from normalized BLASTP scores (Clarke et al., 2002). In brief, all 231 509 ORFs were searched against each other usin ...
White Paper: DMET™ Plus allele translation
... frequency. Consequently, the gene tables may not fully describe all genetic diversity. The DMET™ Console Software translation engine therefore assumes that these undefined haplotypes may indeed exist as unknown alleles (reported as “UNK”). Diplotypes with UNK calls are reported as alternative result ...
... frequency. Consequently, the gene tables may not fully describe all genetic diversity. The DMET™ Console Software translation engine therefore assumes that these undefined haplotypes may indeed exist as unknown alleles (reported as “UNK”). Diplotypes with UNK calls are reported as alternative result ...
Munchkin Cat
... World War but other short-legged cats were spotted in Russia during 1956 and the United States in the 1970s. In Russia the cat earned the nickname "Stalingrad Kangaroo cat". In 1983 Sandra Hochenedel, a music teacher in Louisiana, found two pregnant cats who had been chased by a bulldog under a truc ...
... World War but other short-legged cats were spotted in Russia during 1956 and the United States in the 1970s. In Russia the cat earned the nickname "Stalingrad Kangaroo cat". In 1983 Sandra Hochenedel, a music teacher in Louisiana, found two pregnant cats who had been chased by a bulldog under a truc ...
Document
... of pancakes of different sizes • The waiter wants to rearrange them (so that the smallest winds up on top, and so on, down to the largest at the bottom) • He does it by flipping over several from the top, repeating this as many times as necessary ...
... of pancakes of different sizes • The waiter wants to rearrange them (so that the smallest winds up on top, and so on, down to the largest at the bottom) • He does it by flipping over several from the top, repeating this as many times as necessary ...
Reduced expression of the SHORT-ROOT gene increases the rates
... role in root meristem formation and maintenance and in the cambial region of hypocotyl cuttings [8]. In Populus trichocarpa, PtSHR1 is a close homolog of the Arabidopsis RAM regulator, AtSHR, and its expression has been detected in the VC of rapidly growing stems of hybrid poplar [9]. Another relate ...
... role in root meristem formation and maintenance and in the cambial region of hypocotyl cuttings [8]. In Populus trichocarpa, PtSHR1 is a close homolog of the Arabidopsis RAM regulator, AtSHR, and its expression has been detected in the VC of rapidly growing stems of hybrid poplar [9]. Another relate ...
Inclusive fitness and the sociobiology of the genome
... Note that when carriers interact only with other carriers (so-called greenbeards), then r = 1, so Hamilton’s rule (1) is satisfied exactly when b [ c. The fact that greenbeards are necessarily prosocial in the sense of increasing mean population fitness was first pointed out by Ridley and Grafen (19 ...
... Note that when carriers interact only with other carriers (so-called greenbeards), then r = 1, so Hamilton’s rule (1) is satisfied exactly when b [ c. The fact that greenbeards are necessarily prosocial in the sense of increasing mean population fitness was first pointed out by Ridley and Grafen (19 ...
org.Mm.eg.db
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
A WK-Means Approach for Clustering
... comparison among WK-means and ICA [2] ACO [21], PSO [12], SA [19], GA [13], TS and K-means [17, 19], for 100 runs on four real-instances datasets. The best centroid found by the proposed algorithm is also shown in Tables 2, 4, 6 and 8. For comparison of the results, in the Iris dataset, the best, av ...
... comparison among WK-means and ICA [2] ACO [21], PSO [12], SA [19], GA [13], TS and K-means [17, 19], for 100 runs on four real-instances datasets. The best centroid found by the proposed algorithm is also shown in Tables 2, 4, 6 and 8. For comparison of the results, in the Iris dataset, the best, av ...
Inferring Host Gene Subnetworks Involved in Viral
... node. The connecting edges in the graph provide a simplified representation of known interactions among the nodes. Figure 1(B) presents a graphical guide to the network elements used by our method. The color of a gene node specifies the observed phenotype when expression of the gene’s product is sup ...
... node. The connecting edges in the graph provide a simplified representation of known interactions among the nodes. Figure 1(B) presents a graphical guide to the network elements used by our method. The color of a gene node specifies the observed phenotype when expression of the gene’s product is sup ...
Genetic Recombination in Pseudomonas aeruginosa
... whether or not prototroph formation will take place. Double biochemical mutants were made for strains 1 and L. The primary mutants used were l(Tl-), l(M1-), l(LIL-), L(IVl--). The mutants obtained were l(Tl-LIL-), l(Tl-A-), l(Ml-H-), l(Ml-Tl-), l(LIL-Tl-), L(IV,-L-), L(IVl-Se-), L(IVl-Tl-). Crosses ...
... whether or not prototroph formation will take place. Double biochemical mutants were made for strains 1 and L. The primary mutants used were l(Tl-), l(M1-), l(LIL-), L(IVl--). The mutants obtained were l(Tl-LIL-), l(Tl-A-), l(Ml-H-), l(Ml-Tl-), l(LIL-Tl-), L(IV,-L-), L(IVl-Se-), L(IVl-Tl-). Crosses ...
From bedside to bench: how to analyze a splicing
... The number of mutations occurring at the pre-mRNA splicing level have risen to an extent where databases partially or totally dedicated to collecting mRNA splicing defects now exist. Probably the most publicized example is the Human Gene Mutation Database (HGMD) that acts as a general repository of ...
... The number of mutations occurring at the pre-mRNA splicing level have risen to an extent where databases partially or totally dedicated to collecting mRNA splicing defects now exist. Probably the most publicized example is the Human Gene Mutation Database (HGMD) that acts as a general repository of ...
Isolation and characterization of a repeated sequence (RPS1) of
... aqueous phases were mixed with 2 vols 99% (v/v) ethanol. After storage at - 20 "C overnight, the precipitates were removed and washed once with 70% ethanol. Dried precipitates were dissolved in 8 ml TE (10 mM-Tris/HCl, 1 mM-EDTA, pH 8.0) and stored at 4 "C. Southern hybridizations. Southern hybridiz ...
... aqueous phases were mixed with 2 vols 99% (v/v) ethanol. After storage at - 20 "C overnight, the precipitates were removed and washed once with 70% ethanol. Dried precipitates were dissolved in 8 ml TE (10 mM-Tris/HCl, 1 mM-EDTA, pH 8.0) and stored at 4 "C. Southern hybridizations. Southern hybridiz ...
Liver Effects of Clinical Drugs Differentiated in Human Liver
... In this study, the ex vivo human liver slice model was used to characterize the initial effects of drugs associated with liver adverse effects clinically which encompass diverse mechanisms contributing to liver dysfunction and injury. All drugs were dosed daily and compared side-by-side within each ...
... In this study, the ex vivo human liver slice model was used to characterize the initial effects of drugs associated with liver adverse effects clinically which encompass diverse mechanisms contributing to liver dysfunction and injury. All drugs were dosed daily and compared side-by-side within each ...